N-Carbamoylputrescine (BioDeep_00000004427)

 

Secondary id: BioDeep_00001869516

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


1-Amino-4-ureidobutane

化学式: C5H13N3O (131.1059)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(otcml) 3.03%

分子结构信息

SMILES: C(CCNC(=O)N)CN
InChI: InChI=1S/C5H13N3O/c6-3-1-2-4-8-5(7)9/h1-4,6H2,(H3,7,8,9)

描述信息

Alkaloid from Hordeum vulgare (barley) and Sesamum indicum (sesame). N-Carbamoylputrescine is found in many foods, some of which are new zealand spinach, cupuaçu, common oregano, and agar.
N-Carbamoylputrescine is found in cereals and cereal products. N-Carbamoylputrescine is an alkaloid from Hordeum vulgare (barley) and Sesamum indicum (sesame).

同义名列表

8 个代谢物同义名

1-Amino-4-ureidobutane; N-carbamoylputrescine; N-Carbamylputrescine; 1-(4-Aminobutyl)urea; N-(4-Aminobutyl)urea; (4-Aminobutyl)-urea; (4-Aminobutyl)urea; N-Carbamoylputrescine



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

245 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(243)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 ALB, ARG1, AZIN2, ODC1, PIK3CA, RPS6KA2, TFDP3
Nucleus 5 ALB, ARG1, AZIN2, RPS6KA2, TFDP3
cytosol 6 ALB, ARG1, AZIN2, ODC1, PIK3CA, RPS6KA2
dendrite 1 AZIN2
trans-Golgi network 1 AZIN2
centrosome 1 ALB
nucleoplasm 1 RPS6KA2
lamellipodium 1 PIK3CA
Cytoplasmic granule 1 ARG1
Synapse 1 RPS6KA2
Golgi apparatus 1 ALB
Golgi membrane 1 INS
mitochondrial inner membrane 1 OTC
plasma membrane 1 PIK3CA
Membrane 1 AZIN2
axon 1 AZIN2
extracellular exosome 1 ALB
endoplasmic reticulum 1 ALB
extracellular space 3 ALB, ARG1, INS
perinuclear region of cytoplasm 2 AZIN2, PIK3CA
intercalated disc 1 PIK3CA
mitochondrion 2 AZIN2, OTC
protein-containing complex 1 ALB
Secreted 2 ALB, INS
extracellular region 3 ALB, ARG1, INS
Mitochondrion matrix 1 OTC
mitochondrial matrix 1 OTC
anchoring junction 1 ALB
transcription regulator complex 1 TFDP3
perikaryon 1 AZIN2
cytoplasmic vesicle 1 AZIN2
cis-Golgi network 1 AZIN2
ciliary basal body 1 ALB
chromatin 1 TFDP3
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
endosome lumen 1 INS
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 ALB, INS
platelet alpha granule lumen 1 ALB
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
specific granule lumen 1 ARG1
transport vesicle 2 AZIN2, INS
azurophil granule lumen 1 ARG1
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 AZIN2, INS
endoplasmic reticulum-Golgi intermediate compartment 1 AZIN2
Golgi apparatus, cis-Golgi network 1 AZIN2
ribosome 1 RPS6KA2
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
ciliary transition fiber 1 ALB
granular vesicle 1 AZIN2


文献列表

  • Prasanthi Jegatheesan, David Ramani, Mickael Lhuillier, Naouel El-Hafaia, Radji Ramassamy, Mohamed Aboubacar, Samir Nakib, Huixiong Chen, Christiane Garbay, Nathalie Neveux, Cécile Loï, Luc Cynober, Jean-Pascal de Bandt. Is N-Carbamoyl Putrescine, the Decarboxylation Derivative of Citrulline, a Regulator of Muscle Protein Metabolism in Rats?. Nutrients. 2019 Nov; 11(11):. doi: 10.3390/nu11112637. [PMID: 31684160]
  • D Ramani, S Nakib, H Chen, C Garbay, A Loukaci, L Cynober, J P De Bandt. N-Carbamoylputrescine, a citrulline-derived polyamine, is not a significant citrulline metabolite in rats. Analytical biochemistry. 2012 Apr; 423(1):54-60. doi: 10.1016/j.ab.2011.12.040. [PMID: 22266292]
  • Piotr Bielecki, Jacek Puchałka, Melissa L Wos-Oxley, Holger Loessner, Justyna Glik, Marek Kawecki, Mariusz Nowak, Burkhard Tümmler, Siegfried Weiss, Vítor A P Martins dos Santos. In-vivo expression profiling of Pseudomonas aeruginosa infections reveals niche-specific and strain-independent transcriptional programs. PloS one. 2011; 6(9):e24235. doi: 10.1371/journal.pone.0024235. [PMID: 21931663]
  • Donald M Gardiner, Kemal Kazan, Sebastien Praud, Francois J Torney, Anca Rusu, John M Manners. Early activation of wheat polyamine biosynthesis during Fusarium head blight implicates putrescine as an inducer of trichothecene mycotoxin production. BMC plant biology. 2010 Dec; 10(?):289. doi: 10.1186/1471-2229-10-289. [PMID: 21192794]
  • Sascha Baumann, Adrianne Sander, James R Gurnon, Giane M Yanai-Balser, James L Van Etten, Markus Piotrowski. Chlorella viruses contain genes encoding a complete polyamine biosynthetic pathway. Virology. 2007 Mar; 360(1):209-17. doi: 10.1016/j.virol.2006.10.010. [PMID: 17101165]
  • Tim Janowitz, Helmut Kneifel, Markus Piotrowski. Identification and characterization of plant agmatine iminohydrolase, the last missing link in polyamine biosynthesis of plants. FEBS letters. 2003 Jun; 544(1-3):258-61. doi: 10.1016/s0014-5793(03)00515-5. [PMID: 12782327]
  • Markus Piotrowski, Tim Janowitz, Helmut Kneifel. Plant C-N hydrolases and the identification of a plant N-carbamoylputrescine amidohydrolase involved in polyamine biosynthesis. The Journal of biological chemistry. 2003 Jan; 278(3):1708-12. doi: 10.1074/jbc.m205699200. [PMID: 12435743]