(S)-Ureidoglycolic acid (BioDeep_00000004454)
Secondary id: BioDeep_00001869386
human metabolite Endogenous
代谢物信息卡片
化学式: C3H6N2O4 (134.0328)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 10.76%
分子结构信息
SMILES: C(C(=O)O)(NC(=O)N)O
InChI: InChI=1S/C3H6N2O4/c4-3(9)5-1(6)2(7)8/h1,6H,(H,7,8)(H3,4,5,9)
描述信息
(S)-Ureidoglycolic acid is a substrate of enzyme ureidoglycolate dehydrogenase [EC 1.1.1.154] in purine metabolism pathway (KEGG). [HMDB]
(S)-Ureidoglycolic acid is a substrate of enzyme ureidoglycolate dehydrogenase [EC 1.1.1.154] in purine metabolism pathway (KEGG).
同义名列表
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:15412
- ChEBI: CHEBI:49050
- KEGG: C00603
- PubChem: 439269
- PubChem: 336
- HMDB: HMDB0001005
- Metlin: METLIN5935
- MetaCyc: CPD-1091
- KNApSAcK: C00007466
- foodb: FDB022364
- chemspider: 388403
- CAS: 10346-27-7
- CAS: 7424-03-5
- PMhub: MS000016914
- PubChem: 3878
- PDB-CCD: UGC
- 3DMET: B01292
- NIKKAJI: J1.344.912K
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
11 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- allantoin degradation to ureidoglycolate II (ammonia producing):
S-ureidoglycine + H2O ⟶ S-(-)-ureidoglycolate + H+ + ammonia
WikiPathways(0)
Plant Reactome(3)
- Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Amine and polyamine biosynthesis:
AGM + H2O ⟶ N-Carbamoylputrescine + ammonia - Allantoin assimilation:
H2O + S-(-)-Ureidoglycolate ⟶ ammonia + carbon dioxide + glyoxylate
INOH(1)
- Purine nucleotides and Nucleosides metabolism ( Purine nucleotides and Nucleosides metabolism ):
H2O + XTP ⟶ Pyrophosphate + XMP
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(6)
- Glycolate and Glyoxylate Degradation:
Allantoin ⟶ (S)-(+)-allantoin - Urate Degradation to Glyoxylate:
5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + Hydrogen Ion ⟶ Allantoin + Carbon dioxide - Glycolate and Glyoxylate Degradation:
Allantoin ⟶ (S)-(+)-allantoin - Allantoin Degradation (Anaerobic):
(S)-Ureidoglycolic acid + NADP ⟶ Hydrogen Ion + NADPH + Oxalureate - Urate Degradation to Ureidoglycolate:
5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + Hydrogen Ion ⟶ Allantoin + Carbon dioxide - Allantoin Degradation (Anaerobic):
Adenosine diphosphate + Carbamoyl phosphate + Hydrogen Ion ⟶ Adenosine triphosphate + Ammonium + Carbon dioxide
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Heike Riegler, Claudia Geserick, Rita Zrenner. Arabidopsis thaliana nucleosidase mutants provide new insights into nucleoside degradation.
The New phytologist.
2011 Jul; 191(2):349-359. doi:
10.1111/j.1469-8137.2011.03711.x. [PMID: 21599668] - Joe C Polacco, David L Hyten, Mônica Medeiros-Silva, David A Sleper, Kristin D Bilyeu. Mutational analysis of the major soybean UreF paralogue involved in urease activation.
Journal of experimental botany.
2011 Jun; 62(10):3599-608. doi:
10.1093/jxb/err054. [PMID: 21430294] - Peter E Larsen, Avinash Sreedasyam, Geetika Trivedi, Gopi K Podila, Leland J Cseke, Frank R Collart. Using next generation transcriptome sequencing to predict an ectomycorrhizal metabolome.
BMC systems biology.
2011 May; 5(?):70. doi:
10.1186/1752-0509-5-70. [PMID: 21569493] - Alfonso Muñoz, Gerard L Bannenberg, Olimpio Montero, Juan Miguel Cabello-Díaz, Pedro Piedras, Manuel Pineda. An alternative pathway for ureide usage in legumes: enzymatic formation of a ureidoglycolate adduct in Cicer arietinum and Phaseolus vulgaris.
Journal of experimental botany.
2011 Jan; 62(1):307-18. doi:
10.1093/jxb/erq268. [PMID: 20813786] - Fabio Serventi, Ileana Ramazzina, Ilaria Lamberto, Vincenzo Puggioni, Rita Gatti, Riccardo Percudani. Chemical basis of nitrogen recovery through the ureide pathway: formation and hydrolysis of S-ureidoglycine in plants and bacteria.
ACS chemical biology.
2010 Feb; 5(2):203-14. doi:
10.1021/cb900248n. [PMID: 20038185] - Andrea K Werner, Imogen A Sparkes, Tina Romeis, Claus-Peter Witte. Identification, biochemical characterization, and subcellular localization of allantoate amidohydrolases from Arabidopsis and soybean.
Plant physiology.
2008 Feb; 146(2):418-30. doi:
10.1104/pp.107.110809. [PMID: 18065556] - María José Raso, Alfonso Muñoz, Manuel Pineda, Pedro Piedras. Biochemical characterisation of an allantoate-degrading enzyme from French bean (Phaseolus vulgaris): the requirement of phenylhydrazine.
Planta.
2007 Oct; 226(5):1333-42. doi:
10.1007/s00425-007-0570-7. [PMID: 17594111] - Alfonso Muñoz, María José Raso, Manuel Pineda, Pedro Piedras. Degradation of ureidoglycolate in French bean (Phaseolus vulgaris) is catalysed by a ubiquitous ureidoglycolate urea-lyase.
Planta.
2006 Jun; 224(1):175-84. doi:
10.1007/s00425-005-0186-8. [PMID: 16333637] - Cheng Bai, Charles C Reilly, Bruce W Wood. Nickel deficiency disrupts metabolism of ureides, amino acids, and organic acids of young pecan foliage.
Plant physiology.
2006 Feb; 140(2):433-43. doi:
10.1104/pp.105.072983. [PMID: 16415214] - A Muñoz, P Piedras, M Aguilar, M Pineda. Urea is a product of ureidoglycolate degradation in chickpea. Purification and characterization of the ureidoglycolate urea-lyase.
Plant physiology.
2001 Feb; 125(2):828-34. doi:
10.1104/pp.125.2.828. [PMID: 11161040] - . .
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