Exact Mass: 197.0736232
Exact Mass Matches: 197.0736232
Found 500 metabolites which its exact mass value is equals to given mass value 197.0736232,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
L-Dopa
L-dopa is an optically active form of dopa having L-configuration. Used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinsons disease It has a role as a prodrug, a hapten, a neurotoxin, an antiparkinson drug, a dopaminergic agent, an antidyskinesia agent, an allelochemical, a plant growth retardant, a human metabolite, a mouse metabolite and a plant metabolite. It is a dopa, a L-tyrosine derivative and a non-proteinogenic L-alpha-amino acid. It is a conjugate acid of a L-dopa(1-). It is an enantiomer of a D-dopa. It is a tautomer of a L-dopa zwitterion. Levodopa is a prodrug of dopamine that is administered to patients with Parkinsons due to its ability to cross the blood-brain barrier. Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after it has crossed the blood-brain barrier. Once past the blood-brain barrier, levodopa is metabolized to dopamine and supplements the low endogenous levels of dopamine to treat symptoms of Parkinsons. The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product called Sinemet that was approved on May 2, 1975. 3,4-Dihydroxy-L-phenylalanine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). Levodopa is an Aromatic Amino Acid. Levodopa is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brain, levodopa is decarboxylated to dopamine and stimulates the dopaminergic receptors, thereby compensating for the depleted supply of endogenous dopamine seen in Parkinsons disease. To assure that adequate concentrations of levodopa reach the central nervous system, it is administered with carbidopa, a decarboxylase inhibitor that does not cross the blood-brain barrier, thereby diminishing the decarboxylation and inactivation of levodopa in peripheral tissues and increasing the delivery of dopamine to the CNS. L-Dopa is used for the treatment of Parkinsonian disorders and Dopa-Responsive Dystonia and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. Peripheral tissue conversion may be the mechanism of the adverse effects of levodopa. It is standard clinical practice to co-administer a peripheral DOPA decarboxylase inhibitor - carbidopa or benserazide - and often a catechol-O-methyl transferase (COMT) inhibitor, to prevent synthesis of dopamine in peripheral tissue.The naturally occurring form of dihydroxyphenylalanine and the immediate precursor of dopamine. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to dopamine. It is used for the treatment of parkinsonian disorders and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. [PubChem]L-Dopa is the naturally occurring form of dihydroxyphenylalanine and the immediate precursor of dopamine. Unlike dopamine itself, L-Dopa can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to dopamine. In particular, it is metabolized to dopamine by aromatic L-amino acid decarboxylase. Pyridoxal phosphate (vitamin B6) is a required cofactor for this decarboxylation, and may be administered along with levodopa, usually as pyridoxine. The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside ... L-DOPA, also known as levodopa or 3,4-dihydroxyphenylalanine is an alpha amino acid. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). L-DOPA is found naturally in both animals and plants. It is made via biosynthesis from the amino acid L-tyrosine by the enzyme tyrosine hydroxylase.. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), which are collectively known as catecholamines. The Swedish scientist Arvid Carlsson first showed in the 1950s that administering L-DOPA to animals with drug-induced (reserpine) Parkinsonian symptoms caused a reduction in the intensity of the animals symptoms. Unlike dopamine itself, L-DOPA can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to dopamine. In particular, it is metabolized to dopamine by aromatic L-amino acid decarboxylase. Pyridoxal phosphate (vitamin B6) is a required cofactor for this decarboxylation, and may be administered along with levodopa, usually as pyridoxine. As a result, L-DOPA is a drug that is now used for the treatment of Parkinsonian disorders and DOPA-Responsive Dystonia. It is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. It is standard clinical practice in treating Parkinsonism to co-administer a peripheral DOPA decarboxylase inhibitor - carbidopa or benserazide - and often a catechol-O-methyl transferase (COMT) inhibitor, to prevent synthesis of dopamine in peripheral tissue. Side effects of L-DOPA treatment may include: hypertension, arrhythmias, nausea, gastrointestinal bleeding, disturbed respiration, hair loss, disorientation and confusion. L-DOPA can act as an L-tyrosine mimetic and be incorporated into proteins by mammalian cells in place of L-tyrosine, generating protease-resistant and aggregate-prone proteins in vitro and may contribute to neurotoxicity with chronic L-DOPA administration. L-phenylalanine, L-tyrosine, and L-DOPA are all precursors to the biological pigment melanin. The enzyme tyrosinase catalyzes the oxidation of L-DOPA to the reactive intermediate dopaquinone, which reacts further, eventually leading to melanin oligomers. An optically active form of dopa having L-configuration. Used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinsons disease DOPA. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=59-92-7 (retrieved 2024-07-01) (CAS RN: 59-92-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). DL-Dopa is a beta-hydroxylated derivative of phenylalanine. DL-Dopa is a beta-hydroxylated derivative of phenylalanine.
Aniline Yellow
D004396 - Coloring Agents CONFIDENCE standard compound; INTERNAL_ID 1313; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8954; ORIGINAL_PRECURSOR_SCAN_NO 8952 CONFIDENCE standard compound; INTERNAL_ID 1313; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8961; ORIGINAL_PRECURSOR_SCAN_NO 8959 CONFIDENCE standard compound; INTERNAL_ID 1313; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8978; ORIGINAL_PRECURSOR_SCAN_NO 8977 CONFIDENCE standard compound; INTERNAL_ID 1313; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8974; ORIGINAL_PRECURSOR_SCAN_NO 8972 CONFIDENCE standard compound; INTERNAL_ID 1313; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8989; ORIGINAL_PRECURSOR_SCAN_NO 8988 CONFIDENCE standard compound; INTERNAL_ID 1313; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8997; ORIGINAL_PRECURSOR_SCAN_NO 8995 CONFIDENCE standard compound; INTERNAL_ID 2428 CONFIDENCE standard compound; INTERNAL_ID 8113 CONFIDENCE standard compound; INTERNAL_ID 4141
N-Acetylhistidine
N-Acetyl-L-histidine or N-Acetylhistidine, belongs to the class of organic compounds known as N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. N-Acetylhistidine can also be classified as an alpha amino acid or a derivatized alpha amino acid. Technically, N-Acetylhistidine is a biologically available N-terminal capped form of the proteinogenic alpha amino acid L-histidine. N-acetyl amino acids can be produced either via direct synthesis of specific N-acetyltransferases or via the proteolytic degradation of N-acetylated proteins by specific hydrolases. N-terminal acetylation of proteins is a widespread and highly conserved process in eukaryotes that is involved in protection and stability of proteins (PMID: 16465618). About 85\\% of all human proteins and 68\\% of all yeast proteins are acetylated at their N-terminus (PMID: 21750686). Several proteins from prokaryotes and archaea are also modified by N-terminal acetylation. The majority of eukaryotic N-terminal-acetylation reactions occur through N-acetyltransferase enzymes or NAT’s (PMID: 30054468). These enzymes consist of three main oligomeric complexes NatA, NatB, and NatC, which are composed of at least a unique catalytic subunit and one unique ribosomal anchor. The substrate specificities of different NAT enzymes are mainly determined by the identities of the first two N-terminal residues of the target protein. The human NatA complex co-translationally acetylates N-termini that bear a small amino acid (A, S, T, C, and occasionally V and G) (PMID: 30054468). NatA also exists in a monomeric state and can post-translationally acetylate acidic N-termini residues (D-, E-). NatB and NatC acetylate N-terminal methionine with further specificity determined by the identity of the second amino acid. N-acetylated amino acids, such as N-acetylhistidine can be released by an N-acylpeptide hydrolase from peptides generated by proteolytic degradation (PMID: 16465618). In addition to the NAT enzymes and protein-based acetylation, N-acetylation of free histidine can also occur. In particular, N-Acetylhistidine can be biosynthesized from L-histidine and acetyl-CoA by the enzyme histidine N-acetyltransferase (EC 2.3.1.33). Many N-acetylamino acids are classified as uremic toxins if present in high abundance in the serum or plasma (PMID: 26317986; PMID: 20613759). Uremic toxins are a diverse group of endogenously produced molecules that, if not properly cleared or eliminated by the kidneys, can cause kidney damage, cardiovascular disease and neurological deficits (PMID: 18287557). Constituent of the tissues of various fish and amphibian subspecies N-Acetylhistidine is found in fishes. KEIO_ID A073
N-Hydroxy-L-tyrosine
Biosynthetic intermediate of dhurrin in Sorghum bicolor (sorghum). N-Hydroxy-L-tyrosine is found in many foods, some of which are allspice, asparagus, lemon thyme, and sparkleberry. N-Hydroxy-L-tyrosine is found in cereals and cereal products. Biosynthetic intermediate of dhurrin in Sorghum bicolor (sorghum).
Methyl5-(but-3-en-1-yl)amino-1,3,4-oxadiazole-2-carboxylate
3-Amino-1-methyl-5H-pyrido[4,3-b]indole
3-Amino-1-methyl-5H-pyrido[4,3-b]indole is isolated from protein pyrolysates contg. tryptophan. Mutagenic potential food contaminant. Isolated from protein pyrolysates contg. tryptophan. Mutagenic potential food contaminant. D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens
HC Red 3
CONFIDENCE standard compound; INTERNAL_ID 517; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1613; ORIGINAL_PRECURSOR_SCAN_NO 1611 CONFIDENCE standard compound; INTERNAL_ID 517; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1614; ORIGINAL_PRECURSOR_SCAN_NO 1611 CONFIDENCE standard compound; INTERNAL_ID 517; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1605; ORIGINAL_PRECURSOR_SCAN_NO 1604 CONFIDENCE standard compound; INTERNAL_ID 517; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1619; ORIGINAL_PRECURSOR_SCAN_NO 1617 CONFIDENCE standard compound; INTERNAL_ID 517; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1629; ORIGINAL_PRECURSOR_SCAN_NO 1626 CONFIDENCE standard compound; INTERNAL_ID 517; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1597; ORIGINAL_PRECURSOR_SCAN_NO 1592
1-Hydroxy-3-methyl-9H-carbazole
1-Hydroxy-3-methyl-9H-carbazole is found in herbs and spices. 1-Hydroxy-3-methyl-9H-carbazole is an alkaloid from the stem bark of Murraya koenigii (curryleaf tree). Alkaloid from the stem bark of Murraya koenigii (curryleaf tree). 1-Hydroxy-3-methyl-9H-carbazole is found in herbs and spices.
2-Hydroxy-3-methyl-9H-carbazole
2-Hydroxy-3-methyl-9H-carbazole is found in herbs and spices. 2-Hydroxy-3-methyl-9H-carbazole is an alkaloid from the roots of Murraya koenigii (curryleaf tree). Alkaloid from the roots of Murraya koenigii (curryleaf tree). 2-Hydroxy-3-methyl-9H-carbazole is found in herbs and spices.
2-Hydroxy-3-(3,4-dihydroxyphenyl)propanamide
2-Hydroxy-3-(3,4-dihydroxyphenyl)propanamide is found in herbs and spices. 2-Hydroxy-3-(3,4-dihydroxyphenyl)propanamide is isolated from rhizomes of sage plant. Isolated from rhizomes of sage plant. 2-Hydroxy-3-(3,4-dihydroxyphenyl)propanamide is found in herbs and spices.
DL-Dopa
DL-DOPA, also known as (+-)-DOPA or (R,S)-DOPA or DL-3,4-dihydroxyphenylalanine is an alpha amino acid. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). DL-DOPA also belongs to the class of organic compounds known as tyrosines and derivatives. Tyrosines and derivatives are compounds containing tyrosine or a derivative thereof resulting from reaction of tyrosine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. DL-DOPA is a racemic mixture of both D-DOPA and L-DOPA. D-DOPA is similar to L-DOPA (levodopa), but with opposite chirality. Levo- and dextro- rotation refer to a molecules ability to rotate planes of polarized light in one or the other direction. Whereas L-DOPA is moderately effective in the treatment of Parkinsons disease (PD) by stimulating the production of dopamine in the brain, D-DOPA was at one time thought to be biologically inactive. However, it has recently been found that D-DOPA can be converted to L-DOPA and then to dopamine via the human enzyme known as D-amino acid oxidase and that racemic mixtures of DL-DOPA can be effective in treating Parkinsonism (PMID: 17924443; PMID: 3129126; PMID: 17042912). The biological production or biosynthesis of D-DOPA is thought to occur through bacterial conversion of tyrosine. L-DOPA is found naturally in both animals and plants. It is made via biosynthesis from the amino acid L-tyrosine by the enzyme tyrosine hydroxylase. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), which are collectively known as catecholamines. The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. [HMDB] DL-Dopa is a beta-hydroxylated derivative of phenylalanine. DL-Dopa is a beta-hydroxylated derivative of phenylalanine.
N-(4-hydroxyphenyl)ethoxycarbothioamide
N-(4-hydroxyphenyl)ethoxycarbothioamide is found in fats and oils. N-(4-hydroxyphenyl)ethoxycarbothioamide is a constituent of Moringa oleifera (horseradish tree). Constituent of Moringa oleifera (horseradish tree). N-(4-hydroxyphenyl)ethoxycarbothioamide is found in fats and oils, herbs and spices, and green vegetables.
Beclamide
C10H12ClNO (197.06073719999998)
C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics
Stizolamine
Stizolamine is a member of the class of compounds known as pyrazines. Pyrazines are compounds containing a pyrazine ring, which is a six-member aromatic heterocycle, that consists of two nitrogen atoms (at positions 1 and 4) and four carbon atoms. Stizolamine is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Stizolamine can be found in broad bean and peanut, which makes stizolamine a potential biomarker for the consumption of these food products.
2-Chloro-N-(2,6-dimethylphenyl)acetamide
C10H12ClNO (197.06073719999998)
excavatine C|methyl 2-(1,2-dihydroxyethyl)pyridine-4-carboxylate
Levodopa
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.054 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.053 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.052
DL-Dopa
DL-Dopa is a beta-hydroxylated derivative of phenylalanine. DL-Dopa is a beta-hydroxylated derivative of phenylalanine.
Beclamide
C10H12ClNO (197.06073719999998)
C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics
N,N-Acetylhistidine
MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; KBOJOGQFRVVWBH-ZETCQYMHSA-N_STSL_0239_N-Acetylhistidine_0062fmol_190403_S2_LC02MS02_071; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
3,4-Dihydroxy-phenylalanine (L-DOPA); AIF; CE0; MS2Dec
3,4-Dihydroxy-phenylalanine (L-DOPA); AIF; CE10; MS2Dec
3,4-Dihydroxy-phenylalanine (L-DOPA); AIF; CE30; MS2Dec
Thiourea, N-(2-hydroxyethyl)-N-4-pyridinyl- (9CI)
C8H11N3OS (197.06227959999998)
Thiourea, N-(2-hydroxyethyl)-N-3-pyridinyl- (9CI)
C8H11N3OS (197.06227959999998)
N-(4-Chlorobenzyl)-N-ethylethanamine
C11H16ClN (197.09712059999998)
4-(2-Methoxyphenyl)-3-thiosemicarbazide
C8H11N3OS (197.06227959999998)
3-methylhistamine dihydrochloride
3-Methylhistamine dihydrochloride is a degradation product of histamine. 3-Methylhistamine dihydrochloride, a methylated product of histamine, is associated with immune response and shows upregulation in the vaccinated mice[1][2].
3-METHYLPYRROLE-2,4-DICARBOXYLIC ACID DIMETHYL ESTER
Acetamide,2-chloro-N-(2,3-dimethylphenyl)-
C10H12ClNO (197.06073719999998)
1H-Benzimidazole-2-methanamine,5,6-difluoro-N-methyl-(9CI)
4-tert-butyl-1-fluoro-2-nitrobenzene
C10H12FNO2 (197.08520240000001)
1-isopropyl-4-(S-methylsulfonimidoyl)benzene
C10H15NOS (197.08742999999998)
2-Chloro-N-(2,4-dimethylphenyl)acetamide
C10H12ClNO (197.06073719999998)
N-[2-(4-chlorophenyl)ethyl]acetamide
C10H12ClNO (197.06073719999998)
Hydrazinecarbothioamide,N-(4-methoxyphenyl)-
C8H11N3OS (197.06227959999998)
2-chloro-n,n-dimethyl-2-phenylacetamide
C10H12ClNO (197.06073719999998)
(E)-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ylidene)acetonitrile
1-(6-chloropyridin-2-yl)piperazine
C9H12ClN3 (197.07197019999998)
Propanedinitrile,2-[[4-(dimethylamino)phenyl]methylene]-
3-(4,6-DIAMINO-2,2-DIMETHYL-2H-[1,3,5]TRIAZIN-1-YL)-BENZOIC ACID HYDROCHLORIDE
C11H16ClN (197.09712059999998)
2-chloro-N-(4-methylphenyl)propanamide
C10H12ClNO (197.06073719999998)
METHYL 3-AMINO-2-HYDROXY-5-METHOXYBENZENECARBOXYLATE
Thiourea, N-ethyl-N-(3-hydroxy-2-pyridinyl)- (9CI)
C8H11N3OS (197.06227959999998)
(1R,2R)-2-amino-1,2-dihydronaphthalen-1-ol,hydrochloride
C10H12ClNO (197.06073719999998)
2-acetyl-3-amino-5-t-butylthiophene
C10H15NOS (197.08742999999998)
1-(2-Chloro-4-pyridinyl)piperazine
C9H12ClN3 (197.07197019999998)
(6-BROMO-PYRIDIN-2-YL)-PHENYL-METHANONE
C10H12ClNO (197.06073719999998)
4-Chloro-2-methyl-6-pyrrolidin-1-yl-pyrimidine
C9H12ClN3 (197.07197019999998)
3-AMINO-4-(4-FLUORO-PHENYL)-BUTYRIC ACID
C10H12FNO2 (197.08520240000001)
1-ETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE
C11H16ClN (197.09712059999998)
1H-Benzimidazole,1-methyl-2-(1H-pyrrol-2-yl)-(9CI)
ethyl 2-amino-4-fluoro-3-methylbenzoate
C10H12FNO2 (197.08520240000001)
Methyl 2-[5-(3-Phenoxyphenyl)-2H-tetrazol-2-yl]acetate
C9H12ClN3 (197.07197019999998)
Ethyl 4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate
1-(4-Chloro-2-pyridinyl)piperazine
C9H12ClN3 (197.07197019999998)
2-oxo-6-(2-pyridinyl)-1,2-dihydro-3-pyridinecarbonitrile
N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-2-AMINE HYDROCHLORIDE
C11H16ClN (197.09712059999998)
(1,2,6,7,-Tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile
ETHYL 4-HYDROXY-1-METHYL-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXYLATE
2,3-DIHYDRO-3,3-DIMETHYL-1,2-BENZISOTHIAZOLE 1,1-DIOXIDE
2-(1H-BENZOIMIDAZOL-2-YL)-ETHYLAMINE HCL
C9H12ClN3 (197.07197019999998)
1H-Benzimidazole,2-(1-methyl-1H-pyrrol-2-yl)-(9CI)
2-(2-CHLORO-PHENYL)-ACETIMIDIC ACID ETHYL ESTER
C10H12ClNO (197.06073719999998)
ALANINE, N-(2-FLUOROPHENYL)-2-METHYL-
C10H12FNO2 (197.08520240000001)
2-(2-Methyl-1H-imidazol-1-yl)ethanamine dihydrochloride
n-benzyl-2-chloro-n-methylacetamide
C10H12ClNO (197.06073719999998)
4-Chloro-N-cyclopentyl-2-pyrimidinamine
C9H12ClN3 (197.07197019999998)
4-chloro-6-piperidin-1-ylpyrimidine
C9H12ClN3 (197.07197019999998)
1-(3-Chloro-2-pyridinyl)piperazine
C9H12ClN3 (197.07197019999998)
(R)-(-)-α-Methylhistamine dihydrochloride
(R)-(-)-α-Methylhistamine dihydrochloride is a potent, selective and brain-penetrant agonist of H3 histamine receptor, with a Kd of 50.3 nM[1][2]. (R)-(-)-α-Methylhistamine dihydrochloride can enhance memory retention, attenuates memory impairment in rats[3][4][5].
piperidin-4-yl(thiophen-2-yl)methanol
C10H15NOS (197.08742999999998)
3-(2-amino-4-methyl-6-oxo-pyrimidin-1-yl)propanoic acid
Hydrazinecarbothioamide,N-(3-methoxyphenyl)-
C8H11N3OS (197.06227959999998)
(1-Methyl-1H-indazol-6-yl)Methanamine HCL
C9H12ClN3 (197.07197019999998)
5-Pyrimidinecarbonitrile, 2-(4-hydroxyphenyl)- (9CI)
6-(2,5-dimethylpyrrol-1-yl)pyridine-3-carbonitrile
1-(6-chloropyridin-3-yl)piperazine
C9H12ClN3 (197.07197019999998)
3-[4-(Methylsulfanyl)phenoxy]-1-propanamine
C10H15NOS (197.08742999999998)
(1R)-1-(1H-benzimidazol-2-yl)ethanamine,hydrochloride
C9H12ClN3 (197.07197019999998)
3-chloro-6-piperidin-1-ylpyridazine
C9H12ClN3 (197.07197019999998)
3-Chloropropyl-N-benzylmethylamine
C11H16ClN (197.09712059999998)
(3R)-4-Amino-3-(4-fluorophenyl)butanoic acid
C10H12FNO2 (197.08520240000001)
Methyl 3-amino-4-hydroxy-5-methoxybenzenecarboxylate
2,3-Difluoro-4-propoxybenzonitrile
C10H9F2NO (197.06521679999997)
2-Cyclopropyl-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione
2,3-Dimethyl-2H-indazol-6-amine hydrochloride
C9H12ClN3 (197.07197019999998)
6-METHOXY-3,4-DIHYDROISOQUINOLINE HYDROCHLORIDE
C10H12ClNO (197.06073719999998)
[2-(dimethylamino)-4-methoxypyrimidin-5-yl]boronic acid
(3-CHLORO-3-PHENYL-PROPYL)-DIMETHYL-AMINE HYDROCHLORIDE
C11H16ClN (197.09712059999998)
2-CHLORO-N-(1-PHENYL-ETHYL)-ACETAMIDE
C10H12ClNO (197.06073719999998)
Acetamide,2-chloro-N-ethyl-N-phenyl-
C10H12ClNO (197.06073719999998)
[(2,5-Dimethyl-furan-3-carbonyl)-amino]-acetic acid
Pyrimido[1,2-a]benzimidazole, 2,4-dimethyl- (6CI,7CI,8CI,9CI)
9,9-Dimethyl-1-oxa-7-azaspiro[4.4]nonane-2,6,8-trione
3-(M-TOLYL)PYRROLIDINE HYDROCHLORIDE
C11H16ClN (197.09712059999998)
Pyrimidine,2-chloro-4-(1-piperidinyl)-
C9H12ClN3 (197.07197019999998)
L-Carnitine hydrochloride
C7H16ClNO3 (197.08186560000001)
L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3].
Cyclopropanamine, 1-(3-ethylphenyl)-, hydrochloride (1:1)
C11H16ClN (197.09712059999998)
1H-Pyrrole-2-aceticacid, 3-(methoxycarbonyl)-, methyl ester
2-Pyridinecarboxylic acid, 6-fluoro-, 1,1-dimethylethyl ester
C10H12FNO2 (197.08520240000001)
ETHYL 4-HYDROXY-2-METHYL-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXYLATE
3-Pyridinecarboxylic acid, 6-fluoro-, 1,1-dimethylethyl ester
C10H12FNO2 (197.08520240000001)
N-[(1R)-1-(4-Chlorophenyl)ethyl]acetamide
C10H12ClNO (197.06073719999998)
4-methoxycarbonyl-3,5-dimethyl-1H-pyrrole-2-carboxylic acid
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane carboxamide
C10H9F2NO (197.06521679999997)
2-chloro-N-[(2-methylphenyl)methyl]acetamide
C10H12ClNO (197.06073719999998)
5-Butyl-1H-benzotriazole sodium salt
C10H12N3Na (197.09288719999998)
3-(4-Methylphenyl)Pyrrolidine Hydrochloride
C11H16ClN (197.09712059999998)
3-Benzylpyrrolidine hydrochloride (1:1)
C11H16ClN (197.09712059999998)
(R)-3-AMINO-4-(2-BROMO-PHENYL)-BUTYRICACIDHCL
C10H12FNO2 (197.08520240000001)
2-chloro-n-(2,5-dimethylphenyl)acetamide
C10H12ClNO (197.06073719999998)
2-(4-acetyl-5-methyl-2-oxo-1,3-dihydropyrrol-3-yl)acetic acid
Ethyl 3-amino-5-fluoro-4-methylbenzoate
C10H12FNO2 (197.08520240000001)
(4-thiophen-2-yloxan-4-yl)methanamine
C10H15NOS (197.08742999999998)
2-Chloro-N-(1-phenylethyl)acetamide
C10H12ClNO (197.06073719999998)
6-Chloro-N-cyclopentylpyridazin-3-amine
C9H12ClN3 (197.07197019999998)
2-(1H-Benzimidazol-1-yl)ethylamine hydrochloride
C9H12ClN3 (197.07197019999998)
2-[5-(Pyrrolidin-1-yl)-2H-tetrazol-2-yl]ethanoic acid, 2-(Carboxymethyl)-5-(pyrrolidin-1-yl)-2H-tetrazole
2-(4-CHLORO-PHENYL)-ACETIMIDIC ACID ETHYL ESTER
C10H12ClNO (197.06073719999998)
N-(methoxymethyl)-1-(trifluoromethyl)cyclopropane-1-carboxamide
4-ETHYL-1,2,3,4-TETRAHYDROISOQUINOLINEHYDROCHLORIDE
C11H16ClN (197.09712059999998)
(S)-2-AMINO-3-(4-FLUOROPHENYL)-2-METHYLPROPANOIC ACID
C10H12FNO2 (197.08520240000001)
1-Methylhistamine dihydrochloride
1-Methylhistamine dihydrochloride is a histamine metabolite[1].
2-(aminomethyl)-3-(2-fluorophenyl)propanoic acid
C10H12FNO2 (197.08520240000001)
2-(aminomethyl)-3-(4-fluorophenyl)propanoic acid
C10H12FNO2 (197.08520240000001)
(R)-(+)-N-ALLYL-ALPHA-METHYLBENZYLAMINE
C11H16ClN (197.09712059999998)
(R)-3-AMINO-4-(3-CHLORO-PHENYL)-BUTYRICACIDHCL
C10H12FNO2 (197.08520240000001)
2,4-DICHLORO-6-METHYLBENZENESULPHONAMIDE
C10H12FNO2 (197.08520240000001)
2-chloro-n-(3,5-dimethylphenyl)acetamide
C10H12ClNO (197.06073719999998)
2-chloro-n-(4-ethylphenyl)acetamide
C10H12ClNO (197.06073719999998)
(R)-(-)-α-Methylhistamine dihydrobromide,(R)-(-)-α-Methyl-1H-imidazole-4-ethanaminedihydrobromide
3,7-dimethyl-1-(trideuteriomethyl)purine-2,6-dione
C8H7D3N4O2 (197.09920353400003)
1,3-dimethyl-7-(trideuteriomethyl)purine-2,6-dione
C8H7D3N4O2 (197.09920353400003)
TCN 238
TCN238 is an orally bioavailable mGlu4 receptor positive allosteric modulator (PAM) with an EC50 of 1 μM[1].
3-(2-Methylphenyl)Pyrrolidine Hydrochloride
C11H16ClN (197.09712059999998)
1-(2-AMINO-5-CHLORO-4-ETHYLPHENYL)-ETHANONE
C10H12ClNO (197.06073719999998)
Mefenidil
C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent
5-Chloro-2-(piperazin-1-yl)pyridine
C9H12ClN3 (197.07197019999998)
Thiourea, (6-ethoxy-3-pyridinyl)- (9CI)
C8H11N3OS (197.06227959999998)
5-Pyrimidinecarboxylic acid, 1,4-dihydro-2-[(1-methylethyl)amino]-4-oxo- (9CI)
4-Methylhistamine dihydrochloride
4-Methylhistamine (dihydrochloride) is the potent agonist of histamine 4 receptor (H4R). 4-Methylhistamine (dihydrochloride) has the potential for the research of immune-related diseases such as cancer and autoimmune disorders[1].
2-(4-METHYL-1H-IMIDAZOL-2-YL)-ETHYLAMINE DIHYDROCHLORIDE
3-amino-1-chloro-4-phenylbutan-2-one
C10H12ClNO (197.06073719999998)
3-Fluoro-alpha-methyl-L-phenylalanine
C10H12FNO2 (197.08520240000001)
Methanone, (4-aminophenyl)cyclopropyl-, hydrochloride
C10H12ClNO (197.06073719999998)
6-Fluoro-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester
6-chloro-2,2-dimethyl-3,4-dihydro-2H-benzo[b][1,4]oxazine
C10H12ClNO (197.06073719999998)
N6-Ethyl-4,5,6,7-tetrahydro-2,6-benzothiazolediaMine
1-(4-methyl-1H-imidazol-2-yl)ethanamine(SALTDATA: 1.95HCl 0.5H2O 0.15NaCl)
(R)-2-phenylpiperidine hydrochloride
C11H16ClN (197.09712059999998)
[(1,2-Dimethyl-1H-imidazol-5-yl)methyl]amine dihydrochloride
3-[(2-Methoxyethyl)(methyl)amino]propanoic acid hydrochloride
C7H16ClNO3 (197.08186560000001)
Methyl 4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
2-Amino-2-(4-fluorophenyl)butanoic acid
C10H12FNO2 (197.08520240000001)
1H-Benzimidazole,2-(4,5-dihydro-3-pyridinyl)-(9CI)
2-(2-Chloroethyl)-1-methylpiperidine hydrochloride
2-(carboxymethyl)-1,4-dimethylpyrrole-3-carboxylic acid
2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid
Carnitine chloride
C7H16ClNO3 (197.08186560000001)
Carnitine chloride. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=461-05-2 (retrieved 2024-07-09) (CAS RN: 461-05-2). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0). (±)-Carnitine chloride exists in two isomers, known as D and L. L-carnitine plays an essential role in the β-oxidation of fatty acids and also shows antioxidant, and anti-inflammatory activities. (±)-Carnitine chloride exists in two isomers, known as D and L. L-carnitine plays an essential role in the β-oxidation of fatty acids and also shows antioxidant, and anti-inflammatory activities.
1-(5-chloropyridin-3-yl)piperazine
C9H12ClN3 (197.07197019999998)
4-((2-Chloroethyl)(methyl)amino)benzaldehyde
C10H12ClNO (197.06073719999998)
(1-AMINOMETHYL-CYCLOPENTYL)-CARBAMICACIDTERT-BUTYLESTER
(TETRAHYDROFURAN-2-YLMETHYL)(3-THIENYLMETHYL)AMINE
C10H15NOS (197.08742999999998)
2-CHLORO-N-(2-ETHYL-PHENYL)-ACETAMIDE
C10H12ClNO (197.06073719999998)
2-amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid methyl ester
1H-Pyrrole-2,4-dicarboxylicacid, 3-methyl-, 4-ethyl ester
1H-Benzimidazole-2-ethanamine,hydrochloride (1:2)
C9H12ClN3 (197.07197019999998)
4-CHLORO-6-METHYL-2-(1-PYRROLIDINYL)PYRIMIDINE
C9H12ClN3 (197.07197019999998)
1H-Pyrrole-2,4-dicarboxylicacid, 3-methyl-, 2-ethyl ester
1,3-Dimethyl-6-Methylamino-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxaldehyde
(R)-1-(1H-Benzimidazol-2-yl)ethylamine Hydrochloride
C9H12ClN3 (197.07197019999998)
2-Amino-1,2,3,4-tetrahydrocyclopenta[b]indole-7-carbonitrile
Xanthopterin Hydrate
Xanthopterin hydrate, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm[2]. Xanthopterin hydrate(XPT) causes renal growth and hypertrophy in rat[1]. Xanthopterin hydrate inhibits RNA synthesis[4]. Xanthopterin hydrate, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm[2]. Xanthopterin hydrate(XPT) causes renal growth and hypertrophy in rat[1]. Xanthopterin hydrate inhibits RNA synthesis[4].
4,4-Dimethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
C11H16ClN (197.09712059999998)
3-methyl-7,8-dihydroquinolin-5(6H)-one hydrochloride
C10H12ClNO (197.06073719999998)
(2R)-2-amino-3-(2,4-dihydroxyphenyl)propanoic acid
(2S)-2-azaniumyl-3-(3,4-dihydroxyphenyl)propanoate
7-deoxyloganetate
A monocarboxylic acid anion that is the conjugate base of 7-deoxyloganetic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.
cis-5,6-Dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate
(S)-2-Amino-3-(3-hydroxy-4-oxo-4H-pyridin-1-yl)propanoate
2-(Hydroxy-methoxy-phosphinoyl)oxyethylaminoformamidine
2-furaldehyde N-ethylthiosemicarbazone
C8H11N3OS (197.06227959999998)
(6S)-3,3-dimethyl-5,6-dihydro-4H-pyridine-2,6-dicarboxylate
N-Acetyl-L-histidine
A histidine derivative that is L-histidine having an acetyl substituent on the alpha-nitrogen.
Methyl 5-(but-3-en-1-yl)amino-1,3,4-oxadiazole-2-carboxylate
L-dopa zwitterion
An amino acid zwitterion obtained from the transfer of a proton from the carboxy group to the amino group of L-dopa. Major microspecies at pH 7.3.
Dopa
A hydroxyphenylalanine carrying hydroxy substituents at positions 3 and 4 of the benzene ring.
Trp-P-2
D009676 - Noxae > D002273 - Carcinogens D009676 - Noxae > D009153 - Mutagens
D-dopa zwitterion
An amino acid zwitterion obtained from the transfer of a proton from the carboxy group to the amino group of D-dopa. Major microspecies at pH 7.3.
1-Chloro-2-dimethylamino-1-phenylpropane
C11H16ClN (197.09712059999998)
