hyperin (BioDeep_00000270337)

PANOMIX_OTCML-2023 natural product

代谢物信息卡片

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-4-chromenone

化学式: C21H20O12 (464.0955)
中文名称: 金丝桃苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1(cc(c2c(c1)oc(c(c2=O)O[C@H]1[C@H]([C@@H]([C@H]([C@H](O1)CO)O)O)O)c1ccc(c(c1)O)O)O)O
InChI: InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1

描述信息

Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis[1][2].
Hyperoside is a NF-κB inhibitor, found from Hypericum monogynum. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis[1][2].

同义名列表

37 个代谢物同义名

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-4-chromenone; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-chromone; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(beta-D-galactopyranosyloxy)-5,7-dihydroxy-; 2-(3,4-Dihydroxyphenyl)-3-(beta-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; Quercetin 3-O-beta-D-galactopyranoside; Quercetin 3-beta-D-galactopyranoside; Quercetin-3-O-galactoside;p Hyperin; Quercetin 3-D-galactoside; quercetin-3-O-galactoside; Quercetin 3-galactoside; Quercetin-3-galactoside; EINECS 207-580-6; MEGxp0_000392; Hyperin (8CI); MLS000759538; ACon1_000623; SMR000466394; 83388_FLUKA; AIDS-026341; Hyperozide; Hyperoside; AIDS026341; NSC 407304; Hyperosid; Hyperasid; 482-36-0; hyperin; C10073; 2- (3,4-Dihydroxyphenyl) -3- (beta-D-galactopyranosyloxy) -5,7-dihydroxy-4H-1-benzopyran-4-one; Quercetin 3-beta-galactopyranoside; Quercetin 3-O-beta-D-galactoside; Quercetin-3-beta-galactoside; quercetin 3-O-galactoside; Hyperin

数据库引用编号

12 个数据库交叉引用编号

ChEBI: CHEBI:67486
PubChem: 5281643
Metlin: METLIN50457
ChEMBL: CHEMBL251254
KNApSAcK: C00005372
CAS: 482-36-0
Flavonoid: FL5FACGA0001
medchemexpress: HY-N0452
KEGG: C10073
PubChem: 12259
KNApSAcK: 67486
LOTUS: LTS0271227

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

626 个相关的物种来源信息

455045 - Abelmoschus esculentus: 10.1007/BF00600851
183220 - Abelmoschus manihot: 10.1093/CHROMSCI/47.3.206
183220 - Abelmoschus manihot (L)Medic.: -
1469224 - Acacia latifolia: 10.1021/NP50047A040
281911 - Acaena magellanica: 10.1211/0022357021779014
185140 - Acanthospermum australe: 10.1248/CPB.35.1234
171204 - Acer barbinerve: 10.1007/S10600-011-0016-0
290845 - Acer pictum: 10.1177/1934578X1501000817
1028379 - Achillea santolina: 10.1007/BF02234939
301866 - Achillea tenuifolia: 10.1007/BF02234939
282769 - Achillea teretifolia: 10.1007/BF02234939
240005 - Achyranthes aspera: 10.1007/PL00010306
451080 - Adiantum malesianum:
240009 - Aerva javanica: 10.1016/0031-9422(90)85464-Q
290911 - Aesculus chinensis: 10.1248/CPB.47.1515
49175 - Agarista salicifolia: 10.1016/J.CHROMA.2007.03.038
2773062 - Ageratina areolaris: 10.1021/NP50043A039
2773069 - Ageratina havanensis: 10.1021/NP50048A063
57912 - Agrimonia Eupatoria: -
74656 - Agrimonia pilosa Ledeb.: -
316697 - Alchornea cordifolia: 10.1002/PTR.2650040508
1174972 - Allium rotundum: 10.1007/S10600-009-9246-9
109061 - Alnus hirsuta: 10.3724/SP.J.1009.2012.00084
117272 - Amaranthus cruentus: 10.1007/BF02323285
32219 - Amelanchier alnifolia: 10.1007/BF00577214
35968 - Amelanchier bartramiana: 10.1007/BF00577214
52529 - Amelanchier humilis: 10.1007/BF00577214
52536 - Amelanchier sanguinea: 10.1007/BF00577214
1143213 - Amelanchier spicata: 10.1007/BF00577214
1105347 - Anacardium humile: 10.3390/MOLECULES15107153
357850 - Angelica keiskei: 10.1002/HLCA.201500519
508206 - Annona crassiflora: 10.1016/S0031-9422(00)00227-2
1043057 - Anthyllis henoniana: 10.1016/0031-9422(88)80698-8
365727 - Anthyllis lagascana: 10.1016/0031-9422(88)80698-8
4045 - Apium graveolens: 10.1016/S0031-9422(00)84026-1
13339 - Apocynum cannabinum:
377125 - Apocynum venetum:
377125 - Apocynum venetum L.: -
143365 - Arctostaphylos columbiana: 10.1002/JPS.2600551210
89200 - Arctostaphylos patula: 10.1002/JPS.2600551210
84009 - Arctostaphylos uva-ursi: 10.1055/S-2006-961707
85884 - Argania spinosa: 10.1080/12538078.2000.10515843
436192 - Arnica angustifolia:
436195 - Arnica chamissonis: 10.1055/S-2006-959503
436197 - Arnica fulgens: 10.1016/0305-1978(88)90085-3
436205 - Arnica lonchophylla: 10.1016/0305-1978(88)90085-3
1165903 - Arnica louiseana: 10.1016/0305-1978(88)90085-3
436211 - Arnica rydbergii: 10.1016/0305-1978(88)90085-3
436213 - Arnica sororia: 10.1016/0305-1978(88)90085-3
661339 - Aronia melanocarpa: 10.1021/JF020728U
2651882 - Artabotrys blumei: 10.1055/S-2006-957860
225833 - Artabotrys hexapetalus: 10.1055/S-2006-957860
1227615 - Artemisia alba: 10.1021/NP50052A045
35608 - Artemisia Annua L.: -
265783 - Artemisia capillaris: 10.1016/S0968-0896(00)00225-X
265783 - Artemisia capillaris Thunb.: -
72341 - Artemisia dracunculus: 10.1007/BF00563466
401925 - Artemisia palustris: 10.1007/BF00713338
72351 - Artemisia scoparia Waldst.et Kit.: -
4220 - Artemisia vulgaris: 10.1021/JF9801264
32220 - Aruncus dioicus: 10.1016/0305-1978(85)90089-4
1193810 - Asanthus solidaginifolius: 10.1021/NP50045A042
1193812 - Asanthus thyrsiflorus: 10.1021/NP50045A042
28498 - Asarum canadense: 10.1016/S0031-9422(00)00216-8
130721 - Ascarina lucida: 10.1021/NP50022A009
52823 - Asclepias curassavica: 10.1016/0031-9422(95)00511-0
155124 - Aspalathus linearis: 10.1021/JF0347721
4686 - Asparagus officinalis: 10.1201/B15147-10
73976 - Asteriscus graveolens: 10.1021/NP50076A027
657396 - Astilbe biternata: 10.1016/0305-1978(85)90089-4
268493 - Astilbe chinensis: 10.1016/0305-1978(85)90089-4
657406 - Astilbe rubra: 10.1016/0305-1978(85)90089-4
657408 - Astilbe thunbergii: 10.1016/0305-1978(85)90089-4
1197409 - Astragalus arguricus: 10.1007/BF00574227
1264805 - Astragalus brachycarpus: 10.1007/BF00564977
339481 - Astragalus coluteocarpus: 10.1007/BF00600854
2749469 - Astragalus eximius: 10.1007/BF00629813
1197414 - Astragalus goktschaicus: 10.1007/BF00574227
1906524 - Astragalus lagurus: 10.1007/BF00580090
2582817 - Astragalus levieri: 10.1007/BF00575724
2014702 - Astragalus macropterus: 10.1007/BF00579838
1091133 - Astragalus onobrychis: 10.1007/BF00574227
144147 - Astragalus robustus: 10.1007/BF00600855
1197423 - Astragalus sevangensis:
1460069 - Astragalus wagneri: 10.1007/BF00597867
72900 - Baccharis dracunculifolia: 10.1248/CPB.49.1388
258147 - Berberis canadensis: 10.1007/BF00579837
1433312 - Berberis heteropoda: 10.1007/BF00579837
1112794 - Berberis integerrima: 10.1007/BF00579837
211974 - Berberis koreana: 10.1007/BF00579837
258201 - Berberis sieboldii: 10.1007/BF00579837
258209 - Berberis vulgaris: 10.1007/BF00579837
29762 - Bergenia crassifolia: 10.1016/0305-1978(86)90088-8
2029222 - Berlandiera texana: 10.1021/NP50040A031
216991 - Betula humilis:
3505 - Betula pendula:
38787 - Betula pubescens:
120713 - Brainea insignis: 10.1248/CPB.58.868
1193818 - Brickelliastrum fendleri: 10.1021/NP50037A030
300214 - Bursera graveolens: 10.3987/COM-03-9822
4270 - Byrsonima crassifolia:
1202986 - Calligonum leucocladum: 10.1007/BF00571239
13385 - Calluna vulgaris:
516719 - Calycera crassifolia: 10.1139/B95-209
4443 - Camellia japonica: 10.1271/BBB.60112
4442 - Camellia sinensis:
1238577 - Campanula kemulariae:
239408 - Campanula kolenatiana:
239420 - Campanula raddeana:
16922 - Camptotheca acuminata: 10.1055/S-2004-835854
300208 - Canarium album: 10.1248/CPB.38.2201
626692 - Caragana spinosa: 10.1007/S10600-012-0124-5
379215 - Carpobrotus edulis: 10.1016/S0378-8741(01)00197-0
121073 - Cassytha filiformis: 10.1021/NP070564H
123405 - Catha edulis: 10.1021/NP50043A032
36622 - Chaenomeles sinensis:
140996 - Chamaebatia foliolosa: 10.1016/S0031-9422(00)81860-9
228520 - Cheniella glauca: 10.1016/J.BMCL.2015.05.089
93815 - Chimaphila umbellata:
75963 - Chondrilla juncea: 10.1515/ZNC-1993-5-603
13427 - Cichorium intybus:
337469 - Cinnamomum philippinense:
165299 - Cissus discolor: 10.1248/CPB.57.1089
289665 - Cissus verticillata: 10.1248/CPB.57.1089
335179 - Cistus laurifolius: 10.1515/ZNC-1991-1-207
151222 - Climacoptera lanata: 10.1023/B:CONC.0000025476.80448.69
60118 - Cornus controversa: 10.1016/S0031-9422(99)00502-6
4283 - Cornus florida: 10.2307/2996347
4285 - Cornus mas: 10.1016/J.FOODCHEM.2009.07.063
459758 - Cosmos sulphureus: 10.1002/MRC.2516
36607 - Cotoneaster: LTS0271227
1851000 - Cotoneaster orbicularis: 10.1016/S0031-9422(99)00598-1
1851000 - Cotoneaster orbicularis: LTS0271227
282208 - Cotula cinerea: 10.1021/NP50051A037
189211 - Crassocephalum crepidioides: 10.1248/BPB.28.19
298648 - Crataegus curvisepala: 10.1007/BF00568359
2720242 - Crataegus laciniata: 10.1021/NP50044A034
298643 - Crataegus laevigata:
140997 - Crataegus monogyna:
510734 - Crataegus orientalis: 10.1021/NP50044A034
510735 - Crataegus pinnatifida:
510735 - Crataegus pinnatifida Bge.: -
510735 - Crataegus pinnatifida Bge. var.major N.E.Br.: -
510738 - Crataegus rhipidophylla:
416296 - Crataegus sanguinea: 10.1007/BF02323285
416302 - Crataegus viridis: 10.3797/SCIPHARM.2006.74.203
170354 - Crossopteryx febrifuga: 10.1055/S-2006-962425
136114 - Cryptocarya alba: 10.1515/ZNC-1995-11-1223
1345247 - Cryptocarya moschata: 10.1590/S0100-40422010000200017
35942 - Cuphea wrightii: 10.1016/S0305-1978(02)00159-X
267555 - Cuscuta australis R. Br: -
132261 - Cuscuta campestris: 10.1016/S0305-1978(97)00015-X
267557 - Cuscuta chinensis:
267557 - Cuscuta chinensis Lam.: -
41803 - Cuscuta europaea: 10.1016/S0305-1978(97)00015-X
35886 - Cuscuta gronovii: 10.1016/S0305-1978(97)00015-X
184476 - Cuscuta lupuliformis: 10.1016/S0305-1978(97)00015-X
130754 - Cuscuta odorata: 10.1016/S0305-1978(97)00015-X
192827 - Cuscuta pedicellata: 10.1016/S0305-1978(97)00015-X
112407 - Cuscuta pentagona: 10.1016/S0305-1978(97)00015-X
132262 - Cuscuta platyloba:
4129 - Cuscuta reflexa:
36609 - Cydonia:
228707 - Cynanchum boudieri: 10.1002/JCCS.199100067
32239 - Dasiphora fruticosa: 10.1007/BF00598597
46246 - Delphinium: 10.1007/BF00563636
1048876 - Dendroviguiera eriophora: 10.1016/0305-1978(88)90035-X
1048877 - Dendroviguiera insignis: 10.1016/0305-1978(88)90035-X
1048873 - Dendroviguiera sphaerocephala: 10.1016/0305-1978(88)90035-X
1184229 - Dicoma tomentosa: 10.4314/GJPAS.V7I2.16244
4362 - Dionaea muscipula: 10.1055/S-2006-957824
35874 - Dioscorea bulbifera:
35925 - Diospyros kaki:
1217220 - Diplusodon orbicularis: 10.1016/0305-1978(94)90120-1
173410 - Drosera madagascariensis: 10.1078/0944-7113-00031
57948 - Dryas octopetala: 10.1021/NP50035A009
754878 - Ebenus sibthorpii: 10.1016/0031-9422(88)80698-8
50304 - Eleutherococcus:
2291122 - Eleutherococcus brachypus: 10.1248/CPB.59.135
230593 - Eleutherococcus divaricatus:
82096 - Eleutherococcus senticosus:
105886 - Eleutherococcus sessiliflorus:
75585 - Elliottia paniculata: 10.1248/YAKUSHI1947.94.12_1634
2595069 - Embelia schimperi: 10.1016/S0031-9422(96)00706-6
191066 - Empetrum nigrum: 10.1007/BF00598202
302009 - Ephedra campylopoda: 10.1007/BF00566073
157595 - Ephedra foeminea: 10.1007/BF00566073
33136 - Epilobium dodonaei: 10.1055/S-2004-832617
210355 - Epilobium hirsutum:
253618 - Epimedium brevicornu Maxim.: -
63351 - Epimedium koreanum Nakai: -
153729 - Epimedium pubescens: 10.1021/NP50071A030
253616 - Epimedium sagittatum: 10.1016/J.PHYTOCHEM.2007.05.035
253611 - Epimedium wushanense: 10.1016/0031-9422(90)80206-V
270432 - Erica cinerea: 10.1016/0031-9422(92)83305-I
1465301 - Erythroxylum rufum: 10.1021/NP50018A009
1924172 - Erythroxylum suberosum: 10.1016/0031-9422(88)84102-5
2589546 - Erythroxylum ulei: 10.1021/NP50018A009
34316 - Eucalyptus camaldulensis: 10.1016/0031-9422(93)85448-Z
627158 - Eucalyptus robusta: 10.1016/0031-9422(93)85448-Z
2014562 - Eugenia selloi: 10.1016/S0031-9422(03)00437-0
2759 - Eukaryota: LTS0271227
102770 - Eupatorium cannabinum:
1046441 - Euphorbia chamaesyce: 10.1007/S10600-011-9907-3
3993 - Euphorbia esula: 10.1248/CPB.53.305
1031521 - Euphorbia franchetii: 10.1007/S10600-011-9907-3
212301 - Euphorbia humifusa: 10.1016/J.FITOTE.2010.04.012
1046468 - Euphorbia hyssopifolia: 10.1002/(SICI)1099-1573(199702)11:1<22::AID-PTR951>3.0.CO;2-3
526197 - Euphorbia lunulata: 10.3390/MOLECULES16108305
1087772 - Euphorbia nicaeensis: 10.1007/978-1-4614-0535-1_53
756629 - Euphorbia paralias: 10.1016/S0031-9422(97)00832-7
1439937 - Euphorbia soongarica: 10.1007/BF01386200
756634 - Euphorbia stepposa: 10.1007/978-1-4614-0535-1_53
241838 - Excoecaria agallocha: 10.1016/J.BMCL.2011.11.109
291466 - Fagonia latifolia: 10.1016/0305-1978(92)90060-Q
3617 - Fagopyrum esculentum: 10.1021/JF9605557
154596 - Fagopyrum megacarpum: 10.1248/CPB.54.136
76029 - Fallopia convolvulus: 10.1016/S0305-1978(99)00084-8
76031 - Fallopia dumetorum: 10.1016/S0305-1978(99)00084-8
76025 - Fallopia multiflora: 10.1055/S-2006-962703
76037 - Fallopia scandens: 10.1016/S0305-1978(99)00084-8
57917 - Filipendula ulmaria: 10.1515/ZNC-2001-9-1012
757445 - Fraxinus insularis: 10.1248/CPB.41.1649
253476 - Fuchsia andrei: 10.1002/J.1537-2197.1986.TB10902.X
253477 - Fuchsia arborescens: 10.1002/J.1537-2197.1986.TB10902.X
253478 - Fuchsia boliviana:
253480 - Fuchsia coccinea: 10.1002/J.1537-2197.1986.TB10902.X
253481 - Fuchsia colensoi: 10.1002/J.1537-2197.1986.TB10902.X
22656 - Fuchsia cyrtandroides: 10.1002/J.1537-2197.1986.TB10902.X
253482 - Fuchsia decussata: 10.1002/J.1537-2197.1986.TB10902.X
658108 - Fuchsia denticulata: 10.1002/J.1537-2197.1986.TB10902.X
253483 - Fuchsia excorticata:
253484 - Fuchsia fulgens: 10.1016/0031-9422(83)80021-1
253486 - Fuchsia hartwegii: 10.1002/J.1537-2197.1986.TB10902.X
253488 - Fuchsia inflata: 10.1002/J.1537-2197.1986.TB10902.X
253491 - Fuchsia lycioides: 10.1002/J.1537-2197.1986.TB10902.X
253492 - Fuchsia macrostigma: 10.1002/J.1537-2197.1986.TB10902.X
162012 - Fuchsia magellanica: 10.1002/J.1537-2197.1986.TB10902.X
253494 - Fuchsia microphylla: 10.1002/J.1537-2197.1986.TB10902.X
253498 - Fuchsia paniculata: 10.1002/J.1537-2197.1986.TB10902.X
1793818 - Fuchsia perscandens: 10.1002/J.1537-2197.1986.TB10902.X
253499 - Fuchsia pilaloensis: 10.1002/J.1537-2197.1986.TB10902.X
85206 - Fuchsia procumbens: 10.1002/J.1537-2197.1986.TB10902.X
253500 - Fuchsia regia: 10.1002/J.1537-2197.1986.TB10902.X
253502 - Fuchsia splendens:
13070 - Fuchsia triphylla:
29793 - Galium palustre: 10.1201/9781315120157-15
212252 - Galphimia glauca:
112833 - Galphimia gracilis:
231905 - Garcinia dulcis: 10.1016/J.PHYTOCHEM.2005.10.016
554690 - Geranium carolinianum: 10.1248/BPB.31.743
554690 - Geranium carolinianum L.: -
1659214 - Geranium platyanthum: 10.32861/JBR.66.57.61
122182 - Geranium pusillum: 10.1023/B:CONC.0000025477.18086.8B
122183 - Geranium robertianum: 10.1055/S-0032-1321052
314613 - Geranium tuberosum: 10.1002/HLCA.200800346
202327 - Geranium Wilfordii Maxim.: -
3311 - Ginkgo biloba: -
3635 - Gossypium hirsutum: 10.1007/S10600-008-9067-2
4397 - Hamamelis virginiana: 10.1007/BF02323304
147773 - Haplopappus foliosus: 10.1021/NP50021A021
452782 - Haplophyllum robustum: 10.1016/0031-9422(84)83046-0
57576 - Hedysarum alpinum: 10.1007/BF00630415
1641286 - Hedysarum inundatum: 10.1007/BF00630415
1641291 - Hedysarum neglectum: 10.1007/BF00683857
193516 - Hippophae rhamnoides:
16752 - Houttuynia cordata: 10.1248/CPB.57.1227
16752 - Houttuynia cordata Thunb.: -
3486 - Humulus lupulus:
554381 - Hydrocotyle leucocephala: 10.1016/J.PHYTOCHEM.2006.03.004
4049 - Hydrocotyle sibthorpioides: 10.1016/0031-9422(82)83079-3
1136954 - Hypericum adenotrichum: 10.3109/13880209109082884
140968 - Hypericum androsaemum:
210378 - Hypericum ascyron: 10.1007/BF00630668
282533 - Hypericum attenuatum: 10.1007/BF02323302
1321321 - Hypericum aucheri: 10.1007/BF00598599
268978 - Hypericum balearicum: 10.1055/S-2006-957796
268979 - Hypericum beanii: 10.1248/CPB.59.1250
1136959 - Hypericum bithynicum: 10.1055/S-2006-957796
1341022 - Hypericum brasiliense: 10.1016/0031-9422(95)00507-4
228412 - Hypericum canariense: 10.3987/COM-89-5087
1321326 - Hypericum caprifolium: 10.1078/094471103322331476
1321328 - Hypericum elegans: 10.1080/14786410802278327
282539 - Hypericum erectum:
268990 - Hypericum ericoides: 10.1016/0031-9422(82)83122-1
999597 - Hypericum fauriei: 10.1007/BF00598324
336625 - Hypericum glandulosum: 10.1055/S-2006-957796
268995 - Hypericum graveolens: 10.1007/BF02323302
673928 - Hypericum hirsutum:
626746 - Hypericum humifusum: 10.1055/S-2006-960798
282544 - Hypericum kamtschaticum: 10.1007/BF02323302
1136989 - Hypericum laricifolium: 10.1248/CPB.51.1439
269006 - Hypericum maculatum:
684760 - Hypericum monogynum: 10.1201/9781420023305-8
673929 - Hypericum montanum: 10.1055/S-2006-960798
1136997 - Hypericum montbretii: 10.3109/13880209109082884
1321338 - Hypericum myrianthum: 10.1078/094471103322331476
65561 - Hypericum perforatum:
1341051 - Hypericum polyanthemum: 10.1078/094471103322331476
1137013 - Hypericum pseudomaculatum: 10.1007/BF02323302
282551 - Hypericum pseudopetiolatum: 10.1007/BF02323302
269017 - Hypericum punctatum: 10.1007/BF02323302
673934 - Hypericum richeri: 10.1080/14786410802401390
282553 - Hypericum sampsonii:
1137022 - Hypericum scabrum: 10.1021/NP040024+
282556 - Hypericum sikokumontanum: 10.1016/J.PHYTOCHEM.2008.11.006
282557 - Hypericum ternum: 10.1078/094471103322331476
626749 - Hypericum tetrapterum: 10.1055/S-2006-960798
282558 - Hypericum triquetrifolium:
1053357 - Hypericum undulatum: 10.1007/BF02323302
1321359 - Hypericum venustum: 10.1016/J.FITOTE.2007.11.012
185166 - Ichthyothere terminalis: 10.1016/0031-9422(82)83123-3
211591 - Iphiona scabra: 10.1016/S0031-9422(00)81848-8
2687269 - Jacaranda decurrens: 10.1007/BF00985673
91218 - Juglans mandshurica: 10.1007/S10600-011-9895-3
51240 - Juglans regia: 10.1002/ARDP.19552880805
45902 - Kalmia latifolia: 10.1021/NP50012A008
228393 - Kalopanax septemlobus: 10.1177/1934578X1501000817
43168 - Koelreuteria paniculata: 10.1080/1028602021000049087
125586 - Koenigia alpina:
313104 - Lathyrus palustris: 10.1016/0305-1978(93)90077-5
587664 - Leonurus cardiaca: 10.1021/NP50039A028
1272976 - Leptobalanus apetalus: 10.1016/S0305-1978(01)00089-8
1072387 - Limonium aureum: 10.1007/S10600-006-0089-3
435386 - Liparophyllum lasiospermum: 10.1002/J.1537-2197.1986.TB08521.X
105884 - Lonicera japonica: 10.1017/S0890037X0003027X
47247 - Lotus corniculatus: 10.1007/S10600-009-9362-6
1006353 - Lotus ucrainicus: 10.1007/S10600-009-9362-6
260603 - Lycopus europaeus: 10.1055/S-2006-958151
49153 - Lyonia ovalifolia: 10.1248/YAKUSHI1947.79.3_403
213267 - Lysimachia fortunei:
213271 - Lysimachia heterogenea: 10.3390/MOLECULES16098076
306286 - Lysimachia mauritiana: 10.1016/S0031-9422(00)82393-6
174664 - Lysimachia thyrsiflora: 10.1016/S0305-1978(96)00086-5
191068 - Lysimachia vulgaris: 10.1016/0031-9422(88)80719-2
109849 - Macaranga tanarius: 10.1016/J.PHYTOCHEM.2009.07.020
325535 - Machilus japonica: 10.1021/NP9000653
1198337 - Maerua crassifolia: 10.21608/BFSA.1995.69669
3398 - Magnoliopsida: LTS0271227
151847 - Malpighia emarginata: 10.1271/BBB.80421
3750 - Malus domestica:
283210 - Malus pumila:
387710 - Mandevilla martiana: 10.1002/PTR.865
29780 - Mangifera indica: 10.1021/JF030218F
120598 - Manoao colensoi: 10.1021/NP50052A014
98504 - Matricaria chamomilla: 10.1007/BF02490607
3879 - Medicago sativa:
1611021 - Meehania fargesii: 10.1248/CPB.58.696
73757 - Melaleuca ericifolia: 10.1016/J.PHYTOCHEM.2007.03.010
1279044 - Melilotus messanensis: 10.1055/S-0028-1097913
28525 - Menyanthes trifoliata: 10.1007/BF00570212
696524 - Microtea debilis: 10.1021/NP970025K
76306 - Mimosa pudica: 10.1016/S0305-1978(01)00086-2
332453 - Minthostachys setosa: 10.1016/0166-3542(93)90095-Z
332455 - Minthostachys spicata: 10.1016/0305-1978(95)00039-W
1081520 - Monteverdia ilicifolia: 10.1590/S0103-50532010000200009
2054533 - Morina nepalensis: 10.1002/MRC.1034
59982 - Myrsine africana: 10.1016/S0031-9422(96)00329-9
119949 - Myrtus communis: 10.1007/BF02467181
4432 - Nelumbo nucifera:
144308 - Nierembergia hippomanica: 10.1016/0031-9422(95)00731-8
274375 - Nierembergia linariifolia: 10.1016/0031-9422(95)00731-8
59673 - Norantea guianensis: 10.1016/0031-9422(74)85149-6
28933 - Nothofagus antarctica: 10.1016/S0031-9422(96)00745-5
435376 - Nymphoides cordata: 10.1002/J.1537-2197.1986.TB08521.X
435377 - Nymphoides crenata: 10.1002/J.1537-2197.1986.TB08521.X
1775737 - Nymphoides grayana: 10.1002/J.1537-2197.1986.TB08521.X
204144 - Ocimum gratissimum: 10.1002/1099-1565(200007/08)11:4<257::AID-PCA521>3.0.CO;2-A
49556 - Oenanthe javanica:
238280 - Oenothera affinis: 10.1016/S0176-1617(11)80953-3
238283 - Oenothera canescens: 10.1002/J.1537-2197.1988.TB13465.X
482428 - Oenothera glazioviana: 10.1007/BF02234915
238286 - Oenothera havardii: 10.1002/J.1537-2197.1988.TB13465.X
690538 - Oenothera kunthiana: 10.1002/J.1537-2197.1988.TB13465.X
3951 - Oenothera odorata: 10.1111/J.1438-8677.1994.TB00414.X
3953 - Oenothera speciosa: 10.3390/MOLECULES14041456
238300 - Oenothera tetraptera: 10.1002/J.1537-2197.1988.TB13465.X
872932 - Onobrychis bobrovii: 10.1007/BF00577212
451724 - Onobrychis cornuta: 10.1007/BF00579157
1819622 - Onobrychis echidna: 10.1007/BF00579157
1641303 - Onobrychis grandis:
1641307 - Onobrychis saravschanica: 10.1007/BF00579157
367364 - Ophiorrhiza kuroiwae:
489897 - Ophiorrhiza liukiuensis:
414651 - Ormopteris gleichenioides: 10.1016/S0305-1978(98)00032-5
434452 - Ormopteris pinnata: 10.1016/S0305-1978(98)00032-5
434453 - Ormopteris riedelii: 10.1016/S0305-1978(98)00032-5
2899638 - Ornduffia albiflora: 10.1002/J.1537-2197.1986.TB08521.X
2848788 - Ornduffia parnassifolia: 10.1002/J.1537-2197.1986.TB08521.X
106693 - Paliurus spina-christi: 10.1007/BF00599276
33128 - Papaver rhoeas: 10.1055/S-2004-818956
157622 - Paronychia argentea: 10.1002/MRC.2113
157632 - Paronychia kapela: 10.1023/B:CONC.0000033945.16862.19
3435 - Persea americana: 10.1002/(SICI)1099-1573(199812)12:8<562::AID-PTR356>3.0.CO;2-6
254780 - Persicaria amphibia:
580470 - Persicaria decipiens:
430754 - Persicaria lapathifolia:
1155347 - Persicaria mitis: 10.1080/13880200600798544
452460 - Persicaria nepalensis: 10.1021/NP50051A003
668956 - Persicaria thunbergii: 10.1248/YAKUSHI1947.107.12_1001
1779205 - Phanera japonica: 10.1016/0031-9422(90)80075-R
91120 - Phedimus kamtschaticus: 10.1007/BF00567044
68554 - Phellodendron amurense: 10.1248/CPB.54.1308
23115 - Philadelphus lewisii: 10.1016/0305-1978(86)90089-X
449869 - Phlebodium decumanum: 10.1016/0305-1978(86)90025-6
128687 - Phoebe formosana: 10.1002/JCCS.199900034
337186 - Physochlaina physaloides: 10.1007/BF00633404
92917 - Picnomon acarna: 10.1021/NP50122A015
375272 - Pimenta dioica: 10.1021/NP0705615
3353 - Pinus banksiana:
101996 - Plantago coronopus: 10.1007/S10600-011-9908-2
39414 - Plantago lanceolata: 10.1007/S10600-011-9908-2
29818 - Plantago major: 10.1007/S10600-011-9908-2
33090 - Plants: -
28511 - Pogostemon Cablin (Blanco) Benth.: -
2259079 - Polygonatum orientale: 10.1007/S10600-011-0072-5
83819 - Polygonum cuspidatum Sieb. et Zucc.: -
388918 - Polygonum scabrum: 10.1007/BF00563488
281888 - Polylepis besseri: 10.1016/0305-1978(95)93663-N
281893 - Polylepis incana: 10.1016/0305-1978(95)93663-N
872808 - Polypodium virginianum: 10.1016/S0031-9422(00)98486-3
58048 - Polypodium vulgare: 10.1016/S0031-9422(00)98486-3
39358 - Prunella vulgaris: 10.1016/S1001-0742(14)60648-3
39358 - Prunella vulgaris L.: -
97307 - Prunus padus: 10.1080/14786410903230359
3760 - Prunus persica: 10.1021/JF0104681
323851 - Prunus persica var. nucipersica: 10.1021/JF0104681
418402 - Pseudostellaria heterophylla: 10.3390/MOLECULES21111538
120290 - Psidium guajava: 10.1007/S11418-010-0400-2
119188 - Pulicaria incisa: 10.1007/S10600-019-02792-7
193309 - Pyracantha coccinea: 10.1016/0031-9422(93)85108-4
93820 - Pyrola americana: 10.1248/CPB.40.2083
642526 - Pyrola calliantha: 10.4268/CJCMM20150419
642526 - Pyrola calliantha H.AndreS: -
642527 - Pyrola decorata H. Andres: -
93825 - Pyrola elliptica: 10.1016/S0031-9422(97)00878-9
642531 - Pyrola incarnata: 10.1016/0031-9422(89)80060-3
642532 - Pyrola japonica: 10.1248/CPB.52.714
13651 - Pyrola rotundifolia: 10.1248/CPB.40.2083
58334 - Quercus ilex: 10.1016/S0031-9422(00)89514-X
262616 - Quercus laurifolia: 10.1002/ARDP.19933260906
58331 - Quercus suber: 10.1002/ARDP.2503240811
3610 - Rhamnus cathartica: 10.1081/JLC-100101645
1813078 - Rhamnus disperma: 10.1016/S0031-9422(99)00262-9
1442767 - Rhodiola coccinea: 10.1007/BF00563908
176258 - Rhododendron arboreum: 10.1007/BF03048930
118365 - Rhododendron brachycarpum: 10.1007/BF02856638
257784 - Rhododendron catawbiense: 10.1021/JF00114A018
880079 - Rhododendron dauricum:
880079 - Rhododendron dauricum L.: -
344754 - Rhododendron decorum: 10.1007/S10600-009-9245-X
134444 - Rhododendron ellipticum: 10.1016/0031-9422(94)00905-9
49622 - Rhododendron ferrugineum: 10.1016/S0031-9422(98)00080-6
49605 - Rhododendron groenlandicum: 10.1007/BF00638770
321365 - Rhododendron irroratum: 10.1007/S10600-008-0028-6
184576 - Rhododendron latoucheae: 10.1016/0031-9422(94)00905-9
880082 - Rhododendron ledebourii: 10.1007/BF02329610
49626 - Rhododendron moulmainense: 10.1016/0031-9422(94)00905-9
105903 - Rhododendron mucronulatum: 10.1007/BF02329610
880084 - Rhododendron sichotense: 10.1007/BF02329610
118357 - Rhododendron simsii: 10.1016/0031-9422(93)85102-W
182159 - Rhododendron spinuliferum: 10.1007/S10600-009-9410-2
189224 - Robinsonia berteroi: 10.1002/J.1537-2197.1985.TB08343.X
409886 - Robinsonia evenia: 10.1002/J.1537-2197.1985.TB08343.X
409887 - Robinsonia gayana: 10.1002/J.1537-2197.1985.TB08343.X
409889 - Robinsonia masafuerae: 10.1002/J.1537-2197.1985.TB08343.X
409890 - Robinsonia thurifera: 10.1002/J.1537-2197.1985.TB08343.X
1277869 - Rodgersia sambucifolia: 10.1016/0305-1978(85)90089-4
462493 - Roldana lineolata: 10.1016/J.FITOTE.2007.07.002
1707471 - Roldana lobata: 10.1515/ZNB-2008-0317
3764 - Rosa: 10.1002/PCA.2800040607
267229 - Rosa agrestis: 10.1080/14786410903075507
74635 - Rosa canina: 10.1016/0031-9422(94)00784-Q
237596 - Rosa davurica: 10.1248/CPB.37.2232
74648 - Rosa lucieae: 10.1248/CPB.40.2080
74647 - Rosa multiflora: 10.1248/CPB.40.2080
74645 - Rosa rugosa: 10.1007/S10600-006-0267-3
3745 - Rosaceae: LTS0271227
1903424 - Rotala rosea: 10.1021/NP50018A004
29802 - Rubia tinctorum: 10.1007/978-3-540-71095-0_9011
23216 - Rubus: 10.1002/JSFA.1885
616954 - Rubus amabilis: 10.1055/S-2001-11996
32247 - Rubus idaeus: 10.1021/JF00035A025
75091 - Rubus saxatilis: 10.1007/S10600-005-0148-1
41241 - Rumex acetosa: 10.1248/CPB.38.2277
75708 - Salix chaenomeloides: 10.1021/NP50077A042
71983 - Sanicula graveolens: 10.1002/(SICI)1099-1573(199908/09)13:5<422::AID-PTR462>3.0.CO;2-M
345810 - Sarcomphalus mistol: 10.1016/0305-1978(93)90066-Z
50001 - Sarracenia alata: 10.1016/0305-1978(77)90039-4
4359 - Sarracenia flava: 10.1016/0305-1978(77)90039-4
332461 - Sarracenia jonesii: 10.1016/0305-1978(77)90039-4
50002 - Sarracenia leucophylla: 10.1016/0305-1978(77)90039-4
50003 - Sarracenia minor: 10.1016/0305-1978(77)90039-4
50004 - Sarracenia oreophila: 10.1016/0305-1978(77)90039-4
50005 - Sarracenia psittacina: 10.1016/0305-1978(77)90039-4
45176 - Sarracenia purpurea:
50006 - Sarracenia rubra: 10.1016/0305-1978(77)90039-4
54806 - Saururus chinensis (Lour.) Baill.: -
29769 - Saxifraga cernua: 10.1016/0305-1978(84)90068-1
102738 - Saxifraga tricuspidata: 10.1016/0305-1978(84)90068-1
691236 - Scandosorbus intermedia: 10.1007/S10600-009-9409-8
4278 - Securidaca diversifolia: 10.1016/S0031-9422(00)80695-0
1538674 - Sempervivum ruthenicum: 10.1007/BF00565316
138017 - Senegalia catechu: 10.4268/CJCMM20101114
875646 - Senegalia polyacantha: 10.4268/CJCMM20101114
2945705 - Sideroxylon spinosum: 10.1080/12538078.2000.10515843
53588 - Silphium perfoliatum: 10.1016/S0031-9422(02)00133-4
170185 - Sinoadina racemosa:
489401 - Smyrnium creticum: 10.1021/NP50022A030
109975 - Solanum americanum: 10.1016/S0031-9422(00)97839-7
397274 - Solanum cernuum: 10.1016/J.TETLET.2011.09.060
329779 - Solanum incanum: 10.1007/BF01870610
4112 - Solanum nigrum: 10.1016/S0031-9422(00)97839-7
4112 - Solanum Nigrum Linn.: -
45838 - Solanum ptychanthum: 10.1016/S0031-9422(00)97839-7
462879 - Solidago virgaurea: 10.1016/S0031-9422(00)85038-4
50193 - Sonchus asper: 10.1016/0305-1978(93)90062-V
171567 - Sophora tetraptera: 10.1016/S0031-9422(00)85741-6
36599 - Sorbus aucuparia: 10.1007/S002170100328
691244 - Sorbus tianschanica: 10.1007/BF00633293
173898 - Sphaerostephanos penniger: 10.1016/0305-1978(93)90081-2
3562 - Spinacia oleracea: 10.1007/BF00630375
409510 - Spiraea formosana:
409519 - Spiraea salicifolia: 10.1007/S10600-018-2530-9
558484 - Stevia microchaeta: 10.1021/NP50039A036
558490 - Stevia nepetifolia: 10.1021/NP50033A038
558494 - Stevia origanoides: 10.1021/NP50039A036
558511 - Stevia serrata: 10.1021/NP50041A039
35493 - Streptophyta: LTS0271227
99302 - Strychnos spinosa: 10.1021/NP058062W
299721 - Sulla coronaria: 10.1021/JF2014759
1642404 - Symphyotrichum eatonii: 10.1016/0305-1978(88)90086-5
53928 - Tachigali paniculata: 10.1021/NP0200764
2918413 - Taxillus kaempferi: 10.1248/YAKUSHI1947.116.2_148
99812 - Taxodium mucronatum: 10.1016/0031-9422(94)00784-Q
313942 - Tessaria integrifolia: 10.3136/FSTR.6.106
2914000 - Torminalis glaberrima: 10.1016/J.PHYTOL.2011.02.005
690252 - Toxicodendron wallichii: 10.1021/NP50045A034
58023 - Tracheophyta: LTS0271227
74504 - Trifolium ambiguum: 10.1007/BF00567881
361560 - Trifolium arvense: 10.1007/BF00567719
361561 - Trifolium aureum: 10.1007/BF00579982
74522 - Trifolium montanum: 10.1007/BF00573562
57577 - Trifolium pratense:
3899 - Trifolium repens: 10.1016/S0031-9422(00)00124-2
50169 - Tripodanthus acutifolius: 10.1016/J.JEP.2010.05.015
118778 - Tussilago farfara L.: -
714512 - Uncaria hirsuta Havil.: -
43575 - Uncaria rhynchophylla: 10.1248/CPB.30.4046
714514 - Uncaria sessilifructus Roxb.: -
655181 - Uncaria sinensis: 10.1142/S0192415X01000198
122557 - Urospermum dalechampii: 10.1016/0305-1978(93)90061-U
268113 - Urospermum picroides:
69266 - Vaccinium corymbosum:
13750 - Vaccinium macrocarpon:
180763 - Vaccinium myrtillus: 10.1111/J.1365-2621.1987.TB14056.X
190544 - Vaccinium ovalifolium: 10.1007/S10600-008-0029-5
516948 - Vaccinium oxycoccos: 10.1007/BF00566809
180772 - Vaccinium vitis-idaea: 10.1021/JF0623687
138046 - Vachellia tortilis: 10.4000/BOOKS.IRDEDITIONS.5257
32250 - Vauquelinia corymbosa: 10.3390/MOLECULES200815330
945253 - Verbesina encelioides: 10.1016/0031-9422(80)85040-0
97415 - Viola arvensis: 10.1007/S11094-005-0104-1
33090 - Viridiplantae: LTS0271227
1007890 - Visnea mocanera: 10.1021/JF9505335
3605 - Vitis aestivalis:
226012 - Vitis cinerea: 10.1016/0305-1978(87)90085-8
29760 - Vitis vinifera:
328401 - Zanthoxylum bungeanum:
354529 - Zanthoxylum piperitum: 10.1271/BBB.50669
326968 - Ziziphus jujuba: 10.1021/JF302848U
264981 - Ziziphus spina-christi:
33090 - 三白草: -
74656 - 仙鹤草: -
58880 - 余甘子: -
33090 - 关黄柏: -
33090 - 凤眼草: -
33090 - 夏枯草: -
33090 - 山楂叶: -
33090 - 布渣叶: -
33090 - 广枣: -
33090 - 广藿香: -
33090 - 拳参: -
33090 - 木棉花: -
33090 - 杜仲叶: -
33090 - 枇杷叶: -
33090 - 枸骨叶: -
33090 - 柴胡: -
33090 - 柿蒂: -
33090 - 款冬花: -
33090 - 沙苑子: -
33090 - 泽漆: -
33090 - 淫羊藿: -
33090 - 满山红: -
33090 - 牛膝: -
33090 - 猫眼草: -
33090 - 益母草: -
33090 - 罗布麻叶: -
33090 - 老鹳草: -
4047 - 芫荽: -
33090 - 花椒: -
33090 - 苦丁茶: -
33090 - 草果: -
33090 - 荷叶: -
33090 - 莲子心: -
33090 - 莲房: -
33090 - 菟丝子: -
33090 - 萹蓄: -
33090 - 虎杖: -
33090 - 覆盆子: -
33090 - 连翘: -
569774 - 金线莲: -
33090 - 金钱草: -
33090 - 金银花: -
33090 - 钩藤: -
33090 - 青果: -
496566 - 青蒿: -
33090 - 鬼箭羽: -
33090 - 鬼针草: -
33090 - 鱼腥草: -
33090 - 鸦胆子: -
33090 - 鹿衔草: -
33090 - 黄柏: -
33090 - 黄药子: -
33090 - 鼠曲草: -
33090 - 龙葵: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Bingqing Chi, Meng Zhang, Luping Sun, Hongyan Liu, Zhenhua Tian. Study on the hypotensive effect and mechanism of hawthorn (Crataegus pinnatifida) fruits and hyperoside in spontaneously hypertensive rats. Food & function. 2024 May; 15(10):5627-5640. doi: 10.1039/d3fo02641h. [PMID: 38722076]
Daijin Li, Jie Chang, Yujue Wang, Xiaoye Du, Jing Xu, Jingang Cui, Teng Zhang, Yu Chen. Hyperoside mitigates photoreceptor degeneration in part by targeting cGAS and suppressing DNA-induced microglial activation. Acta neuropathologica communications. 2024 May; 12(1):76. doi: 10.1186/s40478-024-01793-0. [PMID: 38755736]
Jia Xia, Yan Wan, Jiao-Jiao Wu, Yu Yang, Jin-Feng Xu, Li Zhang, Dong Liu, Lu Chen, Fei Tang, Hui Ao, Cheng Peng. Therapeutic potential of dietary flavonoid hyperoside against non-communicable diseases: targeting underlying properties of diseases. Critical reviews in food science and nutrition. 2024; 64(5):1340-1370. doi: 10.1080/10408398.2022.2115457. [PMID: 36073729]
Lei Shi, Chenchen Jiang, Hanghang Xu, Jiangping Wu, Jiajun Lu, Yuxiang He, Xiuyun Yin, Zhuo Chen, Di Cao, Xuebin Shen, Xuefeng Hou, Jun Han. Hyperoside ameliorates cerebral ischaemic-reperfusion injury by opening the TRPV4 channel in vivo through the IP3-PKC signalling pathway. Pharmaceutical biology. 2023 Dec; 61(1):1000-1012. doi: 10.1080/13880209.2023.2228379. [PMID: 37410551]
Qigang Fan, Ruifen He, Yi Li, Pu Gao, Runchun Huang, Rong Li, Jiayu Zhang, Hongli Li, Xiaolei Liang. Studying the effect of hyperoside on recovery from cyclophosphamide induced oligoasthenozoospermia. Systems biology in reproductive medicine. 2023 Oct; 69(5):333-346. doi: 10.1080/19396368.2023.2241600. [PMID: 37578152]
Daijin Li, Jing Xu, Jie Chang, Yujue Wang, Xiaoye Du, Hanhan Wu, Jingang Cui, Peiwei Wang, Teng Zhang, Yu Chen. Hyperoside protects against oxidative stress-mediated photoreceptor degeneration: therapeutic potentials for photoreceptor degenerative diseases. Journal of translational medicine. 2023 08; 21(1):569. doi: 10.1186/s12967-023-04459-y. [PMID: 37620913]
Yuwen Shi, Mengcheng Jiang, Yuhang Zhang, Yuanyuan Diao, Na Li, Weipeng Liu, Zhidong Qiu, Ye Qiu, Ailing Jia. Hyperoside Nanomicelles Alleviate Atherosclerosis by Modulating the Lipid Profile and Intestinal Flora Structure in High-Fat-Diet-Fed Apolipoprotein-E-Deficient Mice. Molecules (Basel, Switzerland). 2023 Jun; 28(13):. doi: 10.3390/molecules28135088. [PMID: 37446750]
Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
Hongqiang An, Chu Chu, Zhen Zhang, Yunhong Zhang, Ran Wei, Bin Wang, Ke Xu, Lihua Li, Yonglin Liu, Gang Li, Xia Li. Hyperoside alleviates postmenopausal osteoporosis via regulating miR-19a-5p/IL-17A axis. American journal of reproductive immunology (New York, N.Y. : 1989). 2023 May; ?(?):e13709. doi: 10.1111/aji.13709. [PMID: 37157916]
Xinyue Zhang, Dan Li, Kexin Wang, Jiao Xie, Yaojie Liu, Tianxin Wang, Suwen Liu, Qun Huang, Qingbin Guo, Hao Wang. Hyperoside inhibits pancreatic lipase activity in vitro and reduces fat accumulation in vivo. Food & function. 2023 May; ?(?):. doi: 10.1039/d2fo03219h. [PMID: 37128768]
Deniz Yuzbasioglu, Ummugulsum Kubra Dilek, Esra Erikel, Fatma Unal. Antigenotoxic effect of hyperoside against Mitomycin C and hydrogen peroxide-induced genotoxic damage on human lymphocytes. Toxicology in vitro : an international journal published in association with BIBRA. 2023 May; 90(?):105604. doi: 10.1016/j.tiv.2023.105604. [PMID: 37137419]
Siyao Cheng, Xintao Ni, Yanjing Yao, Yunxia Sun, Xiaofeng Yu, Daozong Xia, Zhenggang Yang, Miaofen G Hu, Xiaoli Hou. Hyperoside prevents high-fat diet-induced obesity by increasing white fat browning and lipophagy via CDK6-TFEB pathway. Journal of ethnopharmacology. 2023 Feb; 307(?):116259. doi: 10.1016/j.jep.2023.116259. [PMID: 36781055]
Yanli Song, Dongjie He, Shaoqi Shi, Tianwei Cui, Hui Zhang, Xianmin Zhao, Tingting Ni, Huidongzi Xiao, Aiwu Wei. Hyperoside exerts protective effects against anticardiolipin antibody-induced recurrent pregnancy loss in vivo and in vitro. Human & experimental toxicology. 2023 Jan; 42(?):9603271231163476. doi: 10.1177/09603271231163476. [PMID: 37042322]
Rui Song, Yunrui Xia, Zhe Zhao, Xing Yang, Nanyi Zhang. Effects of plant growth regulators on the contents of rutin, hyperoside and quercetin in Hypericum attenuatum Choisy. PloS one. 2023; 18(5):e0285134. doi: 10.1371/journal.pone.0285134. [PMID: 37134044]
Jingyin Mai, Qingqing He, Yuting Liu, Yuting Hou. Hyperoside Attenuates Sepsis-Induced Acute Lung Injury (ALI) through Autophagy Regulation and Inflammation Suppression. Mediators of inflammation. 2023; 2023(?):1257615. doi: 10.1155/2023/1257615. [PMID: 37545738]
Xing-Jie Xu, Tao Pan, Hui-Jie Fan, Xu Wang, Jie-Zhong Yu, Hai-Fei Zhang, Bao-Guo Xiao, Zhen-Yu Li, Bo Zhang, Cun-Gen Ma, Zhi Chai. Neuroprotective effect of hyperoside in MPP+/MPTP -induced dopaminergic neurodegeneration. Metabolic brain disease. 2022 Dec; ?(?):. doi: 10.1007/s11011-022-01153-8. [PMID: 36576692]
Ya-Ting Jiao, Wen-Shu Zhang, Shan-Shan Pan, Ming-Jie Xie. [Multi-omics analysis of regulating effects of hyperoside on lipid metabolism in high-fat diet mice]. Sheng li xue bao : [Acta physiologica Sinica]. 2022 Dec; 74(6):970-978. doi: ". [PMID: 36594385]
Jun Zhu, Min Zhang, Xiong-Li Liu, Zhi-Gang Yin, Xiao-Xue Han, Hui-Juan Wang, Ying Zhou. Hyperoside suppresses osteoclasts differentiation and function through downregulating TRAF6/p38 MAPK signaling pathway. Journal of Asian natural products research. 2022 Dec; 24(12):1157-1168. doi: 10.1080/10286020.2022.2056028. [PMID: 35435096]
Aoqi Song, Zhenghua Wu, Wenjuan Zhao, Wenqing Shi, Ru Cheng, Jingjing Jiang, Zhuojun Ni, Han Qu, Xijier Qiaolongbatu, Guorong Fan, Yuefen Lou. The Role and Mechanism of Hyperoside against Depression-like Behavior in Mice via the NLRP1 Inflammasome. Medicina (Kaunas, Lithuania). 2022 Nov; 58(12):. doi: 10.3390/medicina58121749. [PMID: 36556951]
Guo-Si Li, Fu-Cheng Zhu, Pei-Pei Wei, Fang-Li Gu, Qi-Ling Xu, Meng-Hua Ma. Development of an Escherichia coli whole cell biocatalyst for the production of hyperoside. Biotechnology letters. 2022 Sep; 44(9):1073-1080. doi: 10.1007/s10529-022-03285-4. [PMID: 35920962]
Tian Xie, Jun Yuan, Ling Mei, Ping Li, Ruijie Pan. Hyperoside ameliorates TNF‑α‑induced inflammation, ECM degradation and ER stress‑mediated apoptosis via the SIRT1/NF‑κB and Nrf2/ARE signaling pathways in vitro. Molecular medicine reports. 2022 Aug; 26(2):. doi: 10.3892/mmr.2022.12776. [PMID: 35730622]
Xiao Chen, Ademola C Famurewa, Jian Tang, Oladipupo Odunayo Olatunde, Opeyemi Joshua Olatunji. Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress via suppressing TNF-α/NF-κB/caspase-3 signaling in type 2 diabetes rats. Nutritional neuroscience. 2022 Aug; 25(8):1774-1784. doi: 10.1080/1028415x.2021.1901047. [PMID: 33722183]
Qi Wang, Hao-Cheng Wei, Sheng-Jun Zhou, Ying Li, Ting-Ting Zheng, Chang-Zheng Zhou, Xin-Huan Wan. Hyperoside: A review on its sources, biological activities, and molecular mechanisms. Phytotherapy research : PTR. 2022 Jul; 36(7):2779-2802. doi: 10.1002/ptr.7478. [PMID: 35561084]
Yu Yan Xie, Yun Wei Lu, Gu Ran Yu. The protective effects of hyperoside on Ang II-mediated apoptosis of bEnd.3 cells and injury of blood-brain barrier model in vitro. BMC complementary medicine and therapies. 2022 Jun; 22(1):157. doi: 10.1186/s12906-022-03635-9. [PMID: 35698113]
Y Zhu, T Wang, N Dai, M Deng, H Liu, X Tong, L Li. [Hyperoside protects mouse spermatocytes GC-2 cells from oxidative damage by activating the Keap1/Nrf2/HO-1 pathway]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 2022 May; 42(5):673-680. doi: 10.12122/j.issn.1673-4254.2022.05.07. [PMID: 35673910]
Sijin Xu, Shuaipeng Chen, Wenxin Xia, Hong Sui, Xueyan Fu. Hyperoside: A Review of Its Structure, Synthesis, Pharmacology, Pharmacokinetics and Toxicity. Molecules (Basel, Switzerland). 2022 May; 27(9):. doi: 10.3390/molecules27093009. [PMID: 35566359]
Xiaolei Yang, Guanghao Zhu, Ying Zhang, Xubo Wu, Bei Liu, Ye Liu, Qing Yang, Wandi Du, Jingru Liang, Jiarong Hu, Ping Yang, Guangbo Ge, Weimin Cai, Guo Ma. Inhibition of Human UDP-Glucuronosyltransferases1A1-Mediated Bilirubin Glucuronidation by the Popular Flavonoids Baicalein, Baicalin, and Hyperoside Is Responsible for Herb (Shuang-Huang-Lian)-Induced Jaundice. Drug metabolism and disposition: the biological fate of chemicals. 2022 05; 50(5):552-565. doi: 10.1124/dmd.121.000714. [PMID: 35241486]
Siqi Fan, Haida Pan, Jiaxing Huang, Zhiqiang Lei, Jinfu Liu. Hyperoside exerts osteoprotective effect on dexamethasone-induced osteoblasts by targeting NADPH Oxidase 4 (NOX4) to inhibit the reactive oxygen species (ROS) accumulation and activate c-Jun N-terminal kinase (JNK) pathway. Bioengineered. 2022 04; 13(4):8657-8666. doi: 10.1080/21655979.2022.2054499. [PMID: 35331079]
Esra Saçıcı, Erdem Yesilada. Development of new and validated HPTLC methods for the qualitative and quantitative analysis of hyperforin, hypericin and hyperoside contents in Hypericum species. Phytochemical analysis : PCA. 2022 Apr; 33(3):355-364. doi: 10.1002/pca.3093. [PMID: 34734668]
Songul Karakaya, Ipek Suntar, Bilge Aydin, Benan Dursunoglu, Sefa Gözcu, Onur Senol, Burak Bayrak, Hilal Ozbek, Mehmet Koca, Songul Ceribasi, Omer Faruk Yakinci, Zuhal Guvenalp, Yücel Kadıoglu. Evaluation of anticholinesterase effect of some Epilobium species and quantification of hyperoside by HPLC. Natural product research. 2022 Mar; 36(5):1296-1299. doi: 10.1080/14786419.2020.1856841. [PMID: 33305606]
Valentina Roviello, Melinda Gilhen-Baker, Caterina Vicidomini, Giovanni N Roviello. The Healing Power of Clean Rivers: In Silico Evaluation of the Antipsoriatic Potential of Apiin and Hyperoside Plant Metabolites Contained in River Waters. International journal of environmental research and public health. 2022 02; 19(5):. doi: 10.3390/ijerph19052502. [PMID: 35270196]
Mafalda V Moreira, Sara C Pereira, Bárbara Guerra-Carvalho, David F Carrageta, Soraia Pinto, Alberto Barros, Branca M Silva, Pedro F Oliveira, Marco G Alves. Hyperoside Supplementation in Preservation Media Surpasses Vitamin C Protection Against Oxidative Stress-Induced Damages in Human Spermatozoa. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2022 Jan; 56(S1):1-23. doi: 10.33594/000000487. [PMID: 34998002]
Songsong Wang, Feiya Sheng, Liang Zou, Jianbo Xiao, Peng Li. Hyperoside attenuates non-alcoholic fatty liver disease in rats via cholesterol metabolism and bile acid metabolism. Journal of advanced research. 2021 12; 34(?):109-122. doi: 10.1016/j.jare.2021.06.001. [PMID: 35024184]
Xu Pang, Mei Wang, Shuang-Yan Wang, Jie Zhang, Ya-Peng Du, Ye Zhao, Xiao-Hui Zheng, Bai-Ping Ma. Phenolic compounds from the leaves of Crataegus pinnatifida Bge. var. major N.E.Br. And their lipid-lowering effects. Bioorganic & medicinal chemistry letters. 2021 09; 47(?):128211. doi: 10.1016/j.bmcl.2021.128211. [PMID: 34157392]
Yongkang Yang, Jing Li, Tingcai Rao, Zhirui Fang, Junyan Zhang. The role and mechanism of hyperoside against myocardial infarction in mice by regulating autophagy via NLRP1 inflammation pathway. Journal of ethnopharmacology. 2021 Aug; 276(?):114187. doi: 10.1016/j.jep.2021.114187. [PMID: 33957207]
Di Wu, Lan Tang, Ran Duan, Xia Hu, Fang Geng, Yin Zhang, Lianxin Peng, Hui Li. Interaction mechanisms and structure-affinity relationships between hyperoside and soybean β-conglycinin and glycinin. Food chemistry. 2021 Jun; 347(?):129052. doi: 10.1016/j.foodchem.2021.129052. [PMID: 33482484]
Jing Zhao, Saisai Tian, Dong Lu, Jian Yang, Huawu Zeng, Feng Zhang, Dongzhu Tu, Guangbo Ge, Yuejuan Zheng, Ting Shi, Xin Xu, Shiyi Zhao, Yili Yang, Weidong Zhang. Systems pharmacological study illustrates the immune regulation, anti-infection, anti-inflammation, and multi-organ protection mechanism of Qing-Fei-Pai-Du decoction in the treatment of COVID-19. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2021 May; 85(?):153315. doi: 10.1016/j.phymed.2020.153315. [PMID: 32978039]
Xiulan Xin, Liang Chen, Ye Li, Ran Yu, Haitao Fan, Zheng Yan, Shuangshi Li, Hui Feng. Study on the interaction of hyperoside and human serum albumin in VC and VC -free environments by spectroscopic and molecular docking techniques. Luminescence : the journal of biological and chemical luminescence. 2021 May; 36(3):595-605. doi: 10.1002/bio.3978. [PMID: 33140531]
Wei-Rong Ma, Yong Tan. [The Effect and Mechanism of Hyperin on Ovarian Reserve of Tripterygium Glycosides-Induced POI Mice]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 2021 May; 52(3):458-466. doi: 10.12182/20210560103. [PMID: 34018365]
Qing Yang, Zhihua Song, Biying Dong, Lili Niu, Hongyan Cao, Hanghang Li, Tingting Du, Tengyue Liu, Wanlong Yang, Dong Meng, Yujie Fu. Hyperoside regulates its own biosynthesis via MYB30 in promoting reproductive development and seed set in okra. Plant physiology. 2021 04; 185(3):951-968. doi: 10.1093/plphys/kiaa068. [PMID: 33743011]
Yali Zhang, Xiaomin Yu, Mimi Wang, Yan Ding, Hui Guo, Jiankang Liu, Ying Cheng. Hyperoside from Z. bungeanum leaves restores insulin secretion and mitochondrial function by regulating pancreatic cellular redox status in diabetic mice. Free radical biology & medicine. 2021 01; 162(?):412-422. doi: 10.1016/j.freeradbiomed.2020.10.320. [PMID: 33161043]
Yufei Feng, Guozhao Qin, Shuyuan Chang, Zhongxu Jing, Yanyan Zhang, Yanhong Wang. Antitumor Effect of Hyperoside Loaded in Charge Reversed and Mitochondria-Targeted Liposomes. International journal of nanomedicine. 2021; 16(?):3073-3089. doi: 10.2147/ijn.s297716. [PMID: 33953556]
Jialing Liu, Yanmei Zhang, Hongqin Sheng, Chunling Liang, Huazhen Liu, Jose Alberto Moran Guerrero, Zhaoyu Lu, Wei Mao, Zhenhua Dai, Xusheng Liu, Lei Zhang. Hyperoside Suppresses Renal Inflammation by Regulating Macrophage Polarization in Mice With Type 2 Diabetes Mellitus. Frontiers in immunology. 2021; 12(?):733808. doi: 10.3389/fimmu.2021.733808. [PMID: 34925317]
Jingbo Zhou, Shu Zhang, Xinyi Sun, Yan Lou, Jiangyi Yu. Hyperoside Protects HK-2 Cells Against High Glucose-Induced Apoptosis and Inflammation via the miR-499a-5p/NRIP1 Pathway. Pathology oncology research : POR. 2021; 27(?):629829. doi: 10.3389/pore.2021.629829. [PMID: 34257594]
Songul Karakaya, Ipek Süntar, Omer Faruk Yakinci, Oksana Sytar, Songul Ceribasi, Benan Dursunoglu, Hilal Ozbek, Zuhal Guvenalp. In vivo bioactivity assessment on Epilobium species: A particular focus on Epilobium angustifolium and its components on enzymes connected with the healing process. Journal of ethnopharmacology. 2020 Nov; 262(?):113207. doi: 10.1016/j.jep.2020.113207. [PMID: 32730870]
Tao Xu, Xiao Wu, Zhou Zhou, Yu Ye, Chaoting Yan, Nanshan Zhuge, Jinhua Yu. Hyperoside ameliorates periodontitis in rats by promoting osteogenic differentiation of BMSCs via activation of the NF-κB pathway. FEBS open bio. 2020 09; 10(9):1843-1855. doi: 10.1002/2211-5463.12937. [PMID: 32687664]
Aiwu Wei, Yanli Song, Tingting Ni, Huidongzi Xiao, Yanrong Wan, Xingxing Ren, Huijuan Li, Guangli Xu. Hyperoside attenuates pregnancy loss through activating autophagy and suppressing inflammation in a rat model. Life sciences. 2020 Aug; 254(?):117735. doi: 10.1016/j.lfs.2020.117735. [PMID: 32360572]
Jianwen Cao, Cheng Tang, Manman Gao, Yanggang Rui, Jie Zhang, Li Wang, Yang Wang, Bo Xu, Bing Chun Yan. Hyperoside alleviates epilepsy-induced neuronal damage by enhancing antioxidant levels and reducing autophagy. Journal of ethnopharmacology. 2020 Jul; 257(?):112884. doi: 10.1016/j.jep.2020.112884. [PMID: 32311482]
Qing Yang, Biying Dong, Litao Wang, Zhihua Song, Lili Niu, Hanghang Li, Hongyan Cao, Dong Meng, Yujie Fu. CDPK6 phosphorylates and stabilizes MYB30 to promote hyperoside biosynthesis that prolongs the duration of full-blooming in okra. Journal of experimental botany. 2020 07; 71(14):4042-4056. doi: 10.1093/jxb/eraa174. [PMID: 32249299]
Cezara Zagrean-Tuza, Augustin C Mot, Tomasz Chmiel, Attila Bende, Ioan Turcu. Sugar matters: sugar moieties as reactivity-tuning factors in quercetin O-glycosides. Food & function. 2020 Jun; 11(6):5293-5307. doi: 10.1039/d0fo00319k. [PMID: 32458896]
Jensen A Lund, Paula N Brown, Paul R Shipley. Quantification of North American and European Crataegus flavonoids by nuclear magnetic resonance spectrometry. Fitoterapia. 2020 Jun; 143(?):104537. doi: 10.1016/j.fitote.2020.104537. [PMID: 32145312]
Wei Zhang, Zhi-Tian Fu, Yao Xie, Zhi-Wen Duan, Yu Wang, Rong-Hua Fan. High resolution UPLC-MS/MS method for simultaneous separation and determination of six flavonoids from semen cuscutae extract in rat plasma: application to comparative pharmacokinetic studies in normal and kidney-deficient rats. Natural product research. 2020 May; 34(10):1446-1451. doi: 10.1080/14786419.2018.1511556. [PMID: 30375249]
Li Yu, Wenli Wu, Yiying Pan, Wei Wang, Leiwen Sun, Yi Liu, Dongmei Wang, Dengwu Li. Quality evaluation of different varieties of Zanthoxylum bungeanum Maxim. peels based on phenolic profiles, bioactivity, and HPLC fingerprint. Journal of food science. 2020 Apr; 85(4):1090-1097. doi: 10.1111/1750-3841.15095. [PMID: 32147833]
Khouchlaa Aya, Tijane M'hamed. Chemical compounds, antioxidant activity, and in vitro and in silico litholytic effects of Zizyphus lotus extracts. Journal of basic and clinical physiology and pharmacology. 2020 Mar; 31(3):. doi: 10.1515/jbcpp-2019-0091. [PMID: 32229663]
Dan Chen, Ya-Xian Wu, Yu-Bao Qiu, Bin-Bin Wan, Gang Liu, Jun-Liang Chen, Mu-Dan Lu, Qing-Feng Pang. Hyperoside suppresses hypoxia-induced A549 survival and proliferation through ferrous accumulation via AMPK/HO-1 axis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2020 Feb; 67(?):153138. doi: 10.1016/j.phymed.2019.153138. [PMID: 31881478]
Huanhuan Li, Xuexiao Cao, Yanan Liu, Tingting Liu, Meng Wang, Xiaoliang Ren, Zhiying Dou. Establishment of modified biopharmaceutics classification system absorption model for oral Traditional Chinese Medicine (Sanye Tablet). Journal of ethnopharmacology. 2019 Nov; 244(?):112148. doi: 10.1016/j.jep.2019.112148. [PMID: 31400507]
Katarzyna Szewczyk, Serhat Sezai Cicek, Christian Zidorn, Sebastian Granica. Phenolic constituents of the aerial parts of Impatiens glandulifera Royle (Balsaminaceae) and their antioxidant activities. Natural product research. 2019 Oct; 33(19):2851-2855. doi: 10.1080/14786419.2018.1499644. [PMID: 30175924]
Jolanta Orzelska-Górka, Katarzyna Szewczyk, Monika Gawrońska-Grzywacz, Ewa Kędzierska, Ewelina Głowacka, Mariola Herbet, Jarosław Dudka, Grażyna Biała. Monoaminergic system is implicated in the antidepressant-like effect of hyperoside and protocatechuic acid isolated from Impatiens glandulifera Royle in mice. Neurochemistry international. 2019 09; 128(?):206-214. doi: 10.1016/j.neuint.2019.05.006. [PMID: 31077758]
Xiaowei Nie, Wenjie Sheng, Daorong Hou, Qiang Liu, Ronggen Wang, Yong Tan. Effect of Hyperin and Icariin on steroid hormone secretion in rat ovarian granulosa cells. Clinica chimica acta; international journal of clinical chemistry. 2019 Aug; 495(?):646-651. doi: 10.1016/j.cca.2018.05.004. [PMID: 29729232]
Lin Wu, Qing Li, Simeng Liu, Xiaofei An, Zhimin Huang, Bo Zhang, Yanggang Yuan, Changying Xing. Protective effect of hyperoside against renal ischemia-reperfusion injury via modulating mitochondrial fission, oxidative stress, and apoptosis. Free radical research. 2019 Jul; 53(7):727-736. doi: 10.1080/10715762.2019.1623883. [PMID: 31130024]
Yaoping Shi, Xiaoxia Qiu, Mengjun Dai, Xuebin Zhang, Guangxin Jin. Hyperoside Attenuates Hepatic Ischemia-Reperfusion Injury by Suppressing Oxidative Stress and Inhibiting Apoptosis in Rats. Transplantation proceedings. 2019 Jul; 51(6):2051-2059. doi: 10.1016/j.transproceed.2019.04.066. [PMID: 31399183]
Yumi Kitahiro, Hiroshi Ikeda, Hyoung-Tak Im, Eiichi Kodaira, Makio Shibano. Phytochemical characterization of Rosa multiflora Thunb. (Rosaceae) in Japan and South Korea, with a focus on the bioactive flavonol glycoside 'multiflorin A'. Journal of natural medicines. 2019 Jun; 73(3):555-565. doi: 10.1007/s11418-019-01302-x. [PMID: 30949951]
Jingxia Han, Jing Meng, Shuang Chen, Xiaorui Wang, Shan Yin, Qiang Zhang, Huijuan Liu, Rong Qin, Zhongwei Li, Weilong Zhong, Chao Zhang, Heng Zhang, Yuanhao Tang, Tingting Lin, Wanfeng Gao, Xiaoyun Zhang, Lan Yang, Yanrong Liu, Hong-Gang Zhou, Tao Sun, Cheng Yang. YY1 Complex Promotes Quaking Expression via Super-Enhancer Binding during EMT of Hepatocellular Carcinoma. Cancer research. 2019 04; 79(7):1451-1464. doi: 10.1158/0008-5472.can-18-2238. [PMID: 30760518]
Fang Liu, YuHua Zhao, JieMin Lu, ShuangHui Chen, XinGuang Zhang, WenWei Mao. Hyperoside inhibits proinflammatory cytokines in human lung epithelial cells infected with Mycoplasma pneumoniae. Molecular and cellular biochemistry. 2019 Mar; 453(1-2):179-186. doi: 10.1007/s11010-018-3443-4. [PMID: 30350306]
Buhui Liu, Yue Tu, Weiming He, Yinglu Liu, Wei Wu, Qijun Fang, Haitao Tang, Renmao Tang, Ziyue Wan, Wei Sun, Yigang Wan. Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy. Aging. 2018 12; 10(12):4197-4212. doi: 10.18632/aging.101723. [PMID: 30585174]
Seon-A Jang, Dae Won Park, Eun Hwa Sohn, Sung Ryul Lee, Se Chan Kang. Hyperoside suppresses tumor necrosis factor α-mediated vascular inflammatory responses by downregulating mitogen-activated protein kinases and nuclear factor-κB signaling. Chemico-biological interactions. 2018 Oct; 294(?):48-55. doi: 10.1016/j.cbi.2018.08.013. [PMID: 30125551]
Lizhen Liu, Zhi Mi, Qin Hu, Caiqing Li, Xiaohua Li, Feng Feng. One-step synthesis of fluorescent carbon dots for sensitive and selective detection of hyperin. Talanta. 2018 Aug; 186(?):315-321. doi: 10.1016/j.talanta.2018.04.065. [PMID: 29784367]
Zhaochen Wu, Wei Wang, Fengyuan He, Dengwu Li, Dongmei Wang. Simultaneous Enrichment and Separation of Four Flavonoids from Zanthoxylum bungeanum Leaves by Ultrasound-Assisted Extraction and Macroporous Resins with Evaluation of Antioxidant Activities. Journal of food science. 2018 Aug; 83(8):2109-2118. doi: 10.1111/1750-3841.14282. [PMID: 30080245]
Dong Wu, Danmeng Yu, Yujia Zhang, Juane Dong, Dengwu Li, Dongmei Wang. Metabolite Profiles, Bioactivity, and HPLC Fingerprint of Different Varieties of Eucommia ulmoides Oliv.: Towards the Utilization of Medicinal and Commercial Chinese Endemic Tree. Molecules (Basel, Switzerland). 2018 Jul; 23(8):. doi: 10.3390/molecules23081898. [PMID: 30061494]
Yongliang Chen, Lihong Ye, Wangjian Li, Dongzhang Li, Feng Li. Hyperoside protects human kidney‑2 cells against oxidative damage induced by oxalic acid. Molecular medicine reports. 2018 Jul; 18(1):486-494. doi: 10.3892/mmr.2018.8948. [PMID: 29750296]
Sławomir Dresler, Jozef Kováčik, Maciej Strzemski, Ireneusz Sowa, Magdalena Wójciak-Kosior. Methodological aspects of biologically active compounds quantification in the genus Hypericum. Journal of pharmaceutical and biomedical analysis. 2018 Jun; 155(?):82-90. doi: 10.1016/j.jpba.2018.03.048. [PMID: 29621655]
Ze-Hua Liu, Zi-Wen Luo, Deng-Wu Li, Dong-Mei Wang, Xia Ji. Synergistic effects and related bioactive mechanisms of Potentilla fruticosa Linn. leaves combined with green tea polyphenols studied with microbial test system (MTS). Natural product research. 2018 Jun; 32(11):1287-1290. doi: 10.1080/14786419.2017.1333989. [PMID: 28602107]
Muzaffer Silinsin, Ercan Bursal. UHPLC-MS/MS phenolic profiling and in vitro antioxidant activities of Inula graveolens (L.) Desf. Natural product research. 2018 Jun; 32(12):1467-1471. doi: 10.1080/14786419.2017.1350673. [PMID: 28697630]
Yan-Qiang Zhou, Yin-Tao Zhao, Xiao-Yan Zhao, Cui Liang, Ya-Wei Xu, Ling Li, Yuan Liu, Hai-Bo Yang. Hyperoside Suppresses Lipopolysaccharide-induced Inflammation and Apoptosis in Human Umbilical Vein Endothelial Cells. Current medical science. 2018 Apr; 38(2):222-228. doi: 10.1007/s11596-018-1869-2. [PMID: 30074179]
Li-Min Wang, Ming-Yuan Zhang, Qiu-Shuang Zhu, Chun-Feng Lu, Xue Bai. Hyperin Enhances the Sensitivity of HCT8/VCR Colon Cancer Cell Line to Vincristine by Down-Regulating P-Glycoprotein. Clinical laboratory. 2018 Mar; 64(3):269-275. doi: 10.7754/clin.lab.2017.170923. [PMID: 29739100]
Yali Zhang, Mimi Wang, Huanhuan Dong, Xiaomin Yu, Jingfang Zhang. Anti-hypoglycemic and hepatocyte-protective effects of hyperoside from Zanthoxylum bungeanum leaves in mice with high-carbohydrate/high-fat diet and alloxan-induced diabetes. International journal of molecular medicine. 2018 Jan; 41(1):77-86. doi: 10.3892/ijmm.2017.3211. [PMID: 29115390]
Rui Xiao, An-Li Xiang, Hong-Bo Pang, Ke-Qiang Liu. Hyperoside protects against hypoxia/reoxygenation induced injury in cardiomyocytes by suppressing the Bnip3 expression. Gene. 2017 Sep; 629(?):86-91. doi: 10.1016/j.gene.2017.07.063. [PMID: 28754633]
Liyi Zou, Shaoru Chen, Li Li, Tie Wu. The protective effect of hyperoside on carbon tetrachloride-induced chronic liver fibrosis in mice via upregulation of Nrf2. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 2017 Sep; 69(7):451-460. doi: 10.1016/j.etp.2017.04.001. [PMID: 28434817]
Lijun Sun, Dongjie Liu, Jiaojiao Sun, Xingbin Yang, Minghai Fu, Yurong Guo. Simultaneous separation and purification of chlorogenic acid, epicatechin, hyperoside and phlorizin from thinned young Qinguan apples by successive use of polyethylene and polyamide resins. Food chemistry. 2017 Sep; 230(?):362-371. doi: 10.1016/j.foodchem.2017.03.065. [PMID: 28407923]
Yali Zhang, Huanhuan Dong, Jingfang Zhang, Liyu Zhang. Inhibitory effect of hyperoside isolated from Zanthoxylum bungeanum leaves on SW620 human colorectal cancer cells via induction of the p53 signaling pathway and apoptosis. Molecular medicine reports. 2017 Aug; 16(2):1125-1132. doi: 10.3892/mmr.2017.6710. [PMID: 29067453]
Chengwei Niu, Man Ma, Xiao Han, Zimin Wang, Hangyan Li. Hyperin protects against cisplatin-induced liver injury in mice. Acta cirurgica brasileira. 2017 Aug; 32(8):633-640. doi: 10.1590/s0102-865020170080000005. [PMID: 28902939]
Yeli Gong, Youhua Yang, Xiaoqing Chen, Min Yang, Dan Huang, Rong Yang, Lianying Zhou, Changlei Li, Qiuju Xiong, Zhe Xiong. Hyperoside protects against chronic mild stress-induced learning and memory deficits. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017 Jul; 91(?):831-840. doi: 10.1016/j.biopha.2017.05.019. [PMID: 28501772]
Lei Wen, Yunliang Lin, Ruimin Lv, Huijiao Yan, Jinqian Yu, Hengqiang Zhao, Xiao Wang, Daijie Wang. An Efficient Method for the Preparative Isolation and Purification of Flavonoids from Leaves of Crataegus pinnatifida by HSCCC and Pre-HPLC. Molecules (Basel, Switzerland). 2017 May; 22(5):. doi: 10.3390/molecules22050767. [PMID: 28486427]
Wu-Yang Huang, Lin Fu, Chun-Yang Li, Li-Ping Xu, Li-Xia Zhang, Wei-Min Zhang. Quercetin, Hyperin, and Chlorogenic Acid Improve Endothelial Function by Antioxidant, Antiinflammatory, and ACE Inhibitory Effects. Journal of food science. 2017 May; 82(5):1239-1246. doi: 10.1111/1750-3841.13706. [PMID: 28407238]
Liancai Zhu, Jinqiu Chen, Jun Tan, Xi Liu, Bochu Wang. Flavonoids from Agrimonia pilosa Ledeb: Free Radical Scavenging and DNA Oxidative Damage Protection Activities and Analysis of Bioactivity-Structure Relationship Based on Molecular and Electronic Structures. Molecules (Basel, Switzerland). 2017 Feb; 22(3):. doi: 10.3390/molecules22030195. [PMID: 28245624]
Sang-Hyun Lee, Jung-Yun Lee, Young-In Kwon, Hae-Dong Jang. Anti-Osteoclastic Activity of Artemisia capillaris Thunb. Extract Depends upon Attenuation of Osteoclast Differentiation and Bone Resorption-Associated Acidification Due to Chlorogenic Acid, Hyperoside, and Scoparone. International journal of molecular sciences. 2017 Feb; 18(2):. doi: 10.3390/ijms18020322. [PMID: 28165389]
Hong-die Cai, Wei-wei Tao, Shu-lan Su, Sheng Guo, Yue Zhu, Jian-ming Guo, Da-wei Qian, Xu-dong Cong, Ren-mao Tang, Jin-ao Duan. [Antidepressant activity of flavonoid ethanol extract of Abelmoschus manihot corolla with BDNF up-regulation in the hippocampus]. Yao xue xue bao = Acta pharmaceutica Sinica. 2017 Feb; 52(2):222-8. doi: . [PMID: 29979503]
Tingting Ma, Yi Wang, Xiaoqian Chen, Xiaoping Zhao. [LC/MS guided approach to discovering nephroprotective substances from Huangkui capsule]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. 2017 01; 46(1):66-73. doi: 10.3785/j.issn.1008-9292.2017.02.10. [PMID: 28436633]
Huijeong Ahn, Geun-Shik Lee. Isorhamnetin and hyperoside derived from water dropwort inhibits inflammasome activation. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2017 Jan; 24(?):77-86. doi: 10.1016/j.phymed.2016.11.019. [PMID: 28160865]
Peng Du, Mingdao Lei, Yu Liu, Shilin Yang. Simultaneous Determination and Pharmacokinetic Study of Six Components in Rat Plasma by HPLC-MS/MS after Oral Administration of Acanthopanax sessiliflorus Fruit Extract. International journal of molecular sciences. 2016 Dec; 18(1):. doi: 10.3390/ijms18010045. [PMID: 28036026]
Sanawar Mansur, Rahima Abdulla, Amatjan Ayupbec, Haji Akbar Aisa. Chemical Fingerprint Analysis and Quantitative Analysis of Rosa rugosa by UPLC-DAD. Molecules (Basel, Switzerland). 2016 Dec; 21(12):. doi: 10.3390/molecules21121754. [PMID: 28009848]
Gong Chunzhi, Li Zunfeng, Qin Chengwei, Bu Xiangmei, Yu Jingui. Hyperin protects against LPS-induced acute kidney injury by inhibiting TLR4 and NLRP3 signaling pathways. Oncotarget. 2016 Dec; 7(50):82602-82608. doi: 10.18632/oncotarget.13010. [PMID: 27813491]
Le Zhang, Siyi He, Fan Yang, Hua Yu, Wei Xie, Qian Dai, Di Zhang, Xiaoqin Liu, Shiwen Zhou, Kebin Zhang. Hyperoside ameliorates glomerulosclerosis in diabetic nephropathy by downregulating miR-21. Canadian journal of physiology and pharmacology. 2016 Dec; 94(12):1249-1256. doi: 10.1139/cjpp-2016-0066. [PMID: 27704873]
Elizabeth M Mudge, Ying Liu, Jensen A Lund, Paula N Brown. Single-Laboratory Validation for the Determination of Flavonoids in Hawthorn Leaves and Finished Products by LC-UV. Planta medica. 2016 Nov; 82(17):1487-1492. doi: 10.1055/s-0042-118463. [PMID: 27776376]
Chia-Sheng Chao, Chien-Sung Tsai, Yee-Phoung Chang, Jian-Ming Chen, Hsien-Kuo Chin, Shyh-Chyun Yang. Hyperin inhibits nuclear factor kappa B and activates nuclear factor E2-related factor-2 signaling pathways in cisplatin-induced acute kidney injury in mice. International immunopharmacology. 2016 Nov; 40(?):517-523. doi: 10.1016/j.intimp.2016.09.020. [PMID: 27764742]
Hang-qing Cui, Cai-ying Peng, Ying-zheng Huang, Ying Gao, Jian-qun Liu, Rui Zhang, Ji-cheng Shu. [Flavonoids from leaves of Psidum littorale]. Yao xue xue bao = Acta pharmaceutica Sinica. 2016 11; 51(11):1745-50. doi: . [PMID: 29908132]
Baode Shen, Na Wu, Chengying Shen, Fucheng Zhang, Yan Wu, Pinghua Xu, Lihong Zhang, Wei Wu, Yi Lu, Jin Han, Yonggang Wang, Hailong Yuan. Hyperoside nanocrystals for HBV treatment: process optimization, in vitro and in vivo evaluation. Drug development and industrial pharmacy. 2016 Nov; 42(11):1772-81. doi: 10.3109/03639045.2016.1173051. [PMID: 27032257]
Jisheng Zhang, Haiyan Fu, Yan Xu, Yunfei Niu, Xiaofei An. Hyperoside reduces albuminuria in diabetic nephropathy at the early stage through ameliorating renal damage and podocyte injury. Journal of natural medicines. 2016 Oct; 70(4):740-8. doi: 10.1007/s11418-016-1007-z. [PMID: 27255369]
Gerhardt J Boukes, Maryna van de Venter. The apoptotic and autophagic properties of two natural occurring prodrugs, hyperoside and hypoxoside, against pancreatic cancer cell lines. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2016 Oct; 83(?):617-626. doi: 10.1016/j.biopha.2016.07.029. [PMID: 27459118]