Chemical Formula: C14H19NO2
Chemical Formula C14H19NO2
Found 89 metabolite its formula value is C14H19NO2
Methylphenidate
Methylphenidate is only found in individuals that have used or taken this drug. It is a central nervous system stimulant used most commonly in the treatment of attention-deficit disorders in children and for narcolepsy. Its mechanisms appear to be similar to those of dextroamphetamine. [PubChem]Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal system and the cerebral cortex and causes increased sympathomimetic activity in the central nervous system. Alteration of serotonergic pathways via changes in dopamine transport may result. N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
Normeperidine
Pethidine (INN) or meperidine hydrochloride (USAN) (commonly referred to as Demerol in the US but also referred to as: isonipecaine; lidol; pethanol; piridosal; Algil; Alodan; Centralgin; Dispadol; Dolantin; Mialgin (in Indonesia); Petidin Dolargan (in Poland); Dolestine; Dolosal; Dolsin; Mefedina) is a fast-acting opioid analgesic drug. Pethidine is quickly hydrolysed in the liver to pethidinic acid and is also demethylated to norpethidine, which has half the analgesic activity of pethidine but a longer elimination half-life (8-12 hours); accumulating with regular administration, or in renal failure. Norpethidine is toxic and has convulsant and hallucinogenic effects. The toxic effects mediated by the metabolites cannot be countered with opioid receptor antagonists such as naloxone or naltrexone and are probably primarily due to norpethidines anticholinergic activity probably due to its structural similarity to atropine though its pharmacology has not been thoroughly explored. The neurotoxicity of pethidines metabolites is a unique feature of pethidine compared to other opioids. Pethidines metabolites are further conjugated with glucuronic acid and excreted into the urine. D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors D004791 - Enzyme Inhibitors
Thalictroidine
Thalictroidine is found in coffee and coffee products. Thalictroidine is an alkaloid from the rhizomes of Caulophyllum thalictroides (blue cohosh Alkaloid from the rhizomes of Caulophyllum thalictroides (blue cohosh). Thalictroidine is found in coffee and coffee products.
Dexmethylphenidate
Dexmethylphenidate is only found in individuals that have used or taken this drug. It is the dextrorotary form of methylphenidate. It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD). Methylphenidate blocks dopamine uptake in central adrenergic neurons by blocking dopamine transport or carrier proteins. Methylphenidate acts at the brain stem arousal system and the cerebral cortex and causes increased sympathomimetic activity in the central nervous system.Methylphenidate is a catecholamine reuptake inhibitor that indirectly increases catecholaminergic neurotransmission by inhibiting the dopamine transporter (DAT) and norepinephrine transporter (NET), which are responsible for clearing catecholamines from the synapse, particularly in the striatum and meso-limbic system. N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
metolachlor morpholinone
A member of the class of morpholines that is morpholin-3-one substituted by a 2-ethyl-6-methylphenyl group at position 4 and a methyl group at position 5. It is a metabolite of metolachlor. CONFIDENCE standard compound; EAWAG_UCHEM_ID 67
1,2-Epoxy-2-methyl-4-(N-methyltyraminyl)-3-butene|4-(2-N-methyltyraminyl)-(Z)-1,2-epoxy-2-methylbut-3-ene
N-[2-(4-Methoxyphenyl)ethyl]-3-methylbut-2-enamide
Metolachlor-Morpholinone
CONFIDENCE standard compound; INTERNAL_ID 2059
Ritalin
N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
Dexmethylphenidate
N - Nervous system > N06 - Psychoanaleptics > N06B - Psychostimulants, agents used for adhd and nootropics > N06BA - Centrally acting sympathomimetics D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators
(4aS,11bS)-9-methoxy-2,3,4,4a,5,6,7,11b-octahydrobenzo[1,2]cyclohepta[4,6-c][1,4]oxazine
1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid t-butyl ester
3-Methyl-1-(phenylmethyl)-3-pyrrolidinecarboxylic acid methyl ester
7-tert-butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
1,3-Benzodioxole-5-methanamine,N-cyclohexyl-, hydrochloride (1:1)
1-[(3-methylphenyl)methyl]piperidine-4-carboxylic acid
6-[2-(dimethylamino)ethoxy]-3,4-dihydro-2H-naphthalen-1-one
2-Nitro-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene
Piperoxan
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C72900 - Adrenergic Antagonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
1-(4-hydroxy-3-piperidin-1-ylmethyl-phenyl)-ethanone
(1R,5S,9r)-7-benzyl-3-oxa-7-azabicyclo[3.3.1]nonan-9-ol
Benzoic acid, 3-(1-aminocyclopropyl)-, 1,1-dimethylethyl ester
methyl (3R,4R)-1-benzyl-4-methylpyrrolidine-3-carboxylate
hexahydro-3-(3-methoxyphenyl)-1-methyl-2H-azepin-2-one
6-AMINO-5-(TERT-BUTYL)-3,3-DIMETHYLBENZOFURAN-2(3H)-ONE
6-(tert-Butyl)-2,2-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one
1-(3,4-DIMETHYLPHENYLAMINO)CYCLOPENTANECARBOXYLICACID
1-(3,5-DIMETHYLPHENYLAMINO)CYCLOPENTANECARBOXYLICACID
Daytrana
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators