Exact Mass: 381.0841964

Exact Mass Matches: 381.0841964

Found 205 metabolites which its exact mass value is equals to given mass value 381.0841964, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Metsulfuron-methyl

Benzoic acid, 2-(((((4-methoxy-6-methyl-1,3,5-triazin-2- yl)methylamino)carbonyl)amino)sulfonyl)-, methyl ester

C14H15N5O6S (381.07430100000005)


CONFIDENCE standard compound; EAWAG_UCHEM_ID 128

   

Celecoxib

4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide

C17H14F3N3O2S (381.07587800000005)


Celecoxib (INN) is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. It is marketed by Pfizer under the brand name Celebrex. In some countries, it is branded Celebra. Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. Celecoxib is a highly selective COX-2 inhibitor and primarily inhibits this isoform of cyclooxygenase, whereas traditional NSAIDs inhibit both COX-1 and COX-2. Celecoxib is approximately 10-20 times more selective for COX-2 inhibition over COX-1. In theory, this specificity allows celecoxib and other COX-2 inhibitors to reduce inflammation (and pain) while minimizing gastrointestinal adverse drug reactions (e.g. stomach ulcers) that are common with non-selective NSAIDs. It also means that it has a reduced effect on platelet aggregation compared to traditional NSAIDs; Celecoxib is a highly selective COX-2 inhibitor and primarily inhibits this isoform of cyclooxygenase, whereas traditional NSAIDs inhibit both COX-1 and COX-2. Celecoxib is approximately 10-20 times more selective for COX-2 inhibition over COX-1. In theory, this specificity allows celecoxib and other COX-2 inhibitors to reduce inflammation (and pain) while minimizing gastrointestinal adverse drug reactions (e.g. stomach ulcers) that are common with non-selective NSAIDs. It also means that it has a reduced effect on platelet aggregation compared to traditional NSAIDs. Celecoxib (INN) is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. It is marketed by Pfizer under the brand name Celebrex. In some countries, it is branded Celebra.; Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. CONFIDENCE standard compound; INTERNAL_ID 454; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4913; ORIGINAL_PRECURSOR_SCAN_NO 4912 CONFIDENCE standard compound; INTERNAL_ID 454; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4904; ORIGINAL_PRECURSOR_SCAN_NO 4902 INTERNAL_ID 454; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4913; ORIGINAL_PRECURSOR_SCAN_NO 4912 CONFIDENCE standard compound; INTERNAL_ID 454; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4877; ORIGINAL_PRECURSOR_SCAN_NO 4875 CONFIDENCE standard compound; INTERNAL_ID 454; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4898; ORIGINAL_PRECURSOR_SCAN_NO 4896 CONFIDENCE standard compound; INTERNAL_ID 454; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4899; ORIGINAL_PRECURSOR_SCAN_NO 4897 M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AH - Coxibs D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors D004791 - Enzyme Inhibitors > D016861 - Cyclooxygenase Inhibitors > D052246 - Cyclooxygenase 2 Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor > C80509 - COX-2 Inhibitor COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor CONFIDENCE standard compound; INTERNAL_ID 8516 CONFIDENCE standard compound; INTERNAL_ID 2356 D000893 - Anti-Inflammatory Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

4-Hydroxy-6-methylpretetramide

1,3,4,10,11,12-Hexahydroxy-6-methyltetracene-2-carboxamide

C20H15NO7 (381.084848)


A member of the class of pretetramides that is 6-methyltetracene-2-carboxamide carrying six hydroxy substituents at positions 1, 3, 4, 10, 11 and 12.

   

F5231

N-[2-chloro-4-fluoro-5-[4-(3-fluoropropyl)-5-oxotetrazol-1-yl]phenyl]ethanesulfonamide

C12H14ClF2N5O3S (381.0473908)


   

2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

C10H16N5O9P (381.0685616)


   

8-desmethylnovobiocic acid

8-desmethylnovobiocic acid

C21H19NO6 (381.12123140000006)


A hydroxycoumarin that is novobiocic acid lacking the 8-methyl group.

   

Rabeprazole sodium

Rabeprazole sodium

C18H20N3NaO3S (381.1123010000001)


C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent > C29723 - Proton Pump Inhibitor D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents D004791 - Enzyme Inhibitors > D054328 - Proton Pump Inhibitors

   

Desacetycefapirin

7-{[1-hydroxy-2-(pyridin-4-ylsulphanyl)ethylidene]amino}-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

C15H15N3O5S2 (381.04531)


Desacetycefapirin is a potential milk contaminant arising from the metabolism of cefapirin in cattle. D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams Potential milk contaminant arising from the metabolism of cefapirin in cattle

   

Oxopurpureine

4,5,14,15,16-pentamethoxy-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2,4,6,9,11,13(17),14-octaen-8-one

C21H19NO6 (381.12123140000006)


Oxopurpureine is found in beverages. Oxopurpureine is an alkaloid from the stems and leaves of Annona purpurea (soncoya). Alkaloid from the stems and leaves of Annona purpurea (soncoya). Oxopurpureine is found in beverages and fruits.

   

N-Acetyl-9-O-lactoylneuraminic acid

(2S,4S,5R,6R)-6-[(1R,2R)-1,2-Dihydroxy-3-[(2-hydroxypropanoyl)oxy]propyl]-2,4-dihydroxy-5-[(1-hydroxyethylidene)amino]oxane-2-carboxylate

C14H23NO11 (381.1271048)


N-Acetyl-9-O-lactoylneuraminic acid is a sialic acid produced by sialate 9-O-lactoyltransferases. Lactoylation of CMP-N-acetylneuraminic acid, N-acetylneuramimic acid and glycoconjugate-bound N-acetylneuramimic acid has been observed, with the glycoconjugate form being the best substrate. A sialic acid produced by sialate 9-O-lactoyltransferases. Lactoylation of CMP-N-acetylneuraminic acid, N-acetylneuramimic acid and glycoconjugate-bound N-acetylneuramimic acid has been observed, with the glycoconjugate form being the best substrate. [HMDB]

   

dehydrofelodipine

3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate

C18H17Cl2NO4 (381.0534582000001)


dehydrofelodipine is a metabolite of felodipine. Felodipine is a calcium channel blocker (calcium antagonist), a drug used to control hypertension (high blood pressure). It is marketed under the brand name Plendil by AstraZeneca and Renedil by Sanofi-Aventis. The formulation patent for the substance expired in 2007. AstraZeneca dropped Plendil from its support and AZ&Me free Rx access program in October 2008. (Wikipedia)

   

Seminaphtharhodafluor

2-amino-9-hydroxy-3H-12-oxaspiro[2-benzofuran-1,5-tetraphene]-3-one

C24H15NO4 (381.10010300000005)


   

4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide

4-(2,6-Dichlorobenzoylamino)-1H-pyrazole-3-carboxylic acid N-(piperidin-4-yl)amide

C16H17Cl2N5O2 (381.07592420000003)


C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C2185 - Cyclin-Dependent Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent COVID info from PDB, Protein Data Bank Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

Pyridine, 4-(5-((1R)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4H-1,2,4-triazol-3-yl)-

Pyridine, 4-(5-((1R)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4H-1,2,4-triazol-3-yl)-

C19H16ClN5O2 (381.0992466)


   

Cimicoxib

4-[4-chloro-5-(3-fluoro-4-methoxyphenyl)-1H-imidazol-1-yl]benzene-1-sulfonamide

C16H13ClFN3O3S (381.03501500000004)


C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor

   

Lavendustin A

5-{[(2,5-dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino}-2-hydroxybenzoic acid

C21H19NO6 (381.12123140000006)


C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor D004791 - Enzyme Inhibitors

   

Netoglitazone

5-({6-[(2-fluorophenyl)methoxy]naphthalen-2-yl}methyl)-1,3-thiazolidine-2,4-dione

C21H16FNO3S (381.08348780000006)


C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C98241 - Thiazolidinedione Antidiabetic Agent Netoglitazone is a dual agonist of PPARα and PPARγ with antihyperglycemic activity[1].

   

(5Z)-5-[[4-[(1-Pyridin-2-ylpyrrolidin-2-yl)methoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione

(5Z)-5-[[4-[(1-Pyridin-2-ylpyrrolidin-2-yl)methoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione

C20H19N3O3S (381.11470640000005)


   

Pleconaril

3-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole

C18H18F3N3O3 (381.13001940000004)


J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C254 - Anti-Infective Agent > C281 - Antiviral Agent

   

2-(4-(2-((3,5-Dichlorophenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanoic acid

2-(4-{[(3,5-dichlorophenyl)-C-hydroxycarbonimidoyl]methyl}phenoxy)-2-methylpropanoate

C18H17Cl2NO4 (381.0534582000001)


   

5-[[6-[(2-Fluorophenyl)methoxy]naphthalen-2-yl]methyl]-4-hydroxy-3H-1,3-thiazol-2-one

5-({6-[(2-fluorophenyl)methoxy]naphthalen-2-yl}methyl)-4-hydroxy-2,3-dihydro-1,3-thiazol-2-one

C21H16FNO3S (381.08348780000006)


   

Arnottianamide

Formamide, N-(6-(2-hydroxy-3,4-dimethoxyphenyl)naphtho(2,3-d)-1,3-dioxol-5-yl)-N-methyl-

C21H19NO6 (381.12123140000006)


   
   
   

Turraeanthin A

10-O-demethyl-17-O-methyl isoarnottianamide

C21H19NO6 (381.12123140000006)


   

6-Oxocorynoline

13-Methyl-6-oxochelidonine

C21H19NO6 (381.12123140000006)


   
   

Potassium lespedezate

Potassium lespedezate

C15H18KO9+ (381.0587858)


   
   
   
   

Glutamyl-S-(C3H7S)-cysteinylglycine

Glutamyl-S-(C3H7S)-cysteinylglycine

C13H23N3O6S2 (381.10282179999996)


Annotation level-3

   

Lavendustin A

Lavendustin A

C21H19NO6 (381.12123140000006)


C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor D004791 - Enzyme Inhibitors

   

10-O-demethyl-12-O-methylarnottianamide

10-O-demethyl-12-O-methylarnottianamide

C21H19NO6 (381.12123140000006)


   

(+/-)-pictonamine|13-deoxy-chilenine methyl enol ether|9,10,13-trimethoxy-5,6-dihydro-[1,3]dioxolo[4,5:4,5]benzo[1,2:4,5]azepino[2,1-a]isoindol-8-one|Pictonamine

(+/-)-pictonamine|13-deoxy-chilenine methyl enol ether|9,10,13-trimethoxy-5,6-dihydro-[1,3]dioxolo[4,5:4,5]benzo[1,2:4,5]azepino[2,1-a]isoindol-8-one|Pictonamine

C21H19NO6 (381.12123140000006)


   
   

(+)-N-(methoxycarbonyl)-N-norbulbodione

(+)-N-(methoxycarbonyl)-N-norbulbodione

C20H15NO7 (381.084848)


   
   
   

13-methoxy-8-oxyberberine|13-methoxy-oxoberberine|13-Methoxyberberin|13-methoxyberberine|13-Methoxyoxoberberine|9,10,13-trimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-8-one

13-methoxy-8-oxyberberine|13-methoxy-oxoberberine|13-Methoxyberberin|13-methoxyberberine|13-Methoxyoxoberberine|9,10,13-trimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-8-one

C21H19NO6 (381.12123140000006)


   
   

(+)-(6R,8S)-1-thiomethyldiscorhabdin G*/I trifluoroacetate

(+)-(6R,8S)-1-thiomethyldiscorhabdin G*/I trifluoroacetate

C19H15N3O2S2 (381.060565)


   

celecoxib

Antibiotic CJ 14258

C17H14F3N3O2S (381.07587800000005)


M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AH - Coxibs D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors D004791 - Enzyme Inhibitors > D016861 - Cyclooxygenase Inhibitors > D052246 - Cyclooxygenase 2 Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor > C80509 - COX-2 Inhibitor COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents D002491 - Central Nervous System Agents > D000700 - Analgesics C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor D000893 - Anti-Inflammatory Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Production by Hericium ramosum. Antibiotic CJ 14258 is found in mushrooms.

   

4-Hydroxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-chromen-2-one

"NCGC00160329-01!4-Hydroxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-chromen-2-one"

C21H19NO6 (381.12123140000006)


   

PRZ_M382

PRZ_M382

C14H18Cl3N3O3 (381.0413688)


CONFIDENCE Transformation product, tentative ID (Level 3 structure); INTERNAL_ID 2012

   
   
   

N-Acetyl-9-O-lactoylneuraminic acid

N-Acetyl-9-O-lactoylneuraminic acid

C14H23NO11 (381.1271048)


   

OXOPURPUREINE

4,5,14,15,16-pentamethoxy-10-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(16),2,4,6,9(17),10,12,14-octaen-8-one

C21H19NO6 (381.12123140000006)


   

[2-(benzylcarbamoyl)-4-(2,4-difluorophenyl)phenyl] acetate

[2-(benzylcarbamoyl)-4-(2,4-difluorophenyl)phenyl] acetate

C22H17F2NO3 (381.11764360000006)


   

tert-butyl 6-(trifluoromethylsulfonyloxy)-3,4-dihydro-1H-isoquinoline-2-carboxylate

tert-butyl 6-(trifluoromethylsulfonyloxy)-3,4-dihydro-1H-isoquinoline-2-carboxylate

C15H18F3NO5S (381.08577340000005)


   

Pyrimido[2,1-f]purine-7-carboxaldehyde,1,2,3,4,8,9-hexahydro-6-hydroxy-1,3-dimethyl-2,4,8-trioxo-9-(phenylmethyl)-

Pyrimido[2,1-f]purine-7-carboxaldehyde,1,2,3,4,8,9-hexahydro-6-hydroxy-1,3-dimethyl-2,4,8-trioxo-9-(phenylmethyl)-

C18H15N5O5 (381.10731400000003)


   
   
   

Urea, N-(4-chlorophenyl)-N-cyclopropyl-N-[(1,2-dihydro-6-methyl-2-oxo-3-quinolinyl)methyl]- (9CI)

Urea, N-(4-chlorophenyl)-N-cyclopropyl-N-[(1,2-dihydro-6-methyl-2-oxo-3-quinolinyl)methyl]- (9CI)

C21H20ClN3O2 (381.12439700000004)


   

Cobalt(2+) bis(4-oxo-4-phenyl-2-buten-2-olate)

Cobalt(2+) bis(4-oxo-4-phenyl-2-buten-2-olate)

C20H18CoO4 (381.0537008)


   
   
   

N-De(4-sulfonamidophenyl)-N-(4-sulfonamidophenyl) Celecoxib

N-De(4-sulfonamidophenyl)-N-(4-sulfonamidophenyl) Celecoxib

C17H14F3N3O2S (381.07587800000005)


   
   

4-(4-chlorophenylmethyl)-6,7-dimethoxy-isoquinoline methanesulfonate (1:1)

4-(4-chlorophenylmethyl)-6,7-dimethoxy-isoquinoline methanesulfonate (1:1)

C17H16ClNO5S (381.0437676)


   

(3-bromo-4-hydroxy-3-nitropentan-2-yl) decanoate

(3-bromo-4-hydroxy-3-nitropentan-2-yl) decanoate

C15H28BrNO5 (381.11507380000006)


   

Platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane

Platinum(0)-1,3-divinyl-1,1,3,3-tetramethyldisiloxane

C8H18OPtSi2 (381.05439879999994)


   

2-Methyl-2-propanyl 3-iodo-4,4-dimethyl-1-oxa-7-azaspiro[4.4]nona ne-7-carboxylate

2-Methyl-2-propanyl 3-iodo-4,4-dimethyl-1-oxa-7-azaspiro[4.4]nona ne-7-carboxylate

C14H24INO3 (381.0800864)


   

Methanone, [4-(2-chlorophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)-

Methanone, [4-(2-chlorophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)-

C21H20ClN3O2 (381.12439700000004)


   

Tert-Butyl 3-(Iodomethyl)-2-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate

Tert-Butyl 3-(Iodomethyl)-2-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate

C14H24INO3 (381.0800864)


   

[4-(2,4-difluorophenyl)-2-(ethylcarbamoyl)phenyl] benzoate

[4-(2,4-difluorophenyl)-2-(ethylcarbamoyl)phenyl] benzoate

C22H17F2NO3 (381.11764360000006)


   

[4-(2,4-difluorophenyl)-2-(dimethylcarbamoyl)phenyl] benzoate

[4-(2,4-difluorophenyl)-2-(dimethylcarbamoyl)phenyl] benzoate

C22H17F2NO3 (381.11764360000006)


   

6-isoquinolin-5-yl-N-(1,3-thiazol-2-yl)naphthalene-1-carboxamide

6-isoquinolin-5-yl-N-(1,3-thiazol-2-yl)naphthalene-1-carboxamide

C23H15N3OS (381.09357800000004)


   

Triacetyl-ganciclovir

Triacetyl-ganciclovir

C15H19N5O7 (381.1284424)


   

Mebutizide

6-chloro-3-(3-methylpentan-2-yl)-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide

C13H20ClN3O4S2 (381.058371)


C - Cardiovascular system > C03 - Diuretics > C03A - Low-ceiling diuretics, thiazides > C03AA - Thiazides, plain C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic

   

Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate

Methyl4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-carboxylate

C17H20FN3O4S (381.11584920000007)


   

5-[(4-acetylbenzoyl)amino]-2-ethoxybenzenesulfonyl chloride

5-[(4-acetylbenzoyl)amino]-2-ethoxybenzenesulfonyl chloride

C17H16ClNO5S (381.0437676)


   
   
   

(6R,7R)-7-[[(E)-(furan-2-yl)(methoxyimino)acetyl]amino]-3-(hydroxymethyl)-8- oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-[[(E)-(furan-2-yl)(methoxyimino)acetyl]amino]-3-(hydroxymethyl)-8- oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

C15H15N3O7S (381.06306800000004)


   
   
   

ethyl 8-cyano-7-Methoxy-2-(p-tolylthioMethyl)iMidazo[1,2-a]pyridine-3-carboxylate

ethyl 8-cyano-7-Methoxy-2-(p-tolylthioMethyl)iMidazo[1,2-a]pyridine-3-carboxylate

C20H19N3O3S (381.11470640000005)


   

[1,1:3,1-Terphenyl]-4,4-dicarbonitrile, 5-(4-cyanophenyl)-

[1,1:3,1-Terphenyl]-4,4-dicarbonitrile, 5-(4-cyanophenyl)-

C27H15N3 (381.126591)


   

1-(3-(2-methoxy-5-nitrophenoxy)propyl)-4-methylpiperazine Dihydrochloride

1-(3-(2-methoxy-5-nitrophenoxy)propyl)-4-methylpiperazine Dihydrochloride

C15H25Cl2N3O4 (381.12220300000007)


   

[5-(4-chlorophenoxy)-3-[3-(trifluoromethyl)phenyl]-1,2,4-triazin-6-yl]methanol

[5-(4-chlorophenoxy)-3-[3-(trifluoromethyl)phenyl]-1,2,4-triazin-6-yl]methanol

C17H11ClF3N3O2 (381.0491852)


   

4-(4-Boc-1-piperazinyl)-5-bromo-7H-pyrrolo[2,3-d]pyrimidine

4-(4-Boc-1-piperazinyl)-5-bromo-7H-pyrrolo[2,3-d]pyrimidine

C15H20BrN5O2 (381.080028)


   

Pyridine, 4-(5-((1R)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4H-1,2,4-triazol-3-yl)-

Pyridine, 4-(5-((1R)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4H-1,2,4-triazol-3-yl)-

C19H16ClN5O2 (381.0992466)


AZD 2066 is a selective, orally active and brain-penetrant antagonist of mGluR5. AZD 2066 has antinociception effects[1].

   

1-(3-Chloro-4-Methylphenyl)-3-{2-[({5-[(Dimethylamino)methyl]-2-Furyl}methyl)thio]ethyl}urea

1-(3-Chloro-4-Methylphenyl)-3-{2-[({5-[(Dimethylamino)methyl]-2-Furyl}methyl)thio]ethyl}urea

C18H24ClN3O2S (381.12776740000004)


   

2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one

2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

C10H16N5O9P (381.0685616)


   

2-(((1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)ethanesulfonic acid

2-(((1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)ethanesulfonic acid

C12H19N3O9S (381.0841964)


   

((2R,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-nitrophenoxy)tetrahydro-2H-pyran-2-yl)methyl dihydrogen phosphate

((2R,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(4-nitrophenoxy)tetrahydro-2H-pyran-2-yl)methyl dihydrogen phosphate

C12H16NO11P (381.0460956)


   

2-(4-(2-((3,5-Dichlorophenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanoic acid

2-(4-(2-((3,5-Dichlorophenyl)amino)-2-oxoethyl)phenoxy)-2-methylpropanoic acid

C18H17Cl2NO4 (381.0534582000001)


   

1-(1-(Methylsulfonyl)piperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea

1-(1-(Methylsulfonyl)piperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea

C14H18F3N3O4S (381.09700640000005)


   

2-(2-furoylamino)-N-(3-pyridinylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide

2-(2-furoylamino)-N-(3-pyridinylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide

C20H19N3O3S (381.11470640000005)


   

N-[4-[[(2-chlorophenyl)-oxomethyl]amino]-3-methoxyphenyl]-2-pyridinecarboxamide

N-[4-[[(2-chlorophenyl)-oxomethyl]amino]-3-methoxyphenyl]-2-pyridinecarboxamide

C20H16ClN3O3 (381.08801360000007)


   

(8E)-2-amino-6-ethyl-4-(thiophen-2-yl)-8-(thiophen-2-ylmethylidene)-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile

(8E)-2-amino-6-ethyl-4-(thiophen-2-yl)-8-(thiophen-2-ylmethylidene)-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile

C20H19N3OS2 (381.09694840000003)


   

(5Z)-5-(3-Bromocyclohexa-2,5-dien-1-ylidene)-N-(pyridin-4-ylmethyl)-1,5-dihydro[1,2,4]triazolo[1,5-A]pyrimidin-7-amine

(5Z)-5-(3-Bromocyclohexa-2,5-dien-1-ylidene)-N-(pyridin-4-ylmethyl)-1,5-dihydro[1,2,4]triazolo[1,5-A]pyrimidin-7-amine

C17H14BrN6+ (381.0463244)


   

Pleconaril

Pleconaril

C18H18F3N3O3 (381.13001940000004)


J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C254 - Anti-Infective Agent > C281 - Antiviral Agent

   

cefadroxil monohydrate

cefadroxil monohydrate

C16H19N3O6S (381.0994514)


D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

   

netoglitazone

netoglitazone

C21H16FNO3S (381.08348780000006)


C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C98241 - Thiazolidinedione Antidiabetic Agent Netoglitazone is a dual agonist of PPARα and PPARγ with antihyperglycemic activity[1].

   

N-(hydroxymethyl)-N-{propyl[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl}methanimidamide

N-(hydroxymethyl)-N-{propyl[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl}methanimidamide

C14H18Cl3N3O3 (381.0413688)


   

[4,5-dihydroxy-10-oxo-3-(3-oxopentanoyl)-9H-anthracen-2-yl]acetate

[4,5-dihydroxy-10-oxo-3-(3-oxopentanoyl)-9H-anthracen-2-yl]acetate

C21H17O7- (381.0974232)


   

(4S)-2-acetyl-3,4,8,10,11,12-hexahydroxy-1,4-dihydrotetracen-1-one

(4S)-2-acetyl-3,4,8,10,11,12-hexahydroxy-1,4-dihydrotetracen-1-one

C20H13O8- (381.0610398)


   

[4,5-Dihydroxy-9,10-dioxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate

[4,5-Dihydroxy-9,10-dioxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate

C20H13O8- (381.0610398)


   

p-Nitrophenyl alpha-glucoside 6-phosphate

p-Nitrophenyl alpha-glucoside 6-phosphate

C12H16NO11P (381.0460956)


   

[(1S)-2-[2-[(2R)-2-amino-2-carboxyethyl]seleninyl-1H-imidazol-5-yl]-1-carboxyethyl]-trimethylazanium

[(1S)-2-[2-[(2R)-2-amino-2-carboxyethyl]seleninyl-1H-imidazol-5-yl]-1-carboxyethyl]-trimethylazanium

C12H21N4O5Se+ (381.0677086)


   

(5Z)-5-[[4-[(1-Pyridin-2-ylpyrrolidin-2-yl)methoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione

(5Z)-5-[[4-[(1-Pyridin-2-ylpyrrolidin-2-yl)methoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione

C20H19N3O3S (381.11470640000005)


   

N-[(3-benzamidoanilino)-sulfanylidenemethyl]-2-thiophenecarboxamide

N-[(3-benzamidoanilino)-sulfanylidenemethyl]-2-thiophenecarboxamide

C19H15N3O2S2 (381.060565)


   

1-(3,4-Dihydroxyphenyl)-2-[[5-(4-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone

1-(3,4-Dihydroxyphenyl)-2-[[5-(4-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone

C20H19N3O3S (381.11470640000005)


   

3-(2-Furanylmethyl)-8-(4-methoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile

3-(2-Furanylmethyl)-8-(4-methoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile

C20H19N3O3S (381.11470640000005)


   

1-(4-Fluorophenyl)-3-[2-methyl-5-(1-piperidinylsulfonyl)-3-furanyl]urea

1-(4-Fluorophenyl)-3-[2-methyl-5-(1-piperidinylsulfonyl)-3-furanyl]urea

C17H20FN3O4S (381.11584920000007)


   
   

5-[(4-fluorophenyl)methylsulfonylmethyl]-N-(2-oxolanylmethyl)-2-furancarboxamide

5-[(4-fluorophenyl)methylsulfonylmethyl]-N-(2-oxolanylmethyl)-2-furancarboxamide

C18H20FNO5S (381.10461620000007)


   
   

N-[(4-fluorophenyl)methyl]-2-[4-[(4-fluorophenyl)-oxomethyl]phenoxy]acetamide

N-[(4-fluorophenyl)methyl]-2-[4-[(4-fluorophenyl)-oxomethyl]phenoxy]acetamide

C22H17F2NO3 (381.11764360000006)


   

N-[[3-chloro-4-(4-morpholinyl)anilino]-sulfanylidenemethyl]-2-thiophenecarboxamide

N-[[3-chloro-4-(4-morpholinyl)anilino]-sulfanylidenemethyl]-2-thiophenecarboxamide

C16H16ClN3O2S2 (381.03724259999996)


   

1-cyclopropyl-4-[4-(trifluoromethyl)phenyl]-4H-pyridine-3,5-dicarboxylic acid dimethyl ester

1-cyclopropyl-4-[4-(trifluoromethyl)phenyl]-4H-pyridine-3,5-dicarboxylic acid dimethyl ester

C19H18F3NO4 (381.11878640000003)


   

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-dibenzofuransulfonamide

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-dibenzofuransulfonamide

C20H15NO5S (381.06709000000006)


   

4-[[(3,6-Dichloro-2-methoxyphenyl)-oxomethyl]amino]benzoic acid propyl ester

4-[[(3,6-Dichloro-2-methoxyphenyl)-oxomethyl]amino]benzoic acid propyl ester

C18H17Cl2NO4 (381.0534582000001)


   

N-[4-chloro-3-(dimethylsulfamoyl)phenyl]-2-[(phenylmethyl)amino]acetamide

N-[4-chloro-3-(dimethylsulfamoyl)phenyl]-2-[(phenylmethyl)amino]acetamide

C17H20ClN3O3S (381.09138400000006)


   

N-(3-chloro-2-methylphenyl)-2-[3-(dimethylsulfamoyl)anilino]acetamide

N-(3-chloro-2-methylphenyl)-2-[3-(dimethylsulfamoyl)anilino]acetamide

C17H20ClN3O3S (381.09138400000006)


   

2-(2-chloro-4-methylanilino)-N-[3-(dimethylsulfamoyl)phenyl]acetamide

2-(2-chloro-4-methylanilino)-N-[3-(dimethylsulfamoyl)phenyl]acetamide

C17H20ClN3O3S (381.09138400000006)


   

1-(3,4-Dihydroxyphenyl)-2-[[5-(3-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone

1-(3,4-Dihydroxyphenyl)-2-[[5-(3-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone

C20H19N3O3S (381.11470640000005)


   

2-[(2-nitro-3-pyridinyl)oxy]-N-[2-(phenylthio)phenyl]acetamide

2-[(2-nitro-3-pyridinyl)oxy]-N-[2-(phenylthio)phenyl]acetamide

C19H15N3O4S (381.07832300000007)


   

3-chloro-6-ethyl-N-(1H-indol-3-ylmethylene)-1-benzothiophene-2-carbohydrazide

3-chloro-6-ethyl-N-(1H-indol-3-ylmethylene)-1-benzothiophene-2-carbohydrazide

C20H16ClN3OS (381.07025560000005)


   

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propanamide

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propanamide

C20H19N3O5 (381.13246440000006)


   

2-methyl-N-[2-[(5-methyl-4-phenyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]benzohydrazide

2-methyl-N-[2-[(5-methyl-4-phenyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]benzohydrazide

C19H19N5O2S (381.1259394)


   

2-(7-Bromo-1-methyl-5-triazolo[4,5-c]pyridin-5-iumyl)-1-(2-naphthalenyl)ethanone

2-(7-Bromo-1-methyl-5-triazolo[4,5-c]pyridin-5-iumyl)-1-(2-naphthalenyl)ethanone

C18H14BrN4O+ (381.0350914)


   

2-[[5-(4-Fluorophenyl)-1-methyl-2-imidazolyl]thio]-1-(2-methyl-2,3-dihydroindol-1-yl)ethanone

2-[[5-(4-Fluorophenyl)-1-methyl-2-imidazolyl]thio]-1-(2-methyl-2,3-dihydroindol-1-yl)ethanone

C21H20FN3OS (381.13110420000004)


   

2-[2-[[2-[(5-Cyclopropyl-4-methyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]amino]-4-thiazolyl]acetic acid ethyl ester

2-[2-[[2-[(5-Cyclopropyl-4-methyl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]amino]-4-thiazolyl]acetic acid ethyl ester

C15H19N5O3S2 (381.09292639999995)


   

(2E)-N-{2-[(2E)-2-(1,3-benzodioxol-5-ylmethylene)hydrazino]-2-oxoethyl}-3-(2-methoxyphenyl)acrylamide

(2E)-N-{2-[(2E)-2-(1,3-benzodioxol-5-ylmethylene)hydrazino]-2-oxoethyl}-3-(2-methoxyphenyl)acrylamide

C20H19N3O5 (381.13246440000006)


   

(15R)-13-(2,5-Difluorophenyl)-10,10-dimethyl-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione

(15R)-13-(2,5-Difluorophenyl)-10,10-dimethyl-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione

C21H17F2N3O2 (381.1288766)


   

N-(4-acetylphenyl)-2-[(4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]butanamide

N-(4-acetylphenyl)-2-[(4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]butanamide

C20H19N3O3S (381.11470640000005)


   

(15R)-13-(2,4-Difluorophenyl)-10,10-dimethyl-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione

(15R)-13-(2,4-Difluorophenyl)-10,10-dimethyl-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione

C21H17F2N3O2 (381.1288766)


   
   

4-(1-Hydroxy-5,6-dimethoxy-9,10-dioxoanthracen-2-yl)-3-methylbut-3-enamide

4-(1-Hydroxy-5,6-dimethoxy-9,10-dioxoanthracen-2-yl)-3-methylbut-3-enamide

C21H19NO6 (381.12123140000006)


   

(3aR,4R,9bS)-8-bromo-4-(hydroxymethyl)-5-methyl-N-propan-2-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinoline-1-carboxamide

(3aR,4R,9bS)-8-bromo-4-(hydroxymethyl)-5-methyl-N-propan-2-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinoline-1-carboxamide

C17H24BrN3O2 (381.1051784)


   

(3aR,4S,9bS)-8-bromo-4-(hydroxymethyl)-5-methyl-N-propan-2-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinoline-1-carboxamide

(3aR,4S,9bS)-8-bromo-4-(hydroxymethyl)-5-methyl-N-propan-2-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinoline-1-carboxamide

C17H24BrN3O2 (381.1051784)


   

(3aS,4S,9bR)-8-bromo-4-(hydroxymethyl)-5-methyl-N-propan-2-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinoline-1-carboxamide

(3aS,4S,9bR)-8-bromo-4-(hydroxymethyl)-5-methyl-N-propan-2-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinoline-1-carboxamide

C17H24BrN3O2 (381.1051784)


   

(3aS,4R,9bR)-8-bromo-4-(hydroxymethyl)-5-methyl-N-propan-2-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinoline-1-carboxamide

(3aS,4R,9bR)-8-bromo-4-(hydroxymethyl)-5-methyl-N-propan-2-yl-3,3a,4,9b-tetrahydro-2H-pyrrolo[3,2-c]quinoline-1-carboxamide

C17H24BrN3O2 (381.1051784)


   

4-nitrophenyl 6-O-phosphono-beta-D-galactoside

4-nitrophenyl 6-O-phosphono-beta-D-galactoside

C12H16NO11P (381.0460956)


   

N-{5-bromo-1-[2-(morpholin-4-yl)ethyl]-2-oxo-2,3-dihydro-1H-indol-3-yl}acetamide

N-{5-bromo-1-[2-(morpholin-4-yl)ethyl]-2-oxo-2,3-dihydro-1H-indol-3-yl}acetamide

C16H20BrN3O3 (381.068795)


   

N-methyl-N-(7-nitro-2,1,3-benzoxadiazol-4-yl)-L-alpha-aspartyl-beta-alanine

N-methyl-N-(7-nitro-2,1,3-benzoxadiazol-4-yl)-L-alpha-aspartyl-beta-alanine

C14H15N5O8 (381.092059)


   

N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)tetrahydro-2H-pyran-4-carboxamide

N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)tetrahydro-2H-pyran-4-carboxamide

C17H23N3O3S2 (381.1180768)


   

4-[(5Z)-5-[(Z)-2-Methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid

4-[(5Z)-5-[(Z)-2-Methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzoic acid

C20H15NO3S2 (381.049332)


   

4-chloro-N-[(2S)-5-hydroxy-2-methyl-2,3-dihydroindol-1-yl]-3-sulfamoylbenzamide

4-chloro-N-[(2S)-5-hydroxy-2-methyl-2,3-dihydroindol-1-yl]-3-sulfamoylbenzamide

C16H16ClN3O4S (381.0550006)


   

(2E)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-(2-hydroxybenzylidene)hydrazinecarbothioamide

(2E)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-(2-hydroxybenzylidene)hydrazinecarbothioamide

C19H19N5O2S (381.1259394)


   

4-hydroxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2H-chromen-2-one

4-hydroxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2H-chromen-2-one

C21H19NO6 (381.12123140000006)


   

1,3,4,10,11,12-Hexahydroxy-6-methyltetracene-2-carboxamide

1,3,4,10,11,12-Hexahydroxy-6-methyltetracene-2-carboxamide

C20H15NO7 (381.084848)


   

N-[2-chloro-4-fluoro-5-[4-(3-fluoropropyl)-5-oxotetrazol-1-yl]phenyl]ethanesulfonamide

N-[2-chloro-4-fluoro-5-[4-(3-fluoropropyl)-5-oxotetrazol-1-yl]phenyl]ethanesulfonamide

C12H14ClF2N5O3S (381.0473908)


   

Cimicoxib

Cimicoxib

C16H13ClFN3O3S (381.03501500000004)


C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor

   

AT7519

4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide

C16H17Cl2N5O2 (381.07592420000003)


C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C2185 - Cyclin-Dependent Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent COVID info from PDB, Protein Data Bank Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

Desacetycefapirin

Desacetycefapirin

C15H15N3O5S2 (381.04531)


D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams

   

kinanthraquinone

kinanthraquinone

C21H19NO6 (381.12123140000006)


A monohydroxyanthraquinone that is anthraquinone in which the hydrogen atoms at positions 1, 2, 5 and 6 are replaced hydroxy, 3-methylbut-3-enamidyl, methoxy and methoxy groups, respectively. It is a natural product isolated from Streptomyces sp. SN-593, and shows moderate cytotoxicity against HL-60 and NRK cells.

   

ND-011992

ND-011992

C21H14F3N3O (381.108891)


ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study[1].

   

PCSK9-IN-11

PCSK9-IN-11

C16H17ClFN5O3 (381.10038940000004)


PCSK9-IN-11 (compound 5r) is a potent and orally active PCSK9 inhibitor. PCSK9-IN-11 exhibits PCSK9 transcriptional inhibitory activity in HepG2 cells, with an IC50 of 5.7 μM. PCSK9-IN-11 increases LDL receptor (LDLR) protein level. PCSK9-IN-11 can be used for atherosclerosis research[1].

   

PI3K/Akt/CREB activator 1

PI3K/Akt/CREB activator 1

C19H15F4NO3 (381.09880080000005)


PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD)[1].

   

2,7,8-trimethoxy-17,19-dioxa-11-azapentacyclo[12.7.0.0³,¹¹.0⁴,⁹.0¹⁶,²⁰]henicosa-1(21),2,4,6,8,14,16(20)-heptaen-10-one

2,7,8-trimethoxy-17,19-dioxa-11-azapentacyclo[12.7.0.0³,¹¹.0⁴,⁹.0¹⁶,²⁰]henicosa-1(21),2,4,6,8,14,16(20)-heptaen-10-one

C21H19NO6 (381.12123140000006)


   

5-(6,7-dimethoxyisoquinoline-1-carbonyl)-2h-1,3-benzodioxole-4-carboxylic acid

5-(6,7-dimethoxyisoquinoline-1-carbonyl)-2h-1,3-benzodioxole-4-carboxylic acid

C20H15NO7 (381.084848)


   

6-methyl-7,8-dihydro-2h-3',5',12'-trioxaspiro[[1,3]dioxolo[4,5-g]isoquinoline-5,11'-tricyclo[7.4.0.0²,⁶]tridecane]-1'(9'),2'(6'),7'-triene-10',13'-dione

6-methyl-7,8-dihydro-2h-3',5',12'-trioxaspiro[[1,3]dioxolo[4,5-g]isoquinoline-5,11'-tricyclo[7.4.0.0²,⁶]tridecane]-1'(9'),2'(6'),7'-triene-10',13'-dione

C20H15NO7 (381.084848)


   

6-oxocorynoline

NA

C21H19NO6 (381.12123140000006)


{"Ingredient_id": "HBIN012735","Ingredient_name": "6-oxocorynoline","Alias": "NA","Ingredient_formula": "C21H19NO6","Ingredient_Smile": "Not Available","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "16292","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}

   

4,5,15,16-tetramethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2(7),3,5,9(17),12,14-heptaene-8,11-dione

4,5,15,16-tetramethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2(7),3,5,9(17),12,14-heptaene-8,11-dione

C21H19NO6 (381.12123140000006)


   

(10z)-10-({6-[2-(dimethylamino)ethyl]-2h-1,3-benzodioxol-5-yl}methylidene)-3,5,11-trioxatricyclo[7.3.0.0²,⁶]dodeca-1(9),2(6),7-trien-12-one

(10z)-10-({6-[2-(dimethylamino)ethyl]-2h-1,3-benzodioxol-5-yl}methylidene)-3,5,11-trioxatricyclo[7.3.0.0²,⁶]dodeca-1(9),2(6),7-trien-12-one

C21H19NO6 (381.12123140000006)


   

[(4e,5e)-5-{[(2-hydroxyethyl)-c-hydroxycarbonimidoyl](phenyl)methylidene}-1,3-dioxolan-4-ylidene](phenyl)acetic acid

[(4e,5e)-5-{[(2-hydroxyethyl)-c-hydroxycarbonimidoyl](phenyl)methylidene}-1,3-dioxolan-4-ylidene](phenyl)acetic acid

C21H19NO6 (381.12123140000006)


   

18,19-dimethoxy-6,8-dioxa-14-azapentacyclo[12.8.0.0³,¹¹.0⁵,⁹.0¹⁷,²²]docosa-3,5(9),10,17,19,21-hexaene-2,15-dione

18,19-dimethoxy-6,8-dioxa-14-azapentacyclo[12.8.0.0³,¹¹.0⁵,⁹.0¹⁷,²²]docosa-3,5(9),10,17,19,21-hexaene-2,15-dione

C21H19NO6 (381.12123140000006)


   

(1r,12s,13r)-12-hydroxy-13,24-dimethyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-23-one

(1r,12s,13r)-12-hydroxy-13,24-dimethyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-23-one

C21H19NO6 (381.12123140000006)


   

4,5,15,16-tetramethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2(7),3,5,8,13,15-heptaene-11,12-dione

4,5,15,16-tetramethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2(7),3,5,8,13,15-heptaene-11,12-dione

C21H19NO6 (381.12123140000006)


   

12-hydroxy-13,24-dimethyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-23-one

12-hydroxy-13,24-dimethyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-23-one

C21H19NO6 (381.12123140000006)


   

2-({2-[(2-amino-1-hydroxypropylidene)amino]-3-carboxy-1-hydroxypropylidene}amino)-5-phosphonopent-3-enoic acid

2-({2-[(2-amino-1-hydroxypropylidene)amino]-3-carboxy-1-hydroxypropylidene}amino)-5-phosphonopent-3-enoic acid

C12H20N3O9P (381.09371200000004)


   

(2s)-1-(3-{3-carboxy-9h-pyrido[3,4-b]indol-1-yl}propanoyl)pyrrolidine-2-carboxylic acid

(2s)-1-(3-{3-carboxy-9h-pyrido[3,4-b]indol-1-yl}propanoyl)pyrrolidine-2-carboxylic acid

C20H19N3O5 (381.13246440000006)


   

(1r,12r,13s)-12-hydroxy-13,24-dimethyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-23-one

(1r,12r,13s)-12-hydroxy-13,24-dimethyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-23-one

C21H19NO6 (381.12123140000006)


   

n-[6-(4-hydroxy-2,3-dimethoxyphenyl)-2h-naphtho[2,3-d][1,3]dioxol-5-yl]-n-methylformamide

n-[6-(4-hydroxy-2,3-dimethoxyphenyl)-2h-naphtho[2,3-d][1,3]dioxol-5-yl]-n-methylformamide

C21H19NO6 (381.12123140000006)


   

n-[6-(4-hydroxy-2,5-dimethoxyphenyl)-2h-naphtho[2,3-d][1,3]dioxol-5-yl]-n-methylformamide

n-[6-(4-hydroxy-2,5-dimethoxyphenyl)-2h-naphtho[2,3-d][1,3]dioxol-5-yl]-n-methylformamide

C21H19NO6 (381.12123140000006)


   

n-[6-(2-hydroxy-3,4-dimethoxyphenyl)-2h-naphtho[2,3-d][1,3]dioxol-5-yl]-n-methylformamide

n-[6-(2-hydroxy-3,4-dimethoxyphenyl)-2h-naphtho[2,3-d][1,3]dioxol-5-yl]-n-methylformamide

C21H19NO6 (381.12123140000006)


   

1-(3-{3-carboxy-9h-pyrido[3,4-b]indol-1-yl}propanoyl)pyrrolidine-2-carboxylic acid

1-(3-{3-carboxy-9h-pyrido[3,4-b]indol-1-yl}propanoyl)pyrrolidine-2-carboxylic acid

C20H19N3O5 (381.13246440000006)


   

(5-{[(2-hydroxyethyl)-c-hydroxycarbonimidoyl](phenyl)methylidene}-1,3-dioxolan-4-ylidene)(phenyl)acetic acid

(5-{[(2-hydroxyethyl)-c-hydroxycarbonimidoyl](phenyl)methylidene}-1,3-dioxolan-4-ylidene)(phenyl)acetic acid

C21H19NO6 (381.12123140000006)


   

10-({6-[2-(dimethylamino)ethyl]-2h-1,3-benzodioxol-5-yl}methylidene)-3,5,11-trioxatricyclo[7.3.0.0²,⁶]dodeca-1(9),2(6),7-trien-12-one

10-({6-[2-(dimethylamino)ethyl]-2h-1,3-benzodioxol-5-yl}methylidene)-3,5,11-trioxatricyclo[7.3.0.0²,⁶]dodeca-1(9),2(6),7-trien-12-one

C21H19NO6 (381.12123140000006)


   

(1r)-18,19-dimethoxy-6,8-dioxa-14-azapentacyclo[12.8.0.0³,¹¹.0⁵,⁹.0¹⁷,²²]docosa-3,5(9),10,17,19,21-hexaene-2,15-dione

(1r)-18,19-dimethoxy-6,8-dioxa-14-azapentacyclo[12.8.0.0³,¹¹.0⁵,⁹.0¹⁷,²²]docosa-3,5(9),10,17,19,21-hexaene-2,15-dione

C21H19NO6 (381.12123140000006)


   

[(4e)-5-{[(2-hydroxyethyl)-c-hydroxycarbonimidoyl](phenyl)methylidene}-1,3-dioxolan-4-ylidene](phenyl)acetic acid

[(4e)-5-{[(2-hydroxyethyl)-c-hydroxycarbonimidoyl](phenyl)methylidene}-1,3-dioxolan-4-ylidene](phenyl)acetic acid

C21H19NO6 (381.12123140000006)


   

(2r,3e)-2-{[(2s)-2-{[(2s)-2-amino-1-hydroxypropylidene]amino}-3-carboxy-1-hydroxypropylidene]amino}-5-phosphonopent-3-enoic acid

(2r,3e)-2-{[(2s)-2-{[(2s)-2-amino-1-hydroxypropylidene]amino}-3-carboxy-1-hydroxypropylidene]amino}-5-phosphonopent-3-enoic acid

C12H20N3O9P (381.09371200000004)


   

4,5,14,15,16-pentamethoxy-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2(7),3,5,9(17),10,12,14-octaen-8-one

4,5,14,15,16-pentamethoxy-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2(7),3,5,9(17),10,12,14-octaen-8-one

C21H19NO6 (381.12123140000006)


   

4-(1-hydroxy-5,6-dimethoxy-9,10-dioxoanthracen-2-yl)-3-methylbut-3-enimidic acid

4-(1-hydroxy-5,6-dimethoxy-9,10-dioxoanthracen-2-yl)-3-methylbut-3-enimidic acid

C21H19NO6 (381.12123140000006)


   

16-methoxy-14-oxo-5,7-dioxa-13-azapentacyclo[11.8.0.0²,¹⁰.0⁴,⁸.0¹⁵,²⁰]henicosa-2,4(8),9,15(20),16,18-hexaen-17-yl acetate

16-methoxy-14-oxo-5,7-dioxa-13-azapentacyclo[11.8.0.0²,¹⁰.0⁴,⁸.0¹⁵,²⁰]henicosa-2,4(8),9,15(20),16,18-hexaen-17-yl acetate

C21H19NO6 (381.12123140000006)


   

(15s,17s)-9,17-dihydroxy-5,11,15,16,16-pentamethyl-6,14-dioxa-4-azapentacyclo[10.6.1.0³,⁷.0⁸,¹⁹.0¹³,¹⁷]nonadeca-1(19),3(7),4,8,10,12-hexaene-2,18-dione

(15s,17s)-9,17-dihydroxy-5,11,15,16,16-pentamethyl-6,14-dioxa-4-azapentacyclo[10.6.1.0³,⁷.0⁸,¹⁹.0¹³,¹⁷]nonadeca-1(19),3(7),4,8,10,12-hexaene-2,18-dione

C21H19NO6 (381.12123140000006)


   

n-[6-(2-hydroxy-4,5-dimethoxyphenyl)-2h-naphtho[2,3-d][1,3]dioxol-5-yl]-n-methylformamide

n-[6-(2-hydroxy-4,5-dimethoxyphenyl)-2h-naphtho[2,3-d][1,3]dioxol-5-yl]-n-methylformamide

C21H19NO6 (381.12123140000006)


   

9,17-dihydroxy-5,11,15,16,16-pentamethyl-6,14-dioxa-4-azapentacyclo[10.6.1.0³,⁷.0⁸,¹⁹.0¹³,¹⁷]nonadeca-1(19),3(7),4,8,10,12-hexaene-2,18-dione

9,17-dihydroxy-5,11,15,16,16-pentamethyl-6,14-dioxa-4-azapentacyclo[10.6.1.0³,⁷.0⁸,¹⁹.0¹³,¹⁷]nonadeca-1(19),3(7),4,8,10,12-hexaene-2,18-dione

C21H19NO6 (381.12123140000006)


   

(10e)-10-({6-[2-(dimethylamino)ethyl]-2h-1,3-benzodioxol-5-yl}methylidene)-3,5,11-trioxatricyclo[7.3.0.0²,⁶]dodeca-1(9),2(6),7-trien-12-one

(10e)-10-({6-[2-(dimethylamino)ethyl]-2h-1,3-benzodioxol-5-yl}methylidene)-3,5,11-trioxatricyclo[7.3.0.0²,⁶]dodeca-1(9),2(6),7-trien-12-one

C21H19NO6 (381.12123140000006)