Lavendustin A (BioDeep_00000180406)
human metabolite blood metabolite natural product
代谢物信息卡片
5-{[(2,5-dihydroxyphenyl)methyl][(2-hydroxyphenyl)methyl]amino}-2-hydroxybenzoic acid
化学式: C21H19NO6 (381.12123140000006)
中文名称: 薰草菌素
谱图信息:
最多检出来源 Homo sapiens(blood) 99.71%
分子结构信息
SMILES: C1=CC=C(C(=C1)CN(CC2=C(C=CC(=C2)O)O)C3=CC(=C(C=C3)O)C(=O)O)O
InChI: InChI=1S/C21H19NO6/c23-16-6-8-19(25)14(9-16)12-22(11-13-3-1-2-4-18(13)24)15-5-7-20(26)17(10-15)21(27)28/h1-10,23-26H,11-12H2,(H,27,28)
描述信息
C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor
D004791 - Enzyme Inhibitors
同义名列表
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:92413
- PubChem: 3894
- HMDB: HMDB0253995
- ChEMBL: CHEMBL103552
- KNApSAcK: C00028455
- chemspider: 3757
- CAS: 125697-92-9
- LOTUS: LTS0107462
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 2 - Bacteria: LTS0107462
- 9606 - Homo sapiens: -
- 1883 - Streptomyces: 10.1021/NP50066A009
- 1883 - Streptomyces: LTS0107462
- 2062 - Streptomycetaceae: LTS0107462
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hong-Bin Liu, Xiaoxu Li, Jun Cai, Ling-Li Jiang, Xin Zhang, Dousheng Wu, Lifeng Wang, Aiguo Yang, Cun Guo, Jia Chen, Wenxuan Pu, Feng Yu. A screening of inhibitors targeting the receptor kinase FERONIA reveals small molecules that enhance plant root immunity.
Plant biotechnology journal.
2023 01; 21(1):63-77. doi:
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Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Valentina De Chiara, Francesco Angelucci, Silvia Rossi, Alessandra Musella, Francesca Cavasinni, Cristina Cantarella, Giorgia Mataluni, Lucia Sacchetti, Francesco Napolitano, Maura Castelli, Carlo Caltagirone, Giorgio Bernardi, Mauro Maccarrone, Alessandro Usiello, Diego Centonze. Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2010 Jun; 30(24):8127-37. doi:
10.1523/jneurosci.1683-10.2010. [PMID: 20554863] - D Spicarova, J Palecek. Modulation of AMPA excitatory postsynaptic currents in the spinal cord dorsal horn neurons by insulin.
Neuroscience.
2010 Mar; 166(1):305-11. doi:
10.1016/j.neuroscience.2009.12.007. [PMID: 20005924] - Yoshiko Kawai, Yuka Kohda, Takaaki Kodawara, Munekazu Gemba. Protective effect of a protein kinase inhibitor on cellular injury induced by cephaloridine in the porcine kidney cell line LLC-PK(1).
The Journal of toxicological sciences.
2005 Aug; 30(3):157-63. doi:
10.2131/jts.30.157. [PMID: 16141650] - Ximena Ortega, Juan Carlos Velásquez, Luz M Pérez. IP3 production in the hypersensitive response of lemon seedlings against Alternaria alternata involves active protein tyrosine kinases but not a G-protein.
Biological research.
2005; 38(1):89-99. doi:
10.4067/s0716-97602005000100011. [PMID: 15977414] - Takeshi Yamaguchi, Shigeru Tanabe, Eiichi Minami, Naoto Shibuya. Activation of phospholipase D induced by hydrogen peroxide in suspension-cultured rice cells.
Plant & cell physiology.
2004 Sep; 45(9):1261-70. doi:
10.1093/pcp/pch150. [PMID: 15509849] - C L Chik, B Li, E Karpinski, A K Ho. Ceramide inhibits L-type calcium channel currents in GH3 cells.
Molecular and cellular endocrinology.
2004 Apr; 218(1-2):175-83. doi:
10.1016/j.mce.2003.10.048. [PMID: 15130522] - V L Colston, T J Wheeler. Stimulation of cardiac glucose transport by inhibitors of oxidative phosphorylation.
Life sciences.
2001 Oct; 69(20):2383-98. doi:
10.1016/s0024-3205(01)01325-x. [PMID: 11681625] - S Doolen, N R Zahniser. Protein tyrosine kinase inhibitors alter human dopamine transporter activity in Xenopus oocytes.
The Journal of pharmacology and experimental therapeutics.
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2000 Nov; 36(5 Suppl 1):S248-51. doi:
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Brain research. Molecular brain research.
1999 Apr; 67(1):177-83. doi:
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The Journal of membrane biology.
1998 Feb; 161(3):235-45. doi:
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Kidney international.
1997 Jun; 51(6):1747-53. doi:
10.1038/ki.1997.240. [PMID: 9186862] - N Sekine, S Ullrich, R Regazzi, W F Pralong, C B Wollheim. Postreceptor signalling of growth hormone and prolactin and their effects in the differentiated insulin-secreting cell line, INS-1.
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The Journal of endocrinology.
1995 Aug; 146(2):261-70. doi:
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The Journal of biological chemistry.
1995 Mar; 270(13):7765-72. doi:
10.1074/jbc.270.13.7765. [PMID: 7535777] - A de S Otero, N M Sweitzer. Benzoquinoid tyrosine kinase inhibitors are potent blockers of cardiac muscarinic receptor function.
Molecular pharmacology.
1993 Sep; 44(3):595-604. doi:
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1993 Mar; 132(3):1387-95. doi:
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Molecular and cellular endocrinology.
1993 Mar; 92(1):127-34. doi:
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