Exact Mass: 340.0269104
Exact Mass Matches: 340.0269104
Found 239 metabolites which its exact mass value is equals to given mass value 340.0269104,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
D-myo-Inositol 1,4-bisphosphate
D-myo-Inositol 1,4-bisphosphate belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. D-myo-Inositol 1,4-bisphosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). D-myo-Inositol 1,4-bisphosphate is a substrate for several proteins including inositol polyphosphate 1-phosphatase, phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, skeletal muscle and kidney enriched inositol phosphatase, and type I inositol-1,4,5-trisphosphate 5-phosphatase. 1D-Myo-inositol 1,4-bisphosphate is a substrate for Inositol polyphosphate 1-phosphatase, Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, Skeletal muscle and kidney enriched inositol phosphatase and Type I inositol-1,4,5-trisphosphate 5-phosphatase. [HMDB]
alpha-D-Glucose 1,6-bisphosphate
Glucose 1,6-diphosphate (G-1,6-P2) is considered to be a major regulator of carbohydrate metabolism. It has been demonstrated that G-1,6-P2 is a potent activator (deinhibitor) of skeletal muscle phosphofructokinase (PFK) and phosphoglucomutase, while being an inhibitor of hexokinase (see Ref. 2). In addition, G-1,6-P2 has been shown to inhibit 6-phosphogluconate dehydrogenase in various rat tissues and fructose 1,6-bisphosphatase in bovine liver. Various factors and conditions affect the tissue content of G-1,6-P2. Specifically, anoxia induces a rapid fall in the content of G-l,6-P2 in the brain. Glucose 1,6-diphosphate has been recognized as a regulatory signal implicated in the control of metabolism, oxygen affinity of red cells, and other cellular functions. The levels of G 1,6-P2 are reduced in the liver and in the muscle of rats with experimentally induced diabetes. In muscle of genetically dystrophic mice, a decrease in the levels of G 1,6-P2 has been found, probably resulting from enhancement of glucose 1,6-P2 phosphatase activity. G 1,6-P2 is an inhibitor of hexokinase and its level is increased significantly after 5 min of exercise (~25\\%) and then decreased continuously. G 1,6-P2 is a potent allosteric activator of phosphofructokinase, and is markedly decreased in muscles of patients with glycogenosis type VII (muscle phosphofructokinase deficiency) and type V (muscle phosphorylase deficiency). Chronic alcohol intake produces an increase in the concentration of G 1,6-P2 in human muscle before the first sign of myopathy appears. When myopathy is present the level decreases to be similar to healthy humans. These changes could contribute to the decline in skeletal muscle performance (PMID:1449560, 2018547, 2003594, 3407759). Glucose 1,6-diphosphate is considered to be a major regulator of carbohydrate metabolism. It has been demonstrated that G-1,6-P2 is a potent activator (deinhibitor) of skeletal muscle phosphofructokinase (PFK) and phosphoglucomutase, while being an inhibitor of hexokinase (see Ref. 2). In addition, G-1,6 P2 has been shown to inhibit 6-phosphogluconate dehydrogenase in various rat tissues and fructose 1,6-bisphosphatase in bovine liver. Various factors and conditions affect the tissue content of G-1,6-P2. Specifically, anoxia induce a rapid fall in the content of G-l,6-P2 in brain. Glucose 1,6-diphosphate (G 1,6-P2 )have been recognized as a regulatory signal implicated in the control of metabolism, oxygen affinity of red cells and other cellular functions. The levels of G 1,6-P2 are reduced in the liver and in the muscle of rats with experimentally induced diabetes. In muscle of genetically dystrophic mice a decrease in the levels of G 1,6-P2 has been found, probably resulting from enhancement of glucose 1,6-P2 phosphatase activity. G 1,6-P2 is an inhibitor of hexokinase and its level is increased significantly after 5 min of exercise (~ 25\\%) and then decreased continuously. G 1,6-P2 is a potent allosteric activator of phosphofructokinase, and is markedly decreased in muscles of patients with glycogenosis type VII (muscle phosphofructokinase deficiency) and type V (muscle phosphorylase deficiency). Acquisition and generation of the data is financially supported in part by CREST/JST.
Fructose 1,6-bisphosphate
D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents C - Cardiovascular system > C01 - Cardiac therapy D007155 - Immunologic Factors D020011 - Protective Agents KEIO_ID F008
Bis(4-nitrophenyl) hydrogen phosphate
D004791 - Enzyme Inhibitors KEIO_ID B069
D-Fructose 2,6-bisphosphate
D-Fructose 2,6-bisphosphate (CAS: 77164-51-3), also known as phosphofructokinase activator, belongs to the class of organic compounds known as pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. D-Fructose 2,6-bisphosphate is a regulatory molecule controlling the activity of the enzyme phosphofructokinase-1 or PFK1 (in mammals). PFK1, in turn, is the key regulatory enzyme in the central metabolic pathway glycolysis. D-Fructose 2,6-bisphosphate has the effect of increasing the activity of PFK1, thus increasing the rate at which the principle food molecule glucose is broken down. At the same time, this regulatory molecule also inhibits the opposing enzyme (FBPase1) in the reverse pathway (gluconeogenesis) so that the synthesis of glucose is not taking place in the same cell where glucose is being broken down (which would be wasteful). D-Fructose 2,6-bisphosphate is a regulatory molecule controlling the activity of the enzyme Phosphofructokinase-1 or PFK1 (in mammals). PFK1, in turn, is the key regulatory enzyme in the central metabolic pathway Glycolysis. D-Fructose 2,6-bisphosphate has the effect of increasing the activity of PFK1, thus increasing the rate at which the principle food molecule glucose is broken down. At the same time, this regulatory molecule also inhibits the opposing enzyme (FBPase1) in the reverse pathway (gluconeogenesis) so that the synthesis of glucose is not taking place in the same cell where glucose is being broken down (which would be wasteful) . [HMDB] KEIO_ID F010
D-myo-Inositol 1,3-bisphosphate
D-myo-Inositol 1,3-bisphosphate, also known as inositol 1,3-diphosphate, belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. D-myo-Inositol 1,3-bisphosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). D-myo-Inositol 1,3-bisphosphate can be biosynthesized from inositol 1,3,4-trisphosphate through the action of the enzyme type II inositol 3,4-bisphosphate 4-phosphatase. The enzyme phosphatidylinositol 3-kinase (EC 2.7.1.137) catalyzes the production of this metabolite from 1-phosphatidyl-D-myo-inositol. D-myo-Inositol 1,3-bisphosphate is an intermediate in inositol phosphate metabolism. 1D-Myo-inositol 1,3-bisphosphate is an intermediate in inositol phosphate metabolism. The enzyme phosphatidylinositol 3-kinase [EC:2.7.1.137] catalyzes the production of this metabolite from 1-Phosphatidyl-D-myo-inositol. [HMDB]
D-myo-Inositol 3,4-bisphosphate
D-myo-Inositol 3,4-bisphosphate belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. D-myo-Inositol 3,4-bisphosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). In humans, D-myo-inositol 3,4-bisphosphate participates in a number of enzymatic reactions. In particular, D-myo-inositol 3,4-bisphosphate can be biosynthesized from inositol 1,3,4-trisphosphate through the action of the enzyme inositol polyphosphate 1-phosphatase. D-myo-Inositol 3,4-bisphosphate is an intermediate in inositol phosphate metabolism. D-myo-Inositol 3,4-bisphosphate is converted from D-myo-inositol-3-phosphate via inositol polyphosphate-4-phosphatase (EC 3.1.3.66). 1D-myo-Inositol 3,4-bisphosphate is an intermediate in inositol phosphate metabolism. 1D-myo-Inositol 3,4-bisphosphate is converted from 1D-myo-inositol-3-phosphate via inositol polyphosphate-4-phosphatase [EC:3.1.3.66]. [HMDB]
Asparenomycin A
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D013845 - Thienamycins D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
Fructose 1,6-bisphosphate
Fructose 1,6-bisphosphate is fructose sugar or fructosephosphate that has been phosphorylated on carbons 1 and 6. The beta-D-form of this compound is very common in cells. The vast majority of glucose and fructose entering a cell is converted to fructose 1,6-bisphosphate at some point. Fructose 1,6-bisphosphate is a key component in the glycolysis metabolic pathway and is produced by phosphorylation of fructose 6-phosphate The enzyme phosphofructokinase uses ATP to transfer a phosphate group to fructose 6-phosphate to form fructose 1, 6-bisphosphate fructose. The enzyme aldolase splits fructose 1,6-bisphosphate into two sugars that are isomers of each other. These two sugars are dihydroxyacetone phosphate and glyceraldehyde phosphate. Fructose 1,6-bisphosphate is an allosteric activator of pyruvate kinase. The hydrolysis of fructose 1,6-bisphosphate is catalized by Fructose-1,6-bisphosphatase (fru-1,6-P2ase, EC 3.1.3.11) to fructose 6-phosphate and inorganic phosphate and provides a mechanism to permit the reversal of the glycolysis reaction (catalyzed by 6-phosphofructo-1-kinase).(OMIM) [HMDB]. D-Fructose 1,6-bisphosphate is found in many foods, some of which are garden cress, cascade huckleberry, wild celery, and devilfish. D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents C - Cardiovascular system > C01 - Cardiac therapy D007155 - Immunologic Factors D020011 - Protective Agents
D-Tagatose 1,6-bisphosphate
D-Tagatose 1,6-bisphosphate is an intermediate in galactose metabolism. [HMDB] D-Tagatose 1,6-bisphosphate is an intermediate in galactose metabolism.
Grevilline B
Grevilline B is found in mushrooms. Grevilline B is a pigment from Suillus grevillei (larch bolete) Valrubicin is a semisynthetic analog of the anthracycline doxorubicin, and is administered by infusion directly into the bladder. Pigment from Suillus grevillei (larch bolete)
Salvianolic acid D
Salvianolic acid D is a polyphenol metabolite detected in biological fluids (PMID: 20428313). A polyphenol metabolite detected in biological fluids [PhenolExplorer]
D-Mannose 1,6-bisphosphate
This compound belongs to the family of Hexose Phosphates. These are carbohydrate derivatives containing an hexose substituted by one or more phosphate groups.
Sulforaphane-N-acetylcysteine
Sulforaphane-N-acetylcysteine (SFN-NAC) is a metabolite of sulforophane which is a metabolite of glucoraphanin which is found in cauliflower and broccoli sprouts (PMID: 16166336; PMID: 21372038). It is excreted in urine. Glucoraphanin is a glucosinolate compound that is converted in the gut to sulforaphane, an isothiocyanate, by the action of myrosinase enzymes from the plants (PMID: 21372038). Sulforaphane blocks the initiation stage in carcinogenesis by inhibiting enzymes that convert procarcinogens to carcinogens and by inducing phase 2 enzymes that detoxify carcinogens and facilitate their excretion from the body.
Sulforaphane-N-acetyl-cysteine
1,6-Di-O-phosphono-D-fructose
Fructose-1,6-diphosphate
Aflatoxin B1 aldehyde
[(2R,3R)-2,3,5-Trihydroxy-4-oxo-6-phosphonooxyhexyl] dihydrogen phosphate
Thujan-3-ol
Pulcherrimin
N-{[(4-Chloroanilino)carbonyl]oxy}-5-nitrothiophene-3-carboximidamide
5,7-dichloro-1,6-dihydroxy-3-methoxy-8-methyl-9H-xanthen-9-one|5,7-dichloro-3-O-methylnorlichexanthone
C15H10Cl2O5 (339.99052700000004)
2,4-di-(3,4-methylenedioxyphenyloxy)-furan; premnalatin|Premnalatin
1-(ethoxycarbonyl)-5-hydroxyanthraquinone-3-carboxylic acid|4-(ethoxycarbonyl)-9,10-dihydro-8-hydroxy-9,10-dioxoanthracene-2-carboxylic acid|juglanthraquinone A
Atromentic acid|Atromentsaeure|[3-hydroxy-4-(4-hydroxy-phenyl)-5-oxo-5H-furan-2-ylidene]-(4-hydroxy-phenyl)-acetic acid
2,5-Dichloro-1,3,6-trihydroxy-8-methylxanthone-3-Me ether
C15H10Cl2O5 (339.99052700000004)
4,5-Dichloronorlichexanthone-3-Me ether
C15H10Cl2O5 (339.99052700000004)
2-Methyl-2-(4-hydroxy-4-methylpentyl)-7-bromo-2H-1-benzopyran-6-ol
C16H21BrO3 (340.06739760000005)
2,5-Dihydroxy-3-(3,4,5-trihydroxyphenyl)-6-phenyl-1,4-benzoquinone
Harden-Young ester
D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents C - Cardiovascular system > C01 - Cardiac therapy D007155 - Immunologic Factors D020011 - Protective Agents The furanose form of D-fructose 1,6-bisphosphate. A D-fructofuranose 1,6-bisphosphate with a beta-configuration at the anomeric position.
Valstar
Salvianolic acid D
Versicolorin B
An organic heteropentacyclic compound that is 2,3,3a,12a-tetrahydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione carrying three hydroxy substituents at positions 4, 6 and 8.
Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate
C13H15F3O5S (340.05922560000005)
dimethyl(3,3,4,4,5,5,6,6,6-nonafluorohexyl)chlorosilane
C8H10ClF9Si (340.00965579999996)
2-(Trifluoromethyl)-1,3-bis-(dimethylamino)-trimethinium hexafluorophosphate
1,2,4-TRIS(METHANESULFONYLOXY)BUTANE
C7H16O9S3 (339.99564460000005)
[4-(4-CHLORO-BENZYL)-PIPERAZIN-1-YL]-ACETIC ACID DIHYDROCHLORIDE
3,3-dimethyl-7-oxo-6-(2-(thiophen-3-yl)acetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
tert-butyl 3-bromo-5-nitro-1H-indole-1-carboxylate
C13H13BrN2O4 (340.00586380000004)
2-(6-bromoquinolin-4-yl)-1-(6-methylpyridin-2-yl)ethanone
Methyl (2R)-2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate
2-ETHOXY-5-(PYRIDINE-2-CABOXAMIDO) BENZENE-1-SULFONYL CHLORIDE
Melphalan hydrochloride
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
2,3-Diphenyl-5-(2-thienyl)tetrazoliuM Chloride
C17H13ClN4S (340.05494080000005)
Ethyl 6,7-dichloro-3-(trifluoromethyl)-1,4-dihydroquinoxaline-2-carboxylate
C12H9Cl2F3N2O2 (339.99931499999997)
3-Bromo-5-(methoxycarbonyl)benzeneboronic acid pinacol ester
C14H18BBrO4 (340.04814380000005)
2-(7-bromoquinolin-4-yl)-1-(6-methylpyridin-2-yl)ethanone
Minodronic acid monohydrate
D050071 - Bone Density Conservation Agents > D004164 - Diphosphonates
Fenoprofen CalciuM Salt Dihydrate
C15H14O3.1/2Ca.H2O (340.0300356)
Propanoic acid,2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, sodium salt (1:1)
4-(1,3-benzodioxol-5-ylmethyl)-2,3-dihydro-1H-quinoxaline
Methyl (2S)-2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate
ethyl 4-(5-bromo-2-hydroxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
C13H13BrN2O4 (340.00586380000004)
6-[(5-bromotriazolo[4,5-b]pyrazin-3-yl)methyl]quinoline
1H-PYRROLO[2,3-B]PYRIDINE, 1-[(4-METHYLPHENYL)SULFONYL]-5-(TRIFLUOROMETHYL)-
N-[(2-chlorophenyl)carbamoyl]-3-hydroxynaphthalene-2-carboxamide
C18H13ClN2O3 (340.06146580000006)
(2-Bromophenyl)(diphenyl)phosphine
C18H14BrP (340.00164340000003)
3H-Indol-3-one,5-dromo-2-1,3-dihydro-3-oxo-2H-indol-2-ylidene-1,2-dihydro
2-ETHOXY-5-[(PYRIDINE-3-CARBONYL)-AMINO]-BENZENESULFONYL CHLORIDE
L-Cystine, 1,1-dimethyl ester, hydrochloride
C8H18Cl2N2O4S2 (340.00850080000004)
9,10-Dimethoxyanthracene-2-Sulfonic Acid Sodium Salt
S-(Trifluoromethyl)dibenzothiophenium tetrafluoroborate
Mercurate(1-), (4-carboxylatophenyl)hydroxy-
C7H5HgO3.H (340.00232459999995)
(S)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL
C7H16O9S3 (339.99564460000005)
1,6-Di-O-phosphono-D-fructose
C26170 - Protective Agent > C2459 - Chemoprotective Agent > C2080 - Cytoprotective Agent D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents D007155 - Immunologic Factors D020011 - Protective Agents
D,L-Sulforaphane N-Acetyl-L-cysteine
3-chloro-6-methoxy-2,4-dimethyl-N-(3-pyridinylmethyl)benzenesulfonamide
C15H17ClN2O3S (340.06483620000006)
7-Chloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4-quinazolinone
C15H8ClF3N2O2 (340.02263739999995)
(5Z)-3-(1,1-dioxothiolan-3-yl)-5-(pyridin-3-ylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one
[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-hydroxy-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
C9H13N2O10P (340.03078080000006)
1-(5-Phospho-beta-d-ribofuranosyl)barbituric acid
C9H13N2O10P (340.03078080000006)
(2Z)-5-Bromo-2,3-biindole-2,3(1H,1H)-dione ammoniate
2,3-DI-O-Sulfo-alpha-D-glucopyranose
C6H12O12S2 (339.97701920000003)
2-Chloro-6-(2-furyl)-9-[(4-methoxyphenyl)methyl]purine
p-Hydroxymercuribenzoate
C7H6HgO3- (340.00232459999995)
D010575 - Pesticides > D005659 - Fungicides, Industrial > D010663 - Phenylmercury Compounds D004791 - Enzyme Inhibitors > D006902 - Hydroxymercuribenzoates D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors D004791 - Enzyme Inhibitors > D008626 - Mercuribenzoates
(4S,8R)-2,13,18,20-tetrahydroxy-7,9-dioxapentacyclo[10.8.0.03,10.04,8.014,19]icosa-1,3(10),5,11,13,17,19-heptaen-16-one
[(2S,3R,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
C9H13N2O10P (340.03078080000006)
(3S,4S,5S,6S)-6-fluoro-4-hydroxy-3-[hydroxy(methyl)phosphoryl]oxy-5-(2-hydroxyprop-2-enoyloxy)cyclohexene-1-carboxylic acid
C11H14FO9P (340.03594560000005)
(3S,4S,5S,6R)-6-fluoro-4-hydroxy-3-[hydroxy(methyl)phosphoryl]oxy-5-(2-hydroxyprop-2-enoyloxy)cyclohexene-1-carboxylic acid
C11H14FO9P (340.03594560000005)
[(2S,3R,4R,5R)-3,4-dihydroxy-5-(2,4,6-trioxo-1,3-diazinan-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
C9H13N2O10P (340.03078080000006)
6-(3,4-Dihydroxybenzylidene)-3-hydroxy-4-(4-hydroxyphenyl)(2H)pyran-2,5(6H)-dione
Fructose-1,6-diphosphate
D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents C - Cardiovascular system > C01 - Cardiac therapy D007155 - Immunologic Factors D020011 - Protective Agents
N-(4-benzamido-2-chlorophenyl)-2-furancarboxamide
C18H13ClN2O3 (340.06146580000006)
3-(diethylsulfamoyl)-N-(1,3,4-thiadiazol-2-yl)benzamide
C13H16N4O3S2 (340.06637859999995)
1,3-Benzothiazole-6-carboxylic acid (2-benzamido-2-oxoethyl) ester
5,6-Dihydroxy-2-deoxyuridine 5-monophosphate
C9H13N2O10P (340.03078080000006)
A pyrimidine 2-deoxyribonucleoside 5-monophosphate having 5,6-dihydroxyuracil as the nucleobase.
methyl 2-[((E)-2-{[(ethoxycarbonyl)amino]carbonyl}-3-oxo-1-butenyl)amino]-3-thiophenecarboxylate
ethyl N-[(E)-[5-chloro-1-(2-chlorophenyl)-3-methylpyrazol-4-yl]methylideneamino]carbamate
C14H14Cl2N4O2 (340.04937639999997)
2-nitro-4-[(E)-[(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl]phenol
[(2S,3R,4S,5R,6R)-2,3,5-trihydroxy-6-(phosphonooxymethyl)oxan-4-yl] dihydrogen phosphate
2-(2,4,5-Trichlorophenoxy)propionic acid trimethylsilyl ester
C12H15Cl3O3Si (339.98560100000003)
Fructose-2,6-diphosphate
A D-fructofuranose 2,6-bisphosphate with a beta-configuration at the anomeric centre.
D-Tagatofuranose 1,6-bisphosphate
The furanose form of D-tagatose 1,6-bisphosphate.
N-Acetyl-S-{[4-(methanesulfinyl)butyl]carbamothioyl}-D-cysteine
alpha-D-fructofuranose 1,6-bisphosphate
A D-fructofuranose 1,6-bisphosphate with an alpha-configuration at the anomeric position.
keto-D-fructose 1,6-bisphosphate
A ketohexose bisphosphate that is D-fructose substituted by phosphate groups at positions 1 and 6.
MNI137
MNI137 is a potent and selective negative allosteric modulator for group II mGluRs. MNI137 has IC50s values of 8.3 and 12.6 nM for human and rat mGlu2 inhibition of glutamate-induced calcium mobilization[1].
SBI-115
SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5[1].
(1r,9r,10s,14s)-3-bromo-12,14-dihydroxy-13-methyl-2,8,11,13-tetraazatetracyclo[7.6.0.0²,⁶.0¹⁰,¹⁴]pentadeca-3,5,11-trien-7-one
2,4-dichloro-3,8-dihydroxy-6-methoxy-1-methylxanthen-9-one
C15H10Cl2O5 (339.99052700000004)
7-(2h-1,3-benzodioxol-5-yl)-4-methoxy-2h-[1,3]dioxolo[4,5-f]chromen-9-one
[(1s,2s,3r,4r,5s,6s)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxyphosphonic acid
7-(7-methoxy-2h-1,3-benzodioxol-5-yl)-2h-[1,3]dioxolo[4,5-g]chromen-8-one
(2s)-7-bromo-2-(4-hydroxy-4-methylpentyl)-2-methylchromen-6-ol
C16H21BrO3 (340.06739760000005)
2,16,18-trihydroxy-7,9-dioxapentacyclo[10.8.0.0³,¹⁰.0⁴,⁸.0¹⁴,¹⁹]icosa-1(12),2,10,14,16,18-hexaene-13,20-dione
6-[(3,4-dihydroxyphenyl)methylidene]-3-hydroxy-4-(4-hydroxyphenyl)pyran-2,5-dione
(4r,8r)-2,4,18-trihydroxy-7,9-dioxapentacyclo[10.8.0.0³,¹⁰.0⁴,⁸.0¹⁴,¹⁹]icosa-1(12),2,10,14,16,18-hexaene-13,20-dione
(5r,6e)-3-[(1e)-2-[(1-hydroxyethylidene)amino]ethenesulfinyl]-6-(1-hydroxypropan-2-ylidene)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
20-hydroxy-9,14-dimethyl-2,6,12,17-tetraoxapentacyclo[11.7.0.0³,¹⁰.0⁴,⁷.0¹⁵,¹⁹]icosa-1(20),3(10),4(7),8,13,15(19)-hexaene-11,18-dione
2,15,18-trihydroxy-7,9-dioxapentacyclo[10.8.0.0³,¹⁰.0⁴,⁸.0¹⁴,¹⁹]icosa-1,3(10),11,14,16,18-hexaene-13,20-dione
7-bromo-2-(4-hydroxy-4-methylpentyl)-2-methylchromen-6-ol
C16H21BrO3 (340.06739760000005)
(2r)-7-bromo-2-(4-hydroxy-4-methylpentyl)-2-methylchromen-6-ol
C16H21BrO3 (340.06739760000005)
11-hydroxy-7,9-dimethoxy-3h-anthra[2,3-c]furan-1,5,10-trione
(4r,8s)-2,16,18-trihydroxy-7,9-dioxapentacyclo[10.8.0.0³,¹⁰.0⁴,⁸.0¹⁴,¹⁹]icosa-1(12),2,10,14,16,18-hexaene-13,20-dione
[2,5-dihydroxy-6-(hydroxymethyl)-3-(sulfooxy)oxan-4-yl]oxidanesulfonic acid
C6H12O12S2 (339.97701920000003)
(6z)-6-[(3,4-dihydroxyphenyl)methylidene]-3-hydroxy-4-(4-hydroxyphenyl)pyran-2,5-dione
2,5-dihydroxy-3-phenyl-6-(3,4,5-trihydroxyphenyl)cyclohexa-2,5-diene-1,4-dione
(4s,8r)-2,16,18-trihydroxy-7,9-dioxapentacyclo[10.8.0.0³,¹⁰.0⁴,⁸.0¹⁴,¹⁹]icosa-1(12),2,10,14,16,18-hexaene-13,20-dione
10,16,18-trihydroxy-3,5-dioxapentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹⁴,¹⁹]icosa-1(12),2(9),10,14,16,18-hexaene-13,20-dione
[3-hydroxy-4-(4-hydroxyphenyl)-5-oxofuran-2-ylidene](4-hydroxyphenyl)acetic acid
5-(4-hydroxyphenyl)-8-oxatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),3,5,10,12-hexaene-3,4,6,11,12-pentol
(4s,8r)-10,16,18-trihydroxy-3,5-dioxapentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹⁴,¹⁹]icosa-1(12),2(9),10,14,16,18-hexaene-13,20-dione
[(2r,3r,4r,5r)-3,4-dihydroxy-2-(hydroxymethyl)-5-[(phosphonooxy)methyl]oxolan-2-yl]oxyphosphonic acid
2,4-dichloro-1,3-dihydroxy-6-methoxy-8-methylxanthen-9-one
C15H10Cl2O5 (339.99052700000004)
[(2e)-3-hydroxy-4-(4-hydroxyphenyl)-5-oxofuran-2-ylidene](4-hydroxyphenyl)acetic acid
(6e)-3-[(1e)-2-[(1-hydroxyethylidene)amino]ethenesulfinyl]-6-(1-hydroxypropan-2-ylidene)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
2,4-dichloro-1,8-dihydroxy-5-methoxy-6-methylxanthen-9-one
C15H10Cl2O5 (339.99052700000004)