1-Deoxy-D-xylulose (BioDeep_00000006102)

 

Secondary id: BioDeep_00001869506

human metabolite Endogenous natural product


代谢物信息卡片


(2S,3S,4R)-2-(hydroxymethyl)oxolane-3,4-diol

化学式: C5H10O4 (134.0579)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(lipidsearch) 35.24%

分子结构信息

SMILES: C1C(C(C(O1)CO)O)O
InChI: InChI=1S/C5H10O4/c1-3(7)5(9)4(8)2-6/h4-6,8-9H,2H2,1H3

描述信息

1-Deoxy-D-xylulose is a product of the splitting up of Pyridoxine (an intermediate in Vitamin B6 metabolism) into two components (the other one being 4-Hydroxy-L-threonine). (KEGG) [HMDB]
1-Deoxy-D-xylulose is a product of the splitting up of Pyridoxine (an intermediate in Vitamin B6 metabolism) into two components (the other one being 4-Hydroxy-L-threonine). (KEGG).

同义名列表

5 个代谢物同义名

(2S,3S,4R)-2-(hydroxymethyl)oxolane-3,4-diol; 3,4,5-trihydroxypentan-2-one; 1-Deoxy-D-xylulose; 1-Deoxy-xylulose; 1-Deoxy-D-xylulose



数据库引用编号

21 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

6 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Adam Jozwiak, Agata Lipko, Magdalena Kania, Witold Danikiewicz, Liliana Surmacz, Agnieszka Witek, Jacek Wojcik, Konrad Zdanowski, Cezary Pączkowski, Tadeusz Chojnacki, Jaroslaw Poznanski, Ewa Swiezewska. Modeling of Dolichol Mass Spectra Isotopic Envelopes as a Tool to Monitor Isoprenoid Biosynthesis. Plant physiology. 2017 Jun; 174(2):857-874. doi: 10.1104/pp.17.00036. [PMID: 28385729]
  • Denis Tritsch, Andréa Hemmerlin, Thomas J Bach, Michel Rohmer. Plant isoprenoid biosynthesis via the MEP pathway: in vivo IPP/DMAPP ratio produced by (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase in tobacco BY-2 cell cultures. FEBS letters. 2010 Jan; 584(1):129-34. doi: 10.1016/j.febslet.2009.11.010. [PMID: 19903472]
  • Tomoki Sando, Shinya Takeno, Norie Watanabe, Hiroshi Okumoto, Tomohisa Kuzuyama, Atsushi Yamashita, Masahira Hattori, Naotake Ogasawara, Eiichiro Fukusaki, Akio Kobayashi. Cloning and characterization of the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway genes of a natural-rubber producing plant, Hevea brasiliensis. Bioscience, biotechnology, and biochemistry. 2008 Nov; 72(11):2903-17. doi: 10.1271/bbb.80387. [PMID: 18997428]
  • Kazunori Okada, Hiroyuki Kasahara, Shinjiro Yamaguchi, Hiroshi Kawaide, Yuji Kamiya, Hideaki Nojiri, Hisakazu Yamane. Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. Plant & cell physiology. 2008 Apr; 49(4):604-16. doi: 10.1093/pcp/pcn032. [PMID: 18303110]
  • Andréa Hemmerlin, Denis Tritsch, Michael Hartmann, Karine Pacaud, Jean-François Hoeffler, Alain van Dorsselaer, Michel Rohmer, Thomas J Bach. A cytosolic Arabidopsis D-xylulose kinase catalyzes the phosphorylation of 1-deoxy-D-xylulose into a precursor of the plastidial isoprenoid pathway. Plant physiology. 2006 Oct; 142(2):441-57. doi: 10.1104/pp.106.086652. [PMID: 16920870]
  • Daniela Hampel, Armin Mosandl, Matthias Wüst. Biosynthesis of mono- and sesquiterpenes in strawberry fruits and foliage: 2H labeling studies. Journal of agricultural and food chemistry. 2006 Feb; 54(4):1473-8. doi: 10.1021/jf0523972. [PMID: 16478276]
  • Ei'ichiro Fukusaki, Shinya Takeno, Takeshi Bamba, Hiroshi Okumoto, Hiroko Katto, Shin'ichiro Kajiyama, Akio Kobayashi. Biosynthetic pathway for the C45 polyprenol, solanesol, in tobacco. Bioscience, biotechnology, and biochemistry. 2004 Sep; 68(9):1988-90. doi: 10.1271/bbb.68.1988. [PMID: 15388978]
  • Ines Neundorf, Christian Köhler, Lothar Hennig, Matthias Findeisen, Duilio Arigoni, Peter Welzel. Evidence for the combined participation of a C10 and a C15 precursor in the biosynthesis of moenocinol, the lipid part of the moenomycin antibiotics. Chembiochem : a European journal of chemical biology. 2003 Nov; 4(11):1201-5. doi: 10.1002/cbic.200300622. [PMID: 14613112]
  • Wanchai De-Eknamkul, Buppachart Potduang. Biosynthesis of beta-sitosterol and stigmasterol in Croton sublyratus proceeds via a mixed origin of isoprene units. Phytochemistry. 2003 Feb; 62(3):389-98. doi: 10.1016/s0031-9422(02)00555-1. [PMID: 12620352]
  • J Schwender, C Gemünden, H K Lichtenthaler. Chlorophyta exclusively use the 1-deoxyxylulose 5-phosphate/2-C-methylerythritol 4-phosphate pathway for the biosynthesis of isoprenoids. Planta. 2001 Feb; 212(3):416-23. doi: 10.1007/s004250000409. [PMID: 11289606]
  • W Eisenreich, F Rohdich, A Bacher. Deoxyxylulose phosphate pathway to terpenoids. Trends in plant science. 2001 Feb; 6(2):78-84. doi: 10.1016/s1360-1385(00)01812-4. [PMID: 11173292]
  • K P Adam, R Thiel, J Zapp. Incorporation of 1-[1-(13)C]Deoxy-D-xylulose in chamomile sesquiterpenes. Archives of biochemistry and biophysics. 1999 Sep; 369(1):127-32. doi: 10.1006/abbi.1999.1346. [PMID: 10462448]
  • M A Fellermeier, U H Maier, S Sagner, A Bacher, M H Zenk. (-)-2C-methyl-D-erythrono-1,4-lactone is formed after application of the terpenoid precursor 1-deoxy-D-xylulose. FEBS letters. 1998 Oct; 437(3):278-80. doi: 10.1016/s0014-5793(98)01250-2. [PMID: 9824307]
  • D Arigoni, S Sagner, C Latzel, W Eisenreich, A Bacher, M H Zenk. Terpenoid biosynthesis from 1-deoxy-D-xylulose in higher plants by intramolecular skeletal rearrangement. Proceedings of the National Academy of Sciences of the United States of America. 1997 Sep; 94(20):10600-5. doi: 10.1073/pnas.94.20.10600. [PMID: 9380681]
  • D L Garver, D M Davis, H Dekirmenjian, S Ericksen, L Gosenfeld, J Haraszti. Dystonic reactions following neuroleptics: time course and proposed mechanisms. Psychopharmacologia. 1976 May; 47(2):199-201. doi: 10.1007/bf00735822. [PMID: 5743]
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