Voglibosa (BioDeep_00000176123)
human metabolite blood metabolite
代谢物信息卡片
化学式: C10H21NO7 (267.13179560000003)
中文名称:
谱图信息:
最多检出来源 Mus musculus(blood) 85.71%
分子结构信息
SMILES: C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO
InChI: InChI=1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2
描述信息
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- M Tominaga, M Kimura, M Igarashi, H Eguchi, K Igarashi, T Abe, K Sugiyama, H Manaka, H Sasaki. Slight but significant improvement of insulin resistance of Wistar fatty rats by treatment with a disaccharidase inhibitor, AO-128.
The Tohoku journal of experimental medicine.
1997 Mar; 181(3):353-60. doi:
10.1620/tjem.181.353. [PMID: 9163850] - R Hayaishi, M Wada, E Imano, T Kanda. [Occurrence of ileus after voglibose treatment in an elderly diabetic patient with gait disturbance caused by cerebral hemorrhage].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics.
1996 Aug; 33(8):607-12. doi:
10.3143/geriatrics.33.607. [PMID: 8921700] - K Shinozaki, M Suzuki, M Ikebuchi, J Hirose, Y Hara, Y Harano. Improvement of insulin sensitivity and dyslipidemia with a new alpha-glucosidase inhibitor, voglibose, in nondiabetic hyperinsulinemic subjects.
Metabolism: clinical and experimental.
1996 Jun; 45(6):731-7. doi:
10.1016/s0026-0495(96)90139-0. [PMID: 8637448] - Y Goto, K Yamada, T Ohyama, T Matsuo, H Odaka, H Ikeda. An alpha-glucosidase inhibitor, AO-128, retards carbohydrate absorption in rats and humans.
Diabetes research and clinical practice.
1995 May; 28(2):81-7. doi:
10.1016/0168-8227(95)01065-l. [PMID: 7587923] - T Nakamura, K Takebe, K Kudoh, A Terada, Y Tandoh, Y Arai, N Yamada, M Ishii, H Kikuchi. Effect of an alpha-glucosidase inhibitor on intestinal fermentation and faecal lipids in diabetic patients.
The Journal of international medical research.
1993 Sep; 21(5):257-67. doi:
10.1177/030006059302100504. [PMID: 8112483] - N Fukase, H Takahashi, H Manaka, M Igarashi, K Yamatani, M Daimon, K Sugiyama, M Tominaga, H Sasaki. Differences in glucagon-like peptide-1 and GIP responses following sucrose ingestion.
Diabetes research and clinical practice.
1992 Mar; 15(3):187-95. doi:
10.1016/0168-8227(92)90024-l. [PMID: 1576919] - H Odaka, A Shino, H Ikeda, T Matsuo. Antiobesity and antidiabetic actions of a new potent disaccharidase inhibitor in genetically obese-diabetic mice, KKA(y).
Journal of nutritional science and vitaminology.
1992 Feb; 38(1):27-37. doi:
10.3177/jnsv.38.27. [PMID: 1629784] - T Matsuo, H Odaka, H Ikeda. Effect of an intestinal disaccharidase inhibitor (AO-128) on obesity and diabetes.
The American journal of clinical nutrition.
1992 01; 55(1 Suppl):314S-317S. doi:
10.1093/ajcn/55.1.314s. [PMID: 1728846] - Y Inui, S Kawata, Y Matsuzawa, K Tokunaga, S Fujioka, S Tamura, T Kobatake, Y Keno, H Odaka, T Matsuo. Inhibitory effect of a new alpha-glucosidase inhibitor on fatty liver in Zucker fatty rats.
Journal of hepatology.
1990 Jan; 10(1):62-8. doi:
10.1016/0168-8278(90)90074-2. [PMID: 2407772] - T Kobatake, Y Matsuzawa, K Tokunaga, S Fujioka, T Kawamoto, Y Keno, Y Inui, H Odaka, T Matsuo, S Tarui. Metabolic improvements associated with a reduction of abdominal visceral fat caused by a new alpha-glucosidase inhibitor, AO-128, in Zucker fatty rats.
International journal of obesity.
1989; 13(2):147-54. doi:
NULL. [PMID: 2663746] - Y Inui, S Kawata, T Kobatake, S Tamura, S Fujioka, K Tokunaga, Y Minami, Y Matsuzawa, S Tarui. [The effect of an alpha-glucosidase inhibitor on fatty liver in obesity].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.
1987 Aug; 84(8):1639-44. doi:
". [PMID: 3320414]