Chemical Formula: C27H29NO8

Chemical Formula C27H29NO8

Found 1 metabolite its formula value is C27H29NO8

Anti-inflammatory agent 35

Anti-inflammatory agent 35

C27H29NO8 (495.1893074)


Anti-inflammatory agent 35 (compound 5a27) is an orally active curcumin analogue with anti-inflammatory activity. Anti-inflammatory agent 35 blocks mitogen-activated protein kinase (MAPK) signaling and p65 nuclear translocation of NF-kB. Anti-inflammatory agent 35 also inhibits yellow neutrophil infiltration and pro-inflammatory cytokine production. Anti-inflammatory agent 35 significantly attenuates lipopolysaccharide (LPS)-induced acute lung injury (ALI) in vivo[1].