Isochorismic acid (BioDeep_00001868980)

Main id: BioDeep_00000004304

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Isochorismic acid

化学式: C10H10O6 (226.0477)
中文名称: （5S，6S）-5-[（1-羧基乙烯基）氧]-6-羟基-1,3-环己二烯-1-羧酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=C(C(=O)O)OC1C=CC=C(C1O)C(=O)O
InChI: InChI=1S/C10H10O6/c1-5(9(12)13)16-7-4-2-3-6(8(7)11)10(14)15/h2-4,7-8,11H,1H2,(H,12,13)(H,14,15)/t7-,8-/m0/s1

描述信息

同义名列表

3 个代谢物同义名

Isochorismic acid; Isochorismate; Isochorismic acid



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

24 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ARMC1, COASY, HSPB6, MAPK6, MAPKAPK3, NUDT6, RPS2, SGCG, TXN
Nucleus 10 HSPB6, MAPK6, MAPKAPK3, MYB, NSL1, NUDT6, NXN, RPS2, TCF19, TXN
cytosol 11 ARMC1, GSTK1, HSPB6, LIPE, MAPK6, MAPKAPK3, MYB, NSL1, NXN, RPS2, TXN
nucleoplasm 6 MAPK6, MAPKAPK3, MYB, NSL1, RPS2, TXN
RNA polymerase II transcription regulator complex 1 MYB
Cell membrane 2 LIPE, NPR3
sarcolemma 2 SGCD, SGCG
Cytoplasm, cytosol 2 LIPE, NXN
plasma membrane 5 CXCR5, NPR1, NPR3, SGCD, SGCG
Membrane 8 CXCR5, GSTK1, HRK, LIPE, MYB, NPR1, NPR3, RPS2
caveola 1 LIPE
extracellular exosome 5 COASY, GSTK1, NPR3, RPS2, TXN
mitochondrion 7 ARMC1, COASY, GSTK1, HRK, HSPB6, NSL1, NUDT6
protein-containing complex 2 MAPK6, NPR3
Single-pass type I membrane protein 1 NPR3
Secreted 2 HSPB6, TXN
extracellular region 2 HSPB6, TXN
Mitochondrion outer membrane 1 ARMC1
mitochondrial outer membrane 2 ARMC1, COASY
Mitochondrion matrix 1 COASY
mitochondrial matrix 2 COASY, GSTK1
external side of plasma membrane 1 CXCR5
Single-pass type II membrane protein 2 SGCD, SGCG
Cell membrane, sarcolemma 2 SGCD, SGCG
Cytoplasm, cytoskeleton 2 SGCD, SGCG
focal adhesion 1 RPS2
Peroxisome 1 GSTK1
sarcoplasmic reticulum 1 SGCD
peroxisomal matrix 1 GSTK1
nuclear speck 2 HSPB6, NSL1
receptor complex 1 NPR1
cytoskeleton 2 SGCD, SGCG
Nucleus, nucleolus 1 RPS2
spindle pole 1 NSL1
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Chromosome, centromere, kinetochore 1 NSL1
NSL complex 1 NSL1
MLL1 complex 1 NSL1
nuclear matrix 1 MYB
kinetochore 1 NSL1
outer kinetochore 1 NSL1
histone acetyltransferase complex 1 NSL1
dystrophin-associated glycoprotein complex 1 SGCD
sarcoglycan complex 2 SGCD, SGCG
cytosolic ribosome 1 RPS2
ribosome 1 RPS2
cytosolic small ribosomal subunit 1 RPS2
ANPR-A receptor complex 1 NPR1
small ribosomal subunit 1 RPS2
septin cytoskeleton 1 MAPK6
MIS12/MIND type complex 1 NSL1


文献列表

  • Wei Li, Jinyu He, Xiuzhuo Wang, Matthew Ashline, Zirui Wu, Fengquan Liu, Zheng Qing Fu, Ming Chang. PBS3: a versatile player in and beyond salicylic acid biosynthesis in Arabidopsis. The New phytologist. 2023 01; 237(2):414-422. doi: 10.1111/nph.18558. [PMID: 36263689]
  • Amna Mhamdi. Here, There, and Everywhere: Plastid- and Nuclear-Localized WHIRLY1 Regulates Salicylic Acid Homeostasis during Developmental Senescence. Plant physiology. 2020 12; 184(4):1620-1621. doi: 10.1104/pp.20.01475. [PMID: 33277328]
  • Michael P Torrens-Spence, Anastassia Bobokalonova, Valentina Carballo, Christopher M Glinkerman, Tomáš Pluskal, Amber Shen, Jing-Ke Weng. PBS3 and EPS1 Complete Salicylic Acid Biosynthesis from Isochorismate in Arabidopsis. Molecular plant. 2019 12; 12(12):1577-1586. doi: 10.1016/j.molp.2019.11.005. [PMID: 31760159]
  • Dmitrij Rekhter, Daniel Lüdke, Yuli Ding, Kirstin Feussner, Krzysztof Zienkiewicz, Volker Lipka, Marcel Wiermer, Yuelin Zhang, Ivo Feussner. Isochorismate-derived biosynthesis of the plant stress hormone salicylic acid. Science (New York, N.Y.). 2019 08; 365(6452):498-502. doi: 10.1126/science.aaw1720. [PMID: 31371615]
  • Yingjie Zhou, Johan Memelink, Huub J M Linthorst. An E. coli biosensor for screening of cDNA libraries for isochorismate pyruvate lyase-encoding cDNAs. Molecular genetics and genomics : MGG. 2018 Oct; 293(5):1181-1190. doi: 10.1007/s00438-018-1450-5. [PMID: 29796759]
  • Chao Chen, Yonghua Zhang, Pan Ye, Xiaofeng Ma, Chaoxing Zheng, Genfa Zhang. ENO2 knock-out mutants in Arabidopsis modify the regulation of the gene expression response to NaCl stress. Molecular biology reports. 2018 Oct; 45(5):1331-1338. doi: 10.1007/s11033-018-4292-7. [PMID: 30120651]
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  • Xiaoyan Wang, Jiong Gao, Zheng Zhu, Xianxin Dong, Xiaolei Wang, Guodong Ren, Xin Zhou, Benke Kuai. TCP transcription factors are critical for the coordinated regulation of isochorismate synthase 1 expression in Arabidopsis thaliana. The Plant journal : for cell and molecular biology. 2015 Apr; 82(1):151-62. doi: 10.1111/tpj.12803. [PMID: 25702611]
  • Hongbo Liu, Xianghua Li, Jinghua Xiao, Shiping Wang. A convenient method for simultaneous quantification of multiple phytohormones and metabolites: application in study of rice-bacterium interaction. Plant methods. 2012 Jan; 8(1):2. doi: 10.1186/1746-4811-8-2. [PMID: 22243810]
  • Veselin Dimitrov Petrov, Frank Van Breusegem. Hydrogen peroxide-a central hub for information flow in plant cells. AoB PLANTS. 2012; 2012(?):pls014. doi: 10.1093/aobpla/pls014. [PMID: 22708052]
  • Janick Mathys, Kaat De Cremer, Pieter Timmermans, Stefan Van Kerckhove, Bart Lievens, Mieke Vanhaecke, Bruno P A Cammue, Barbara De Coninck. Genome-Wide Characterization of ISR Induced in Arabidopsis thaliana by Trichoderma hamatum T382 Against Botrytis cinerea Infection. Frontiers in plant science. 2012; 3(?):108. doi: 10.3389/fpls.2012.00108. [PMID: 22661981]
  • Marcel C van Verk, John F Bol, Huub J M Linthorst. WRKY transcription factors involved in activation of SA biosynthesis genes. BMC plant biology. 2011 May; 11(?):89. doi: 10.1186/1471-2229-11-89. [PMID: 21595875]
  • Yun Lee, Fang Chen, Lina Gallego-Giraldo, Richard A Dixon, Eberhard O Voit. Integrative analysis of transgenic alfalfa (Medicago sativa L.) suggests new metabolic control mechanisms for monolignol biosynthesis. PLoS computational biology. 2011 May; 7(5):e1002047. doi: 10.1371/journal.pcbi.1002047. [PMID: 21625579]
  • Takashi Kadono, Daniel Tran, Rafik Errakhi, Takuya Hiramatsu, Patrice Meimoun, Joël Briand, Mari Iwaya-Inoue, Tomonori Kawano, François Bouteau. Increased anion channel activity is an unavoidable event in ozone-induced programmed cell death. PloS one. 2010 Oct; 5(10):e13373. doi: 10.1371/journal.pone.0013373. [PMID: 20967217]
  • Michael Bartsch, Paweł Bednarek, Pedro D Vivancos, Bernd Schneider, Edda von Roepenack-Lahaye, Christine H Foyer, Erich Kombrink, Dierk Scheel, Jane E Parker. Accumulation of isochorismate-derived 2,3-dihydroxybenzoic 3-O-beta-D-xyloside in arabidopsis resistance to pathogens and ageing of leaves. The Journal of biological chemistry. 2010 Aug; 285(33):25654-65. doi: 10.1074/jbc.m109.092569. [PMID: 20538606]
  • Junli Huang, Min Gu, Zhibing Lai, Baofang Fan, Kai Shi, Yan-Hong Zhou, Jing-Quan Yu, Zhixiang Chen. Functional analysis of the Arabidopsis PAL gene family in plant growth, development, and response to environmental stress. Plant physiology. 2010 Aug; 153(4):1526-38. doi: 10.1104/pp.110.157370. [PMID: 20566705]
  • Sejir Chaouch, Guillaume Queval, Sandy Vanderauwera, Amna Mhamdi, Michaël Vandorpe, Mathilde Langlois-Meurinne, Frank Van Breusegem, Patrick Saindrenan, Graham Noctor. Peroxisomal hydrogen peroxide is coupled to biotic defense responses by ISOCHORISMATE SYNTHASE1 in a daylength-related manner. Plant physiology. 2010 Aug; 153(4):1692-705. doi: 10.1104/pp.110.153957. [PMID: 20543092]
  • Giordano Rampioni, Christian Pustelny, Matthew P Fletcher, Victoria J Wright, Mary Bruce, Kendra P Rumbaugh, Stephan Heeb, Miguel Cámara, Paul Williams. Transcriptomic analysis reveals a global alkyl-quinolone-independent regulatory role for PqsE in facilitating the environmental adaptation of Pseudomonas aeruginosa to plant and animal hosts. Environmental microbiology. 2010 Jun; 12(6):1659-73. doi: 10.1111/j.1462-2920.2010.02214.x. [PMID: 20406282]
  • Xudong Zhang, Sixue Chen, Zhonglin Mou. Nuclear localization of NPR1 is required for regulation of salicylate tolerance, isochorismate synthase 1 expression and salicylate accumulation in Arabidopsis. Journal of plant physiology. 2010 Jan; 167(2):144-8. doi: 10.1016/j.jplph.2009.08.002. [PMID: 19716624]
  • Zhixiang Chen, Zuyu Zheng, Junli Huang, Zhibing Lai, Baofang Fan. Biosynthesis of salicylic acid in plants. Plant signaling & behavior. 2009 Jun; 4(6):493-6. doi: 10.4161/psb.4.6.8392. [PMID: 19816125]
  • Rachel A Okrent, Matthew D Brooks, Mary C Wildermuth. Arabidopsis GH3.12 (PBS3) conjugates amino acids to 4-substituted benzoates and is inhibited by salicylate. The Journal of biological chemistry. 2009 Apr; 284(15):9742-54. doi: 10.1074/jbc.m806662200. [PMID: 19189963]
  • Maria Elizabeth Abreu, Sergi Munné-Bosch. Salicylic acid deficiency in NahG transgenic lines and sid2 mutants increases seed yield in the annual plant Arabidopsis thaliana. Journal of experimental botany. 2009; 60(4):1261-71. doi: 10.1093/jxb/ern363. [PMID: 19188277]
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  • Christopher T Defraia, Eric A Schmelz, Zhonglin Mou. A rapid biosensor-based method for quantification of free and glucose-conjugated salicylic acid. Plant methods. 2008 Dec; 4(?):28. doi: 10.1186/1746-4811-4-28. [PMID: 19117519]
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  • Marcus A Strawn, Sharon K Marr, Kentaro Inoue, Noriko Inada, Chloe Zubieta, Mary C Wildermuth. Arabidopsis isochorismate synthase functional in pathogen-induced salicylate biosynthesis exhibits properties consistent with a role in diverse stress responses. The Journal of biological chemistry. 2007 Feb; 282(8):5919-33. doi: 10.1074/jbc.m605193200. [PMID: 17190832]
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