evocarpine (BioDeep_00000000863)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(Z)-1-Methyl-2-(tridec-8-en-1-yl)quinolin-4(1H)-one

化学式: C23H33NO (339.25620080000004)
中文名称: 吴茱萸喹酮碱, 吴茱萸卡品碱, 吴茱萸新碱
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 37.5%

分子结构信息

SMILES: CCCCC=CCCCCCCCC1=CC(=O)C2=CC=CC=C2N1C
InChI: InChI=1S/C23H33NO/c1-3-4-5-6-7-8-9-10-11-12-13-16-20-19-23(25)21-17-14-15-18-22(21)24(20)2/h6-7,14-15,17-19H,3-5,8-13,16H2,1-2H3/b7-6+

描述信息

Evocarpine is a member of quinolines.
Evocarpine is a natural product found in Tetradium ruticarpum with data available.
1-methyl-2-[(E)-tridec-8-enyl]quinolin-4-one is a natural product found in Tetradium ruticarpum with data available.
Evocarpine, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca2+ influx through voltage-dependent calcium channels. Antimycobacterial activity[1][2].
Evocarpine, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca2+ influx through voltage-dependent calcium channels. Antimycobacterial activity[1][2].

同义名列表

12 个代谢物同义名

(Z)-1-Methyl-2-(tridec-8-en-1-yl)quinolin-4(1H)-one; 1-methyl-2-[(z)-8-tridecenyl]-4-(1h)-quinolone; 1-methyl-2-[(Z)-tridec-8-enyl]quinolin-4-one; evocarpine; 1-methyl-2-[(Z)-tridec-8-enyl]-4-quinolinone; 1-methyl-2-[(Z)-tridec-8-enyl]-4-quinolone; (E)-1-Methyl-2-(tridec-8-en-1-yl)quinolin-4(1H)-one; 1-Methyl-2-[(8E)-8-tridecenyl]-4(1H)-quinolinone #; 1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone; 1-methyl-2-[(E)-tridec-8-enyl]quinolin-4-one; 4(1H)-Quinolone, 1-methyl-2-(8-tridecenyl)-; HWFYWIVOYBPLQU-VOTSOKGWSA-N



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

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BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Shasank S Swain, Sanghamitra Pati, Tahziba Hussain. Quinoline heterocyclic containing plant and marine candidates against drug-resistant Mycobacterium tuberculosis: A systematic drug-ability investigation. European journal of medicinal chemistry. 2022 Mar; 232(?):114173. doi: 10.1016/j.ejmech.2022.114173. [PMID: 35168150]
  • C Hochfellner, D Evangelopoulos, M Zloh, A Wube, J D Guzman, T D McHugh, O Kunert, S Bhakta, F Bucar. Antagonistic effects of indoloquinazoline alkaloids on antimycobacterial activity of evocarpine. Journal of applied microbiology. 2015 Apr; 118(4):864-72. doi: 10.1111/jam.12753. [PMID: 25604161]
  • Xiaobei Pan, S W Annie Bligh, Eileen Smith. Quinolone alkaloids from Fructus Euodiae show activity against methicillin-resistant Staphylococcus aureus. Phytotherapy research : PTR. 2014 Feb; 28(2):305-7. doi: 10.1002/ptr.4987. [PMID: 24497124]
  • Y Kano, X F Chen, S Kanemaki, Q Zong, K Komatsu. Pharmacological properties of galenical preparation. XV. Pharmacokinetics study of evocarpine and its metabolite in rats. Chemical & pharmaceutical bulletin. 1991 Nov; 39(11):3064-6. doi: 10.1248/cpb.39.3064. [PMID: 1666026]
  • Y Kano, Z Qine, K Komatsu. [On the evaluation of the preparation of Chinese medicinal prescriptions. VI. The changes of the alkaloid contents by processing of Evodia fruit]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1991 Jan; 111(1):32-5. doi: 10.1248/yakushi1947.111.1_32. [PMID: 1647452]