Altersolanol A (BioDeep_00000003917)

   


代谢物信息卡片


1,2,3,4,8-pentahydroxy-6-methoxy-3-methyl-2,4-dihydro-1H-anthracene-9,10-dione

化学式: C16H16O8 (336.0845136)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 66.67%

分子结构信息

SMILES: CC1(C(C(C2=C(C1O)C(=O)C3=C(C2=O)C(=CC(=C3)OC)O)O)O)O
InChI: InChI=1S/C16H16O8/c1-16(23)14(21)10-9(13(20)15(16)22)12(19)8-6(11(10)18)3-5(24-2)4-7(8)17/h3-4,13-15,17,20-23H,1-2H3/t13-,14+,15+,16-/m0/s1

描述信息

CONFIDENCE isolated standard

同义名列表

2 个代谢物同义名

Altersolanol A; 1,2,3,4,8-pentahydroxy-6-methoxy-3-methyl-2,4-dihydro-1H-anthracene-9,10-dione



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hong Liu, Hui Wang, Xiao Lan Liao, Bida Gao, Xun Lu, Donghui Sun, Weijie Gong, Jie Zhong, Hongjian Zhu, Xianting Pan, Li Guo, Xing Wang Deng, Qian Zhou. Mycoviral gene integration converts a plant pathogenic fungus into a biocontrol agent. Proceedings of the National Academy of Sciences of the United States of America. 2022 12; 119(50):e2214096119. doi: 10.1073/pnas.2214096119. [PMID: 36469771]
  • Philip F Uzor, Weaam Ebrahim, Patience O Osadebe, Justina N Nwodo, Festus B Okoye, Werner E G Müller, Wenhan Lin, Zhen Liu, Peter Proksch. Metabolites from Combretum dolichopetalum and its associated endophytic fungus Nigrospora oryzae--Evidence for a metabolic partnership. Fitoterapia. 2015 Sep; 105(?):147-50. doi: 10.1016/j.fitote.2015.06.018. [PMID: 26136060]
  • P D Mishra, S A Verekar, S K Deshmukh, K S Joshi, H H Fiebig, G Kelter. Altersolanol A: a selective cytotoxic anthraquinone from a Phomopsis sp. Letters in applied microbiology. 2015 Apr; 60(4):387-91. doi: 10.1111/lam.12384. [PMID: 25534717]
  • Xue-Ming Zhou, Cai-Juan Zheng, Guang-Ying Chen, Xiao-Ping Song, Chang-Ri Han, Gao-Nan Li, Yan-Hui Fu, Wen-Hao Chen, Zhi-Gang Niu. Bioactive anthraquinone derivatives from the mangrove-derived fungus Stemphylium sp. 33231. Journal of natural products. 2014 Sep; 77(9):2021-8. doi: 10.1021/np500340y. [PMID: 25136754]
  • Phunlap Pompeng, Damrong Sommit, Nongluksna Sriubolmas, Nattaya Ngamrojanavanich, Kiminori Matsubara, Khanitha Pudhom. Antiangiogenetic effects of anthranoids from Alternaria sp., an endophytic fungus in a Thai medicinal plant Erythrina variegata. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2013 Jul; 20(10):918-22. doi: 10.1016/j.phymed.2013.03.019. [PMID: 23639188]
  • Marie-Hélène Teiten, Fabienne Mack, Abdessamad Debbab, Amal H Aly, Mario Dicato, Peter Proksch, Marc Diederich. Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity. Bioorganic & medicinal chemistry. 2013 Jul; 21(13):3850-8. doi: 10.1016/j.bmc.2013.04.024. [PMID: 23664494]
  • Abdessamad Debbab, Amal H Aly, Ruangelie Edrada-Ebel, Victor Wray, Werner E G Müller, Frank Totzke, Ute Zirrgiebel, Christoph Schächtele, Michael H G Kubbutat, Wen Han Lin, Mahjouba Mosaddak, Abdelhak Hakiki, Peter Proksch, Rainer Ebel. Bioactive metabolites from the endophytic fungus Stemphylium globuliferum isolated from Mentha pulegium. Journal of natural products. 2009 Apr; 72(4):626-31. doi: 10.1021/np8004997. [PMID: 19271717]