Vobasine (BioDeep_00000007262)
natural product
代谢物信息卡片
化学式: C21H24N2O3 (352.17868339999995)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC=C1CN(C)C2Cc3c([nH]c4ccccc34)C(=O)CC1C2C(=O)OC
InChI: InChI=1S/C21H24N2O3/c1-4-12-11-23(2)17-9-15-13-7-5-6-8-16(13)22-20(15)18(24)10-14(12)19(17)21(25)26-3/h4-8,14,17,19,22H,9-11H2,1-3H3/b12-4-/t14-,17+,19?/m0/s1
描述信息
An indole alkaloid that is vobasan in which the bridgehead methyl group is substituted by a methoxycarbonyl group and an additional oxo substituent is present in the 3-position.
同义名列表
2 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:10015
- KEGG: C09253
- PubChem: 5281415
- PubChem: 320369
- Metlin: METLIN67554
- KNApSAcK: C00001786
- CAS: 2134-83-0
- MoNA: CCMSLIB00004680083
- PMhub: MS000020572
- MetaboLights: MTBLC10015
- PubChem: 11444
- 3DMET: B05344
- NIKKAJI: J13.796K
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 761067 - Tabernaemontana eglandulosa: 10.1002/HLCA.19750580405
- 761084 - Tabernaemontana odoratissima:
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Dawn Su-Yin Sim, Sin-Yee Tang, Yun-Yee Low, Siew-Huah Lim, Toh-Seok Kam. Vobasine, vincamine, voaphylline, tacaman, and iboga alkaloids from Tabernaemontana corymbosa.
Phytochemistry.
2022 Nov; 203(?):113384. doi:
10.1016/j.phytochem.2022.113384
. [PMID: 36007666] - Hugues Fouotsa, Pierre Le Pogam, Pierre Mkounga, Alain Meli Lannang, Guillaume Bernadat, Jérôme Vanheuverzwijn, Zhiyu Zhou, Karine Leblanc, Somia Rharrabti, Augustin Ephrem Nkengfack, Jean-François Gallard, Véronique Fontaine, Franck Meyer, Erwan Poupon, Mehdi A Beniddir. Voatriafricanines A and B, Trimeric Vobasine-Aspidosperma-Aspidosperma Alkaloids from Voacanga africana.
Journal of natural products.
2021 10; 84(10):2755-2761. doi:
10.1021/acs.jnatprod.1c00812
. [PMID: 34569237] - Puteri Amelia, Alfarius Eko Nugroho, Yusuke Hirasawa, Toshio Kaneda, Takahiro Tougan, Toshihiro Horii, Hiroshi Morita. Two new bisindole alkaloids from Tabernaemontana macrocarpa Jack.
Journal of natural medicines.
2021 Jun; 75(3):633-642. doi:
10.1007/s11418-021-01510-4
. [PMID: 33822287] - Elvis Otogo N'Nang, Pierre Le Pogam, Thiery Ndong Mba, Cédric Sima Obiang, Elisabeth Mouray, Philippe Grellier, Brice Kumulungui, Pierre Champy, Mehdi A Beniddir. Targeted Isolation of Hemitheion from Mostuea brunonis, a Proposed Biosynthetic Intermediate of Theionbrunonines.
Journal of natural products.
2021 04; 84(4):1409-1413. doi:
10.1021/acs.jnatprod.1c00143
. [PMID: 33825474] - Dawn Su-Yin Sim, Wuen-Yew Teoh, Kae-Shin Sim, Siew-Huah Lim, Noel F Thomas, Yun-Yee Low, Toh-Seok Kam. Vobatensines A-F, Cytotoxic Iboga-Vobasine Bisindoles from Tabernaemontana corymbosa.
Journal of natural products.
2016 Apr; 79(4):1048-55. doi:
10.1021/acs.jnatprod.5b01117
. [PMID: 26918761] - Hong-Mei Chen, Yu-Ting Yang, Hong-Xiang Li, Zhi-Xing Cao, Xiao-Mei Dan, Ling Mei, Da-Le Guo, Chuan-Xia Song, Yu Dai, Jia Hu, Yun Deng. Cytotoxic monoterpenoid indole alkaloids isolated from the barks of Voacanga africana Staph.
Natural product research.
2016; 30(10):1144-9. doi:
10.1080/14786419.2015.1046132
. [PMID: 26140390] - Alfarius E Nugroho, Yusuke Hirasawa, Nobuo Kawahara, Yukihiro Goda, Khalijah Awang, A Hamid A Hadi, Hiroshi Morita. Bisnicalaterine A, a vobasine-vobasine bisindole alkaloid from Hunteria zeylanica.
Journal of natural products.
2009 Aug; 72(8):1502-6. doi:
10.1021/np900115q
. [PMID: 19388660] - Tayyab A Mansoor, Rita M Ramalho, Silva Mulhovo, Cecília M P Rodrigues, Maria José U Ferreira. Induction of apoptosis in HuH-7 cancer cells by monoterpene and beta-carboline indole alkaloids isolated from the leaves of Tabernaemontana elegans.
Bioorganic & medicinal chemistry letters.
2009 Aug; 19(15):4255-8. doi:
10.1016/j.bmcl.2009.05.104
. [PMID: 19525111] - Kornkanok Ingkaninan, Kanokwan Changwijit, Khanit Suwanborirux. Vobasinyl-iboga bisindole alkaloids, potent acetylcholinesterase inhibitors from Tabernaemontana divaricata root.
The Journal of pharmacy and pharmacology.
2006 Jun; 58(6):847-52. doi:
10.1211/jpp.58.6.0015
. [PMID: 16734986]