Spiramycin II (BioDeep_00000009403)

   

natural product


代谢物信息卡片


acetylspiramycin

化学式: C45H76N2O15 (884.5245426)
中文名称: 乙酰螺旋霉素
谱图信息: 最多检出来源 Escherichia coli(natural_products) 50%

分子结构信息

SMILES: CC1CC=CC=CC(C(CC(C(C(C(CC(=O)O1)OC(=O)C)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)OC4CCC(C(O4)C)N(C)C
InChI: InChI=1S/C45H76N2O15/c1-25-22-31(20-21-48)41(62-44-39(51)38(47(10)11)40(28(4)58-44)61-37-24-45(7,53)43(52)29(5)57-37)42(54-12)34(59-30(6)49)23-35(50)55-26(2)16-14-13-15-17-33(25)60-36-19-18-32(46(8)9)27(3)56-36/h13-15,17,21,25-29,31-34,36-44,51-53H,16,18-20,22-24H2,1-12H3/b14-13+,17-15+/t25-,26-,27+,28-,29+,31+,32+,33+,34-,36+,37+,38-,39-,40-,41+,42+,43+,44+,45-/m1/s1

描述信息

D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007933 - Leucomycins
A macrolide antibiotic produced by various Streptomyces species.
Same as: D02420

同义名列表

3 个代谢物同义名

acetylspiramycin; Spiramycin II; Spiramycin 2



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xiaoli Lv, Pingping Yu. Early diagnosis and successful treatment of acquired toxoplasmosis infectious retinochoroiditis: A case report. Medicine. 2018 Jun; 97(26):e11231. doi: 10.1097/md.0000000000011231. [PMID: 29952985]
  • Hong-xia Tang, Xue-feng Xiong, Zhi-qiang Qin. [Clinical experience on treating Toxoplasma gondii infection during pregnancy by using acetyl spiramycin combined with azithromycin]. Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control. 2013 Oct; 25(5):555-6. doi: . [PMID: 24490384]
  • Xin-jun Luan, Zheng-hua Song, Zhen Xiao. Monitoring sub-nanogram amount of acetylspiramycin in human urine using flow injection analysis with chemiluminescence detection. Yao xue xue bao = Acta pharmaceutica Sinica. 2004 Jan; 39(1):64-7. doi: NULL. [PMID: 15127585]
  • Z Li, G Chen. [Evaluation of theophylline population pharmacokinetics in adult hospitalized patients using NONMEM analysis]. Zhongguo yao li xue bao = Acta pharmacologica Sinica. 1994 May; 15(3):267-70. doi: NULL. [PMID: 7976385]
  • A Kondo, T Nakatani, Y Kuzuya, H Suzuki, H Sano, K Yamaguchi, K Shirahata, K Takahashi, K Kita, Y Nishiie. [Studies on acetylspiramycin. 1. Separation and chemical structures of acetylspiramycin components]. The Japanese journal of antibiotics. 1990 Jun; 43(6):1152-63. doi: . [PMID: 2232146]
  • A Ito, K Murohashi, M Matsumura, A Honda, I Maruta, K Obara. [Experience in treatment of Mycoplasma pneumoniae with acetylspiramycin]. The Japanese journal of antibiotics. 1983 Apr; 36(4):699-708. doi: . [PMID: 6410100]
  • A Inoue, T Deguchi. [The pharmacokinetic studies on spiramycin and acetylspiramycin in rats]. The Japanese journal of antibiotics. 1982 Aug; 35(8):1998-2004. doi: . [PMID: 7154248]
  • F M Espinas, Y Odakura, N Suzuki, H Sasaki. [Studies on the therapeutics of experimental toxoplasmosis. I. Effect of acetylspiramycin and spiramycin on the intracardiac Toxoplasma multiplication in mice infected with Toxoplasma gondii (author's transl)]. The Japanese journal of antibiotics. 1981 Aug; 34(8):1141-7. doi: . [PMID: 7321193]