Exact Mass: 354.1863
Exact Mass Matches: 354.1863
Found 500 metabolites which its exact mass value is equals to given mass value 354.1863,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Vincamine
Vincamine is a vinca alkaloid, an alkaloid ester, an organic heteropentacyclic compound, a methyl ester and a hemiaminal. It has a role as an antihypertensive agent, a vasodilator agent and a metabolite. It is functionally related to an eburnamenine. Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of *Vinca minor* with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow. Vincamine is a natural product found in Vinca difformis, Vinca major, and other organisms with data available. A major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders. Vincamine. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=1617-90-9 (retrieved 2024-07-01) (CAS RN: 1617-90-9). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). Vincamine?is a monoterpenoid indole alkaloid extracted from the?Madagascar periwinkle. Vincamine?is a peripheral?vasodilator?and exerts a selective vasoregulator action on the brain microcapilar circulation[1]. Vincamine?is a?GPR40?agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS).?Vincamine?improves glucose homeostasis?in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research[2]. Vincamine?is a monoterpenoid indole alkaloid extracted from the?Madagascar periwinkle. Vincamine?is a peripheral?vasodilator?and exerts a selective vasoregulator action on the brain microcapilar circulation[1]. Vincamine?is a?GPR40?agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS).?Vincamine?improves glucose homeostasis?in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research[2].
Yohimbine
Yohimbine is an indole alkaloid with alpha2-adrenoceptor antagonist activity. It is produced by Corynanthe johimbe and Rauwolfia serpentina. It has a role as an alpha-adrenergic antagonist, a serotonergic antagonist and a dopamine receptor D2 antagonist. It is functionally related to a yohimbic acid. A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac. Yohimbine is an indole alkaloid derived from the bark of the Central African yohimbe tree (Pausinystalia yohimbe) that is widely used as therapy for erectile dysfunction. Yohimbine use has been associated with occasional severe adverse events, but has not been linked to serum enzyme elevations or clinically apparent acute liver injury. Yohimbine is a natural product found in Rauvolfia yunnanensis, Tabernaemontana corymbosa, and other organisms with data available. A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION. See also: Yohimbine Hydrochloride (active moiety of) ... View More ... Yohimbine is only found in individuals that have used or taken this drug. It is a plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac. [PubChem]Yohimbine is a pre-synaptic alpha 2-adrenergic blocking agent. The exact mechanism for its use in impotence has not been fully elucidated. However, yohimbine may exert its beneficial effect on erectile ability through blockade of central alpha 2-adrenergic receptors producing an increase in sympathetic drive secondary to an increase in norepinephrine release and in firing rate of cells in the brain noradrenergic nuclei. Yohimbine-mediated norepinephrine release at the level of the corporeal tissues may also be involved. In addition, beneficial effects may involve other neurotransmitters such as dopamine and serotonin and cholinergic receptors. G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals > G04BE - Drugs used in erectile dysfunction An indole alkaloid with alpha2-adrenoceptor antagonist activity. It is produced by Corynanthe johimbe and Rauwolfia serpentina. C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D009184 - Mydriatics D000089162 - Genitourinary Agents > D064804 - Urological Agents D001697 - Biomedical and Dental Materials > D003764 - Dental Materials Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. IC50 value: 0.6 uM [1] Target: alpha 2-adrenergic receptor in vitro: Yohimbine inhibits alpha2-receptor antagonist with Ki of 1.05 nM, 1.19 nM, and 1.19 nM for α2A, α2B, α2C, respectively. Yohimbine also inhibits 5-HT1B with Ki of 19.9 nM. Yohimbine acts to block the lowering of cAMP by alpha-2 adrenoceptor agonists. yohimbine actually causes a pronounced lowering of tyrosinase activity. [3] in vivo: Yohimbine is an antagonist at alpha2-noradrenaline receptors with putative panicogenic effects in human subjects, was administered to Swiss-Webster mice at doses of 0.5, 1.0, and 2.0 mg/kg. Yohimbine potentiates active defensive responses to threatening stimuli in Swiss-Webster mice.[2] Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. IC50 value: 0.6 uM [1] Target: alpha 2-adrenergic receptor in vitro: Yohimbine inhibits alpha2-receptor antagonist with Ki of 1.05 nM, 1.19 nM, and 1.19 nM for α2A, α2B, α2C, respectively. Yohimbine also inhibits 5-HT1B with Ki of 19.9 nM. Yohimbine acts to block the lowering of cAMP by alpha-2 adrenoceptor agonists. yohimbine actually causes a pronounced lowering of tyrosinase activity. [3] in vivo: Yohimbine is an antagonist at alpha2-noradrenaline receptors with putative panicogenic effects in human subjects, was administered to Swiss-Webster mice at doses of 0.5, 1.0, and 2.0 mg/kg. Yohimbine potentiates active defensive responses to threatening stimuli in Swiss-Webster mice.[2]
Tephrowatsin A
A hydroxyflavan that is (2S)-flavan substituted by hydroxy group at position 4, methoxy groups at positions 5 and 7 and a prenyl group at position 8 respectively.
17-O-acetylnorajmaline
An indole alkaloid obtained by formal acetylation of the 17-hydroxy group of norajmaline.
3,6-Dimethoxyestra-1,3,5(10),6,8-pentaene-17beta-carboxylic acid methyl ester
N-demethylvindolidine
Corynanthin
Methyl 17-hydroxy-20xi-yohimban-16-carboxylate is a yohimban alkaloid, a methyl ester and an organic heteropentacyclic compound. Methyl 17-hydroxy-20xi-yohimban-16-carboxylate is a natural product found in Aspidosperma oblongum, Aspidosperma ramiflorum, and other organisms with data available. D001697 - Biomedical and Dental Materials > D003764 - Dental Materials
Acetylsalvipisone
Acetylsalvipisone is found in alcoholic beverages. Acetylsalvipisone is a constituent of Salvia sclarea (clary sage)
1-dodecanoyl-glycero-3-phosphate
1-dodecanoyl-glycero-3-phosphate is also known as LPA(12:0/0:0) or (2R)-2-Hydroxy-3-(phosphonooxy)propyl laurate. 1-dodecanoyl-glycero-3-phosphate is considered to be practically insoluble (in water) and acidic. 1-dodecanoyl-glycero-3-phosphate is a glycerophosphate lipid molecule
LysoPA(i-12:0/0:0)
LysoPA(i-12:0/0:0) is a lysophosphatidic acid. It is a glycerophospholipid in which a phosphate moiety occupies a glycerol substitution site. Lysophosphatidic acids can have different combinations of fatty acids of varying lengths and saturation attached at the C-1 (sn-1) or C-2 (sn-2) position. Fatty acids containing 16 and 18 carbons are the most common. LysoPA(i-12:0/0:0), in particular, consists of one chain of isododecanoic acid at the C-1 position. Lysophosphatidic acid is the simplest possible glycerophospholipid. It is the biosynthetic precursor of phosphatidic acid. Although it is present at very low levels only in animal tissues, it is extremely important biologically, influencing many biochemical processes.
3-(4-(2-Dimethylamino-1-methylethoxy)phenyl)-1H-pyrazolo(3,4-b)pyridine-1-acetic acid
Corynanthine
Ethyl (2S,3S)-3-[[(2S)-1-[[(2S)-1-hydroxypent-4-yn-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylate
Isovincamine
Bronica
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D011448 - Prostaglandin Antagonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents R - Respiratory system > R03 - Drugs for obstructive airway diseases D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents Seratrodast (AA 2414), an orally active antiasthmatic agent, is a thromboxane A2 receptor (TP) antagonist and ferroptosis inhibitor. Seratrodast reduces lipid ROS production, modulates the systemic xc-/GSH/GPX4 axis, and inhibits JNK phosphorylation and p53 expression. Seratrodast exhibits anti-asthmatic and anti-epileptic activity[1][2][3].
7-(2,5-Dihydroxy-3,4,6-trimethylphenyl)-7-phenylhept-6-enoic acid
17-O-acetylnorajmaline
17-o-acetylnorajmaline is a member of the class of compounds known as ajmaline-sarpagine alkaloids. Ajmaline-sarpagine alkaloids are organic compounds containing either of the ajmalan, sarpagan skeleton, or derivative thereof. The Sarpagine (Akuammidine) group, based on the sarpagan nucleus, arises from bond formation between C-16 and C-5 of the corynantheine precursor. Ajmaline alkaloids are based on a 17,19-secoyohimban skeleton (oxayohimban) which is invariably present as an ether. 17-o-acetylnorajmaline is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 17-o-acetylnorajmaline can be found in a number of food items such as black chokeberry, sapodilla, common pea, and cardamom, which makes 17-o-acetylnorajmaline a potential biomarker for the consumption of these food products.
(1R,2S,4S,7Z,8R,9S)-7-ethylidene-1-methoxy-5-methylspiro[11-oxa-5-azatricyclo[6.3.1.0^{4,9]dodecane-2,3-indole]-2-one
Dregamine
A monoterpenoid indole alkaloid with formula C21H26N2O3, isolated from several species of Tabernaemontana.
11-Dimethyl-3-[(acetyloxy)methyl]-7 2,6,11-dodecatriene-1,5,10-triol 1-acetate
Sitsirikine
methyl (2R)-2-[(2S,3R,12bS)-3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-hydroxypropanoate is a natural product found in Alstonia angustifolia, Rauvolfia caffra, and Strychnos pungens with data available.
10-Hydroxycoronaridine
An organic heteropentacyclic compound that is coronaridine in which the hydrogen of the indole moiety that is para- to the indole nitrogen has been replaced by a hydroxy group.
(2E)-3-(4-Acetoxy-2,3-dihydroxy-2,5,5,8a-tetramethyldecahydro-1-naphthalenyl)acrylic acid
(+/-)-N-formyltortuosamine|N-Formyl-(??)-(??)-Tortuosamine|N-Formyltortuosamin|N-formyltortuosamine|N-{2-[6-(3,4-dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-ethyl}-N-methyl-formamide
16-hydroxymethyl-4,5-seco-condyfol-14(19)-ene-16-carboxylic acid methyl ester|Precondylocarpin
Corynanthine
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D009184 - Mydriatics D000089162 - Genitourinary Agents > D064804 - Urological Agents Annotation level-1 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.574 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.571 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.566 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.567
Ibogamine-18-carboxylicacid, 13-hydroxy-, methyl ester (9CI)
tabernaemontanine
A monoterpenoid indole alkaloid with formula C21H26N2O3, isolated from several species of Tabernaemontana.
17-hydroxy-19,20-dihydro-sarpagane-16-carboxylic acid methyl ester|19, 20-Dihydropolyneuridine|Dihydroakuammidin
(ent-5alpha,15()-16-Chloro-3,15-dihydroxy-3-erythroxylen-2-one
(17alpha)-17-hydroxykopsinine|(2alpha,3beta,4alpha,5alpha,12R,19alpha)-4-hydroxy-2,21-cycloaspidospermidine-3-carboxylic acid|17alpha-hydroxykopsinine|kopsiloscine G
3,5-Ethano-3H-pyrrolo[2,3-d]carbazole-6-carboxylic acid, 4-ethyl-1,2,3a,4,5,7-hexahydro-11-methoxy-, methyl ester, stereoisomer
1-methyl-3-(2-hydroxypropan-2-yl)-2-(5-methoxy-9H-beta-carbolin-1-yl)cyclopentanol
11,12-dimethoxy-14,15-dihydro-eburnamenin-14-one|Dimethoxy-eburnamonin|Dimethoxyeburnamonine
3,10-dihydroxy-5,8-diacetoxy-1(2),11(12)-dehydrofarnesol
(+-)-Vincamin|14-hydroxy-14,15-dihydro-eburnamenine-14-carboxylic acid methyl ester|Vinkamin
flabelliformine|methyl (3E,4S)-3-ethylidene-4-{1-[3-(methoxymethyl)-1H-indol-2-yl]ethenyl}piperidine-1-carboxylate
4-hydroxy-2-(hydroxymethyl)-5-[(3Z)-1,5,6-trihydroxy-1,5,6,7-tetramethyl-3,7-octadienyl]-2-cyclohexen-1-one|antheminone B
ent-5alpha,16-chloro-2-oxodolabr-3-ene-3,15xi-diol
20-Epiervatamin|4-ethyl-2-methyl-6-oxo-2,3,4,4a,5,6,7,12-octahydro-1H-pyrido[3,4:4,5]cyclohepta[1,2-b]indole-12a-carboxylic acid methyl ester
(19S)-1-acetyl-17,19-epoxy-curan-3-ol|Acetylisostrychnosplendine|N(a)-Acetyl-isostrychnosplendin|N-acetyl-isostrychnosplendine
12-hydroxy-21,22-dihydro-12,24-seco-strychnidin-10-one|Protostrychnin|Protostrychnine
2,3-Dimethoxy-7-methyl-9,10-methylenedioxy-5,6,13,13a-tetrahydro-8H-dibenzo[a,g]quinolizine-7-ium
Rauwolscine
Rauwolscine is a methyl 17-hydroxy-20xi-yohimban-16-carboxylate. Rauwolscine is a natural product found in Alstonia constricta, Corynanthe johimbe, and other organisms with data available. A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION. D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D009184 - Mydriatics D000089162 - Genitourinary Agents > D064804 - Urological Agents relative retention time with respect to 9-anthracene Carboxylic Acid is 0.457 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.455 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.451 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.448 Rauwolscine is a selective α2-adrenoceptor antagonist that inhibits tumor growth and induces apoptosis[1].
Alloyohimbin
Allo-yohimbine is a methyl 17-hydroxy-20xi-yohimban-16-carboxylate. allo-Yohimbine is a natural product found in Corynanthe johimbe, Alstonia yunnanensis, and other organisms with data available.
Humantenine
Annotation level-1 Humantenine is a natural product found in Gelsemium elegans and Gelsemium rankinii with data available.
Yohimbine
G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals > G04BE - Drugs used in erectile dysfunction C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D009184 - Mydriatics D000089162 - Genitourinary Agents > D064804 - Urological Agents CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2282 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.556 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.553 Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. IC50 value: 0.6 uM [1] Target: alpha 2-adrenergic receptor in vitro: Yohimbine inhibits alpha2-receptor antagonist with Ki of 1.05 nM, 1.19 nM, and 1.19 nM for α2A, α2B, α2C, respectively. Yohimbine also inhibits 5-HT1B with Ki of 19.9 nM. Yohimbine acts to block the lowering of cAMP by alpha-2 adrenoceptor agonists. yohimbine actually causes a pronounced lowering of tyrosinase activity. [3] in vivo: Yohimbine is an antagonist at alpha2-noradrenaline receptors with putative panicogenic effects in human subjects, was administered to Swiss-Webster mice at doses of 0.5, 1.0, and 2.0 mg/kg. Yohimbine potentiates active defensive responses to threatening stimuli in Swiss-Webster mice.[2] Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. IC50 value: 0.6 uM [1] Target: alpha 2-adrenergic receptor in vitro: Yohimbine inhibits alpha2-receptor antagonist with Ki of 1.05 nM, 1.19 nM, and 1.19 nM for α2A, α2B, α2C, respectively. Yohimbine also inhibits 5-HT1B with Ki of 19.9 nM. Yohimbine acts to block the lowering of cAMP by alpha-2 adrenoceptor agonists. yohimbine actually causes a pronounced lowering of tyrosinase activity. [3] in vivo: Yohimbine is an antagonist at alpha2-noradrenaline receptors with putative panicogenic effects in human subjects, was administered to Swiss-Webster mice at doses of 0.5, 1.0, and 2.0 mg/kg. Yohimbine potentiates active defensive responses to threatening stimuli in Swiss-Webster mice.[2]
methyl 18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
methyl 18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
C19H30O6_(2E)-3-(4-Acetoxy-2,3-dihydroxy-2,5,5,8a-tetramethyldecahydro-1-naphthalenyl)acrylic acid
C21H26N2O3_Methyl (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylate
(E)-3-(4-acetyloxy-2,3-dihydroxy-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl)prop-2-enoic acid
Alloyohimbine
Origin: Plant; SubCategory_DNP: Monoterpenoid indole alkaloids, Yohimbinoid alkaloids, Indole alkaloids
Vincamin
C - Cardiovascular system > C04 - Peripheral vasodilators > C04A - Peripheral vasodilators D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents D000970 - Antineoplastic Agents > D014748 - Vinca Alkaloids CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2327 Vincamine?is a monoterpenoid indole alkaloid extracted from the?Madagascar periwinkle. Vincamine?is a peripheral?vasodilator?and exerts a selective vasoregulator action on the brain microcapilar circulation[1]. Vincamine?is a?GPR40?agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS).?Vincamine?improves glucose homeostasis?in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research[2]. Vincamine?is a monoterpenoid indole alkaloid extracted from the?Madagascar periwinkle. Vincamine?is a peripheral?vasodilator?and exerts a selective vasoregulator action on the brain microcapilar circulation[1]. Vincamine?is a?GPR40?agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS).?Vincamine?improves glucose homeostasis?in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research[2].
2,2,4-Trimethylpentane-1,3-diyl dibenzoate
CONFIDENCE standard compound; INTERNAL_ID 1387; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10463; ORIGINAL_PRECURSOR_SCAN_NO 10461 CONFIDENCE standard compound; INTERNAL_ID 1387; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10565; ORIGINAL_PRECURSOR_SCAN_NO 10560 CONFIDENCE standard compound; INTERNAL_ID 1387; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10586; ORIGINAL_PRECURSOR_SCAN_NO 10581
Ala Ala Pro Pro
Ala Pro Ala Pro
Ala Pro Pro Ala
Pro Ala Ala Pro
Pro Ala Pro Ala
Pro Pro Ala Ala
5-hydroperoxy-7-[3,5-epidioxy-2-(2-octenyl)-cyclopentyl]-6-heptenoic acid
Idebenone Metabolite (Benzenedecanoic acid, 2,5-dihydroxy-3,4-dimethoxy-6-methyl-)
Acetylsalvipisone
1,5-DIPHENYL-4-ETHYL-3-(4-METHOXYPHENYL)-1H-PYRAZOLE
6-[3-[[tert-butyl(dimethyl)silyl]oxymethyl]pyrrolidin-1-yl]-2-fluoropyridine-3-carboxylic acid
(2S,3S)-[2-(3-HYDROXYPYRROLIDIN-1-YL)-1-PHENYLETHYL]METHYLCARBAMICACIDBENZYLESTER
2-(4-Tert-Butylphenyl)-5-(4-Biphenyl)-1,3,4-Oxadiazole
N-(hydroxymethyl)prop-2-enamide,2-methylidenebutanoic acid,methyl 2-methylprop-2-enoate,prop-2-enenitrile
1,2:5,6-DI-O-CYCLOHEXYLIDENE-3-O-METHYL-ALPHA-D-GLUCOFURANOSE
Ethyl 2-(hydroxy(4-Methoxy-3-(3-Methoxypropoxy)phenyl)Methyl)-3-Methylbutanoate
BENZYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-3-YLCARBAMATE
N-(6-METHOXY-PYRIDIN-3-YL)-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZAMIDE
N-Benzyl-2-nitro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
1,3-DIPHENYL-4-ETHYL-5-(4-METHOXYPHENYL)-1H-PYRAZOLE
3,7-Dioxa-4,6-disilanonane, 4,4,6,6-tetraethoxy-5-methyl-
Iclaprim
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01EA - Trimethoprim and derivatives C471 - Enzyme Inhibitor > C2153 - Dihydrofolate Reductase Inhibitor D004791 - Enzyme Inhibitors > D005493 - Folic Acid Antagonists C254 - Anti-Infective Agent > C258 - Antibiotic
4,4-bis-(2,3-Epoxypropoxy)-3,3,5,5-tetramethylbiphenyl
1-hydroxy-6,6,9-trimethyl-3-pentylbenzo[c]chromene-2-carboxylic acid
Benzyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate
TERT-BUTYL 4-AMINOSPIRO[CHROMAN-2,4-PIPERIDINE]-1-CARBOXYLATE HYDROCHLORIDE
BENZYL (5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-3-YL)CARBAMATE
5-(9-Isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2152 - Phosphatidylinositide 3-Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor VS-5584 is a pan-PI3K/mTOR kinase inhibitor with IC50s of 16 nM, 68 nM, 42 nM, 25 nM, and 37 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively. VS-5584 simultaneously blocks mTORC2 as well as mTORC1. VS-5584 is a pan-PI3K/mTOR kinase inhibitor with IC50s of 16 nM, 68 nM, 42 nM, 25 nM, and 37 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively. VS-5584 simultaneously blocks mTORC2 as well as mTORC1.
5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine
vinca
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents D000970 - Antineoplastic Agents > D014748 - Vinca Alkaloids
4-(2-((2-Hydroxy-3-(1H-indol-4-yloxy)propyl)amino)-2-methylpropyl)phenol
1-[2-[[3-(2-Cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-3-phenylurea
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists
3-(3,5-Dimethyl-1-pyrazolyl)-6-[4-(4-fluorophenyl)-1-piperazinyl]-1,2,4,5-tetrazine
4-(9H-fluoren-9-yl)-N-(4-pyridinylmethylene)-1-piperazinamine
7-Amino-2-Tert-Butyl-4-{[2-(1h-Imidazol-4-Yl)ethyl]amino}pyrido[2,3-D]pyrimidine-6-Carboxamide
Seratrodast
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D011448 - Prostaglandin Antagonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents R - Respiratory system > R03 - Drugs for obstructive airway diseases D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents Seratrodast (AA 2414), an orally active antiasthmatic agent, is a thromboxane A2 receptor (TP) antagonist and ferroptosis inhibitor. Seratrodast reduces lipid ROS production, modulates the systemic xc-/GSH/GPX4 axis, and inhibits JNK phosphorylation and p53 expression. Seratrodast exhibits anti-asthmatic and anti-epileptic activity[1][2][3].
Corynine
G - Genito urinary system and sex hormones > G04 - Urologicals > G04B - Urologicals > G04BE - Drugs used in erectile dysfunction C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D009184 - Mydriatics D000089162 - Genitourinary Agents > D064804 - Urological Agents Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. IC50 value: 0.6 uM [1] Target: alpha 2-adrenergic receptor in vitro: Yohimbine inhibits alpha2-receptor antagonist with Ki of 1.05 nM, 1.19 nM, and 1.19 nM for α2A, α2B, α2C, respectively. Yohimbine also inhibits 5-HT1B with Ki of 19.9 nM. Yohimbine acts to block the lowering of cAMP by alpha-2 adrenoceptor agonists. yohimbine actually causes a pronounced lowering of tyrosinase activity. [3] in vivo: Yohimbine is an antagonist at alpha2-noradrenaline receptors with putative panicogenic effects in human subjects, was administered to Swiss-Webster mice at doses of 0.5, 1.0, and 2.0 mg/kg. Yohimbine potentiates active defensive responses to threatening stimuli in Swiss-Webster mice.[2] Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. IC50 value: 0.6 uM [1] Target: alpha 2-adrenergic receptor in vitro: Yohimbine inhibits alpha2-receptor antagonist with Ki of 1.05 nM, 1.19 nM, and 1.19 nM for α2A, α2B, α2C, respectively. Yohimbine also inhibits 5-HT1B with Ki of 19.9 nM. Yohimbine acts to block the lowering of cAMP by alpha-2 adrenoceptor agonists. yohimbine actually causes a pronounced lowering of tyrosinase activity. [3] in vivo: Yohimbine is an antagonist at alpha2-noradrenaline receptors with putative panicogenic effects in human subjects, was administered to Swiss-Webster mice at doses of 0.5, 1.0, and 2.0 mg/kg. Yohimbine potentiates active defensive responses to threatening stimuli in Swiss-Webster mice.[2]
Stemmadenin
A monoterpenoid indole alkaloid with formula C21H26N2O3, isolated from several plant species including Rhazya stricta, Tabernaemontana dichotoma and Aspidosperma pyricollum.
methyl (2R)-2-[(2R,3Z,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-hydroxypropanoate
(1E,2E,4E)-1-[5-[(4-hydroxyphenyl)methyl]-2,4-dioxopyrrolidin-3-ylidene]-4,6-dimethylocta-2,4-dien-1-olate
7-(2,5-Dihydroxy-3,4,6-trimethylphenyl)-7-phenylhept-6-enoic acid
Ethyl (2S,3S)-3-[[(2S)-1-[[(2S)-1-hydroxypent-4-yn-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylate
[3-carboxy-2-[(2E,5E,7E)-10-carboxydeca-2,5,7-trienoyl]oxypropyl]-trimethylazanium
[3-carboxy-2-[(4E,6E,8E)-10-carboxydeca-4,6,8-trienoyl]oxypropyl]-trimethylazanium
[3-carboxy-2-[(5E,7E,9E)-10-carboxydeca-5,7,9-trienoyl]oxypropyl]-trimethylazanium
[3-carboxy-2-[(3E,6E,9E)-10-carboxydeca-3,6,9-trienoyl]oxypropyl]-trimethylazanium
7-Benzyl-1,3-dimethyl-8-piperazin-1-yl-3,7-dihydro-purine-2,6-dione
Ala-Ala-Pro-Pro
A tetrapeptide composed of two L-alanine units joined to two L-proline units by peptide linkages.
(1S,15R,18S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid methyl ester
(1S,15R,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid methyl ester
(-)-Minovincinine
A monoterpenoid indole alkaloid that is (-)-vincadifformine which carries a hydroxy group at position 19R. A natural product found in several plant species including Catharanthus roseus and Vinca minor.
N-hydroxy-N-[(E)-(4-pyridin-2-ylphenyl)methylideneamino]heptanediamide
N-hydroxy-N-[(E)-(4-pyridin-4-ylphenyl)methylideneamino]heptanediamide
N-hydroxy-N-[(E)-(4-pyridin-3-ylphenyl)methylideneamino]heptanediamide
1-(4-methoxyphenyl)-N-[2-(4-morpholinyl)ethyl]-4-pyrazolo[3,4-d]pyrimidinamine
N-[2-[4-(dimethylamino)phenyl]-4-oxo-1,2-dihydroquinazolin-3-yl]carbamic acid ethyl ester
1-(2,4-Diphenyl-2,3-dihydro-1,5-benzodiazepin-1-yl)propan-1-one
1-[(2R,3R)-1-[(2-fluorophenyl)methyl]-2-(hydroxymethyl)-3-phenyl-1,6-diazaspiro[3.3]heptan-6-yl]ethanone
1-[(2S,3R)-1-[(2-fluorophenyl)methyl]-2-(hydroxymethyl)-3-phenyl-1,6-diazaspiro[3.3]heptan-6-yl]ethanone
1-[(2S,3S)-1-[(2-fluorophenyl)methyl]-2-(hydroxymethyl)-3-phenyl-1,6-diazaspiro[3.3]heptan-6-yl]ethanone
(1R,15R,18S,19R,20R)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid methyl ester
[(1R,9R,10S,12R,13S,14R,16S,18R)-13-ethyl-14-hydroxy-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-trien-18-yl] acetate
Propyl 2,7,7-trimethyl-5-oxo-4-pyridin-3-yl-3,4,6,8-tetrahydroquinoline-3-carboxylate
Methyl (2beta,3beta,5alpha,12beta,19alpha)-3-hydroxy-6,7-didehydroaspidospermidine-3-carboxylate
methyl (1S,14S,15S)-15-ethyl-17-methyl-12-oxo-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
methyl (1S,11S,17R,18R)-18-[(1R)-1-methoxyethyl]-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,9-tetraene-10-carboxylate
Tert-butyldifluorotris(trimethylsilyl)methylsilane
methyl (1S,9S,12R,16S,18R,21R)-12-oxido-2-aza-12-azoniahexacyclo[14.2.2.19,12.01,9.03,8.016,21]henicosa-3,5,7-triene-18-carboxylate
1-Pentamethyldisilanyloxy-4-pentamethyldisilanylbenzene
(7Z)-7-ethylidene-1-methoxy-5-methylspiro[11-oxa-5-azatricyclo[6.3.1.04,9]dodecane-2,3-indole]-2-one
1-lauroyl-sn-glycerol 3-phosphate
A 1-acyl-sn-glycerol 3-phosphate having lauroyl (dodecanoyl) as the 1-O-acyl group.
(3R)-3-hydroxy-2,3-dihydrotabersonine
A monoterpenoid indole alkaloid obtained by formal hydration across the 2,3-double bond of tabersonine.
(+)-Minovincinine
A monoterpenoid indole alkaloid that is (+)-vincadifformine which carries a hydroxy group at position 19S. A natural product found in several plant species including Alstonia venenata and Catharanthus trichophyllus.
(1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid methyl ester
15beta-stemmadenine
A monoterpenoid indole alkaloid with forumula C21H26N2O3, isolated from the fruits of Tabernaemontana heyneana.
JZP-430
JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL)[1].
7-chloro-6,9a-dimethyl-6-(4-methylpent-3-en-1-yl)-1h,3h,5h,5ah,7h,8h,9h,9bh-naphtho[1,2-c]furan-1,9-diol
7'-ethylidene-1-methoxy-5'-methyl-11'-oxa-5'-azaspiro[indole-3,2'-tricyclo[6.3.1.0⁴,⁹]dodecan]-2-one
methyl 15-ethyl-13-(hydroxymethyl)-3,17-diazapentacyclo[12.3.1.0²,¹⁰.0⁴,⁹.0¹²,¹⁷]octadeca-2,4,6,8-tetraene-13-carboxylate
(1s,2s,4e,6r,7r,8s,9r,13r)-7-hydroxy-6,13-dimethoxy-4,11,11-trimethyl-12-oxatricyclo[6.3.2.0¹,⁹]tridec-4-en-2-yl acetate
1-{20-hydroxy-16-methyl-15-oxa-1,11-diazahexacyclo[15.3.1.0⁴,¹².0⁴,²⁰.0⁵,¹⁰.0¹³,¹⁸]henicosa-5,7,9-trien-11-yl}ethanone
(1r,9s,10s,12r,13z,18r)-13-ethylidene-18-(methoxycarbonyl)-8-methyl-8,15-diazapentacyclo[10.5.1.0¹,⁹.0²,⁷.0¹⁰,¹⁵]octadeca-2,4,6-trien-15-ium-15-olate
(2s,4s)-5,7-dimethoxy-8-(3-methylbut-2-en-1-yl)-2-phenyl-3,4-dihydro-2h-1-benzopyran-4-ol
14-(chloromethyl)-13,14-dihydroxy-5,9-dimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecane-5-carbaldehyde
methyl 2-{6'-ethyl-2-hydroxy-3',5',6',7',8',8'a-hexahydro-2'h-spiro[indole-3,1'-indolizin]-7'-yl}prop-2-enoate
methyl 15-hydroxy-2,12-diazahexacyclo[14.2.2.1⁹,¹².0¹,⁹.0³,⁸.0¹⁶,²¹]henicosa-3,5,7-triene-18-carboxylate
methyl (16e)-16-ethylidene-2-(hydroxymethyl)-4,14-diazatetracyclo[12.2.2.0³,¹¹.0⁵,¹⁰]octadeca-3(11),5,7,9-tetraene-2-carboxylate
methyl (13e)-13-ethylidene-10-hydroxy-8-methyl-8,15-diazapentacyclo[10.5.1.0¹,⁹.0²,⁷.0⁹,¹⁵]octadeca-2,4,6-triene-18-carboxylate
methyl (1s,14s,15s)-15-ethyl-17-methyl-12-oxo-10,17-diazatetracyclo[12.3.1.0³,¹¹.0⁴,⁹]octadeca-3(11),4,6,8-tetraene-18-carboxylate
methyl 17-ethyl-6-hydroxy-3,13-diazapentacyclo[13.3.1.0²,¹⁰.0⁴,⁹.0¹³,¹⁸]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
(1s,4s,5r,9s,10r,13s,14s)-14-(chloromethyl)-13,14-dihydroxy-5,9-dimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadecane-5-carbaldehyde
methyl (1s,11s,17r,18s)-18-[(1r)-1-methoxyethyl]-8,14-diazapentacyclo[9.5.2.0¹,⁹.0²,⁷.0¹⁴,¹⁷]octadeca-2,4,6,9-tetraene-10-carboxylate
methyl (1s,14s,15s,18r)-15-ethyl-17-methyl-12-oxo-10,17-diazatetracyclo[12.3.1.0³,¹¹.0⁴,⁹]octadeca-3(11),4,6,8-tetraene-18-carboxylate
6,7-dihydroxy-7a-(3-hydroxyprop-1-en-2-yl)-3,3,5-trimethyl-hexahydroindeno[4,3a-b]oxiren-2-yl 2-methylpropanoate
(2z)-2-[(5s,7r,9s)-14-hydroxy-9-methoxy-4-methyl-4,10-diazatetracyclo[8.6.1.0⁵,¹⁷.0¹¹,¹⁶]heptadeca-1(17),11,13,15-tetraen-7-yl]but-2-enal
methyl (3r,7r,8s)-7-ethyl-5-methyl-10-oxo-5,12-diazatetracyclo[9.7.0.0³,⁸.0¹³,¹⁸]octadeca-1(11),13,15,17-tetraene-3-carboxylate
methyl (1s,17r,18s)-17-(2-hydroxyethyl)-3,13-diazapentacyclo[13.3.1.0²,¹⁰.0⁴,⁹.0¹³,¹⁸]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
1-[12-(2-hydroxyethylidene)-10-(hydroxymethyl)-8,14-diazapentacyclo[9.5.2.0¹,⁹.0²,⁷.0¹⁴,¹⁷]octadeca-2,4,6-trien-8-yl]ethanone
(1'r,2's,3s,4's,7's,9'r)-1,9'-dimethyl-2'-(2-oxopropyl)-10'-oxa-8'-azaspiro[indole-3,5'-tricyclo[5.4.0.0⁴,⁸]undecan]-2-one
(2r)-2-{2-[3-(hydroxymethyl)-4-methoxy-2,6-dimethylphenyl]ethyl}-2-methylchromen-6-ol
methyl (3as,4r,7ar)-4-{[(2s)-1-methoxy-1-oxopropan-2-yl]oxy}-3a,4,5,7a-tetrahydrospiro[1,3-benzodioxole-2,1'-cyclohexane]-6-carboxylate
3-(acetyloxy)-2-[(1r,2r,3s,4s)-4-ethenyl-2-hydroxy-4-methyl-3-(prop-1-en-2-yl)cyclohexyl]-2-hydroxypropyl acetate
methyl 2-[(3r,6'r,7'r,8'ar)-6'-ethyl-2-hydroxy-3',5',6',7',8',8'a-hexahydro-2'h-spiro[indole-3,1'-indolizin]-7'-yl]prop-2-enoate
6-[(2r)-2-hydroxydodecan-2-yl]-4-methoxy-2-oxopyran-3-carboxylic acid
methyl (2e)-3-methoxy-2-{3-methyl-1h,2h,3h,4h,6h,7h,12h,12bh-indolo[2,3-a]quinolizin-2-yl}prop-2-enoate
7-(1-chloro-2-hydroxyethyl)-2-hydroxy-1,4b,7,10a-tetramethyl-4,4a,5,6,8,8a,9,10-octahydrophenanthren-3-one
4-hydroxy-6-(2,4,8-trihydroxy-3,7,9-trimethylundeca-5,9-dien-1-yl)-5,6-dihydropyran-2-one
methyl 18-(1-methoxyethyl)-8,14-diazapentacyclo[9.5.2.0¹,⁹.0²,⁷.0¹⁴,¹⁷]octadeca-2,4,6,9-tetraene-10-carboxylate
6-(acetyloxy)-5-(2-carboxyethyl)-1,4a,6-trimethyl-hexahydro-2h-naphthalene-1-carboxylic acid
[(1s,9s,10s,11r,12z,17s)-12-(2-hydroxyethylidene)-8,14-diazapentacyclo[9.5.2.0¹,⁹.0²,⁷.0¹⁴,¹⁷]octadeca-2,4,6-trien-10-yl]methyl acetate
2-[2-(acetyloxy)ethylidene]-4,9-dihydroxy-6,10-dimethylundeca-5,10-dien-1-yl acetate
1-(7-hydroxy-6-isopropyl-2-methylnaphthalen-1-yl)-4-methyl-1-oxopent-3-en-2-yl acetate
10-hydroxycoronaridine
{"Ingredient_id": "HBIN000140","Ingredient_name": "10-hydroxycoronaridine","Alias": "NA","Ingredient_formula": "C21H26N2O3","Ingredient_Smile": "CCC1CC2CC3(C1N(C2)CCC4=C3NC5=C4C=C(C=C5)O)C(=O)OC","Ingredient_weight": "354.4 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "14211;14212","PubChem_id": "52948159","DrugBank_id": "NA"}
11-hydroxycoronaridine
{"Ingredient_id": "HBIN000441","Ingredient_name": "11-hydroxycoronaridine","Alias": "NA","Ingredient_formula": "C21H26N2O3","Ingredient_Smile": "CCC1CC2CC3(C1N(C2)CCC4=C3NC5=C4C=CC(=C5)O)C(=O)OC","Ingredient_weight": "354.4 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "15834","PubChem_id": "44566751","DrugBank_id": "NA"}
15α-hydroxykopsinine
{"Ingredient_id": "HBIN001613","Ingredient_name": "15\u03b1-hydroxykopsinine","Alias": "NA","Ingredient_formula": "C21H26N2O3","Ingredient_Smile": "COC(=O)C1CC23CCCN4C2C5(C1(CC3O)NC6=CC=CC=C65)CC4","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "10292","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
17-chloro-13,16β-dihydroxy-ent-kauran-19-al
{"Ingredient_id": "HBIN002010","Ingredient_name": "17-chloro-13,16\u03b2-dihydroxy-ent-kauran-19-al","Alias": "NA","Ingredient_formula": "C20H31ClO3","Ingredient_Smile": "CC1(CCCC2(C1CCC34C2CCC(C3)(C(C4)(CCl)O)O)C)C=O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "3548","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
19-heyneanine
{"Ingredient_id": "HBIN002189","Ingredient_name": "19-heyneanine","Alias": "NA","Ingredient_formula": "C21H26N2O3","Ingredient_Smile": "CC(C1CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "36126","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
beta-yohimbine
{"Ingredient_id": "HBIN018355","Ingredient_name": "beta-yohimbine","Alias": "NA","Ingredient_formula": "C21H26N2O3","Ingredient_Smile": "COC(=O)C1C(CCC2C1CC3C4=C(CCN3C2)C5=CC=CC=C5N4)O","Ingredient_weight": "354.4 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "6233","PubChem_id": "5458418","DrugBank_id": "NA"}
