Pyrazosulfuron-ethyl (BioDeep_00000001816)

 

Secondary id: BioDeep_00001868543

human metabolite blood metabolite


代谢物信息卡片


Ethyl 5-({[(4,6-dimethoxypyrimidin-2-yl)-C-hydroxycarbonimidoyl]amino}sulphonyl)-1-methyl-1H-pyrazole-4-carboxylic acid

化学式: C14H18N6O7S (414.0958)
中文名称: 吡嘧磺隆
谱图信息: 最多检出来源 Homo sapiens(plant) 38.89%

分子结构信息

SMILES: CCOC(=O)C1=C(N(C)N=C1)S(=O)(=O)NC(O)=NC1=NC(OC)=CC(OC)=N1
InChI: InChI=1S/C14H18N6O7S/c1-5-27-12(21)8-7-15-20(2)11(8)28(23,24)19-14(22)18-13-16-9(25-3)6-10(17-13)26-4/h6-7H,5H2,1-4H3,(H2,16,17,18,19,22)

描述信息

D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals

同义名列表

9 个代谢物同义名

Ethyl 5-({[(4,6-dimethoxypyrimidin-2-yl)-C-hydroxycarbonimidoyl]amino}sulphonyl)-1-methyl-1H-pyrazole-4-carboxylic acid; Ethyl 5-({[(4,6-dimethoxypyrimidin-2-yl)-C-hydroxycarbonimidoyl]amino}sulfonyl)-1-methyl-1H-pyrazole-4-carboxylic acid; Ethyl 5-({[(4,6-dimethoxypyrimidin-2-yl)-C-hydroxycarbonimidoyl]amino}sulphonyl)-1-methyl-1H-pyrazole-4-carboxylate; ethyl 5-({[(4,6-dimethoxypyrimidin-2-yl)-C-hydroxycarbonimidoyl]amino}sulfonyl)-1-methyl-1H-pyrazole-4-carboxylate; ethyl 5-{[(4,6-dimethoxypyrimidin-2-yl)-C-hydroxycarbonimidoyl]aminosulfonyl}-1-methylpyrazole-4-carboxylate; Ethyl 5-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-1-methylpyrazole-4-carboxylate; Pyrazosulphuron-ethyl; Pyrazosulfuron-ethyl; Pyrazosulfuron-ethyl



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Qian Yu, Ping Zhang, Yuhan He, Zhifeng Xu, Xiulong He, Yuan Hu, Hongjun Zhang, Lin He. Dissipation Dynamics and Residue of Four Herbicides in Paddy Fields Using HPLC-MS/MS and GC-MS. International journal of environmental research and public health. 2019 01; 16(2):. doi: 10.3390/ijerph16020236. [PMID: 30650669]
  • Xiang-Wen Luo, De-Yang Zhang, Teng-Hui Zhu, Xu-Guo Zhou, Jing Peng, Song-Bai Zhang, Yong Liu. Adaptation mechanism and tolerance of Rhodopseudomonas palustris PSB-S under pyrazosulfuron-ethyl stress. BMC microbiology. 2018 12; 18(1):207. doi: 10.1186/s12866-018-1361-y. [PMID: 30526497]
  • Yu-Ting Lee, Chang-Jun Cui, Eve W L Chow, Nason Pue, Thierry Lonhienne, Jian-Guo Wang, James A Fraser, Luke W Guddat. Sulfonylureas have antifungal activity and are potent inhibitors of Candida albicans acetohydroxyacid synthase. Journal of medicinal chemistry. 2013 Jan; 56(1):210-9. doi: 10.1021/jm301501k. [PMID: 23237384]
  • David M G Anderson, Vikki A Carolan, Susan Crosland, Kate R Sharples, Malcolm R Clench. Examination of the translocation of sulfonylurea herbicides in sunflower plants by matrix-assisted laser desorption/ionisation mass spectrometry imaging. Rapid communications in mass spectrometry : RCM. 2010 Nov; 24(22):3309-19. doi: 10.1002/rcm.4767. [PMID: 20973006]
  • Ru-Liang Xie, Tao Zhang, Ao-Cheng Cao, Xiang-Dong Mei. 4-(4-Chloro-5-methyl-3-trifluoro-meth-yl-1H-pyrazol-1-yl)-6-(prop-2-ynyl-oxy)pyrimidine. Acta crystallographica. Section E, Structure reports online. 2010 Aug; 66(Pt 9):o2307. doi: 10.1107/s1600536810031740. [PMID: 21588656]
  • Fei Ding, Wei Liu, Xi Zhang, Li-Jun Wu, Li Zhang, Ying Sun. Identification of pyrazosulfuron-ethyl binding affinity and binding site subdomain IIA in human serum albumin by spectroscopic methods. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2010 Mar; 75(3):1088-94. doi: 10.1016/j.saa.2009.12.062. [PMID: 20064739]
  • Hong-Ju Ma, Qian-Fei Zhao, Xiang-Dong Mei, Jun Ning. 4-Bromo-5-[(5,5-dimethyl-4,5-dihydro-isoxazol-3-yl)sulfonyl-meth-yl]-3-methyl-1-(2,2,2-trifluoro-ethyl)-1H-pyrazole. Acta crystallographica. Section E, Structure reports online. 2009 Oct; 65(Pt 11):o2702-3. doi: 10.1107/s1600536809040380. [PMID: 21578303]
  • Hong-Ju Ma, Qian-Fei Zhao, Xiang-Dong Mei, Jun Ning. 4-Chloro-5-[(5,5-dimethyl-4,5-dihydro-isoxazol-3-yl)sulfonyl-meth-yl]-3-methyl-1-(2,2,2-trifluoro-ethyl)-1H-pyrazole. Acta crystallographica. Section E, Structure reports online. 2009 Sep; 65(Pt 10):o2567. doi: 10.1107/s1600536809038471. [PMID: 21578005]
  • Kyoung-Jae Choi, Yeon Gyu Yu, Hoh Gyu Hahn, Jung-Do Choi, Moon-Young Yoon. Characterization of acetohydroxyacid synthase from Mycobacterium tuberculosis and the identification of its new inhibitor from the screening of a chemical library. FEBS letters. 2005 Aug; 579(21):4903-10. doi: 10.1016/j.febslet.2005.07.055. [PMID: 16111681]
  • Yong In Kuk, Ha Il Jung, Oh Do Kwon, Do Jin Lee, Nilda R Burgos, Ja Ock Guh. Sulfonylurea herbicide-resistant Monochoria vaginalis in Korean rice culture. Pest management science. 2003 Sep; 59(9):949-61. doi: 10.1002/ps.722. [PMID: 12974347]
  • M S Yun, I S Shim, K Usui. Involvement of cytochrome P-450 enzyme activity in the selectivity and safening action of pyrazosulfuron-ethyl. Pest management science. 2001 Mar; 57(3):283-8. doi: 10.1002/ps.298. [PMID: 11455659]