Exact Mass: 233.1346
Exact Mass Matches: 233.1346
Found 164 metabolites which its exact mass value is equals to given mass value 233.1346,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Methylphenidate
Methylphenidate is only found in individuals that have used or taken this drug. It is a central nervous system stimulant used most commonly in the treatment of attention-deficit disorders in children and for narcolepsy. Its mechanisms appear to be similar to those of dextroamphetamine. [PubChem]Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal system and the cerebral cortex and causes increased sympathomimetic activity in the central nervous system. Alteration of serotonergic pathways via changes in dopamine transport may result. N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
Normeperidine
Pethidine (INN) or meperidine hydrochloride (USAN) (commonly referred to as Demerol in the US but also referred to as: isonipecaine; lidol; pethanol; piridosal; Algil; Alodan; Centralgin; Dispadol; Dolantin; Mialgin (in Indonesia); Petidin Dolargan (in Poland); Dolestine; Dolosal; Dolsin; Mefedina) is a fast-acting opioid analgesic drug. Pethidine is quickly hydrolysed in the liver to pethidinic acid and is also demethylated to norpethidine, which has half the analgesic activity of pethidine but a longer elimination half-life (8-12 hours); accumulating with regular administration, or in renal failure. Norpethidine is toxic and has convulsant and hallucinogenic effects. The toxic effects mediated by the metabolites cannot be countered with opioid receptor antagonists such as naloxone or naltrexone and are probably primarily due to norpethidines anticholinergic activity probably due to its structural similarity to atropine though its pharmacology has not been thoroughly explored. The neurotoxicity of pethidines metabolites is a unique feature of pethidine compared to other opioids. Pethidines metabolites are further conjugated with glucuronic acid and excreted into the urine. D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors D004791 - Enzyme Inhibitors
Thalictroidine
Thalictroidine is found in coffee and coffee products. Thalictroidine is an alkaloid from the rhizomes of Caulophyllum thalictroides (blue cohosh Alkaloid from the rhizomes of Caulophyllum thalictroides (blue cohosh). Thalictroidine is found in coffee and coffee products.
Seryllysine
Seryllysine is a dipeptide composed of serine and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.
Lysylserine
Lysylserine is a dipeptide composed of lysine and serine. It is an incomplete breakdown product of protein digestion or protein catabolism. Dipeptides are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Some dipeptides are known to have physiological or cell-signalling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.
Hydroxypropionylcarnitine
Hydroxypropionylcarnitine is an acylcarnitine. More specifically, it is an hydroxypropionoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. Hydroxypropionylcarnitine is therefore classified as a short chain AC. As a short-chain acylcarnitine hydroxypropionylcarnitine is a member of the most abundant group of carnitines in the body, comprising more than 50\\% of all acylcarnitines quantified in tissues and biofluids (PMID: 31920980). Some short-chain carnitines have been studied as supplements or treatments for a number of diseases, including neurological disorders and inborn errors of metabolism. It is also decreased in the urine of individuals with obesity (PMID: 26910390) and systolic heart failure (PMID: 26010610). Hydroxypropionylcarnitine can also be found incerebrospinal fluid. Carnitine acetyltransferase (CrAT, EC:2.3.1.7) is responsible for the synthesis of all short-chain and short branched-chain acylcarnitines (PMID: 23485643). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews]. A human metabolite taken as a putative food compound of mammalian origin [HMDB]
Dexmethylphenidate
Dexmethylphenidate is only found in individuals that have used or taken this drug. It is the dextrorotary form of methylphenidate. It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD). Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal system and the cerebral cortex and causes increased sympathomimetic activity in the central nervous system.Methylphenidate is a catecholamine reuptake inhibitor that indirectly increases catecholaminergic neurotransmission by inhibiting the dopamine transporter (DAT) and norepinephrine transporter (NET), which are responsible for clearing catecholamines from the synapse, particularly in the striatum and meso-limbic system. N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide
D000975 - Antioxidants > D016166 - Free Radical Scavengers D020011 - Protective Agents > D000975 - Antioxidants
4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]butanoic acid
D002491 - Central Nervous System Agents > D018697 - Nootropic Agents
metolachlor morpholinone
A member of the class of morpholines that is morpholin-3-one substituted by a 2-ethyl-6-methylphenyl group at position 4 and a methyl group at position 5. It is a metabolite of metolachlor. CONFIDENCE standard compound; EAWAG_UCHEM_ID 67
1,2-Epoxy-2-methyl-4-(N-methyltyraminyl)-3-butene|4-(2-N-methyltyraminyl)-(Z)-1,2-epoxy-2-methylbut-3-ene
Me glycoside,N-Ac,4-mesyl-beta-D-Pyranose-3-Amino-3,6-dideoxygalactose
N-[2-(4-Methoxyphenyl)ethyl]-3-methylbut-2-enamide
Et glycoside,N-Ac-alpha-D-Pyranose-2-Amino-2,3-dideoxy-ribo-hexopyranose
Metolachlor-Morpholinone
CONFIDENCE standard compound; INTERNAL_ID 2059
Ritalin
N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
Dexmethylphenidate
N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
(4aS,11bS)-9-methoxy-2,3,4,4a,5,6,7,11b-octahydrobenzo[1,2]cyclohepta[4,6-c][1,4]oxazine
1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid t-butyl ester
(S)-METHYL 2-((TERT-BUTOXYCARBONYL)AMINO)-3-METHOXYPROPANOATE
5-TERT-BUTYL-2-(2-FLUORO-PHENYL)-2H-PYRAZOL-3-YLAMINE
3-Methyl-1-(phenylmethyl)-3-pyrrolidinecarboxylic acid methyl ester
methyl (2S)-4-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate
7-tert-butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
1,3-Benzodioxole-5-methanamine,N-cyclohexyl-, hydrochloride (1:1)
1-[(3-methylphenyl)methyl]piperidine-4-carboxylic acid
6-[2-(dimethylamino)ethoxy]-3,4-dihydro-2H-naphthalen-1-one
2,2,5,5-tetramethyl-4-phenyl-3-imidazoline-3-oxide-1-oxyl
(R)-ETHYL 2-((TERT-BUTOXYCARBONYL)AMINO)-3-HYDROXYPROPANOATE
2-Nitro-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene
Piperoxan
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
3-(TERT-BUTYL)-1-(3-FLUOROPHENYL)-1H-PYRAZOL-5-AMINE
(2S)-2-(N-tert-Butoxycarbonyl)amino-3-hydroxy-3-methylbutanoic acid
1-(4-hydroxy-3-piperidin-1-ylmethyl-phenyl)-ethanone
(4-(1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL)METHANAMINE
(1R,5S,9r)-7-benzyl-3-oxa-7-azabicyclo[3.3.1]nonan-9-ol
1-(1-PYRROLIDINYLCARBONYLMETHYL)PIPERAZINEHYDROCHLORIDE
Benzoic acid, 3-(1-aminocyclopropyl)-, 1,1-dimethylethyl ester
methyl (3R,4R)-1-benzyl-4-methylpyrrolidine-3-carboxylate
2-((TERT-BUTOXYCARBONYL)AMINO)-3-HYDROXY-3-METHYLBUTANOIC ACID
hexahydro-3-(3-methoxyphenyl)-1-methyl-2H-azepin-2-one
ethyl 3-hydroxy-4,4-dimethoxypiperidine-1-carboxylate
6-AMINO-5-(TERT-BUTYL)-3,3-DIMETHYLBENZOFURAN-2(3H)-ONE
(Z)-but-2-enedioic acid,2-(dimethylamino)-2-methylpropan-1-ol
6-(tert-Butyl)-2,2-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one
(3S,4R)-rel-1-Boc-3-fluoro-4-(hydroxyMethyl)piperidine
Methyl N-{[(2-methyl-2-propanyl)oxy]carbonyl}homoserinate
1-(3,4-DIMETHYLPHENYLAMINO)CYCLOPENTANECARBOXYLICACID
1-(3,5-DIMETHYLPHENYLAMINO)CYCLOPENTANECARBOXYLICACID
Hopantenic acid
D002491 - Central Nervous System Agents > D018697 - Nootropic Agents C26170 - Protective Agent > C1509 - Neuroprotective Agent
Daytrana
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
2-(2,6-Diaminohexanoylamino)-3-hydroxypropanoic acid
2-[[(2S)-2,6-diaminohexanoyl]amino]oxypropanoic acid
O-(hydroxypropionyl)carnitine
An O-acylcarnitine in which the acyl group specified is hydroxypropionyl.
O-hydroxypropionyl-L-carnitine
An O-acyl-L-carnitine in which the acyl group specified is hydroxypropionyl in which the position of the hydroxy group is unspecified..
Fluoroethylnormemantine (hydrochloride)
Fluoroethylnormemantine hydrochloride, a derivative of Memantine, is an antagonist of the N-methyl-D-aspartate (NMDA) receptor. [18F]-Fluoroethylnormemantine hydrochloride can be used as a positron emission tomography (PET) tracer. Fluoroethylnormemantine hydrochloride exhibits anti-amnesic, neuroprotective, antidepressant-like and fear-attenuating effects[1][2][3].
