Exact Mass: 267.139
Exact Mass Matches: 267.139
Found 94 metabolites which its exact mass value is equals to given mass value 267.139,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Voglibose
Voglibose is only found in individuals that have used or taken this drug. Voglibose (INN and USAN) is an alpha-glucosidase inhibitor used for lowering post-prandial blood glucose levels in people with diabetes mellitus. It is made in India by Ranbaxy Labs and sold under the trade name Volix. [Wikipedia]Alpha-glucosidase inhibitors are saccharides that act as competitive inhibitors of enzymes needed to digest carbohydrates: specifically alpha-glucosidase enzymes in the brush border of the small intestines. The membrane-bound intestinal alpha-glucosidases hydrolyze oligosaccharides, trisaccharides, and disaccharides to glucose and other monosaccharides in the small intestine. Acarbose also blocks pancreatic alpha-amylase in addition to inhibiting membrane-bound alpha-glucosidases. Pancreatic alpha-amylase hydrolyzes complex starches to oligosaccharides in the lumen of the small intestine. Inhibition of these enzyme systems reduces the rate of digestion of complex carbohydrates. Less glucose is absorbed because the carbohydrates are not broken down into glucose molecules. In diabetic patients, the short-term effect of these drugs therapies is to decrease current blood glucose levels: the long term effect is a small reduction in hemoglobin-A1c level. (From Drug Therapy in Nursing, 2nd ed) Voglibose is an organic molecular entity. Voglibose is an alpha-glucosidase inhibitor used for lowering post-prandial blood glucose levels in people with diabetes mellitus. It is made in India by Ranbaxy Labs and sold under the trade name Volix. Voglibose is a valiolamine derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Voglibose binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BF - Alpha glucosidase inhibitors C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent D007004 - Hypoglycemic Agents > D065089 - Glycoside Hydrolase Inhibitors C471 - Enzyme Inhibitor > C2846 - Glucosidase Inhibitor D004791 - Enzyme Inhibitors Voglibose is a derivative of valiolamine, which can inhibit α-glucosidase very well and can act on hyperglycemia.
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,4,6-trimethyl-, diethyl ester
Lysergic acid amide
Diethyl 2,3,4-trimethyl-2,3-dihydropyridine-5,6-dicarboxylate
O-Ethyl S-(2-diisopropylaminoethyl) methylphosphonothioate
VX nerve agent, also known as VX, belongs to the class of organic compounds known as trialkylamines. These are organic compounds containing a trialkylamine group, characterized by exactly three alkyl groups bonded to the amino nitrogen. Based on a literature review a significant number of articles have been published on VX nerve agent. This compound has been identified in human blood as reported by (PMID: 31557052 ). O-ethyl s-(2-diisopropylaminoethyl) methylphosphonothioate is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically O-Ethyl S-(2-diisopropylaminoethyl) methylphosphonothioate is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources. VX is an extremely toxic synthetic chemical compound in the organophosphorus class, specifically, a thiophosphonate. In the class of nerve agents, it was developed for military use in chemical warfare after translation of earlier discoveries of organophosphate toxicity in pesticide research. In its pure form, VX is an oily, relatively non-volatile liquid that is amber-like in colour.[4] Because of its low volatility, VX persists in environments where it is dispersed.[5][6] VX, short for "venomous agent X",[7] is one of the best known of the V nerve agents and originated from pesticide development work at Imperial Chemical Industries (ICI). It was developed further at Porton Down in England during the early 1950s,[8] based on research first done by Gerhard Schrader, a chemist working for IG Farben in Germany during the 1930s.[citation needed] It is now one of a broader V-series of agents which are classified as nerve agents. VX has been allegedly used in warfare and has been used in several assassinations. The brother of North Korean leader Kim Jong Un, Kim Jong Nam, had the substance thrown in his face in Kuala Lumpur International Airport on the 13th February 2017 by two women. He died being rushed to hospital approximately 15 minutes later. The substance is extremely deadly; VX fatalities occur with exposure to tens of milligram quantities via inhalation or absorption through skin; VX is more potent than sarin, another nerve agent with a similar mechanism of action. On such exposure, these agents severely disrupt the body's signaling between the nervous and muscular systems, leading to a prolonged neuromuscular blockade, flaccid paralysis of all the muscles in the body including the diaphragm, and death by asphyxiation.[9] The danger of VX, in particular, lies in direct exposure to the chemical agent persisting where it was dispersed, and not through its evaporating and being distributed as a vapor; it is not considered a vapor hazard due to its relative non-volatility. VX is considered an area denial weapon due to these physical and biochemical characteristics.[10] As a chemical weapon, it is categorized as a weapon of mass destruction by the United Nations and is banned by the Chemical Weapons Convention of 1993,[11] where production and stockpiling of VX exceeding 100 grams (3.53 oz) per year is outlawed. The only exception is for "research, medical or pharmaceutical purposes outside a single small-scale facility in aggregate quantities not exceeding 10 kg (22 lb) per year per facility".[12]
Diethyl 2,4,6-trimethyl-3,4-dihydropyridine-3,5-dicarboxylate
3-[(5E)-5-methyl-4-oxo-2-hydroxy-5-octenyl]glutarimide
5,6,7,8-Tetramethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
5-Amino-2,6-dimethyl-6-hydroxy-4-(2-methylbutyryl)-3-methoxy-2,4-cyclohexadien-1-one
3-Deoxy-3-methylaminoxylose-beta-D-Furanose-form-Me glycoside, 5-benzyl|3-Deoxy-3-methylaminoxylose-Me glycoside, 5-benzyl
1,1-Dimethyl-2-[1-(hydroxymethyl)-2-hydroxyethyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
Atenolol acid
A monocarboxylic acid that is phenylacetic acid substituted by a 2-hydroxy-3-(propan-2-ylamino)propoxy group at position 4. It is a metabolite of the drug atenolol. CONFIDENCE standard compound; INTERNAL_ID 2025 CONFIDENCE standard compound; EAWAG_UCHEM_ID 697 EAWAG_UCHEM_ID 697; CONFIDENCE standard compound
Voglibose
A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BF - Alpha glucosidase inhibitors C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent D007004 - Hypoglycemic Agents > D065089 - Glycoside Hydrolase Inhibitors C471 - Enzyme Inhibitor > C2846 - Glucosidase Inhibitor D004791 - Enzyme Inhibitors Voglibose is a derivative of valiolamine, which can inhibit α-glucosidase very well and can act on hyperglycemia.
butyl prop-2-enoate,2-methylprop-2-enoic acid,prop-2-enenitrile
Boronic acid, B-[3-fluoro-4-[3-(1-pyrrolidinyl)propoxy]phenyl]
2-Isopropyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
3,5-DIMETHYL-1H-PYRROLE-2,4-DICARBOXYLICACID4-TERT-BUTYLESTER2-ETHYLESTER
2-tert-Butyl 4-ethyl 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate
vx.
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors D009676 - Noxae > D011042 - Poisons > D002619 - Chemical Warfare Agents D004791 - Enzyme Inhibitors
1-BENZYL-4-(4-FLUOROPHENYL)-1,2,3,6-TETRAHYDROPYRIDINE
Ethyl 2,4-dimethyl-5-(ethoxycarbonyl)-3-pyrrolepropionate
[2-HYDROXY-2-(4-METHOXY-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
7-(1-Pyrrolidinylmethyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one
butyl prop-2-enoate,ethenyl acetate,prop-2-enenitrile
(3S,4S)-TERT-BUTYL4-(FURAN-3-YL)-3-HYDROXYPIPERIDINE-1-CARBOXYLATE
3-(5-Methyl-1H-imidazol-4-yl)-1-(1-methyl-1H-indol-3-yl)-1-propanone
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-phenyl-
3-Hydroxy-4-hydroxymethyl-1-(4-oxo-4,4A,5,7A-tetrahydro-3H-pyrrolo[3,2-D]pyrimidin-7-ylmethyl)-pyrrolidinium
N-tert-butyl-1-phenyl-4-pyrazolo[3,4-d]pyrimidinamine
3-(1-hydroxy-5,5-dimethyl-4-phenyl-2H-imidazol-2-yl)pyridine
4-(Methoxymethyl)-6-methyl-2-(2-methylanilino)-3-pyridinecarbonitrile
(E,2E)-N-(1,2,4-Triazol-4-yl)-2-(1,3,3-trimethylindol-2-ylidene)ethanimine
N-[(E)-1-Cyclopropylethylideneamino]-2-pyrrol-1-ylbenzamide
(S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one
2-methoxy-N-[(1-methyl-2-benzimidazolyl)methyl]aniline
2-(3-Methylpentan-2-ylamino)-6-methylsulanylbenzoic acid
N-Hydroxy-3,4-(methylenedioxy)amphetamine, TMS derivative
2-Butoxy-3-pyridinecarboxylic acid trimethylsilyl ester
LYSERGAMIDE
An ergoline alkaloid comprising ergoline lacking hydrogens at positions 9 and 10 and also having a methyl group attached to the piperidine nitrogen.
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate
6-hydroxy-1-(5-hydroxyhex-1-en-1-yl)-8-methyl-1h,5h,6h,8ah-[1,3]oxazolo[3,4-a]pyridin-3-one
(4s,7r)-6-methyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),2,9,12,14-pentaene-4-carboximidic acid
6,7-dihydroxy-1,1-dimethyl-n-(2'-glyceryl)-1,2,3,4-tetrahydroisoquinoline
{"Ingredient_id": "HBIN012059","Ingredient_name": "6,7-dihydroxy-1,1-dimethyl-n-(2'-glyceryl)-1,2,3,4-tetrahydroisoquinoline","Alias": "NA","Ingredient_formula": "C14H21NO4","Ingredient_Smile": "CC1(C2=CC(=C(C=C2CCN1C(CO)CO)O)O)C","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "5854","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
