3-(5-Methyl-1H-imidazol-4-yl)-1-(1-methyl-1H-indol-3-yl)-1-propanone (BioDeep_00000845837)
代谢物信息卡片
化学式: C16H17N3O (267.1371552)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(N=CN1)CCC(=O)C2=CN(C3=CC=CC=C32)C
InChI: InChI=1S/C16H17N3O/c1-11-14(18-10-17-11)7-8-16(20)13-9-19(2)15-6-4-3-5-12(13)15/h3-6,9-10H,7-8H2,1-2H3,(H,17,18)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Abrar Ashoor, Jacob C Nordman, Daniel Veltri, Keun-Hang Susan Yang, Yaroslav Shuba, Lina Al Kury, Bassem Sadek, Frank C Howarth, Amarda Shehu, Nadine Kabbani, Murat Oz. Menthol inhibits 5-HT3 receptor-mediated currents.
The Journal of pharmacology and experimental therapeutics.
2013 Nov; 347(2):398-409. doi:
10.1124/jpet.113.203976. [PMID: 23965380] - Katharina Heimes, Florian Hauk, Eugen J Verspohl. Mode of action of peppermint oil and (-)-menthol with respect to 5-HT3 receptor subtypes: binding studies, cation uptake by receptor channels and contraction of isolated rat ileum.
Phytotherapy research : PTR.
2011 May; 25(5):702-8. doi:
10.1002/ptr.3316. [PMID: 21077259] - C Nothdurfter, S Tanasic, G Rammes, R Rupprecht. Modulation of ligand-gated ion channels as a novel pharmacological principle.
Pharmacopsychiatry.
2011 May; 44 Suppl 1(?):S27-34. doi:
10.1055/s-0031-1271704. [PMID: 21544743] - Keun-Hang Yang, Sehamuddin Galadari, Dmytro Isaev, Georg Petroianu, Toni S Shippenberg, Murat Oz. The nonpsychoactive cannabinoid cannabidiol inhibits 5-hydroxytryptamine3A receptor-mediated currents in Xenopus laevis oocytes.
The Journal of pharmacology and experimental therapeutics.
2010 May; 333(2):547-54. doi:
10.1124/jpet.109.162594. [PMID: 20160007] - Delia Kurzwelly, Martin Barann, Arevat Kostanian, Sandra Combrink, Heinz Bönisch, Manfred Göthert, Michael Brüss. Pharmacological and electrophysiological properties of the naturally occurring Pro391Arg variant of the human 5-HT3A receptor.
Pharmacogenetics.
2004 Mar; 14(3):165-72. doi:
10.1097/00008571-200403000-00004. [PMID: 15167704] - S Mochizuki, T Watanabe, A Miyake, M Saito, K Furuichi. Cloning, expression, and characterization of ferret 5-HT(3) receptor subunit.
European journal of pharmacology.
2000 Jul; 399(2-3):97-106. doi:
10.1016/s0014-2999(00)00371-x. [PMID: 10884508] - F Chen, A J Lawrence. 5-HT transporter sites and 5-HT1A and 5-HT3 receptors in Fawn-Hooded rats: a quantitative autoradiography study.
Alcoholism, clinical and experimental research.
2000 Jul; 24(7):1093-102. doi:
10.1111/j.1530-0277.2000.tb04655.x. [PMID: 10924015] - M Brüss, G J Molderings, H Bönisch, M Göthert. Pharmacological differences and similarities between the native mouse 5-HT3 receptor in N1E-115 cells and a cloned short splice variant of the mouse 5-HT3 receptor expressed in HEK 293 cells.
Naunyn-Schmiedeberg's archives of pharmacology.
1999 Sep; 360(3):225-33. doi:
10.1007/s002109900088. [PMID: 10543422] - A P Tairi, R Hovius, H Pick, H Blasey, A Bernard, A Surprenant, K Lundström, H Vogel. Ligand binding to the serotonin 5HT3 receptor studied with a novel fluorescent ligand.
Biochemistry.
1998 Nov; 37(45):15850-64. doi:
10.1021/bi981812z. [PMID: 9843391] - C H Wetzel, B Hermann, C Behl, E Pestel, G Rammes, W Zieglgänsberger, F Holsboer, R Rupprecht. Functional antagonism of gonadal steroids at the 5-hydroxytryptamine type 3 receptor.
Molecular endocrinology (Baltimore, Md.).
1998 Sep; 12(9):1441-51. doi:
10.1210/mend.12.9.0163. [PMID: 9731711]