Exact Mass: 297.0436
Exact Mass Matches: 297.0436
Found 264 metabolites which its exact mass value is equals to given mass value 297.0436
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
5-methylthioadenosine (MTA)
5-Methylthioadenosine, also known as MTA or thiomethyladenosine, belongs to the class of organic compounds known as 5-deoxy-5-thionucleosides. These are 5-deoxyribonucleosides in which the ribose is thio-substituted at the 5position by a S-alkyl group. 5-Methylthioadenosine is metabolized solely by MTA-phosphorylase, to yield 5-methylthioribose-1-phosphate and adenine, a crucial step in the methionine and purine salvage pathways, respectively. 5-Methylthioadenosine exists in all living species, ranging from bacteria to humans. 5-Methylthioadenosine (MTA) is a naturally occurring sulfur-containing nucleoside present in all mammalian tissues. Within humans, 5-methylthioadenosine participates in a number of enzymatic reactions. In particular, 5-methylthioadenosine and spermidine can be biosynthesized from S-adenosylmethioninamine and putrescine through the action of the enzyme spermidine synthase. In addition, 5-methylthioadenosine can be converted into 5-methylthioribose 1-phosphate and L-methionine; which is catalyzed by the enzyme S-methyl-5-thioadenosine phosphorylase. It is produced from S-adenosylmethionine mainly through the polyamine biosynthetic pathway, where it behaves as a powerful inhibitory product. For instance, 5-Methylthioadenosine has been shown to influence the regulation of gene expression, proliferation, differentiation, and apoptosis (PMID:15313459). In humans, 5-methylthioadenosine is involved in the metabolic disorder called hypermethioninemia. Outside of the human body, 5-Methylthioadenosine has been detected, but not quantified in several different foods, such as soursops, allspices, summer grapes, alaska wild rhubarbs, and breadfruits. Elevated excretion appears in children with severe combined immunodeficiency syndrome (SCID) (PMID:3987052). Evidence suggests that 5-Methylthioadenosine can affect cellular processes in many ways. 5-Methylthioadenosine can be found in human urine. 5-deoxy-5-methylthioadenosine, also known as S-methyl-5-thioadenosine or mta, is a member of the class of compounds known as 5-deoxy-5-thionucleosides. 5-deoxy-5-thionucleosides are 5-deoxyribonucleosides in which the ribose is thio-substituted at the 5position by a S-alkyl group. 5-deoxy-5-methylthioadenosine is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). 5-deoxy-5-methylthioadenosine can be found in a number of food items such as allspice, sesame, roselle, and bayberry, which makes 5-deoxy-5-methylthioadenosine a potential biomarker for the consumption of these food products. 5-deoxy-5-methylthioadenosine can be found primarily in blood and urine, as well as in human fibroblasts, platelet and prostate tissues. 5-deoxy-5-methylthioadenosine exists in all living species, ranging from bacteria to humans. In humans, 5-deoxy-5-methylthioadenosine is involved in a couple of metabolic pathways, which include methionine metabolism and spermidine and spermine biosynthesis. 5-deoxy-5-methylthioadenosine is also involved in several metabolic disorders, some of which include glycine n-methyltransferase deficiency, methionine adenosyltransferase deficiency, homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism, cblg complementation type, and hypermethioninemia. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2]. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2]. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2].
Albendazole sulfone
Albendazole sulfone is a metabolite of albendazole. Albendazole, marketed as Albenza, Eskazole, Zentel, Andazol and Alworm, is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations. Although this use is widespread in the United States, the U.S. Food and Drug Administration (FDA) has not approved albendazole for this indication. It is marketed by Amedra Pharmaceuticals. Albendazole was first discovered at the SmithKline Animal Health Laboratories in 1972. (Wikipedia) D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics CONFIDENCE standard compound; EAWAG_UCHEM_ID 3647 CONFIDENCE standard compound; INTERNAL_ID 1059
6-nitrobenz(a)pyrene
D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens
L-Cysteinylglycine disulfide
L-Cysteinylglycine disulfide is one of the hydrolysis products of glutathione. Cystinylglycine disulfide is a small peptide replaced cystinylglycine in plasma from patients with homosyctinuria. (PMID: 7333014) [HMDB] L-Cysteinylglycine disulfide is one of the hydrolysis products of glutathione. Cystinylglycine disulfide is a small peptide replaced cystinylglycine in plasma from patients with homosyctinuria. (PMID: 7333014).
2-Chloroticlopidine
2-Chloroticlopidine is only found in individuals that have used or taken Ticlopidine. 2-Chloroticlopidine is a metabolite of Ticlopidine. 2-chloroticlopidine belongs to the family of Thienopyridines. These are heterocyclic compounds containing a thiophene ring fused to a pyridine ring.
Hexahydro-6,7-dihydroxy-5-(hydroxymethyl)-3-(2-hydroxyphenyl)-2H-pyrano[2,3-d]oxazol-2-one
Hexahydro-6,7-dihydroxy-5-(hydroxymethyl)-3-(2-hydroxyphenyl)-2H-pyrano[2,3-d]oxazol-2-one is found in cereals and cereal products. Hexahydro-6,7-dihydroxy-5-(hydroxymethyl)-3-(2-hydroxyphenyl)-2H-pyrano[2,3-d]oxazol-2-one is isolated from the roots of oats (Avena sativa) and corn (Zea mays). Isolated from the roots of oats (Avena sativa) and corn (Zea mays). Hexahydro-6,7-dihydroxy-5-(hydroxymethyl)-3-(2-hydroxyphenyl)-2H-pyrano[2,3-d]oxazol-2-one is found in oat and cereals and cereal products.
N-(3-Pyrene)maleimide
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D004396 - Coloring Agents > D005456 - Fluorescent Dyes D004791 - Enzyme Inhibitors
(2R,5S)-2-(6-Aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol
N-(3,5-Dichloro-4-hydroxyphenyl)-2-hydroxybenzamide
6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole
N-[(2-Chloro-6-fluorobenzyl)oxy]-2-cyano-3-(dimethylamino)acrylamide
1-(8-Bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b]difuran-4-yl)propan-2-amine
Acetylsulfathiazole
CONFIDENCE standard compound; EAWAG_UCHEM_ID 249 CONFIDENCE standard compound; INTERNAL_ID 2010
PRZ_M298
CONFIDENCE Transformation product, tentative ID (Level 3 structure); INTERNAL_ID 2008
Coniothyriomycin|N-(3-Chloro-4-hydroxyphenylacetyl)fumarate
3-O-beta-glucopyranosyl-benzoxazolin-2(3H)-one|benzoxazolin-2(3H)-one-N-beta-glucopyranoside
Methylthioadenosine
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents Adenosine with the hydroxy group at C-5 substituted with a methylthio (methylsulfanyl) group. COVID info from COVID-19 Disease Map D004791 - Enzyme Inhibitors Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2]. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2]. 5'-(Methylthio)adenosine. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=2457-80-9 (retrieved 2024-11-05) (CAS RN: 2457-80-9). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Albendazole sulfone
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
Methylthioadenosine
5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2]. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2]. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2].
1-(2-hydroxyphenylamino)-1-Deoxyglucoside 1,2-carbamate
1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 7-chloro-4-ethyl-7,8-dihydro-4-hydroxy-, (4S)-
2-oxo-1-[4-(trifluoromethyl)benzyl]-1,2-dihydro-3-pyridinecarboxylic acid
5-(2-Methoxyphenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole
6-NITRO-3-PHENYL-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
1-BENZYL-5-(4-CHLOROPHENYL)-2,3-DIHYDRO-4-PYRIDINONE
n-hydroxy-4-[5-(trifluoromethyl)pyridin-2-yl]oxybenzenecarboximidamide
4-(4-CHLORO-PHENYL)-1,4-DIHYDRO-BENZO[4,5]IMIDAZO[1,2-A][1,3,5]TRIAZIN-2-YLAMINE
1-(6-CHLORO-2-HYDROXY-4-PHENYLQUINOLIN-3-YL)ETHANONE
2-(4-CHLOROPHENYL)-8-METHYLQUINOLINE-4-CARBOXYLICACID
1-(2,5-Dichlorophenyl)-3-propeneamido-5-pyrazolone
2-(2-CHLOROPHENYL)-6-METHYLQUINOLINE-4-CARBOXYLICACID
2-(2-Chlorophenyl)-8-methylquinoline-4-carboxylic acid
6-CHLORO-2-(3-METHYLPHENYL)QUINOLINE-4-CARBOXYLICACID
6-Chloro-2-(4-methylphenyl)quinoline-4-carboxylic acid
7-CHLORO-8-METHYL-2-PHENYLQUINOLINE-4-CARBOXYLICACID
8-CHLORO-2-(3-METHYLPHENYL)QUINOLINE-4-CARBOXYLICACID
8-Chloro-2-(2-methylphenyl)quinoline-4-carboxylic acid
1-Nitro-9,10-dioxo-9,10-dihydro-anthracene-2-carboxylic acid
4-[4-(BENZYLOXY)PHENYL]-5-METHYL-4H-1,2,4-TRIAZOLE-3-THIOL
2-methyl-N-[2-oxo-4-(trifluoromethyl)chromen-7-yl]prop-2-enamide
PHENYL2-AZIDO-2-DEOXY-1-THIO-BETA-D-GLUCOPYRANOSIDE
11-Chloro-2,3-dihydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol-1-one
2-(dimethylamino)-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile
2-(2-METHOXYPHENYL)-1,3-DIOXO-2,3-DIHYDRO-1H-ISOINDOLE-5-CARBOXYLIC ACID
2-CHLORO-N-[4-(3-NITRO-PHENYL)-THIAZOL-2-YL]-ACETAMIDE
2-[(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-YL)CARBONYL]BENZENECARBOXYLIC ACID
6-CHLORO-2-(2-METHYLPHENYL)QUINOLINE-4-CARBOXYLICACID
8-(TRIFLUOROMETHOXY)-2-(TRIFLUOROMETHYL)QUINOLIN-4-OL
N-(3,4-dimethyl-1,2-oxazol-5-yl)-4-nitrobenzenesulfonamide
2-CHLOROETHYL-2-ACETYL-2-((3-NITROPHENYL)METHYLENE)ACETATE
6-bromo-5-methoxy-1H-indole-2-carboxylic acid ethyl ester
SKF 86002
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D018501 - Antirheumatic Agents D004791 - Enzyme Inhibitors
N-(1-pyrene)maleimide
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents D004396 - Coloring Agents > D005456 - Fluorescent Dyes D004791 - Enzyme Inhibitors
Tetraammineplatinum(II) hydroxide hydrate (59\\% Pt)
Benzoic acid,4-(benzoylamino)-2-hydroxy-, calcium salt (2:1)
Isopropyl-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide
3-(2-chlorophenyl)-5-nitro-1H-indole-2-carbonitrile
Glybuzole
C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent
{[5-(4-CHLOROPHENYL)-4-ETHYL-4H-1,2,4-TRIAZOL-3-YL]THIO}ACETIC ACID
1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile, 1-[(4-methylphenyl)sulfonyl]-
4-CHLORO-3-HYDROXY-5-(TRIFLUOROMETHYL)-1,1-BIPHENYL-4-CARBONITRILE
ethyl 6-bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylate
methyl 3-(benzenesulfonamido)thiophene-2-carboxylate
1h-indole-2-carboxylic acid, 3-bromo-5-methoxy-, ethyl ester
4-(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)quinoline-6-carbaldehyde
Ethyl 5-chloro-3-(4-chlorophenyl)-1,2,4-triazine-6-carboxylate
5-(3-chlorophenyl)-6-(propylamino)pyrazine-2,3-dicarbonitrile
2-[3-(trifluoromethyl)benzylsulfonyl]thioacetamide
6-(2,3-dichlorophenyl)-3-imino-2-propan-2-yl-1,2,4-triazin-5-amine
(3-((1-(ANILINOCARBONYL)-2-OXOPROPYL)AZO)-2-HYDROXY-5-NITROBENZENE-1-SULPHONATO(3-))CHROMIUM
2,2,2-trichloro-N-(3,7-dimethylocta-1,6-dien-3-yl)acetamide
8-Bromo-4-(2-hydroxyethyl)-5-methoxy-2(1H)-quinolinone
([1-PHENYL-METH-(E)-YLIDENE]-AMINO)-ACETICACIDETHYLESTER
1-(4-bromo-benzyl)-piperidine-4-carboxylic acid hydrochloride
ETHYL 2-(PYRIDIN-2-YL)-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE
2-bromo-3-methylpyridine-5-boronic acid pinacol ester
5-[(Phenoxycarbonyl)amino]-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid
1,3-dimethyl-2-fluoropyridinium toluene-4-sulfonate
6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]pyridine-3-carboxylic acid
2-(3-chlorophenyl)-3-methylquinoline-4-carboxylic acid
2-[4-(6-CHLORO-1,3-BENZOTHIAZOL-2-YL)PIPERAZINO]ETHAN-1-OL
5-(2-METHOXYPHENYL)-4-(4-METHYLPHENYL)-4H-1,2,4-TRIAZOLE-3-THIOL
4-(Chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole
N-(3-(5-Mercapto-1H-tetrazol-1-yl)phenyl)benzamide
METHYL 3-AMINO-4-(PHENYLSULFONYL)THIOPHENE-2-CARBOXYLATE
Propanedioic acid,2-[[(2-chlorophenyl)amino]methylene]-, 1,3-diethyl ester
2-(4-chlorophenyl)-3-methylquinoline-4-carboxylic acid
5-amino-1-[2-nitro-4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile
4,5,7-tri-o-acetyl-2,6-anhydro-3-deoxy-d-lyxo-hept-2-enononitrile,
4-Hydroxy-6-(trifluoromethoxy)-2-(trifluoromethyl)quinoline
diethyl 2-[(4-chloroanilino)methylidene]propanedioate
Vaborbactam
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D065093 - beta-Lactamase Inhibitors C2140 - Adjuvant > C183118 - Beta-lactamase Inhibitor D004791 - Enzyme Inhibitors
(2-chloro-5-nitrophenyl)(2,6-difluorophenyl)Methanone
5-bromo-2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
2-(3-CARBOXY-PROPIONYLAMINO)-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER
methyl (Z)-5-chloro-3-hydroxy-2-methylidene-5-(4-nitrophenyl)pent-4-enoate
ETHYL 7-CHLORO-1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-5-CARBOXYLATE
2-Naphthalenecarboxamide,N-(3-chlorophenyl)-3-hydroxy-
1-(((4-NITROPHENOXY)CARBONYL)OXY)ETHYL ISOBUTYRATE
Tanaproget
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
Cicletanine hydrochloride
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic D045283 - Natriuretic Agents > D004232 - Diuretics
5-Methylthioformycin
D000970 - Antineoplastic Agents > D000903 - Antibiotics, Antineoplastic > D005573 - Formycins
beta-D-Ribofuranose, 1-(6-amino-9H-purin-9-yl)-1-deoxy-5-S-methyl-5-thio-
(E)-3-(2-chloro-6-methylquinolin-3-yl)-1-(furan-2-yl)prop-2-en-1-one
3-(1,3-benzodioxol-5-yl)-4-phenyl-1H-1,2,4-triazole-5-thione
3-[(4-methylphenoxy)methyl]-4-phenyl-1H-1,2,4-triazole-5-thione
(E)-3-(2-chloro-8-methylquinolin-3-yl)-1-(furan-2-yl)prop-2-en-1-one
1-(2,4-Dimethylphenyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)ethanone
4-[(5-Isopropyl-1,3-thiazol-2-YL)amino]benzenesulfonamide
(2S)-2-amino-5-[(2R,3S,4R,5R)-3-fluoro-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-5-oxopentanoic acid
1-{[2-(2,4,6-Trichlorophenoxy)ethyl]amino}propan-2-ol
[[(2E)-7-methylocta-2,6-dienoxy]-oxido-phosphoryl] phosphate
N-[phenyl(1,3-thiazol-2-yl)sulfamoyl]carbamimidate
(5Z)-2-(2-methylanilino)-5-[(1-methylpyrrol-2-yl)methylidene]-1,3-thiazol-4-one
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-thiophenesulfonamide
1-(2-Chloro-6-fluorophenyl)-[1,2,4]triazolo[4,3-a]quinoline
5-[(6-methyl-2-oxo-1H-quinolin-3-yl)methylidene]-1,3-diazinane-2,4,6-trione
N-cyclopropyl-3-methyl-1-phenyl-5-thieno[2,3-c]pyrazolecarboxamide
(7-Methoxy-2-benzofuranyl)-(4-nitrophenyl)methanone
4-Amino-5-[(4-methylphenyl)-oxomethyl]-2-(prop-2-enylamino)-3-thiophenecarbonitrile
2-[(2,5-Dimethylphenyl)methylthio]-5-(3-pyridinyl)-1,3,4-oxadiazole
N-(2-furanylmethyl)-5-methyl-4-phenyl-3-thiophenecarboxamide
4-chloro-N-(4-methyl-2-thiazolyl)-2-nitrobenzamide
2-(3-imidazo[1,5-a]pyridinylthio)-N-(4-methylphenyl)acetamide
N-(2,3-dichlorobenzylidene)-5-methyl-3-isoxazolecarbohydrazide
N-{[(4-methyl-2-pyridinyl)amino]carbonothioyl}-3-phenylacrylamide
N4,N4-dimethyl-N1-(4-nitro-1,1-dioxo-2,5-dihydrothiophen-3-yl)benzene-1,4-diamine
N-(5-methyl-1,3,4-thiadiazol-2-yl)-N-phenyl-2-pyrazinecarboxamide
N-methyl-N-[5-(3-pyridinyl)-1,3,4-thiadiazol-2-yl]-3-pyridinecarboxamide
6-hydroxy-2-methyl-5-(1H-tetraazol-5-ylcarbonyl)-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
3-[(E)-(2-fluorophenyl)methylideneamino]-5-phenyl-1H-imidazole-2-thione
1-(4-Chloro-3,5-dimethyl-1-pyrazolyl)-2-(5-methyl-3-nitro-1-pyrazolyl)ethanone
2-Amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylate
Hexahydro-6,7-dihydroxy-5-(hydroxymethyl)-3-(2-hydroxyphenyl)-2H-pyrano[2,3-d]oxazol-2-one
N(4)-acetylsulfathiazole
A sulfonamide that is benzenesulfonamide substituted by an acetylamino group at position 4 and a 1,3-thiazol-2-yl group at the nitrogen atom. It is a metabolite of sulfathiazole.
MPP+ (iodide)
MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT)[1][2].