Classification Term: 559

Hydroquinolones (ontology term: CHEMONTID:0001716)

Compounds containing a hydrogenated quinoline bearing a ketone group." []

found 42 associated metabolites at category metabolite taxonomy ontology rank level.

Child Taxonomies: There is no child term of current ontology term.

1,2,5,6-Tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one

1,2,5,6-tetrahydro-4H-pyrrolo(3,2,1-Ij)quinolin-4-one (9ci)

1,2,5,6-Tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one is a fungicide against rice blast disease. Fungicide against rice blast disease

4-Hydroxyquinoline

1,4-dihydroquinolin-4-one

C9H7NO (145.0527612)

CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 53 CONFIDENCE standard compound; INTERNAL_ID 2492 KEIO_ID H139

Casimiroin

6-methoxy-9-methyl-2H,8H,9H-[1,3]dioxolo[4,5-h]quinolin-8-one

C12H11NO4 (233.0688046)

Casimiroin is found in pomes. Casimiroin is an alkaloid from the seed and bark of Casimiroa edulis (Mexican apple). Alkaloid from the seed and bark of Casimiroa edulis (Mexican apple). Casimiroin is found in pomes.

Graveoline

2-(2H-1,3-benzodioxol-5-yl)-1-methyl-1,4-dihydroquinolin-4-one

C17H13NO3 (279.0895388)

Graveoline is found in herbs and spices. Graveoline is an alkaloid from Ruta graveolens (rue). Alkaloid from Ruta graveolens (rue). Graveoline is found in herbs and spices. Graveoline (Rutamine) is an anti-cancer agent that can trigger apoptosis and autophagy in skin melanoma cells. Graveoline also exhibits antifungal activity[1]. Graveoline (Rutamine) is an anti-cancer agent that can trigger apoptosis and autophagy in skin melanoma cells. Graveoline also exhibits antifungal activity[1].

1-Methyl-2-nonyl-4(1H)-quinolinone

1-Methyl-2-nonyl-4(1H)-quinolinone; 1-Methyl-2-n-nonyl-4(1H) quinolone; 1-Methyl-2-nonyl-4(1H)-quinolone

C19H27NO (285.2092532)

1-Methyl-2-nonyl-4(1H)-quinolinone is a member of quinolines. 1-Methyl-2-nonylquinolin-4(1H)-one is a natural product found in Raulinoa echinata, Tetradium ruticarpum, and other organisms with data available. 1-Methyl-2-nonyl-4(1H)-quinolinone is found in herbs and spices. 1-Methyl-2-nonyl-4(1H)-quinolinone is an alkaloid from Ruta graveolens (rue

Ethoxyquin

6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline, 9ci, 8ci

C14H19NO (217.14665639999998)

Ethoxyquin is an antioxidant used in animal feeds and for the preservation of colour in the production of chili powder, paprika and ground chilli. Ethoxyquin is formerly used as an agricultural pesticide/herbicide, now superseded. Also used as a post-harvest dip for apples and pears to prevent scald. Antioxidant used in animal feeds and for the preservation of colour in the production of chili powder, paprika and ground chilli. Formerly used as an agricultural pesticide/herbicide, now superseded and is) also used as a post-harvest dip for apples and pears to prevent scald C26170 - Protective Agent > C275 - Antioxidant

Procaterol

8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(propan-2-yl)amino]butyl]-1,2-dihydroquinolin-2-one

C16H22N2O3 (290.16303419999997)

Procaterol is only found in individuals that have used or taken this drug. It is a long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation. [PubChem]Beta(2)-receptor stimulation in the lung causes relaxation of bronchial smooth muscle, bronchodilation, and increased bronchial airflow. R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03C - Adrenergics for systemic use > R03CC - Selective beta-2-adrenoreceptor agonists R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03A - Adrenergics, inhalants > R03AC - Selective beta-2-adrenoreceptor agonists D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists

2-Undecyl-4(1H)-quinolinone

2-undecyl-1,4-dihydroquinolin-4-one

C20H29NO (299.2249024)

2-Undecyl-4(1H)-quinolinone is found in herbs and spices. 2-Undecyl-4(1H)-quinolinone is an alkaloid from and roots of Ruta graveolens (rue) (as the main component of an inseparable mixture of 2-alkylquinolones contg. the 2-dodecyl, 2-tridecyl and 2-tetradecyl homologues) (Rutaceae). Alkaloid from and roots of Ruta graveolens (rue) (as the main component of an inseparable mixture of 2-alkylquinolones contg. the 2-dodecyl, 2-tridecyl and 2-tetradecyl homologues) (Rutaceae). 2-Undecyl-4(1H)-quinolinone is found in herbs and spices.

Schinifoline

4-methoxy-3-[(1E)-3-methylbuta-1,3-dien-1-yl]-1,2-dihydroquinolin-2-one

C15H15NO2 (241.110273)

Alkaloid from roots of Zanthoxylum simulans (Szechuan pepper). Schinifoline is found in herbs and spices and fruits. Schinifoline is found in fruits. Schinifoline is an alkaloid from roots of Zanthoxylum simulans (Szechuan pepper).

(S)-Edulinine

3-(2,3-dihydroxy-3-methylbutyl)-4-methoxy-1-methyl-1,2-dihydroquinolin-2-one

C16H21NO4 (291.1470506)

(S)-Edulinine is found in pomes. (S)-Edulinine is an alkaloid from the bark of Casimiroa edulis (Mexican apple

2-[4-(3,4-Methylenedioxyphenyl)butyl]-4(1H)-quinolinone

2-[4-(2H-1,3-benzodioxol-5-yl)butyl]-1,4-dihydroquinolin-4-one

C20H19NO3 (321.1364864000001)

2-[4-(3,4-Methylenedioxyphenyl)butyl]-4(1H)-quinolinone is found in herbs and spices. 2-[4-(3,4-Methylenedioxyphenyl)butyl]-4(1H)-quinolinone is an alkaloid from Ruta graveolens (rue

Murrayazolinine

2-{13,16-dimethyl-15-oxa-4-azapentacyclo[14.3.1.0²,¹⁴.0³,¹¹.0⁵,¹⁰]icosa-2(14),3(11),5(10),6,8,12-hexaen-19-yl}propan-2-ol

C23H27NO2 (349.2041682)

Murrayazolinine is found in herbs and spices. Murrayazolinine is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree

N-Methylschinifoline

4-methoxy-1-methyl-3-[(1E)-3-methylbuta-1,3-dien-1-yl]-1,2-dihydroquinolin-2-one

C16H17NO2 (255.12592220000002)

N-Methylschinifoline is found in fruits. N-Methylschinifoline is an alkaloid from roots of Zanthoxylum simulans (Szechuan pepper). Alkaloid from roots of Zanthoxylum simulans (Szechuan pepper). N-Methylschinifoline is found in herbs and spices and fruits.

Edulitine

4,8-dimethoxy-1,2-dihydroquinolin-2-one

C11H11NO3 (205.0738896)

Edulitine is found in pomes. Edulitine is an alkaloid from bark of Casimiroa edulis (Mexican apple

Cilostazol

6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2,3,4-tetrahydroquinolin-2-one

C20H27N5O2 (369.2164642)

Cilostazol is a medication used in the alleviation of the symptom of intermittent claudication in individuals with peripheral vascular disease. It is manufactured by Otsuka Pharmaceutical Co. under the trade name Pletal. Although drugs similar to cilostazol have increased the risk of death in patients with congestive heart failure, studies of significant size have not addressed people without the disease. [Wikipedia] B - Blood and blood forming organs > B01 - Antithrombotic agents > B01A - Antithrombotic agents > B01AC - Platelet aggregation inhibitors excl. heparin D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058987 - Phosphodiesterase 3 Inhibitors D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor D050299 - Fibrin Modulating Agents D020011 - Protective Agents

Nequinate

Methyl 6-butyl-1,4-dihydro-4-oxo-7-(phenylmethoxy)-3-quinolinecarboxylate, 9ci

C22H23NO4 (365.16269980000004)

C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent Antiprotozoan; used as a coccidiostat for poultry and rabbit

2-Undecyl-4(1H)-quinolinone N-oxide

1,4-dioxo-2-undecyl-1,4-dihydro-1λ⁵-quinolin-1-yl

C20H28NO2 (314.2119928)

2-Undecyl-4(1H)-quinolinone N-oxide is found in herbs and spices. 2-Undecyl-4(1H)-quinolinone N-oxide is isolated from roots of Ruta graveolens (rue). Isolated from roots of Ruta graveolens (rue). 2-Undecyl-4(1H)-quinolinone N-oxide is found in herbs and spices.

Pyronaridine

4-({7-chloro-2-methoxy-1H,5H-benzo[b]1,5-naphthyridin-10-yl}imino)-2,6-bis(pyrrolidin-1-ylmethyl)cyclohexa-2,5-dien-1-one

C29H32ClN5O2 (517.2244402)

Pyronaridine belongs to the family of Naphthyridines. These are compounds containing a naphthyridine moeity, a naphthalene in which a carbon atom has been replaced by a nitrogen in each of the two rings. The naphthyridine skeleton can also be described as an assembly two fused pyridine rings, which do not share their nitrogen atom.

1-Methyl-2-undecylquinolin-4(1H)-one

1-methyl-2-undecyl-1,4-dihydroquinolin-4-one

C21H31NO (313.2405516)

1,2-Dihydroquinoline

C9H9N (131.0734954)

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline

ethyl 2-ethoxy-1,2-dihydroquinoline-1-carboxylate

C14H17NO3 (247.1208372)

D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D009676 - Noxae > D000477 - Alkylating Agents

2'-Oxoquinidinone

4-{5-ethenyl-1-azabicyclo[2.2.2]octane-2-carbonyl}-6-methoxy-1,2-dihydroquinolin-2-one

C20H22N2O3 (338.16303419999997)

3-Fluoro-2-hydroxyquinoline

3-fluoro-1,2-dihydroquinolin-2-one

C9H6FNO (163.04333979999998)

2(1H)-Quinolinone, 3-methoxy-

3-methoxy-1,2-dihydroquinolin-2-one

C10H9NO2 (175.0633254)

3,4-Dehydrocilostazol

6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2-dihydroquinolin-2-one

C20H25N5O2 (367.200815)

8-Cyano-fluoroquinolone

3-fluoro-2-oxo-1,2-dihydroquinoline-8-carbonitrile

C10H5FN2O (188.0385892)

8-Methoxyquinolin-2(1H)-one

8-methoxy-1,2-dihydroquinolin-2-one

C10H9NO2 (175.0633254)

3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone

6-[(4-{[(3-methanesulfonylphenyl)methyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl)amino]-1,2,3,4-tetrahydroquinolin-2-one

C22H20F3N5O3S (491.1238886000001)

4'-Hydroxycilostazol, trans-

6-{4-[1-(4-hydroxycyclohexyl)-1H-1,2,3,4-tetrazol-5-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one

C20H27N5O3 (385.2113792)

Cilostamide

N-cyclohexyl-N-methyl-4-[(2-oxo-1,2-dihydroquinolin-6-yl)oxy]butanamide

C20H26N2O3 (342.19433260000005)

Decoquinate

ethyl 6-(decyloxy)-7-ethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate

C24H35NO5 (417.25151000000005)

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic

Dihydroevocarpine

1-methyl-2-tridecyl-1,4-dihydroquinolin-4-one

C23H35NO (341.27185000000003)

Dihydroevocarpine induces cytotoxicity in acute myeloid leukemia via suppressing the mTORC1/2 activity[1]. Dihydroevocarpine induces cytotoxicity in acute myeloid leukemia via suppressing the mTORC1/2 activity[1].

(Z)-1-Methyl-2-(tridec-8-en-1-yl)quinolin-4(1H)-one

1-methyl-2-(tridec-8-en-1-yl)-1,4-dihydroquinolin-4-one

C23H33NO (339.25620080000004)

Evodenoson

4-(3-(6-Amino-9-(5-cyclopropylcarbamoyl-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-yl)prop-2-ynyl)piperidine-1-carboxylic acid methyl ester

C23H29N7O6 (499.2179214)

Flosequinan

7-Fluoro-3-methanesulphinyl-1-methyl-1,4-dihydroquinolin-4-one

C11H10FNO2S (239.04162520000003)

C - Cardiovascular system > C01 - Cardiac therapy > C01D - Vasodilators used in cardiac diseases > C01DB - Quinolone vasodilators C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents

D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones

Methyl fluoroquinolone

3-fluoro-4-methyl-1,2-dihydroquinolin-2-one

C10H8FNO (177.05898899999997)

6,6'-Methylenebis(2,2-dimethyl-4-methanesulfonic acid-1,2-dihydroquinoline)

(6-{[2,2-dimethyl-4-(sulfomethyl)-1,2-dihydroquinolin-6-yl]methyl}-2,2-dimethyl-1,2-dihydroquinolin-4-yl)methanesulfonic acid

C25H30N2O6S2 (518.15452)

D020011 - Protective Agents > D000975 - Antioxidants

trifluoroquinolone

3,4,5-trifluoro-1,2-dihydroquinolin-2-one

C9H4F3NO (199.02449699999997)