5-Phosphoribosylamine (BioDeep_00000005094)
Secondary id: BioDeep_00001869387
human metabolite Endogenous
代谢物信息卡片
{[(2R,3S,4R,5R)-5-amino-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
化学式: C5H12NO7P (229.0351)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 8.73%
分子结构信息
SMILES: C(C1C(C(C(O1)N)O)O)OP(=O)(O)O
InChI: InChI=1S/C5H12NO7P/c6-5-4(8)3(7)2(13-5)1-12-14(9,10)11/h2-5,7-8H,1,6H2,(H2,9,10,11)
描述信息
5-Phosphoribosylamine is a substrate for Amidophosphoribosyltransferase and Trifunctional purine biosynthetic protein adenosine-3. [HMDB]
5-Phosphoribosylamine is a substrate for Amidophosphoribosyltransferase and Trifunctional purine biosynthetic protein adenosine-3.
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
15 个代谢物同义名
{[(2R,3S,4R,5R)-5-amino-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid; 5-Phospho-β-D-ribosylamine; 5-Phospho-beta-D-ribosyl-amine; 5-Phospho-beta-D-ribosylamine; beta-Phosphoribosyl-1-amine; 5-Phospho-β-D-ribosylamine; 5-Phospho-b-D-ribosylamine; β-Phosphoribosyl-1-amine; 5-P-beta-D-Ribosyl-amine; 5-Phospho-D-ribosylamine; 5-Phosphoribosyl-1-amine; Phosphoribosyl-1-amine; 5-Phosphoribosylamine; Phosphoribosylamine; PRA
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:37737
- KEGG: C03090
- PubChem: 439905
- PubChem: 150
- HMDB: HMDB0001128
- Metlin: METLIN63390
- Wikipedia: Phosphoribosylamine
- MetaCyc: 5-P-BETA-D-RIBOSYL-AMINE
- KNApSAcK: C00007377
- foodb: FDB022441
- chemspider: 388939
- CAS: 6062-06-2
- PMhub: MS000017795
- PubChem: 5988
- PDB-CCD: GRF
- 3DMET: B01631
- NIKKAJI: J40.074B
- RefMet: 5-Phosphoribosylamine
分类词条
相关代谢途径
Reactome(0)
BioCyc(3)
PlantCyc(0)
代谢反应
83 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(5)
- purine nucleotides de novo biosynthesis I:
adenylo-succinate ⟶ AMP + fumarate - superpathway of histidine, purine, and pyrimidine biosynthesis:
glt + imidazole acetol-phosphate ⟶ 2-oxoglutarate + L-histidinol-phosphate - purine nucleotides de novo biosynthesis II:
adenylo-succinate ⟶ AMP + fumarate - 5-aminoimidazole ribonucleotide biosynthesis I:
5-phospho-β-D-ribosyl-amine + ATP + gly ⟶ 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate - 5-aminoimidazole ribonucleotide biosynthesis II:
5-phospho-β-D-ribosyl-amine + ATP + gly ⟶ 5-phospho-ribosyl-glycineamide + ADP + H+ + phosphate
Plant Reactome(0)
INOH(1)
- Purine nucleotides and Nucleosides metabolism ( Purine nucleotides and Nucleosides metabolism ):
H2O + XTP ⟶ Pyrophosphate + XMP
PlantCyc(0)
COVID-19 Disease Map(1)
- @COVID-19 Disease
Map["name"]:
Adenosine + Pi ⟶ Adenine + _alpha_-D-Ribose 1-phosphate
PathBank(74)
- Purine Metabolism:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency:
Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate - Homocarnosinosis:
Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate - Hyperinsulinism-Hyperammonemia Syndrome:
Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate - Adenosine Deaminase Deficiency:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Adenylosuccinate Lyase Deficiency:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Gout or Kelley-Seegmiller Syndrome:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Lesch-Nyhan Syndrome (LNS):
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Molybdenum Cofactor Deficiency:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Xanthine Dehydrogenase Deficiency (Xanthinuria):
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Purine Nucleoside Phosphorylase Deficiency:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - AICA-Ribosiduria:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - 2-Hydroxyglutric Aciduria (D and L Form):
Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate - Azathioprine Action Pathway:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Mercaptopurine Action Pathway:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Thioguanine Action Pathway:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Xanthinuria Type I:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Xanthinuria Type II:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Adenine Phosphoribosyltransferase Deficiency (APRT):
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Mitochondrial DNA Depletion Syndrome-3:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Myoadenylate Deaminase Deficiency:
Deoxyadenosine + Phosphate ⟶ Adenine + Deoxyribose 1-phosphate - Succinic Semialdehyde Dehydrogenase Deficiency:
Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate - Purine Nucleotides De Novo Biosynthesis:
N(6)-(1,2-dicarboxyethyl)AMP ⟶ Adenosine monophosphate + Fumaric acid - Thiamin Diphosphate Biosynthesis:
L-Glutamine + Phosphoribosyl pyrophosphate + Water ⟶ 5-Phosphoribosylamine + L-Glutamic acid + Pyrophosphate - Purine Nucleotides De Novo Biosynthesis 2:
N(6)-(1,2-dicarboxyethyl)AMP ⟶ Adenosine monophosphate + Fumaric acid - Purine Nucleotides De Novo Biosynthesis:
N(6)-(1,2-dicarboxyethyl)AMP ⟶ Adenosine monophosphate + Fumaric acid - Glutamate Metabolism:
Adenosine triphosphate + L-Glutamine ⟶ Adenosine monophosphate + Pyrophosphate - Purine Metabolism:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - 2-Hydroxyglutric Aciduria (D and L Form):
Adenosine triphosphate + L-Glutamine + Water + Xanthylic acid ⟶ Adenosine monophosphate + Guanosine monophosphate + L-Glutamic acid + Pyrophosphate - 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency:
Adenosine triphosphate + L-Glutamine + Water + Xanthylic acid ⟶ Adenosine monophosphate + Guanosine monophosphate + L-Glutamic acid + Pyrophosphate - Adenosine Deaminase Deficiency:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Adenylosuccinate Lyase Deficiency:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - AICA-Ribosiduria:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Gout or Kelley-Seegmiller Syndrome:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Homocarnosinosis:
Adenosine triphosphate + L-Glutamine + Water + Xanthylic acid ⟶ Adenosine monophosphate + Guanosine monophosphate + L-Glutamic acid + Pyrophosphate - Hyperinsulinism-Hyperammonemia Syndrome:
Adenosine triphosphate + L-Glutamine + Water + Xanthylic acid ⟶ Adenosine monophosphate + Guanosine monophosphate + L-Glutamic acid + Pyrophosphate - Xanthine Dehydrogenase Deficiency (Xanthinuria):
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Lesch-Nyhan Syndrome (LNS):
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Molybdenum Cofactor Deficiency:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Purine Nucleoside Phosphorylase Deficiency:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Xanthinuria Type I:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Xanthinuria Type II:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Adenine Phosphoribosyltransferase Deficiency (APRT):
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Mitochondrial DNA Depletion Syndrome:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Myoadenylate Deaminase Deficiency:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Succinic Semialdehyde Dehydrogenase Deficiency:
Adenosine triphosphate + L-Glutamine + Water + Xanthylic acid ⟶ Adenosine monophosphate + Guanosine monophosphate + L-Glutamic acid + Pyrophosphate - Glutamate Metabolism:
Adenosine triphosphate + L-Glutamine + Water + Xanthylic acid ⟶ Adenosine monophosphate + Guanosine monophosphate + L-Glutamic acid + Pyrophosphate - Purine Metabolism:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Glutamate Metabolism:
Adenosine triphosphate + L-Glutamine + Water + Xanthylic acid ⟶ Adenosine monophosphate + Guanosine monophosphate + L-Glutamic acid + Pyrophosphate - Purine Metabolism:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Glutamate Metabolism:
Adenosine triphosphate + L-Glutamine + Water + Xanthylic acid ⟶ Adenosine monophosphate + Guanosine monophosphate + L-Glutamic acid + Pyrophosphate - Glutamate Metabolism:
Adenosine triphosphate + L-Glutamine + Water + Xanthylic acid ⟶ Adenosine monophosphate + Guanosine monophosphate + L-Glutamic acid + Pyrophosphate - 2-Hydroxyglutric Aciduria (D and L Form):
Adenosine triphosphate + L-Glutamine ⟶ Adenosine monophosphate + Pyrophosphate - 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency:
Adenosine triphosphate + L-Glutamine ⟶ Adenosine monophosphate + Pyrophosphate - Adenosine Deaminase Deficiency:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Adenylosuccinate Lyase Deficiency:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - AICA-Ribosiduria:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Gout or Kelley-Seegmiller Syndrome:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Homocarnosinosis:
Adenosine triphosphate + L-Glutamine ⟶ Adenosine monophosphate + Pyrophosphate - Hyperinsulinism-Hyperammonemia Syndrome:
Adenosine triphosphate + L-Glutamine ⟶ Adenosine monophosphate + Pyrophosphate - Xanthine Dehydrogenase Deficiency (Xanthinuria):
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Lesch-Nyhan Syndrome (LNS):
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Molybdenum Cofactor Deficiency:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Purine Nucleoside Phosphorylase Deficiency:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Xanthinuria Type I:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Xanthinuria Type II:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Adenine Phosphoribosyltransferase Deficiency (APRT):
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Mitochondrial DNA Depletion Syndrome:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Myoadenylate Deaminase Deficiency:
Adenosine + Phosphate ⟶ Adenine + Ribose 1-phosphate - Succinic Semialdehyde Dehydrogenase Deficiency:
Adenosine triphosphate + L-Glutamine ⟶ Adenosine monophosphate + Pyrophosphate - Purine Nucleotides De Novo Biosynthesis:
N(6)-(1,2-dicarboxyethyl)AMP ⟶ Adenosine monophosphate + Fumaric acid - Thiamin Diphosphate Biosynthesis:
L-Glutamine + Phosphoribosyl pyrophosphate + Water ⟶ 5-Phosphoribosylamine + L-Glutamic acid + Pyrophosphate - Purine Nucleotides De Novo Biosynthesis 2:
N(6)-(1,2-dicarboxyethyl)AMP ⟶ Adenosine monophosphate + Fumaric acid - Glutamate Metabolism:
Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate
2 个相关的物种来源信息
- 9606 - Homo sapiens: -
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Pawel Durek, Dirk Walther. The integrated analysis of metabolic and protein interaction networks reveals novel molecular organizing principles.
BMC systems biology.
2008 Nov; 2(?):100. doi:
10.1186/1752-0509-2-100. [PMID: 19032748] - A Puigvert, D Ruano. [Etiopathogenesis of so-called congenital hydronephrosis].
Journal d'urologie et de nephrologie.
1979 Jan; 85(1-2):1-12. doi:
NULL. [PMID: 439196] - M Yamada, J Takahashi. Effect of dietary DL-ethionine on postnatal growth, and activities of liver and kidney enzymes of male chickens, Gallus domesticus.
Comparative biochemistry and physiology. C: Comparative pharmacology.
1977; 58(2C):177-81. doi:
10.1016/0306-4492(77)90101-0. [PMID: 23931] - M Sano. Subcellular localizations of guanylate cyclase and 3',5'-cyclic nucleotide phosphodiesterase in sea urchin sperm.
Biochimica et biophysica acta.
1976 Apr; 428(2):525-31. doi:
10.1016/0304-4165(76)90061-1. [PMID: 6049]
