Exact Mass: 300.1123
Exact Mass Matches: 300.1123
Found 500 metabolites which its exact mass value is equals to given mass value 300.1123,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Salidroside
Salidroside is a glycoside. Salidroside is a natural product found in Plantago australis, Plantago coronopus, and other organisms with data available. See also: Sedum roseum root (part of); Rhodiola crenulata root (part of). Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.
Desmedipham
CONFIDENCE standard compound; INTERNAL_ID 3738
5-Nitro-2-(3-phenylpropylamino)benzoic acid
D006133 - Growth Substances > D043924 - Angiogenesis Modulating Agents D000970 - Antineoplastic Agents > D020533 - Angiogenesis Inhibitors D006133 - Growth Substances > D006131 - Growth Inhibitors
Phenmedipham
CONFIDENCE standard compound; INTERNAL_ID 3779 D010575 - Pesticides > D006540 - Herbicides D016573 - Agrochemicals
2-(3-Hydroxyphenyl)ethanol 1'-glucoside
2-(3-Hydroxyphenyl)ethanol 1-glucoside is found in fruits. 2-(3-Hydroxyphenyl)ethanol 1-glucoside is a constituent of Sambucus nigra (elderberry). Constituent of Sambucus nigra (elderberry). 2-(3-Hydroxyphenyl)ethanol 1-glucoside is found in fruits.
4-Methoxybenzyl glucoside
4-Methoxybenzyl glucoside is found in fruits. 4-Methoxybenzyl glucoside is present in fennel and marrow (flowers). Present in fennel and marrow (flowers). 4-Methoxybenzyl glucoside is found in herbs and spices and fruits.
1-{2-[(3-Ethylphenyl)amino]-2-oxoethyl}-6-oxo-1,6-dihydropyridine-3-carboxylic acid
Etifoxine
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent N - Nervous system > N05 - Psycholeptics > N05B - Anxiolytics Etifoxine, a non-benzodiazepine GABAergic compound, is a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. Etifoxine reveals anxiolytic and anticonvulsant properties in rodents[1][2][3].
Salidroside
Salidroside is a member of the class of compounds known as O-glycosyl compounds. O-glycosyl compounds are glycoside in which a sugar group is bonded through one carbon to another group via a O-glycosidic bond. Salidroside is soluble (in water) and a very weakly acidic compound (based on its pKa). Salidroside can be found in olive, which makes salidroside a potential biomarker for the consumption of this food product. Salidroside (Rhodioloside) is a glucoside of tyrosol found in the plant Rhodiola rosea. It is thought to be one of the compounds responsible for the antidepressant and anxiolytic actions of this plant, along with rosavin. Salidroside may be more active than rosavin, even though many commercially marketed Rhodiola rosea extracts are standardised for rosavin content rather than salidroside . Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.
3-Butyl-1-(hydroxymethyl)-1-(4-methylphenyl)sulfonylurea
2-(Diethylamino)ethyl 4-amino-5-chloro-2-methoxybenzoate
(3Z,6E)-1-Bromo-2-hydroxy-3,7,11-trimethyldodeca-3,6,10-triene
[1R-(1alpha,4alpha,4aalpha,8abeta)]-4-Bromo-1,2,3,4,4a,5,8,8a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-naphthalenol
Isobrasudol
Phenmedipham
D010575 - Pesticides > D006540 - Herbicides D016573 - Agrochemicals CONFIDENCE standard compound; EAWAG_UCHEM_ID 94
Etifoxine
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent N - Nervous system > N05 - Psycholeptics > N05B - Anxiolytics Etifoxine, a non-benzodiazepine GABAergic compound, is a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. Etifoxine reveals anxiolytic and anticonvulsant properties in rodents[1][2][3].
7-[(4-methoxyphenyl)methyl]-1,3-dimethylpurine-2,6-dione
(Z)-3-(7-hydroxy-5-methoxyphenyl)-2-(6-hydroxy-4-methoxyphenyl)acrylaldehyde|erythraddison B
(3alpha, 4beta, 5beta)-form-3-Bromo-11-eudesmen-5-ol
Me ester,7-Me ether-3,7-Dihydroxy-1,9-dimethyl-2-dibenzofurancarboxylic acid|methyl 7-O-methylnorascomatate
(2beta, 4beta, 5beta)-form-2-Bromo-11-eudesmen-5-ol
1-(2,4-dihydroxy-3-methoxyphenyl)-3-(4-methoxyphenyl)-2-propene-1-one|kukulkanin A
1-[2-(Hydroxymethyl)-2-propenyl]-3-methoxydibenzofuran-2,7-diol
1-<(3S*,3aR*,4R*,7S*,7aS*)-7-bromo-7a-methyl-3-(1-methylethyl)octahydro-1H-inden-4-yl>ethanone|1-[(3S*,3aR*,4R*,7S*,7aS*)-7-bromo-7a-methyl-3-(1-methylethyl)octahydro-1H-inden-4-yl]ethanone|7-Acetyl-4-bromo-1-isopropyl-3alpha-methylindane
10-Me ether-8-Methyltoralactone|8-methyltoralactone 10-methylether
2,4,7-Tri-Me ether-2,3,4,6,7-Pentahydroxyphenanthrene|3,6-Dihydroxy-2,4,7-trimethoxyphenanthren
6-methoxy-5-(4-hydroxy-3-methyl-but-2-enyl)-angelicin|6-methoxy-5-(4-hydroxy-3-methylbut-2-enyl)angelicin
4-[2-(3,3-Dimethyloxiranyl)ethoxy]-7H-furo[3,2-g][1]benzopyran-7-one
6-{5-[(5E)-oct-5-en-7-ynyl]thiophen-2-yl}hex-5-ynoic acid
Phenol, 2-methoxy-5-[(1E)-2-(7-methoxy-1,3-benzodioxol-5-yl)ethenyl]-
6-Hydroxy-5,4-dimethoxy-flavanon|6-hydroxy-5-methoxy-2-(4-methoxy-phenyl)-chroman-4-one
(E)-4,5-dimethoxy-2-(1-methoxy-3-phenylallylidene)cyclopent-4-ene-1,3-dione|4,5-dimethoxy-[(E)-2-(1-methoxy-3-phenyl-2-propen-1-ylidene)]-4-cyclopentene-1,3-dione|methyl linderone|Methyl-linderon|Methyllinderone
1beta-bromo-cycloopposita-4beta-ol|5-bromo-1-isopropyl-2,5a-dimethyl-decahydro-cyclopropa[a]inden-2-ol|5a,7a(H)-1beta-bromo-6,8-cycloeudesma-4beta-ol|6,8-cycloeudesmane
5,10-dihydroxy-8-methoxy-2-propyl-4H-naphtho<1,2-b>pyran-4-one|5,10-dihydroxy-8-methoxy-2-propyl-4H-naphtho[1,2-b]pyran-4-one
3,4-Dihydro-4-(4-methoxyphenyl)-5-hydroxy-7-methoxycoumarin
2R*,4R*-8-hydroxyethyl-7,4-dihydroxy-4,2-epoxyflavane
(6aR,11aR)-9-hydroxy-1,3-dimethoxypterocarpan|erythbidin D
(2S)-2,3-dihydro-2-(3-hydroxy-5-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one|(2S)-3-hydroxy-5,7-dimethoxyflavanone
Pterolinus A
A member of the class of 1-benzofurans that is 1-benzofuran substituted by a hydroxy group at position 5, a methoxy group at position 6, a 3-hydroxy-4-methoxyphenyl group at position 3 and a methyl group at position 2. Isolated from Pterocarpus santalinus, it exhibits anti-inflammatory activity.
2-Propen-1-one, 1-(2,4-dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-,(E)-
2,6-Dimethoxy-3-(3-oxo-3-phenylpropyl)-1,4-benzoquinone
rel-(1aR,2R,3R,7bS)-1a,2,3,7b-tetrahydro-2,3-dihydroxy-5-(2-phenylethyl)-7H-oxireno[f][1]benzopyran-7-one
3-(3,4-Dihydroxyphenyl)-6-methoxy-8-hydroxy-3,4-dihydronaphthalene-1(2H)-one
(2S)-3,4-methylenedioxy-5-methoxy-7-hydroxyflavan|eriocaulin A
5,7-Dihydroxy-2-(4-methoxy-phenyl)-6-methyl-chroman-4-on|5,7-dihydroxy-2-(4-methoxy-phenyl)-6-methyl-chroman-4-one|5,7-dihydroxy-6-methyl-4-methoxydihydroflavone
(1R)-1-O-(beta-D-glucopyranosyl)-1-phenylethylene glycol|2-O-beta-glucosyl-(1R)-phenylethylene glycol|crenulatanoside C
5-Acetoxy-2,8,8-trimethyl-4H,8H-benzo[1,2-b:3,4-b]dipyran-4-one
7-Me,4,5-methylene ether-2,4,5,7-Tetrahydroxyflavan|7-methoxy-2-hydroxy-4,5-methylenedioxyflavan
7-hydroxy-5,6-dimethoxy-2-phenyl-chroman-4-one|7-hydroxy-5,6-dimethoxyflavanone
(2R,4S)-2,4-dihydroxy-2H-furan-(3,4:8,7)-flavan-4-ol
(-)-7,8-dihydro-3,6-dihydroxy-1,7,7,8-tetramethyl-5h-furo-[2,3:5,6]naphtho[1,8-bc]furan-5-one
8-(1,1-Diemthylallyloxy)bergapten|8-(1,1-Dimethylallyloxy)-bergapten|8-(1,1-dimethylallyloxy)bergapten|9-(1,1-dimethyl-allyloxy)-4-methoxy-furo[3,2-g]chromen-7-one|9-[(2-methylbut-3-en-2-yl)oxy]-4-methoxy-7H-furo[3,2-g]chromen-7-one
(R)-(-)-pyridindolol K2|(R)-(?)-pyridindolol K2|16-O-acetylpyridindolol
4-(3,3-dimethyl-oxiranylmethyl)-9-methoxy-furo[3,2-g]chromen-7-one
3,7-dimethoxy-1,9-dimethyldibenzofuran-2-carboxylic acid|ascomatic acid|Di-Me ether-3,7-Dihydroxy-1,9-dimethyl-2-dibenzofurancarboxylic acid
Phellopterin
Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1]. Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1]. Phellopterin is a natural product isolated from Angelica dahurica. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium[1].
1-(beta-Carbolin-1-yl)-3,4,5-trihydroxy-1-pentanone
(+-)-5-Hydroxy-4-7-dimethoxy-flavanon|5-Hydroxy-7,4-dimethoxyisoflavanon|5-hydroxy-7-methoxy-3-(4-methoxy-phenyl)-chroman-4-one
1,7-Bis(hydroxymethyl)-9-methoxyphenanthrene-3,6-diol
ACon1_000808
Icariside D2
Icariside D2 is a glycoside. Icariside D2 is a natural product found in Schisandra propinqua, Cyclopia subternata, and other organisms with data available.
LPRP-Et-97543
NCI60_041532
5-Hydroxy-3-(4-hydroxybenzyl)-7-methoxychroman-4-one is a natural product found in Ledebouria leptophylla with data available.
DESMEDIPHAM
CONFIDENCE standard compound; EAWAG_UCHEM_ID 144
4-Hydroxy-5,7-dimethoxyflavanone
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.021 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.022 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.018
Xylure
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.716 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.718 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.712 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.713
7,4-Dimethoxy-5-hydroxyflavanone
4',?7-?Di-?O-?methylnaringenin is a flavonoid found in Renealmia alpinia[1]. 4',?7-?Di-?O-?methylnaringenin is a flavonoid found in Renealmia alpinia[1].
3,9-dihydroxy-1,4,7,10-tetramethylbenzo[b][1,4]benzodioxepin-6-one
5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-2,3-dihydrochromen-4-one
(E)-1-(3,4-dihydroxy-2,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one
5-hydroxy-7,8-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one
5,7,9-trimethoxy-2-methylbenzo[h]chromen-4-one
4-methoxy-9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
8phiC8SPC (STANDARD)
Auto-extracted from 131001_neg_02.mzML; CONFIDENCE Reference Standard (Level 1); Kindly provided by Jennifer Field, Oregon State University; Synthesis according to P.W. Taylor and G. Nickless, J. Chromotography, 178 (1979) 259-269.
SPA-8C (SAMPLE)
Auto-extracted from 131001_neg_03.mzML; CONFIDENCE Tentative identification: isomers possible (Level 3)
C14H20O7_4-(2-Hydroxyethyl)phenyl beta-D-glucopyranoside
C17H16O5_(3R)-3-(3,4-Dimethoxyphenyl)-8-hydroxy-3,4-dihydro-1H-isochromen-1-one
(3R)-3-(3,4-dimethoxyphenyl)-8-hydroxy-3,4-dihydroisochromen-1-one
(2S,3R,4S,5S,6R)-2-[4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
(2S,3R,4S,5S,6R)-2-[4-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol_major
Homopisatin
2-(3-Hydroxyphenyl)ethanol 1'-glucoside
5,7-Dihydroxy-4'-methoxy-8-methylisoflavanone
5-bromo-1-isopropyl-2,5a-dimethyl-decahydro-cyclopropa[a]inden-2-ol
2-(2-CARBOXYMETHYL-PHENOXY)-3,4-DIMETHYL-BENZOIC ACID
4-[(2-methoxy-4-nitrophenyl)azo]-N,N-dimethyl-Benzenamine
2,4-Pentadien-2-ol,5-(phenylamino)-1-(phenylimino)-, hydrochloride (1:1)
(2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic acid tert-butyl ester
2,2,2-TRIFLUORO-1-(3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL)ETHANONE
1H-PYRROLO[2,3-B]PYRIDIN-4-OL, 2-(3,4,5-TRIMETHOXYPHENYL)-
2-(1,3-Benzodioxol-5-yl)-1-(5-ethyl-2,4-dihydroxyphenyl)ethanone
2-(2-fluoro-4-methanesulfonylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
1-PHENYLAMINO-5-PHENYLIMINO-1,3-PENTADIEN-2-OL HYDROCHLORIDE
Butanoic acid,4-chloro-, 2-(diphenylmethylene)hydrazide
3-Fluoro-4-(methylsulfonyl)phenylboronic Acid Pinacol Ester
8-N-BOC-AMINO-1,5-DIHYDRO-[1,2]DIAZEPINO[4,5,6-CD]INDOL-6-ONE
2-amino-1-(4-aminophenyl)pyrrolo[3,2-b]quinoxaline-3-carbonitrile
2-[[2-methyl-4-[(4-nitrophenyl)azo]phenyl]amino]ethanol
2-ethoxy-2-[(2-nitrophenyl)amino]-1-phenyl-ethanone
(alphaR)-alpha-Hydroxy-N-[2-(4-nitrophenyl)ethyl]benzeneacetamide
N-(7-γ-glutamyl)-α-naphthylamide,N-(γ-L-GLUTAMYL)-1-NAPHTHYLAMIDE
4,4,5,5-TETRAMETHYL-2-(4-TRIFLUOROVINYLOXY-PHENYL)-[1,3,2]DIOXABOROLANE
Benzaldehyde,4-hydroxy-3-methoxy-, 2-[(4-hydroxy-3-methoxyphenyl)methylene]hydrazone
2-(CHLOROMETHYL)-2-METHYL-3-(4-METHYLPHENYL)-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE
(R)-tert-butyl 4-oxo-2-(thiazolidine-3-carbonyl)pyrrolidine-1-carboxylate
2-(4-BUTYLPHENYL)-6-CHLORO-2H-1,2,3-BENZOTRIAZOL-5-AMINE
((Carbonylbis(azanediyl))bis(3,1-phenylene))diboronic acid
3-[(4-fluorophenyl)methyl]-7,7-dimethyl-6,8-dihydrochromene-2,5-dione
(3-CHLORO-PHENYL)-(4-PIPERAZIN-1-YL-PHENYL)-METHANONE
2-(Diethylamino)ethyl 4-amino-5-chloro-2-methoxybenzoate
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists
5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one
N-(2-(3,4-Dichlorophenyl)ethyl)-N-methyl-2-(1-pyrrolidinyl)ethylamine
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(2-hydroxyphenyl)-6,8-dimethyl-, (2S)-
3-(3-Methoxy-4-phenylmethoxyphenyl)-2-oxopropanoic acid
Diethyl (4-hydroxy-2-oxo-4-phenylbutyl)phosphonate
rhodosin
Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy. Salidroside is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.
2-(3-Methoxy-4-methoxyphenyl)-5-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one
4-[1-Methyl-5-(methoxycarbonyl)pentyl]benzenesulfonic acid
S-3-hydroxy-4,4-dimethoxydalbergione
A natural product found in Pterocarpus santalinus.
1-[4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-trimethylsilylpyrimidine-2,4-dione
4-amino-5-[2-amino-3-(1H-imidazol-5-yl)propanoyl]peroxy-5-oxopentanoic acid
4,7-Dihydroxy-N,N,N-trimethyl-4,10-dioxo-3,5,9-trioxa-4lambda~5~-phosphaundecan-1-aminium
[5-(4-Nitrophenyl)-2-furanyl]-(1-piperidinyl)methanone
4-[[(4-Methoxyanilino)-oxomethyl]amino]benzoic acid methyl ester
3-(2,3-dihydro-1,4-benzodioxin-3-yl)-N-(3-hydroxy-2-pyridinyl)propanamide
6-Amino-3-tert-butyl-4-thiophen-2-yl-2,4-dihydroisoxazolo[5,4-b]pyridine-5-carbonitrile
Methyl 4-[2-(3-methoxyphenyl)-2-oxoethoxy]benzoate
2-[[2-(3-Methoxyphenoxy)-1-oxoethyl]amino]benzamide
2-(3,4-Diethoxyphenyl)-5-(2-furanyl)-1,3,4-oxadiazole
(2S,3S)-3,5,7-trihydroxy-6,8-dimethylflavanone
A trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 3, 5 and 7 and methyl groups at positions 6 and 8 (the 2S,3S-stereoisomer). It has been isolated from the buds of Cleistocalyx operculatus and has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2.
1-Prop-2-enyl-5-[1-(3-pyridinylmethylamino)ethylidene]-1,3-diazinane-2,4,6-trione
2-[[(2R)-3-acetyloxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
6,6-Dimethyl-9-thiophen-2-yl-5,7,8a,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8-one
2-[[(2R)-2-acetyloxy-3-hydroxypropoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
3,9-Dihydroxy-1,4,7,10-tetramethylbenzo[b][1,4]benzodioxepin-6-one
NPPB
D006133 - Growth Substances > D043924 - Angiogenesis Modulating Agents D000970 - Antineoplastic Agents > D020533 - Angiogenesis Inhibitors D006133 - Growth Substances > D006131 - Growth Inhibitors
2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol
(2S)-5-hydroxy-4,7-dimethoxyflavanone
A 5-hydroxy-4,7-dimethoxyflavanone that has (S)-configuration.
(2S)-2-hydroxydemethoxymatteucinol
A trihydroxyflavanone that is demethoxymatteucinol with an additional hydroxy group at position 2. Isolated from Pisonia aculeata, it exhibits antitubercular activity.
5-hydroxy-4,7-dimethoxyflavanone
A dimethoxyflavanone that is naringenin in which the hydroxy groups at positions 4 and 7 are replaced by methoxy groups.
Nexinhib20
Nexinhib20 is a specific Rab27a-JFC1 interaction inhibitor with a calculated IC50 of 2.6 μM. Nexinhib20 significantly inhibits superoxide anion production. Nexinhib20 efficiently decreases exocytosis of azurophilic granules in neutrophils stimulated with fMLP, GM-CSF or both. Nexinhib20 has a significant anti-inflammatory activity[1].
5,7-dimethoxy-3-(4-methoxyphenyl)-3h-2-benzofuran-1-one
5-[(1r)-1-(4-hydroxyphenyl)prop-2-en-1-yl]-2,3-dimethoxycyclohexa-2,5-diene-1,4-dione
6,7-dimethoxy-5-methyl-2-oxatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,9,11,13-heptaene-4,12-diol
3-bromo-2a,4a,5,8-tetramethyl-octahydrocyclobuta[d]inden-7-ol
methyl 2-({5-[(r)-hydroxy(phenyl)methyl]pyridin-2-yl}formamido)acetate
(2r,3r)-3-hydroxy-7-methoxy-2-(4-methoxyphenyl)-2,3-dihydro-1-benzopyran-4-one
5,11-dimethoxy-3,13-dimethyl-8-oxatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),3,5,10,12-hexaene-4-carboxylic acid
(3r)-3-(6-methoxy-2h-1,3-benzodioxol-5-yl)-3,4-dihydro-2h-1-benzopyran-7-ol
3-hydroxy-1-methoxy-3-(methoxymethyl)-2h-anthracene-9,10-dione
3-(3,4-dimethoxyphenyl)-8-hydroxy-3,4-dihydro-2-benzopyran-1-one
(3s)-7-hydroxy-3-[(4-hydroxyphenyl)methyl]-5-methoxy-2,3-dihydro-1-benzopyran-4-one
methyl 5-hydroxy-11-methoxy-3,13-dimethyl-8-oxatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),3,5,10,12-hexaene-4-carboxylate
methyl 2-({5-[hydroxy(phenyl)methyl]pyridin-2-yl}formamido)acetate
5-bromo-1,1,2a,5a-tetramethyl-octahydrocyclopropa[f]azulen-2-ol
(2r,3r)-3,5,7-trihydroxy-6,8-dimethyl-2-phenyl-2,3-dihydro-1-benzopyran-4-one
(2r)-7-hydroxy-5-methoxy-2-(4-methoxyphenyl)-2,3-dihydro-1-benzopyran-4-one
(3s,3as,4r,7s,7as)-7-bromo-4,7a-dimethyl-3-(2-methylprop-1-en-1-yl)-hexahydro-1h-inden-4-ol
(2r)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-6-methyl-2,3-dihydro-1-benzopyran-4-one
7-hydroxy-5,6-dimethoxy-2-phenyl-2,3-dihydro-1-benzopyran-4-one
1-(4-bromo-3,3-dimethylcyclohexyl)-3-methylbicyclo[3.1.0]hexan-3-ol
(3s)-5-[(1s,5s)-5-bromo-2,6,6-trimethylcyclohex-2-en-1-yl]-3-methylpent-1-en-3-ol
(2ar,3s,4ar,5s,7s,8r,8as)-3-bromo-2a,4a,5,8-tetramethyl-octahydrocyclobuta[d]inden-7-ol
7,13-dimethoxy-14-methyl-2-oxatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3,5,7,9,12,14-heptaene-4,15-diol
5,14-dimethoxy-8,17-dioxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁶]heptadeca-2,4,6,11,13,15-hexaen-6-ol
6-hydroxy-2-[(2e)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-5-methoxy-6-methylcyclohex-4-ene-1,3-dione
8-imino-3,10,20-triazapentacyclo[11.7.1.0²,⁷.0⁹,²¹.0¹⁴,¹⁹]henicosa-1(20),2(7),9,11,13(21),14(19),15,17-octaen-6-one
(2r,3r,4s,5s,6r)-2-[(2r)-2-hydroxy-2-phenylethoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
4-{[(2s)-3,3-dimethyloxiran-2-yl]methyl}-9-methoxyfuro[3,2-g]chromen-7-one
(1s,2r,4ar,5r,8as)-5-bromo-2-isopropyl-4a,8-dimethyl-2,3,4,5,6,8a-hexahydro-1h-naphthalen-1-ol
(2r)-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-2,3-dihydro-1-benzopyran-4-one
(3r)-3-(2-hydroxy-4-methoxyphenyl)-7-methoxy-2,3-dihydro-1-benzopyran-4-one
(1s,10s)-14,15-dimethoxy-8,17-dioxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁶]heptadeca-2,4,6,11,13,15-hexaen-5-ol
(1r,10r)-13,14-dimethoxy-8,17-dioxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁶]heptadeca-2,4,6,11(16),12,14-hexaen-5-ol
(2e)-2,3-bis(4-hydroxy-3-methoxyphenyl)prop-2-enal
(1s,9s)-11,13-dimethoxy-8,16-dioxatetracyclo[7.7.1.0²,⁷.0¹⁰,¹⁵]heptadeca-2,4,6,10,12,14-hexaen-6-ol
5,10-dihydroxy-8-methoxy-2-propylbenzo[h]chromen-4-one
(2s)-6-hydroxy-5-methoxy-2-(4-methoxyphenyl)-2,3-dihydro-1-benzopyran-4-one
(2s,3r,4s,5s,6r)-2-(4-hydroxy-3,5-dimethylphenoxy)-6-(hydroxymethyl)oxane-3,4,5-triol
2-(hydroxymethyl)-6-[2-(methoxymethyl)phenoxy]oxane-3,4,5-triol
1,5,7-trimethoxy-2,6-phenanthrenediol
{"Ingredient_id": "HBIN001594","Ingredient_name": "1,5,7-trimethoxy-2,6-phenanthrenediol","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "NA","Ingredient_weight": "300.31","OB_score": "NA","CAS_id": "118169-17-8","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "9516","PubChem_id": "NA","DrugBank_id": "NA"}
1-o-β-d-glucopyranosyl-2-(3-hydroxyphenyl)-ethanol
{"Ingredient_id": "HBIN002848","Ingredient_name": "1-o-\u03b2-d-glucopyranosyl-2-(3-hydroxyphenyl)-ethanol","Alias": "NA","Ingredient_formula": "C14H20O7","Ingredient_Smile": "C1=CC(=CC(=C1)O)CCOC2C(C(C(C(O2)CO)O)O)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "8675","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2,3-epoxy-3-prenyl-1,4-naphthoquinone-2-carboxylic acid; me ester
{"Ingredient_id": "HBIN004087","Ingredient_name": "2,3-epoxy-3-prenyl-1,4-naphthoquinone-2-carboxylic acid; me ester","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "NA","Ingredient_weight": "300.31","OB_score": "NA","CAS_id": "133361-29-2","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "8927","PubChem_id": "NA","DrugBank_id": "NA"}
2,5-dihydroxy-6-methyl-7-methoxyflavanone
{"Ingredient_id": "HBIN004629","Ingredient_name": "2,5-dihydroxy-6-methyl-7-methoxyflavanone","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "CC1=C(C=C2C(=C1O)C(=O)CC(O2)(C3=CC=CC=C3)O)OC","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "6035","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2,5-dihydroxy-8-methyl-7-methoxyflavanone
{"Ingredient_id": "HBIN004630","Ingredient_name": "2,5-dihydroxy-8-methyl-7-methoxyflavanone","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "CC1=C(C=C2C(=C1O)C(=O)CC(O2)(C3=CC=CC=C3)O)OC","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "6036","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2′,6 ′-dimethoxy-4,4 ′-dihydroxychalcone
{"Ingredient_id": "HBIN004895","Ingredient_name": "2\u2032,6 \u2032-dimethoxy-4,4 \u2032-dihydroxychalcone","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "COC1=CC(=CC(=C1C(=O)C=CC2=CC=C(C=C2)O)OC)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "6216","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2-carboxymethyl-3-phenyl-2,3-epoxy-1,4-naph-thoquinone
{"Ingredient_id": "HBIN005447","Ingredient_name": "2-carboxymethyl-3-phenyl-2,3-epoxy-1,4-naph-thoquinone","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "CC(=CCC12C(=O)C3=CC=CC=C3C(=O)C1(O2)C(=O)OC)C","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "3181","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2-Carboxymethyl-3-prenyl-2,3-epoxy-1,4-naphthoquinone
{"Ingredient_id": "HBIN005448","Ingredient_name": "2-Carboxymethyl-3-prenyl-2,3-epoxy-1,4-naphthoquinone","Alias": "2-carboxymethyl-3-prenyl-2,3-epoxy-1,4-naphthoquinone","Ingredient_formula": "C17H16O5","Ingredient_Smile": "Not Available","Ingredient_weight": "300.33","OB_score": "20.67711771","CAS_id": "NA","SymMap_id": "SMIT00892","TCMID_id": "30741","TCMSP_id": "MOL002890;MOL006154","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2'-hydroxy-3',5'-diimethoxyflavanone
{"Ingredient_id": "HBIN005739","Ingredient_name": "2'-hydroxy-3',5'-diimethoxyflavanone","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "COC1=CC(=C(C2=C1C(=O)CC(O2)C3=CC=CC=C3)O)OC","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "10012","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
3-(4-hydroxy-3-methoxyphenyl)-2-oxopropylbenzoate
{"Ingredient_id": "HBIN007477","Ingredient_name": "3-(4-hydroxy-3-methoxyphenyl)-2-oxopropylbenzoate","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "COC1=C(C=CC(=C1)CC(=O)COC(=O)C2=CC=CC=C2)O","Ingredient_weight": "300.3 g/mol","OB_score": "9.435784203","CAS_id": "NA","SymMap_id": "SMIT12984","TCMID_id": "NA","TCMSP_id": "MOL012191","TCM_ID_id": "NA","PubChem_id": "91460481","DrugBank_id": "NA"}
3-hydroxymollugin
{"Ingredient_id": "HBIN008727","Ingredient_name": "3-hydroxymollugin","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "NA","Ingredient_weight": "300.31","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "8077","PubChem_id": "NA","DrugBank_id": "NA"}
(3R)-sativanone
{"Ingredient_id": "HBIN009587","Ingredient_name": "(3R)-sativanone","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "COC1=CC(=C(C=C1)C2COC3=C(C2=O)C=CC(=C3)O)OC","Ingredient_weight": "300.3 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "36760","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "5321142","DrugBank_id": "NA"}
4,9-dihydroxy-7h-furo[3,2-g][1]benzopyran-7-one,9ci; 9-o-(1,1-dimethyl-2-propenyl),4-me ether
{"Ingredient_id": "HBIN010153","Ingredient_name": "4,9-dihydroxy-7h-furo[3,2-g][1]benzopyran-7-one,9ci; 9-o-(1,1-dimethyl-2-propenyl),4-me ether","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "NA","Ingredient_weight": "300.31","OB_score": "NA","CAS_id": "57419-90-6","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "7873","PubChem_id": "NA","DrugBank_id": "NA"}
5-hydroxy-4',7-dimethoxydihydroflavone
{"Ingredient_id": "HBIN011611","Ingredient_name": "5-hydroxy-4',7-dimethoxydihydroflavone","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "COC1=CC=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)OC)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "10019","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
(6aR,11aR)-4-methoxymedicarpin
{"Ingredient_id": "HBIN012226","Ingredient_name": "(6aR,11aR)-4-methoxymedicarpin","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "COC1=CC2=C(C=C1)C3COC4=C(C3O2)C=CC(=C4OC)O","Ingredient_weight": "300.3 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "41738","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "14077266","DrugBank_id": "NA"}
7,4'-dihydroxy-2',5'-dimethoxyisoflav-3-ene
{"Ingredient_id": "HBIN012923","Ingredient_name": "7,4'-dihydroxy-2',5'-dimethoxyisoflav-3-ene","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "COC1=CC(=C(C=C1C2=CC3=C(C=C(C=C3)O)OC2)OC)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "5832","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
7-o-methylglabranin
{"Ingredient_id": "HBIN013408","Ingredient_name": "7-o-methylglabranin","Alias": "NA","Ingredient_formula": "C17H16O5","Ingredient_Smile": "COC1=C(C2=C(C(=O)CC(O2)C3=CC=CC=C3)C(=C1)O)OC","Ingredient_weight": "300.3 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "14457","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "13963771","DrugBank_id": "NA"}
