Exact Mass: 253.0326
Exact Mass Matches: 253.0326
Found 425 metabolites which its exact mass value is equals to given mass value 253.0326,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
L-Threoneopterin
L-Threoneopterin is a catabolic product of GTP. It is synthesized by macrophages upon stimulation by interferon-gamma. It is used as a marker of HIV infection. It belongs to the chemical group known as pterins. Neopterin is a pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections (From Stedman, 26th ed). Neopterin also serves as a precursor in the biosynthesis of biopterin. Neopterin is a catabolic product of GTP. It is synthesised by macrophages upon stimulation with interferon-gamma. It is used as a marker of HIV infection. It belongs to the chemical group known as pterins.A pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin. [HMDB] Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.
Sulfamethoxazole
Sulfamethoxazole is only found in individuals that have used or taken this drug. It is a bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides. J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01EC - Intermediate-acting sulfonamides COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides CONFIDENCE standard compound; EAWAG_UCHEM_ID 298 CONFIDENCE standard compound; INTERNAL_ID 1018 Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
Tizanidine
Tizanidine is a short-acting drug for the management of spasticity. Tizanidine is an agonist at a2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons. Tizanidine has two major metabolites: (1) 5-chloro-4-(2-imidazolin-4-on-2-ylamino)-2,1,3-benzothiazdiazole and (2) 5-chloro-4-(2-imidazolin-4-on-2-ylamino)-2,1,3-benzothiadiazole (PMID: 9929503, 19961320). M - Musculo-skeletal system > M03 - Muscle relaxants > M03B - Muscle relaxants, centrally acting agents D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents D002491 - Central Nervous System Agents > D000927 - Anticonvulsants D002491 - Central Nervous System Agents > D000700 - Analgesics Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. Target: α2-adrenergic receptor Tizanidine is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is also prescribed off-label for migraine headaches, as a sleep aid, and as an anticonvulsant. It is also prescribed for some symptoms of fibromyalgia. Tizanidine has been found to be as effective as other antispasmodic drugs and has superior tolerability to that of baclofen and diazepam. Tizanidine can be very strong even at the 2 mg dose and may cause hypotension, so caution is advised when it is used in patients who have a history of orthostatic hypotension, or when switching from gel cap to tablet form and vice versa. Tizanidine can occasionally cause liver damage, generally the hepatocellular type. Clinical trials show that up to 5\% of patients treated with tizanidine had elevated liver function test values, though symptoms disappeared upon withdrawal of the drug. Care should be used when first beginning treatment with tizanidine with regular liver tests for the first 6 months of treatment.
(2-Mercaptomethyl-3-phenyl-propionyl)-glycine
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors
D-erythro-Eritadenine
D-erythro-Eritadenine is found in mushrooms. D-erythro-Eritadenine is isolated from the edible shitake mushroo D004791 - Enzyme Inhibitors
N-Salicyloylaspartic acid
Constituent of kidney beans (Phaseolus vulgaris) and grape (Vitis subspecies). N-Salicyloylaspartic acid is found in many foods, some of which are green bean, yellow wax bean, pulses, and fruits. N-Salicyloylaspartic acid is found in fruits. N-Salicyloylaspartic acid is a constituent of kidney beans (Phaseolus vulgaris) and grape (Vitis species).
Neopterin
Neopterin, also known as monapterin, belongs to the class of organic compounds known as biopterins and derivatives. These are coenzymes containing a 2-amino-pteridine-4-one derivative and are mainly synthesized in several parts of the body, including the pineal gland. Neopterin is a solid that is soluble in water. Neopterin is a catabolic product of guanosine triphosphate (GTP). In humans, it is involved in pterine biosynthesis and it also serves as a precursor in the biosynthesis of biopterin, which is an essential cofactor in neurotransmitter synthesis. Neopterin has been identified as a uremic toxin according to the European Uremic Toxin Working Group (PMID: 22626821). Most uremic toxins are metabolic waste products and are normally excreted in the urine or feces. Uremic toxins can cause kidney, liver and heart damage. They can also cause changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma. Uremic toxins such as neopterin are actively transported into the kidneys via organic ion transporters (especially OAT3). Elevated levels of neopterin result from immune system activation, including from malignant cancer, allograft rejection, viral infection, and autoimmune disorders (PMID: 19500901). Measurement of neopterin concentration allows estimation of the extent of oxidative stress elicited by the immune system. Neopterin concentrations usually correlate with the extent and activity of a given disease, and are also used to monitor the course of the disease. Elevated neopterin concentrations are among the best predictors of adverse outcome in patients with HIV infection, in cardiovascular disease, and in various types of cancer. Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.
Umanopterin
Umanopterin is a pteridine derivative. It is identified in body fluids. An elevated level of umanopterin is associated with immune system activation, malignant diseases, allograft rejection, and viral infections. (http://www.online-medical-dictionary.org/) [HMDB] Umanopterin is a pteridine derivative. It is identified in body fluids. An elevated level of umanopterin is associated with immune system activation, malignant diseases, allograft rejection, and viral infections (http://www.online-medical-dictionary.org/). Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.
Hydroxysepiapterin
3-hydroxysepiapterin is found in high concentration in the urine of patients with DHBS(dihydrobiopterin synthetase ) deficiency.(PMID: 7005193) [HMDB] 3-hydroxysepiapterin is found in high concentration in the urine of patients with DHBS(dihydrobiopterin synthetase) deficiency.(PMID: 7005193).
2-(1,2,3,4-Tetrahydroxybutyl)thiazolidine-4-carboxylic acid
3'-AZIDO-2',3'-DIDEOXYURIDINE
Cridanimod
L - Antineoplastic and immunomodulating agents > L03 - Immunostimulants > L03A - Immunostimulants D007155 - Immunologic Factors > D007369 - Interferon Inducers C2140 - Adjuvant
Deferitrin
Furegrelate
C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D004791 - Enzyme Inhibitors C471 - Enzyme Inhibitor
[(2R,3R,4R)-3,4,5-Trihydroxy-1-oxopentan-2-yl] (2R)-2-amino-3-sulfanylpropanoate
4-[2-(4-chlorophenyl)ethylamino]-4-oxobut-2-enoic acid
4-(1,1-dioxido-2,3-dihydro-1-benzothien-3-yl)morpholine
Viridicatol
CONFIDENCE Penicillium sp. Viridicatol, a quinolinone alkaloid, is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum. Viridicatol has strong antifungal activity against Staphylococcus aureus with MIC value of 15.6 μg/mL[1].
5-(3,3-dichloro-2-methylpropyl)-4-hydroxy-3,3-dimethyl-2-pyrrolidinone|dysidamide C
(Z)-O-methyltridentatol B|S,S-dimethyl (Z)-2-(4-methoxyphenyl)ethenyliminodithiocarbonate
sulfamethoxazole
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01EC - Intermediate-acting sulfonamides An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position. COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS CONFIDENCE Reference Standard (Level 1); HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu); Flow Injection CONFIDENCE Reference Standard (Level 1); HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu) CONFIDENCE standard compound; INTERNAL_ID 2343 CONFIDENCE standard compound; INTERNAL_ID 8563 CONFIDENCE Reference Standard (Level 1) CONFIDENCE standard compound; INTERNAL_ID 1018
3-hydroxy-4-(3-hydroxyphenyl)-1H-quinolin-2-one
1-(4-BROMOPHENYL)-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE
POTASSIUM TRIFLUORO(6-(TRIFLUOROMETHYL)PYRIDIN-3-YL)BORATE
Methyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)acetate
1-(4-FLUOROBENZOYL)-4-HYDROXY-2-PYRROLIDINECARBOXYLICACID
4H-Pyrano[2,3-b]pyridin-4-one, 2-(4-methoxyphenyl)-
6-Bromo-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one
4-Hydroxy-7-methylamino-2-naphthalenesulfonic acid
2-Thioxo-3-thiazolidinecarboxylic acid benzyl ester
4-hydroxy-6-methylamino-2-naphthalene sulfonic acid
navuridine
D009676 - Noxae > D000963 - Antimetabolites > D015224 - Dideoxynucleosides 3′-Azido-2′,3′-dideoxyuridine (AzdU) is a nucleoside analog of Zidovudine (HY-17413). 3′-Azido-2′,3′-dideoxyuridine is a potent inhibitor of human immunodeficiency virus (HIV) replication in human peripheral blood mononuclear cells (PBMC) with limited toxicity for human bone marrow cells (BMC)[1][2][3]. 3′-Azido-2′,3′-dideoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
4(1H)-Pyrimidinone,6-amino-1-(4-chlorophenyl)-2,3-dihydro-2-thioxo-
5-(ethoxycarbonylamino)benzene-1,3-dicarboxylic acid
4-(4-CHLOROPHENYL)-2-METHYL-5-THIAZOLECARBOXYLIC ACID
c-(2-chloro-phenyl)-c-phenyl-methylamine hydrochloride
METHYL 3,3,3-TRIFLUORO-N-(TRIFLUOROACETYL)ALANINATE
1-(4-bromophenyl)-3-(dimethylamino)prop-2-en-1-one
3-Pyridinecarboxylic acid, 2-chloro-5-(trifluoromethyl)-, ethyl ester
2-BENZO[D]1,3-DIOXOLEN-5-YL-1,3-THIAZOLIDINE-4-CARBOXYLICACID
(3-CHLORO-[1,1-BIPHENYL]-4-YL)METHANAMINE HYDROCHLORIDE
7-bromo-1,4,4-triMethyl-1,2,3,4-tetrahydroquinoline
2-(chloromethyl)-5-(3-methyl-4-nitrophenyl)-1,3,4-oxadiazole
2-[2-(2-CHLOROETHOXY)ETHYL]-1H-ISOINDOLE-1,3(2H)-DIONE
7-bromo-3,4-dihydro-1H-isoquinoline-2-carboximidamide
n-acetyl-s-benzyl-l-cysteine
The S-benzyl derivative of N-acetyl-L-cysteine.
methyl 1-[(2,6-difluorophenyl)methyl]triazole-4-carboxylate
7-CHLORO-IMIDAZO[1,2-B]PYRIDAZINE-2-CARBOXYLIC ACID, TERT-BUTYL ESTER
(4-Chloro-3-(pyrrolidine-1-carbonyl)phenyl)boronic acid
(3-Chloro-4-(pyrrolidine-1-carbonyl)phenyl)boronic acid
3-Pyrrolidinecarboxylic acid, 1-[(4-chlorophenyl)methyl]-5-oxo-
2-(4-chlorophenyl)-1-methyl-5-oxopyrrolidine-3-carboxylic acid
2-(HydroxyMethyl)-6-[4-(trifluoromethyl)phenyl]pyridine
6-bromo-1,4,4-triMethyl-1,2,3,4-tetrahydroquinoline
ETHYL 5,8-DIFLUORO-4-OXOHYDROQUINOLINE-3-CARBOXYLATE
2-(d-arabino-tetrahydroxybutyl)-4(r)-1,3-thiazolidine-4-carboxylic acid
ETHYL 4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLATE
2-(4-BROMO-PHENYL)-4,4-DIMETHYL-4,5-DIHYDRO-OXAZOLE
6-(4-methylbenzenesulfonyl)-2-oxa-6-azaspiro[3.3]heptane
6-Bromo-2,2-spirocyclopentane-2,3-dihydro-1H-imidazo[4,5-b]pyridine
6-(trifluoromethyl)-2,3,4,9-tetrahydrocarbazol-1-one
2-[2-(2,3-dimethylanilino)-2-oxoethyl]sulfanylacetate
Vanitiolide
C78276 - Agent Affecting Digestive System or Metabolism > C66913 - Cholagogues or Choleretic Agents
Ethyl 6,8-difluoro-4-hydroxyquinoline-3-carboxylate
1-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-N,N-dimethylmethanamine
Ethyl 4-chloro-5-ethylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
4-Chloro-7-fluoroquinoline-3-carboxylic acid ethyl ester
4-Chloro-N-(4-chlorophenyl)-6-methyl-2-pyrimidinamine
2-NITRO-5-AMINO-3-(ACETYL-AMINO)-4-METHYLBENZOIC ACID
3-Amino-5-(4-chlorophenyl)thiophene-2-carboxylic acid
Methyl 3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate
C-(3-CHLORO-PHENYL)-C-PHENYL-METHYLAMINE HYDROCHLORIDE
(6-[3-(TRIFLUOROMETHYL)PHENYL]PYRIDIN-3-YL)METHANOL
ETHYL 2-AMINO-4-(2-THIENYL)THIOPHENE-3-CARBOXYLATE
1-ISOPROPYL-7-(METHYLTHIO)-1H-PYRIMIDO[4,5-D][1,3]OXAZINE-2,4-DIONE
7-(METHYLTHIO)-1-PROPYL-1H-PYRIMIDO[4,5-D][1,3]OXAZINE-2,4-DIONE
1H-Pyrrolo[2,3-b]pyridine-3-propanoic acid, a-amino-6-chloro-4-Methyl-
2-(4-Bromo-1H-pyrrolo[2,3-b]pyridin-2-yl)acetamide
1-(4-Bromo-1H-pyrrolo[2,3-b]pyridin-2-yl)-N,N-dimethylmethanamine
ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
[4-(4-Chlorophenyl)phenyl]methylamine hydrochloride
2-(CHLOROMETHYL)-5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4-AMINE
[4-[(methylcarbamothioylamino)carbamoyl]phenyl]boronic acid
3-(6-Chloro-4-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-D-alanine
1-(4-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-N,N-dimethylmethanamine
3-(Carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid
1-(4-FLUOROPHENYL)-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINEHYDROCHLORIDE
1-(7-bromo-3,4-dihydro-1H-isoquinolin-2-yl)ethanone
[4-(2-chlorophenyl)phenyl]methylamine hydrochloride
(6-[4-(trifluoromethyl)phenyl]pyridin-3-yl)methanol
1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, 5-bromo-N-Methyl-
7-BROMO-4,4-DIMETHYL-3,4-DIHYDROQUINOLIN-2(1H)-ONE
ethyl 4-chloro-6-(trifluoromethyl)pyridine-2-carboxylate
2-BROMO-1-[3,4-DIHYDRO-1(2H)-QUINOLINYL]-1-ETHANONE
3-(4-fluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride
2-(4-chlorophenyl)-4-methyl-1,3-thiazole-5-carboxylic acid
ethyl 7-amino-2-(methylthio)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
3-(2-Methyl-5-nitro-1,3-benzodioxol-2-yl)propanoic acid
2-methyl-4-(3-chloro)phenyl thiazole-5-carboxylic acid
(2Z)-6-Hydroxy-7-methyl-2-(pyridin-3-ylmethylene)-1-benzofuran-3(2H)-one
(1-Imidazo[2,1-b][1,3]thiazol-6-ylpropyl)amine dihydrochloride
6-bromo-2-ethyl-8-methylimidazo[1,2-a]pyridin-3-amine
trans-1-(3-Bromophenyl)-3-dimethylamino-2-propen-1-one
3-[3-(Trifluoromethyl)phenoxy]-azetidine hydrochloride
N-[(2-Methyl-5-nitrophenyl)carbamothioyl]acetamide
5-(4-ETHOXY-PHENYLAMINO)-[1,3,4]THIADIAZOLE-2-THIOL
5-(Chloromethyl)-N-phenyl-1,3,4-thiadiazole-2-carboxamide
5-(2-ETHOXY-PHENYLAMINO)-[1,3,4]THIADIAZOLE-2-THIOL
Ethyl 4-chloro-5-(trifluoromethyl)-pyridine-2-carboxylate
6-(TRIFLUOROMETHOXY)-1H-BENZIMIDAZOL-2-AMINEHYDROCHLORIDE
N-1-[3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]PROPANE-1,3-DIAMINE
Ethyl4-Methyl-2-(thiophen-2-yl)thiazole-5-carboxylate
m-(4,5-dihydro-5-imino-3-methyl-1H-pyrazol-1-yl)benzenesulphonic acid
N-methyl-N-[3-(trifluoromethyl)phenyl]carbamothioyl chloride
2-(1,2,3,4-Tetrahydroxybutyl)thiazolidine-4-carboxylic acid
5-(Hydroxyimino)-6-oxo-5,6-dihydronaphthalene-2-sulfonic acid
4-Amino-N-(4-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide
2-(2-Bromophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole
3-{[(1R)-1-Benzyl-2-sulfanylethyl]amino}-3-oxopropanoic acid
Cridanimod
L - Antineoplastic and immunomodulating agents > L03 - Immunostimulants > L03A - Immunostimulants D007155 - Immunologic Factors > D007369 - Interferon Inducers C2140 - Adjuvant
Erythroneopterin
Neopterin is a catabolic product of guanosine triphosphate (GTP), a purine nucleotide. Neopterin belongs to the chemical group known as pteridines. It is synthesised by macrophages upon stimulation with the cytokine interferon-gamma and is indicative of a pro-inflammatory immune status. Neopterin serves as a marker of cellular immune system activation. [Wikipedia]. Erythroneopterin is found in soy bean. Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.
N(omega)-phosphonato-L-arginine
Conjugate base of N(omega)-phospho-L-arginine having anionic carboxy and phosphate groups and protonated amino and guanidino nitrogens.
5-(3-Carboxy-3-oxopropenyl)-4,6-dihydroxypicolinate
[(2R,3R,4R)-3,4,5-Trihydroxy-1-oxopentan-2-yl] (2R)-2-amino-3-sulfanylpropanoate
Daidzein(1-)
A flavonoid oxoanion obtained by deprotonation of the 7-hydroxy group of daidzein. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.).
4-butyl-3-(3-methyl-2-thiophenyl)-1H-1,2,4-triazole-5-thione
(2S)-2-azaniumyl-5-oxo-5-[(2-sulfonatoethyl)amino]pentanoate
3-Cyano-8-hydroxymethyl-4-methoxymethylazulene-1-carboxylic acid lactone
tizanidine
M - Musculo-skeletal system > M03 - Muscle relaxants > M03B - Muscle relaxants, centrally acting agents D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents D002491 - Central Nervous System Agents > D000927 - Anticonvulsants D002491 - Central Nervous System Agents > D000700 - Analgesics Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. Target: α2-adrenergic receptor Tizanidine is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is also prescribed off-label for migraine headaches, as a sleep aid, and as an anticonvulsant. It is also prescribed for some symptoms of fibromyalgia. Tizanidine has been found to be as effective as other antispasmodic drugs and has superior tolerability to that of baclofen and diazepam. Tizanidine can be very strong even at the 2 mg dose and may cause hypotension, so caution is advised when it is used in patients who have a history of orthostatic hypotension, or when switching from gel cap to tablet form and vice versa. Tizanidine can occasionally cause liver damage, generally the hepatocellular type. Clinical trials show that up to 5\% of patients treated with tizanidine had elevated liver function test values, though symptoms disappeared upon withdrawal of the drug. Care should be used when first beginning treatment with tizanidine with regular liver tests for the first 6 months of treatment.
5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one
D-Monapterin
Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.
FUREGRELATE
C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D004791 - Enzyme Inhibitors C471 - Enzyme Inhibitor
glutaurine(1-)
An organosulfonate oxoanion resulting from the deprotonation of the sulfonic acid moiety of glutaurine zwitterion. The major species at pH 7.3.
(S)-(-)-5-Fluorowillardiine (hydrochloride)
(S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific AMPAR agonist.
1,2,6-trihydroxy-3-methoxy-5-[(1e)-prop-1-en-1-yl]pyrano[3,2-b]pyrrol-7-one
1,2,6-trihydroxy-3-methoxy-5-(prop-1-en-1-yl)pyrano[3,2-b]pyrrol-7-one
(2r)-2-{[hydroxy(2-hydroxyphenyl)methylidene]amino}butanedioic acid
7-hydroxybiopterin
{"Ingredient_id": "HBIN013270","Ingredient_name": "7-hydroxybiopterin","Alias": "NA","Ingredient_formula": "C9H11N5O4","Ingredient_Smile": "CC(C(C1=NC2=C(NC1=O)NC(=NC2=O)N)O)O","Ingredient_weight": "0","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "9852","TCMSP_id": "NA","TCM_ID_id": "21434","PubChem_id": "NA","DrugBank_id": "NA"}
