N-Acetyl-4-O-acetylneuraminic acid (BioDeep_00000005375)

   

human metabolite Endogenous


代谢物信息卡片


(2S,4S,5R,6R)-4-(acetyloxy)-5-acetamido-2-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid

化学式: C13H21NO10 (351.1165)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(feces) 42.84%

分子结构信息

SMILES: CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)O)OC(=O)C
InChI: InChI=1S/C13H21NO10/c1-5(16)14-9-8(23-6(2)17)3-13(22,12(20)21)24-11(9)10(19)7(18)4-15/h7-11,15,18-19,22H,3-4H2,1-2H3,(H,14,16)(H,20,21)/t7-,8+,9-,10-,11-,13?/m1/s1

描述信息

N-Acetyl-4-O-acetylneuraminic acid is a component of glycoprotein- and glycolipid-bound sialic acids present in the human erythrocyte membrane (RBC). (PMID: 12527384) [HMDB]
N-Acetyl-4-O-acetylneuraminic acid is a component of glycoprotein- and glycolipid-bound sialic acids present in the human erythrocyte membrane (RBC). (PMID: 12527384).

同义名列表

14 个代谢物同义名

(2S,4S,5R,6R)-4-(acetyloxy)-5-acetamido-2-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid; 4-Acetate 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid; 4-Acetate 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonate; 4-Acetate 5-acetamido-3,5-dideoxy-D-glycero-D-galacto-nonulosonic acid; 4-Acetate 5-acetamido-3,5-dideoxy-D-glycero-D-galacto-nonulosonate; 5-N-Acetyl-4-O-acetyl-neuraminic acid; 4-O-Acetyl-N-acetylneuraminic acid; N-Acetyl-4-O-acetylneuraminic acid; N-Acetyl-4-O-acetylneuraminate; 4-O-Acetyl-N-acetylneuraminate; N,4-O-Diacetylneuraminic acid; N,4-O-Diacetylneuraminate; SCHEMBL13190783; Neu4,5ac2



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 NANS, NEU4, NPL, SPTAN1
Endosome membrane 1 TF
Endoplasmic reticulum membrane 1 NEU4
Mitochondrion membrane 1 NEU4
cytosol 3 NANS, NPL, SPTAN1
cell cortex 1 SPTAN1
cell junction 1 SPTAN1
cell surface 1 TF
mitochondrial inner membrane 1 NEU4
Lysosome 1 NEU4
plasma membrane 5 BCHE, F2, NEU4, SPTAN1, TF
Membrane 2 NEU4, SPTAN1
apical plasma membrane 1 TF
extracellular exosome 5 A2M, F2, NANS, SPTAN1, TF
extracellular space 4 A2M, BCHE, F2, TF
lysosomal lumen 1 NEU4
perinuclear region of cytoplasm 1 TF
intracellular membrane-bounded organelle 1 SPTAN1
Microsome membrane 1 NEU4
Secreted 4 A2M, BCHE, F2, TF
extracellular region 5 A2M, BCHE, F2, SPTAN1, TF
Mitochondrion outer membrane 1 NEU4
mitochondrial outer membrane 1 NEU4
basal part of cell 1 TF
Extracellular vesicle 1 SPTAN1
actin cytoskeleton 1 SPTAN1
cytoplasmic vesicle 1 TF
microtubule cytoskeleton 1 SPTAN1
Early endosome 1 TF
clathrin-coated pit 1 TF
recycling endosome 1 TF
vesicle 1 TF
Cytoplasm, cytoskeleton 1 SPTAN1
collagen-containing extracellular matrix 2 A2M, F2
Late endosome 1 TF
Cell projection, neuron projection 1 NEU4
neuron projection 1 NEU4
cell projection 1 SPTAN1
Cytoplasm, cell cortex 1 SPTAN1
blood microparticle 4 A2M, BCHE, F2, TF
basal plasma membrane 1 TF
secretory granule lumen 1 TF
HFE-transferrin receptor complex 1 TF
Golgi lumen 1 F2
endoplasmic reticulum lumen 3 BCHE, F2, TF
cortical actin cytoskeleton 1 SPTAN1
platelet alpha granule lumen 1 A2M
specific granule lumen 1 SPTAN1
tertiary granule lumen 1 SPTAN1
endocytic vesicle 1 TF
Lysosome lumen 1 NEU4
nuclear envelope lumen 1 BCHE
clathrin-coated endocytic vesicle membrane 1 TF
spectrin 1 SPTAN1
[Isoform 1]: Cell membrane 1 NEU4
vesicle coat 1 TF
[Isoform 2]: Mitochondrion inner membrane 1 NEU4
dense body 1 TF
organelle inner membrane 1 NEU4
organelle 1 SPTAN1


文献列表

  • M Iwersen, V Vandamme-Feldhaus, R Schauer. Enzymatic 4-O-acetylation of N-acetylneuraminic acid in guinea-pig liver. Glycoconjugate journal. 1998 Sep; 15(9):895-904. doi: 10.1023/a:1006911100081. [PMID: 10052593]