Cridanimod (BioDeep_00000858662)

   

Volatile Flavor Compounds


代谢物信息卡片


2-(9-Oxoacridin-10(9H)-yl)acetic acid

化学式: C15H11NO3 (253.0738896)
中文名称: 吖啶酮乙酸, 克瑞达莫德
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3N2CC(=O)O
InChI: InChI=1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)

描述信息

L - Antineoplastic and immunomodulating agents > L03 - Immunostimulants > L03A - Immunostimulants
D007155 - Immunologic Factors > D007369 - Interferon Inducers
C2140 - Adjuvant

同义名列表

3 个代谢物同义名

2-(9-Oxoacridin-10(9H)-yl)acetic acid; Cridanimod; Cridanimod



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
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  • M G Romantsov, F I Ershov, A L Kovalenko, D S Sukhanov, O M Liberanskaia. [Virus infections and interferon inducers in the complex therapy]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 2013; 58(5-6):49-54. doi: NULL. [PMID: 24757825]
  • V M Frolov, N A Peresadin, R B Chkhetiani, O V Kruglova. [Efficiency of cycloferon and reamberin combination at the treatment of the patients with chronic sepsis]. Georgian medical news. 2012 Apr; ?(205):44-51. doi: NULL. [PMID: 22665731]
  • V M Frolov, N A Peresadin, V A Tereshin, R B Chkhetiani, O V Kruglova. [Pathogenetic ground of including reamberin and cycloferon combination into the therapy program for patients with severe cases of acute tonsillitis of a mixed viral/bacterial etiology]. Georgian medical news. 2012 Mar; ?(204):49-58. doi: NULL. [PMID: 22573749]
  • M G Romantsov, I Iu Mel'nikova, I V Sarvilina. [Frequently ill child syndrome]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 2012; 57(9-10):8-16. doi: NULL. [PMID: 23477215]
  • V R Demenkov, V M Frolov, N A Peresadin, O V Kruglova. [Influence of сycloferon on the сytokine blood profile and production of proinflammatory сytokines in the cultures of mononucleares of peripheral blood of the patients with chronic tonsillitis]. Vestnik otorinolaringologii. 2012; ?(4):73-6. doi: NULL. [PMID: 23011379]
  • V M Frolov, Ia A Sotskaia, O V Kruglova. [Influence of immunotropic preparation cycloferon and phytopreparations of Cynara scolimus L. on blood cytokines profile of the patients with chronic viral hepatitis C in medical rehabilitation period]. Likars'ka sprava. 2012 Jan; ?(1-2):102-7. doi: NULL. [PMID: 23035608]
  • I V Sarvilina, M G Romantsov. [Proteomic profile and non-specific immunoprophylaxis of respiratory diseases in frequently sick children]. Vestnik Rossiiskoi akademii meditsinskikh nauk. 2012; ?(2):69, 71-4. doi: NULL. [PMID: 22642181]
  • V M Frolov, Ia A Sotskaia. [Efficacy of combined immunocorrection in the treatment of chronic viral hepatitis C]. Terapevticheskii arkhiv. 2012; 84(6):60-5. doi: NULL. [PMID: 22997921]
  • M M Liubishin, K V Sivak, T N Savateeva-Liubimova. [Experimental justification of approaches to pharmacological correction of delayed disorders caused by acute ethylene glycol poisoning]. Eksperimental'naia i klinicheskaia farmakologiia. 2012; 75(11):31-4. doi: NULL. [PMID: 23323331]
  • D S Sukhanov, M G Romantsov, A N Smagina, A L Kovalenko, O M Lokteva. [Dose-dependent interferon-induction activity and pharmacokinetics of cycloferon in healthy humans]. Eksperimental'naia i klinicheskaia farmakologiia. 2012; 75(1):23-6. doi: NULL. [PMID: 22442959]
  • V M Frolov, V A Tereshin, Ia A Sotskaia, O V Kruhlova. [Efficiency of modern immunoactive preparation cycloferon at coplex therapy of the patients with nonalcoholic steatohepatitis combined with irritable bowel syndrome]. Likars'ka sprava. 2011 Jul; ?(5-6):95-8. doi: NULL. [PMID: 22606899]
  • N V Tsiskarishvili, L N Nadareishvili, Ts I Tsiskarishvili. [New possibilities for elimination of human papillomavirus from the organism]. Georgian medical news. 2011 Mar; ?(192):34-8. doi: ". [PMID: 21525537]
  • A V Gordeets, E N Iurusova, A N Smagina, S L Piskunova. [Clinicoimmunological monitoring of therapy in patients with associated forms of yersiniosis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 2011; 56(5-6):49-53. doi: NULL. [PMID: 22145231]
  • O G Khlamova, A A Shul'diakov, A V Lepilin. [Improvement of herpetic stomatitis therapy in patients with chronic tonsillitis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 2011; 56(7-8):34-6. doi: ". [PMID: 22359868]
  • D K Vasil'eva, L G Goriacheva, N E Monakhova. [Characteristics of immune response to etiotropic and pathogenetic therapy in children with chronic hepatitis C]. Eksperimental'naia i klinicheskaia farmakologiia. 2011; 74(12):33-5. doi: ". [PMID: 22379880]
  • L D Kuntsevich, N N Komov, E V Shibaeva, V D Komarova, T V Kopytova, E I Pyshkina, N A Shchelchkova. [Focal immunophysiotherapy in combined treatment of men with manifestations of papilloma virus infection]. Urologiia (Moscow, Russia : 1999). 2010 Nov; ?(6):58-62. doi: NULL. [PMID: 21427998]
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  • A K Ivanov, A M Panteleev, D S Sukhanov, T V Sologub, M G Romanov. [The use of cycloferon in the combined treatment of tuberculosis patients infected with HIV and viral hepatitis]. Klinicheskaia meditsina. 2010; 88(5):49-52. doi: NULL. [PMID: 21089459]
  • L A Soboleva, A O Oseeva, A A Shul'diakov, N V Bulkina. [Improvement of parodontitis therapy of patients with HIV-infection]. Stomatologiia. 2010; 89(2):26-8. doi: ". [PMID: 20517247]
  • L A Soboleva, R R Siakin, E N Blinnikova, A A Shul'diakov, L M Pichugina. [Parodontitis immunotropic therapy in patients with chronic viral and bacterial infections]. Stomatologiia. 2010; 89(3):20-2. doi: ". [PMID: 20559229]
  • E P Liapina, L A Soboleva, A A Shul'diakov, S A Satarova, T A Perminova. [Efficacy of cycloferon in the treatment of brucellosis]. Klinicheskaia meditsina. 2010; 88(3):54-8. doi: ". [PMID: 20608067]
  • E A Aleksandrova, A V Lepilin, N E Kazimirova, A A Shul'diakov. [Optimization of parodontitis treatment of patients with tuberculosis]. Stomatologiia. 2010; 89(4):25-7. doi: ". [PMID: 21186645]
  • E I Zmushko, Iu A Mitin, V V Katsalukha, L P Sviridov, V P Nikolaev, V V Starenchenko. [Cytokinin inducing and antiviral activity of cycloferon on experimental herpetic infection]. Zhurnal mikrobiologii, epidemiologii i immunobiologii. 2003 Jul; ?(4):105-7. doi: NULL. [PMID: 12966893]
  • R V Razumnyĭ. [Pulmonary surfactant and blood serum in patients with chronic obstructive bronchitis on differentiated therapy]. Likars'ka sprava. 2002 Apr; ?(3-4):58-63. doi: NULL. [PMID: 12145894]
  • I V Maev, S S Grigorian, M G Gadzhieva, N I Ovchinnikova, T P Ospel'nikova, A N Kaziulin. [Interferon status of patients with non-specific ulcerous colitis and its correction with interferon inducers]. Terapevticheskii arkhiv. 2002; 74(2):31-5. doi: NULL. [PMID: 11899820]
  • V V Bul'on, L K Khnychenko, N S Sapronov, N N Kuznetsova, V B Anikin, R Iu arinenko, A L Kovalenko, L E Alekseeva. [Cycloferon in treating duodenal ulcers in rats]. Eksperimental'naia i klinicheskaia farmakologiia. 2001 Nov; 64(6):41-4. doi: ". [PMID: 11871237]
  • W Römer, E Tonew, W Schulze. Cyclic AMP metabolism and interferon induction in mice after treatment with 10-carboxymethyl-9-acridanone. Acta virologica. 1986 Sep; 30(5):411-7. doi: NULL. [PMID: 2431609]
  • N Miosga, W Römer. [Chemical-analytical characterization and determination of 10-carboxymethyl-9-acridanone]. Die Pharmazie. 1986 May; 41(5):326-8. doi: NULL. [PMID: 3737662]
  • E Piasecki, A D Inglot, J A Czyrski, Z Szulc, J Młochowski, B Narczewska. Interaction of sodium salt of 9-oxo-10-acridineacetic acid (CMA) and its analogs with serum albumin. A model for study on binding of the interferon inducer with receptor. Archivum immunologiae et therapiae experimentalis. 1985; 33(2):299-310. doi: NULL. [PMID: 2417573]
  • A D Inglot, J Młochowski, Z Szulc, O Inglot, M Albin. Induction of interferon in mice by sodium salt of 9-oxo-10-acridineacetic acid: specific enhancement by analogs. Archivum immunologiae et therapiae experimentalis. 1985; 33(2):275-85. doi: NULL. [PMID: 2417572]
  • G J Gorse, L M Slater, H S Kaplan, J G Tilles, T C Cesario. Inhibition of interferon yield by vincristine. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1984 Mar; 175(3):309-13. doi: 10.3181/00379727-175-41800. [PMID: 6694980]
  • J L Taylor, C K Schoenherr, S E Grossberg. High-yield interferon induction by 10-carboxymethyl-9-acridanone in mice and hamsters. Antimicrobial agents and chemotherapy. 1980 Jul; 18(1):20-6. doi: 10.1128/aac.18.1.20. [PMID: 6158292]