2-(4,5-Dihydro-1H-imidazol-2-yl)quinoline (BioDeep_00000910977)
代谢物信息卡片
2-(4,5-Dihydro-1H-imidazol-2-yl)quinoline
化学式: C12H11N3 (197.0952926)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CN=C(N1)C2=NC3=CC=CC=C3C=C2
InChI: InChI=1S/C12H11N3/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12/h1-6H,7-8H2,(H,13,14)
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - K-C Lin, L-R Yeh, L-J Chen, Y-J Wen, K-C Cheng, J-T Cheng. Plasma glucose-lowering action of allantoin is induced by activation of imidazoline I-2 receptors in streptozotocin-induced diabetic rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
2012 Jan; 44(1):41-6. doi:
10.1055/s-0031-1295439. [PMID: 22147657] - Chin-Hong Chang, Hung-Tsung Wu, Kai-Chun Cheng, Hung-Jung Lin, Juei-Tang Cheng. Increase of beta-endorphin secretion by agmatine is induced by activation of imidazoline I(2A) receptors in adrenal gland of rats.
Neuroscience letters.
2010 Jan; 468(3):297-9. doi:
10.1016/j.neulet.2009.11.018. [PMID: 19913596] - Chin-Hong Chang, Chiung-Wen Tsao, Su-Ying Huang, Juei-Tang Cheng. Activation of imidazoline I(2B) receptors by guanidine to increase glucose uptake in skeletal muscle of rats.
Neuroscience letters.
2009 Dec; 467(2):147-9. doi:
10.1016/j.neulet.2009.10.026. [PMID: 19822195] - Chin-Hui Su, I-Min Liu, Hsien-Hui Chung, Juei-Tang Cheng. Activation of I2-imidazoline receptors by agmatine improved insulin sensitivity through two mechanisms in type-2 diabetic rats.
Neuroscience letters.
2009 Jul; 457(3):125-8. doi:
10.1016/j.neulet.2009.03.093. [PMID: 19429177] - Wen Ching Ko, I-Min Liu, Hsien-Hui Chung, Juei-Tang Cheng. Activation of I(2)-imidazoline receptors may ameliorate insulin resistance in fructose-rich chow-fed rats.
Neuroscience letters.
2008 Dec; 448(1):90-3. doi:
10.1016/j.neulet.2008.10.002. [PMID: 18926881] - S-L Hwang, I-M Liu, T-F Tzeng, J-T Cheng. Activation of imidazoline receptors in adrenal gland to lower plasma glucose in streptozotocin-induced diabetic rats.
Diabetologia.
2005 Apr; 48(4):767-75. doi:
10.1007/s00125-005-1698-2. [PMID: 15756537] - David P Finn, Alan L Hudson, Hiroshi Kinoshita, Toni L Coventry, David S Jessop, David J Nutt, Michael S Harbuz. Imidazoline2 (I2) receptor- and alpha2-adrenoceptor-mediated modulation of hypothalamic-pituitary-adrenal axis activity in control and acute restraint stressed rats.
Journal of psychopharmacology (Oxford, England).
2004 Mar; 18(1):47-53. doi:
10.1177/0269881104040231. [PMID: 15107184] - David P Finn, Octavi Martí, Michael S Harbuz, Astrid Vallès, Xavier Belda, Cristina Márquez, David S Jessop, Margaret D Lalies, Antonio Armario, David J Nutt, Alan L Hudson. Behavioral, neuroendocrine and neurochemical effects of the imidazoline I2 receptor selective ligand BU224 in naive rats and rats exposed to the stress of the forced swim test.
Psychopharmacology.
2003 May; 167(2):195-202. doi:
10.1007/s00213-003-1392-3. [PMID: 12652345] - Dirk Gründemann, Ann-Cathrin Koschker, Christine Haag, Cornelius Honold, Tim Zimmermann, Edgar Schömig. Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells.
British journal of pharmacology.
2002 Nov; 137(6):910-8. doi:
10.1038/sj.bjp.0704926. [PMID: 12411423] - D P Finn, M D Lalies, M S Harbuz, D S Jessop, A L Hudson, D J Nutt. Imidazoline(2) (I(2)) binding site- and alpha(2)-adrenoceptor-mediated modulation of central noradrenergic and HPA axis function in control rats and chronically stressed rats with adjuvant-induced arthritis.
Neuropharmacology.
2002 Jun; 42(7):958-65. doi:
10.1016/s0028-3908(02)00046-1. [PMID: 12069906]