LYSERGAMIDE (BioDeep_00001868617)

Main id: BioDeep_00000007206

 


代谢物信息卡片


LYSERGAMIDE

化学式: C16H17N3O (267.1372)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1CC(C=C2C1CC3=CNC4=CC=CC2=C34)C(=O)N
InChI: InChI=1S/C16H17N3O/c1-19-8-10(16(17)20)5-12-11-3-2-4-13-15(11)9(7-18-13)6-14(12)19/h2-5,7,10,14,18H,6,8H2,1H3,(H2,17,20)/t10-,14-/m1/s1

描述信息

An ergoline alkaloid comprising ergoline lacking hydrogens at positions 9 and 10 and also having a methyl group attached to the piperidine nitrogen.

同义名列表

2 个代谢物同义名

LYSERGAMIDE; Ergine



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 2 ADRA2A, CASP3
Endoplasmic reticulum membrane 1 CYP3A5
Nucleus 1 CASP3
cytosol 1 CASP3
dendrite 3 HTR1D, HTR2A, HTR6
nucleoplasm 1 CASP3
Cell membrane 6 ADRA2A, HTR1D, HTR2A, HTR3A, HTR6, ITPRIP
Cleavage furrow 1 HTR3A
Cell projection, axon 1 HTR2A
Multi-pass membrane protein 5 ADRA2A, HTR1D, HTR2A, HTR3A, HTR6
Synapse 4 HTR1D, HTR3A, HTR6, NPS
dendritic shaft 1 HTR2A
glutamatergic synapse 3 ADRA2A, CASP3, HTR2A
neuronal cell body 3 ADRA2A, CASP3, HTR2A
postsynapse 1 HTR3A
presynaptic membrane 1 HTR2A
Presynapse 1 HTR2A
plasma membrane 6 ADRA2A, HTR1D, HTR2A, HTR3A, HTR6, ITPRIP
Membrane 3 CYP3A5, HTR3A, ITPRIP
axon 1 HTR2A
basolateral plasma membrane 1 ADRA2A
caveola 1 HTR2A
intracellular membrane-bounded organelle 1 CYP3A5
Microsome membrane 1 CYP3A5
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 ITPRIP
Secreted 1 VIP
extracellular region 2 NPS, VIP
cytoplasmic vesicle 1 HTR2A
postsynaptic membrane 2 HTR2A, HTR3A
presynaptic active zone membrane 1 ADRA2A
GABA-ergic synapse 1 ADRA2A
Nucleus outer membrane 1 ITPRIP
nuclear outer membrane 1 ITPRIP
Postsynaptic cell membrane 1 HTR3A
receptor complex 1 ADRA2A
neuron projection 2 HTR3A, VIP
cilium 1 HTR6
serotonin-activated cation-selective channel complex 1 HTR3A
transmembrane transporter complex 1 HTR3A
Membrane, caveola 1 HTR2A
cell body fiber 1 HTR2A
Cell projection, dendrite 1 HTR2A
axon terminus 1 ADRA2A
postsynaptic density membrane 1 ADRA2A
neurofilament 1 HTR2A
death-inducing signaling complex 1 CASP3
dopaminergic synapse 1 ADRA2A
G protein-coupled serotonin receptor complex 1 HTR2A


文献列表

  • Kelcie N Britton, Chey R Steen, Kyle A Davis, Jessi K Sampson, Daniel G Panaccione. Contribution of a novel gene to lysergic acid amide synthesis in Metarhizium brunneum. BMC research notes. 2022 May; 15(1):183. doi: 10.1186/s13104-022-06068-2. [PMID: 35585609]
  • Abigail M Jones, Chey R Steen, Daniel G Panaccione. Independent Evolution of a Lysergic Acid Amide in Aspergillus Species. Applied and environmental microbiology. 2021 11; 87(24):e0180121. doi: 10.1128/aem.01801-21. [PMID: 34586904]
  • Simon D Brandt, Pierce V Kavanagh, Folker Westphal, Simon P Elliott, Jason Wallach, Alexander Stratford, David E Nichols, Adam L Halberstadt. Return of the lysergamides. Part III: Analytical characterization of N6 -ethyl-6-norlysergic acid diethylamide (ETH-LAD) and 1-propionyl ETH-LAD (1P-ETH-LAD). Drug testing and analysis. 2017 Oct; 9(10):1641-1649. doi: 10.1002/dta.2196. [PMID: 28342178]
  • Camille Ponté, Maryse Lapeyre-Mestre. [Psychoactive effects of 'legal high': About lysergic acid amide (LSA)]. Therapie. 2017 Oct; 72(5):605-608. doi: 10.1016/j.therap.2017.01.012. [PMID: 28457570]
  • Claudia Oellig. Lysergic acid amide as chemical marker for the total ergot alkaloids in rye flour - Determination by high-performance thin-layer chromatography-fluorescence detection. Journal of chromatography. A. 2017 Jul; 1507(?):124-131. doi: 10.1016/j.chroma.2017.05.043. [PMID: 28554863]
  • Grzegorz R Juszczak, Artur H Swiergiel. Recreational use of D-lysergamide from the seeds of Argyreia nervosa, Ipomoea tricolor, Ipomoea violacea, and Ipomoea purpurea in Poland. Journal of psychoactive drugs. 2013 Jan; 45(1):79-93. doi: 10.1080/02791072.2013.763570. [PMID: 23662334]
  • Alexander Paulke, Christian Kremer, Cora Wunder, Stefan W Toennes. Analysis of lysergic acid amide in human serum and urine after ingestion of Argyreia nervosa seeds. Analytical and bioanalytical chemistry. 2012 Aug; 404(2):531-8. doi: 10.1007/s00216-012-6121-5. [PMID: 22695498]
  • Helene Bendstrup Klinke, Irene Breum Müller, Steffen Steffenrud, Rasmus Dahl-Sørensen. Two cases of lysergamide intoxication by ingestion of seeds from Hawaiian Baby Woodrose. Forensic science international. 2010 Apr; 197(1-3):e1-5. doi: 10.1016/j.forsciint.2009.11.017. [PMID: 20018470]
  • J W Oliver, L K Abney, J R Strickland, R D Linnabary. Vasoconstriction in bovine vasculature induced by the tall fescue alkaloid lysergamide. Journal of animal science. 1993 Oct; 71(10):2708-13. doi: 10.2527/1993.71102708x. [PMID: 7901191]
  • R J Petroski, R G Powell, K Clay. Alkaloids of Stipa robusta (sleepygrass) infected with an Acremonium endophyte. Natural toxins. 1992; 1(2):84-8. doi: 10.1002/nt.2620010205. [PMID: 1344912]
  • D V SANKAR, H H BROER, N CATES, D B SANKAR. STUDIES ON BIOGENIC AMINES AND PSYCHOACTIVE DRUG ACTIONS, WITH SPECIAL REFERENCE TO LYSERGIC ACID DIETHYL AMIDE. Transactions of the New York Academy of Sciences. 1964 Jan; 26(?):369-76. doi: 10.1111/j.2164-0947.1964.tb01258.x. [PMID: 14170548]