Exact Mass: 495.1965
Exact Mass Matches: 495.1965
Found 500 metabolites which its exact mass value is equals to given mass value 495.1965
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Isometamidium chloride
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent
Morphine dinicotinate
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics
(9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, methyl ester
Ala Tyr Asn Glu
Thr Asn Phe Asp
KT5823
D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors
Ala Asp Gln Tyr
Ala Asp Tyr Gln
Ala Glu Asn Tyr
Ala Glu Tyr Asn
Ala Gly Trp Tyr
Ala Gly Tyr Trp
Ala Asn Glu Tyr
Ala Asn Tyr Glu
Ala Gln Asp Tyr
Ala Gln Tyr Asp
Ala Trp Gly Tyr
Ala Trp Tyr Gly
Ala Tyr Asp Gln
Ala Tyr Glu Asn
Ala Tyr Gly Trp
Ala Tyr Gln Asp
Ala Tyr Trp Gly
Cys Asp Lys Met
Cys Asp Met Lys
Cys Phe Asn Leu
Cys Phe Gln Val
Cys Phe Val Gln
Cys Ile Phe Asn
Cys Ile Asn Phe
Cys Lys Asp Met
Cys Lys Met Asp
Cys Leu Phe Asn
Cys Leu Asn Phe
Cys Met Asp Lys
Cys Met Lys Asp
Cys Met Arg Ser
Cys Met Ser Arg
Cys Asn Phe Ile
Cys Asn Phe Leu
Cys Asn Ile Phe
Cys Asn Leu Phe
Cys Asn Pro Tyr
Cys Asn Tyr Pro
Cys Pro Asn Tyr
Cys Pro Tyr Asn
Cys Gln Phe Val
Cys Gln Val Phe
Cys Arg Met Ser
Cys Arg Ser Met
Cys Ser Met Arg
Cys Ser Arg Met
Cys Ser Thr Trp
Cys Ser Trp Thr
Cys Thr Ser Trp
Cys Thr Trp Ser
Cys Val Phe Gln
Cys Val Gln Phe
Cys Trp Ser Thr
Cys Trp Thr Ser
Cys Tyr Asn Pro
Cys Tyr Pro Asn
Asp Ala Gln Tyr
Asp Ala Tyr Gln
Asp Cys Lys Met
Asp Cys Met Lys
Asp Phe Asn Thr
Asp Phe Gln Ser
Asp Phe Ser Gln
Asp Phe Thr Asn
Asp His Pro Gln
Asp His Gln Pro
Asp Lys Cys Met
Asp Lys Met Cys
Asp Met Cys Lys
Asp Met Lys Cys
Asp Asn Phe Thr
Asp Asn Thr Phe
Asp Pro His Gln
Asp Pro Gln His
Asp Gln Ala Tyr
Asp Gln Phe Ser
Asp Gln His Pro
Asp Gln Pro His
Asp Gln Ser Phe
Asp Gln Tyr Ala
Asp Ser Phe Gln
Asp Ser Gln Phe
Asp Thr Phe Asn
Asp Thr Asn Phe
Asp Tyr Ala Gln
Asp Tyr Gln Ala
Glu Ala Asn Tyr
Glu Ala Tyr Asn
Glu Phe Asn Ser
Glu Phe Ser Asn
Glu Gly Gln Tyr
Glu Gly Tyr Gln
Glu His Asn Pro
Glu His Pro Asn
Glu Asn Ala Tyr
Glu Asn Phe Ser
Glu Asn His Pro
Glu Asn Pro His
Glu Asn Ser Phe
Glu Asn Tyr Ala
Glu Pro His Asn
Glu Pro Asn His
Glu Gln Gly Tyr
Glu Gln Tyr Gly
Glu Ser Phe Asn
Glu Ser Asn Phe
Glu Tyr Ala Asn
Glu Tyr Gly Gln
Glu Tyr Asn Ala
Glu Tyr Gln Gly
Phe Ala Met Gln
Phe Ala Gln Met
Phe Cys Ile Asn
Phe Cys Leu Asn
Phe Cys Asn Ile
Phe Cys Asn Leu
Phe Cys Gln Val
Phe Cys Val Gln
Phe Asp Asn Thr
Phe Asp Gln Ser
Phe Asp Ser Gln
Phe Asp Thr Asn
Phe Glu Asn Ser
Phe Glu Ser Asn
Phe Gly Ser Trp
Phe Gly Trp Ser
Phe Ile Cys Asn
Phe Ile Asn Cys
Phe Leu Cys Asn
Phe Leu Asn Cys
Phe Met Ala Gln
Phe Met Gln Ala
Phe Asn Cys Ile
Phe Asn Cys Leu
Phe Asn Asp Thr
Phe Asn Glu Ser
Phe Asn Ile Cys
Phe Asn Leu Cys
Phe Asn Ser Glu
Phe Asn Thr Asp
Phe Gln Ala Met
Phe Gln Cys Val
Phe Gln Asp Ser
Phe Gln Met Ala
Phe Gln Ser Asp
Phe Gln Val Cys
Phe Ser Asp Gln
Phe Ser Glu Asn
Phe Ser Gly Trp
Phe Ser Asn Glu
Phe Ser Gln Asp
Phe Ser Trp Gly
Phe Thr Asp Asn
Phe Thr Asn Asp
Phe Val Cys Gln
Phe Val Gln Cys
Phe Trp Gly Ser
Phe Trp Ser Gly
Gly Ala Trp Tyr
Gly Ala Tyr Trp
Gly Glu Gln Tyr
Gly Glu Tyr Gln
Gly Phe Ser Trp
Gly Phe Trp Ser
Gly Gln Glu Tyr
Gly Gln Tyr Glu
Gly Ser Phe Trp
Gly Ser Trp Phe
Gly Trp Ala Tyr
Gly Trp Phe Ser
Gly Trp Ser Phe
Gly Trp Tyr Ala
Gly Tyr Ala Trp
Gly Tyr Glu Gln
Gly Tyr Gln Glu
Gly Tyr Trp Ala
His Asp Pro Gln
His Asp Gln Pro
His Glu Asn Pro
His Glu Pro Asn
His Asn Glu Pro
His Asn Pro Glu
His Pro Asp Gln
His Pro Glu Asn
His Pro Asn Glu
His Pro Gln Asp
His Gln Asp Pro
His Gln Pro Asp
Ile Cys Phe Asn
Ile Cys Asn Phe
Ile Phe Cys Asn
Ile Phe Asn Cys
Ile Asn Cys Phe
Ile Asn Phe Cys
Lys Cys Asp Met
Lys Cys Met Asp
Lys Asp Cys Met
Lys Asp Met Cys
Lys Met Cys Asp
Lys Met Asp Cys
Leu Cys Phe Asn
Leu Cys Asn Phe
Leu Phe Cys Asn
Leu Phe Asn Cys
Leu Asn Cys Phe
Leu Asn Phe Cys
Met Ala Phe Gln
Met Ala Gln Phe
Met Cys Asp Lys
Met Cys Lys Asp
Met Cys Arg Ser
Met Cys Ser Arg
Met Asp Cys Lys
Met Asp Lys Cys
Met Phe Ala Gln
Met Phe Gln Ala
Met Lys Cys Asp
Met Lys Asp Cys
Met Met Asn Thr
Met Met Gln Ser
Met Met Ser Gln
Met Met Thr Asn
Met Asn Met Thr
Met Asn Thr Met
Met Gln Ala Phe
Met Gln Phe Ala
Met Gln Met Ser
Met Gln Ser Met
Met Arg Cys Ser
Met Arg Ser Cys
Met Ser Cys Arg
Met Ser Met Gln
Met Ser Gln Met
Met Ser Arg Cys
Met Thr Met Asn
Met Thr Asn Met
Asn Ala Glu Tyr
Asn Ala Tyr Glu
Asn Cys Phe Ile
Asn Cys Phe Leu
Asn Cys Ile Phe
Asn Cys Leu Phe
Asn Cys Pro Tyr
Asn Cys Tyr Pro
Asn Asp Phe Thr
Asn Asp Thr Phe
Asn Glu Ala Tyr
Asn Glu Phe Ser
Asn Glu His Pro
Asn Glu Pro His
Asn Glu Ser Phe
Asn Glu Tyr Ala
Asn Phe Cys Ile
Asn Phe Cys Leu
Asn Phe Asp Thr
Asn Phe Glu Ser
Asn Phe Ser Glu
Asn Phe Thr Asp
Asn His Glu Pro
Asn His Pro Glu
Asn Met Met Thr
Asn Met Thr Met
Asn Pro Cys Tyr
Asn Pro Glu His
Asn Pro His Glu
Asn Pro Tyr Cys
Asn Ser Glu Phe
Asn Ser Phe Glu
Asn Thr Asp Phe
Asn Thr Phe Asp
Asn Thr Met Met
Asn Tyr Ala Glu
Asn Tyr Cys Pro
Asn Tyr Glu Ala
Asn Tyr Pro Cys
Pro Cys Asn Tyr
Pro Cys Tyr Asn
Pro Asp His Gln
Pro Asp Gln His
Pro Glu His Asn
Pro Glu Asn His
Pro His Asp Gln
Pro His Glu Asn
Pro His Asn Glu
Pro His Gln Asp
Pro Asn Cys Tyr
Pro Asn Glu His
Pro Asn His Glu
Pro Asn Tyr Cys
Pro Gln Asp His
Pro Gln His Asp
Pro Tyr Cys Asn
Pro Tyr Asn Cys
Gln Ala Asp Tyr
Gln Ala Tyr Asp
Gln Asp Ala Tyr
Gln Asp Phe Ser
Gln Asp His Pro
Gln Asp Pro His
Gln Asp Ser Phe
Gln Asp Tyr Ala
Gln Glu Gly Tyr
Gln Glu Tyr Gly
Gln Phe Asp Ser
Gln Phe Ser Asp
Gln Gly Glu Tyr
Gln Gly Tyr Glu
Gln His Asp Pro
Gln His Pro Asp
Gln Met Met Ser
Gln Met Ser Met
Gln Pro Asp His
Gln Pro His Asp
Gln Ser Asp Phe
Gln Ser Phe Asp
Gln Ser Met Met
Gln Tyr Ala Asp
Gln Tyr Asp Ala
Gln Tyr Glu Gly
Gln Tyr Gly Glu
Arg Cys Met Ser
Arg Cys Ser Met
Arg Met Cys Ser
Arg Met Ser Cys
Arg Ser Cys Met
Arg Ser Met Cys
Ser Cys Met Arg
Ser Cys Arg Met
Ser Cys Thr Trp
Ser Cys Trp Thr
Ser Asp Phe Gln
Ser Asp Gln Phe
Ser Glu Phe Asn
Ser Glu Asn Phe
Ser Phe Asp Gln
Ser Phe Glu Asn
Ser Phe Gly Trp
Ser Phe Asn Glu
Ser Phe Gln Asp
Ser Phe Trp Gly
Ser Gly Phe Trp
Ser Gly Trp Phe
Ser Met Cys Arg
Ser Met Met Gln
Ser Met Gln Met
Ser Met Arg Cys
Ser Asn Glu Phe
Ser Asn Phe Glu
Ser Gln Asp Phe
Ser Gln Phe Asp
Ser Gln Met Met
Ser Arg Cys Met
Ser Arg Met Cys
Ser Thr Cys Trp
Ser Thr Trp Cys
Ser Trp Cys Thr
Ser Trp Phe Gly
Ser Trp Gly Phe
Ser Trp Thr Cys
Thr Cys Ser Trp
Thr Cys Trp Ser
Thr Asp Phe Asn
Thr Asp Asn Phe
Thr Phe Asp Asn
Thr Phe Asn Asp
Thr Met Met Asn
Thr Met Asn Met
Thr Asn Asp Phe
Thr Asn Met Met
Thr Ser Cys Trp
Thr Ser Trp Cys
Thr Trp Cys Ser
Thr Trp Ser Cys
Trp Ala Gly Tyr
Trp Ala Tyr Gly
Trp Cys Ser Thr
Trp Cys Thr Ser
Trp Phe Gly Ser
Trp Phe Ser Gly
Trp Gly Ala Tyr
Trp Gly Phe Ser
Trp Gly Ser Phe
Trp Gly Tyr Ala
Trp Ser Cys Thr
Trp Ser Phe Gly
Trp Ser Gly Phe
Trp Ser Thr Cys
Trp Thr Cys Ser
Trp Thr Ser Cys
Trp Tyr Ala Gly
Trp Tyr Gly Ala
Tyr Ala Asp Gln
Tyr Ala Glu Asn
Tyr Ala Gly Trp
Tyr Ala Asn Glu
Tyr Ala Gln Asp
Tyr Ala Trp Gly
Tyr Cys Asn Pro
Tyr Cys Pro Asn
Tyr Asp Ala Gln
Tyr Asp Gln Ala
Tyr Glu Ala Asn
Tyr Glu Gly Gln
Tyr Glu Asn Ala
Tyr Glu Gln Gly
Tyr Gly Ala Trp
Tyr Gly Glu Gln
Tyr Gly Gln Glu
Tyr Gly Trp Ala
Tyr Asn Ala Glu
Tyr Asn Cys Pro
Tyr Asn Glu Ala
Tyr Asn Pro Cys
Tyr Pro Cys Asn
Tyr Pro Asn Cys
Tyr Gln Ala Asp
Tyr Gln Asp Ala
Tyr Gln Glu Gly
Tyr Gln Gly Glu
Tyr Trp Ala Gly
Tyr Trp Gly Ala
KT 5823
Nicomorphine
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids N - Nervous system > N02 - Analgesics > N02A - Opioids > N02AA - Natural opium alkaloids D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist D002491 - Central Nervous System Agents > D000700 - Analgesics
benzene,9-[fluoren-9-ylidene(phenyl)methyl]fluorene
2-Methyl-5-[(4-phenyl-1-piperazinyl)-(3,4,5-trimethoxyphenyl)methyl]-6-thiazolo[3,2-b][1,2,4]triazolol
(2S,3R,4S,5S,6R)-2-[(1S,2R,5S,6S)-2,6-dihydroxy-3-(hydroxymethyl)-5-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]cyclohex-3-en-1-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
Isometamidium chloride
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C250 - Antihelminthic Agent
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2-[[2-(1-oxoisoquinolin-2-yl)acetyl]amino]acetamide
2-[4-[4-(4-Fluorophenyl)-2-thiazolyl]-1-piperazinyl]-1-[4-(4-methoxyphenyl)-1-piperazinyl]ethanone
1-[[2-(3-chlorophenyl)-5-methyl-4-oxazolyl]methyl]-N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-3-piperidinecarboxamide
1-[(2S,3R,6S)-6-[2-(4-cyclohexyl-1-triazolyl)ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-(3,4-dichlorophenyl)urea
1-[(2R,3R,6R)-6-[2-(4-cyclohexyl-1-triazolyl)ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-(3,4-dichlorophenyl)urea
1-[(2S,3S,6R)-6-[2-(4-cyclohexyl-1-triazolyl)ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-(3,4-dichlorophenyl)urea
N-[[(2R,3R)-9-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N-methyl-2-thiophenesulfonamide
N-[[(2S,3R)-9-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N-methyl-2-thiophenesulfonamide
N-[[(2R,3R)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N-methyl-2-thiophenesulfonamide
N-[(5S,6R,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(3,3,3-trifluoropropyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
N-[(5S,6S,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(3,3,3-trifluoropropyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
N-[(5R,6R,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(3,3,3-trifluoropropyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
1-[(2S,3R,6R)-6-[2-(4-cyclohexyl-1-triazolyl)ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-(3,4-dichlorophenyl)urea
1-[(2S,3S,6S)-6-[2-(4-cyclohexyl-1-triazolyl)ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-(3,4-dichlorophenyl)urea
2-[(2R,5R,6S)-5-[[(2,5-difluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(4-phenylphenyl)acetamide
2-[(2R,5S,6S)-5-[[(2,5-difluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(4-phenylphenyl)acetamide
4-[(3aR,4R,9bR)-4-(hydroxymethyl)-1-[(1-methyl-4-imidazolyl)sulfonyl]-2,3,3a,4,5,9b-hexahydropyrrolo[3,2-c]quinolin-8-yl]-N,N-dimethylbenzamide
4-[(3aS,4R,9bS)-4-(hydroxymethyl)-1-[(1-methyl-4-imidazolyl)sulfonyl]-2,3,3a,4,5,9b-hexahydropyrrolo[3,2-c]quinolin-8-yl]-N,N-dimethylbenzamide
N-[[(2S,3S)-9-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N-methyl-2-thiophenesulfonamide
N-[[(2S,3S)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N-methyl-2-thiophenesulfonamide
N-[[(2R,3S)-9-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N-methyl-2-thiophenesulfonamide
N-[[(2S,3R)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N-methyl-2-thiophenesulfonamide
N-[(5S,6R,9S)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(3,3,3-trifluoropropyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
N-[(5R,6S,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(3,3,3-trifluoropropyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
N-[(5R,6R,9S)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(3,3,3-trifluoropropyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
N-[(5R,6S,9S)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(3,3,3-trifluoropropyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]methanesulfonamide
1-[(2R,3S,6R)-6-[2-(4-cyclohexyl-1-triazolyl)ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-(3,4-dichlorophenyl)urea
1-[(2R,3S,6S)-6-[2-(4-cyclohexyl-1-triazolyl)ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-(3,4-dichlorophenyl)urea
1-[(2R,3R,6S)-6-[2-(4-cyclohexyl-1-triazolyl)ethyl]-2-(hydroxymethyl)-3-oxanyl]-3-(3,4-dichlorophenyl)urea
2-[(2S,5R,6S)-5-[[(2,5-difluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(4-phenylphenyl)acetamide
2-[(2R,5S,6R)-5-[[(2,5-difluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(4-phenylphenyl)acetamide
2-[(2S,5S,6S)-5-[[(2,5-difluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(4-phenylphenyl)acetamide
2-[(2R,5R,6R)-5-[[(2,5-difluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(4-phenylphenyl)acetamide
2-[(2S,5R,6R)-5-[[(2,5-difluoroanilino)-oxomethyl]amino]-6-(hydroxymethyl)-2-oxanyl]-N-(4-phenylphenyl)acetamide
4-[(3aR,4S,9bR)-4-(hydroxymethyl)-1-[(1-methyl-4-imidazolyl)sulfonyl]-2,3,3a,4,5,9b-hexahydropyrrolo[3,2-c]quinolin-8-yl]-N,N-dimethylbenzamide
4-[(3aS,4S,9bS)-4-(hydroxymethyl)-1-[(1-methyl-4-imidazolyl)sulfonyl]-2,3,3a,4,5,9b-hexahydropyrrolo[3,2-c]quinolin-8-yl]-N,N-dimethylbenzamide
(1S,9R,10R,11R)-N-(1,3-benzodioxol-5-ylmethyl)-10-(hydroxymethyl)-12-(2-methoxyacetyl)-6-oxo-5-[(Z)-prop-1-enyl]-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
(1R,9S,10S,11S)-N-(1,3-benzodioxol-5-ylmethyl)-10-(hydroxymethyl)-12-(2-methoxyacetyl)-6-oxo-5-[(Z)-prop-1-enyl]-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
Anti-inflammatory agent 35
Anti-inflammatory agent 35 (compound 5a27) is an orally active curcumin analogue with anti-inflammatory activity. Anti-inflammatory agent 35 blocks mitogen-activated protein kinase (MAPK) signaling and p65 nuclear translocation of NF-kB. Anti-inflammatory agent 35 also inhibits yellow neutrophil infiltration and pro-inflammatory cytokine production. Anti-inflammatory agent 35 significantly attenuates lipopolysaccharide (LPS)-induced acute lung injury (ALI) in vivo[1].