Exact Mass: 157.9838
Exact Mass Matches: 157.9838
Found 391 metabolites which its exact mass value is equals to given mass value 157.9838,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Dihydroorotic acid
4,5-Dihydroorotic acid, also known as dihydroorotate or hydroorotate is a pyrimidinemonocarboxylic acid that results from the base-catalysed cyclisation of N-alpha-carbethoxyasparagine. It is classified as a secondary amide, a monocarboxylic acid, a pyrimidinemonocarboxylic acid and a N-acylurea. 4,5-Dihydroorotic acid is a derivative of orotic acid which serves as an intermediate in pyrimidine biosynthesis. 4,5-Dihydroorotic acid exists in all living species, ranging from bacteria to plants to humans. 4,5-Dihydroorotic acid is synthesized by the enzyme known as Dihydroorotase (EC 3.5.2.3) which converts carbamoyl aspartic acid into 4,5-dihydroorotic acid as part of the de novo pyrimidine biosynthesis pathway (PMID: 13163076). 4,5-Dihydroorotic acid is also a substrate for the enzyme known as dihydroorotate dehydrogenase (DHODH). In mammalian species, DHODH catalyzes the fourth step in the de novo pyrimidine biosynthesis pathway, which involves the ubiquinone-mediated oxidation of dihydroorotate to orotate and the reduction of flavin mononucleotide (FMN) to dihydroflavin mononucleotide (FMNH2). Inhibition of DHODH activity with teriflunomide (an immunomodulatory drug) or expression with RNA interference results in reduced ROS generation and consequent apoptosis of transformed skin and prostate epithelial cells. Mutations in the DHOD gene have been shown to cause Miller syndrome, also known as Genee-Wiedemann syndrome, Wildervanck-Smith syndrome or post-axial acrofacial dystosis (PMID: 19915526). 4,5-Dihydroorotic acid is a substrate of the enzyme orotate reductase [EC 1.3.1.14], which is part of the pyrimidine metabolism pathway. (KEGG) Dihydroorotate is oxidized by Dihydroorotate dehydrogenases (DHODs) to orotate. These dehydrogenases use their FMN (flavin mononucleotide) prosthetic group to abstract a hydride equivalent from C6 to deprotonate C5 [HMDB] L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme[1].
2-Maleylacetate
This compound belongs to the family of Medium-chain Keto Acids and Derivatives. These are keto acids with a 6 to 12 carbon atoms long side chain
2-Methylene-4-oxopentanedioic acid
2-Oxo-4-methylenepentanedioic acid is found in nuts. 2-Oxo-4-methylenepentanedioic acid is found in peanut (Arachis hypogaea).
Ibotenic acid
D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018690 - Excitatory Amino Acid Agonists D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites. Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.
Mustard gas
D011042 - Poisons > D002619 - Chemical Warfare Agents > D009151 - Mustard Gas D009676 - Noxae > D011042 - Poisons > D002619 - Chemical Warfare Agents D003879 - Dermatologic Agents
Dimethyl tetrasulfide
Constituent of various Allium subspecies and Lentinus species Dimethyl tetrasulfide is found in many foods, some of which are mushrooms, soft-necked garlic, garden onion, and shiitake. Dimethyl tetrasulfide is found in garden onion. Dimethyl tetrasulfide is a constituent of various Allium species and Lentinus sp.
Zymonic acid
Zymonic acid is used as a flavour constituent for confectionery and tobacc
L-Dihydroorotic acid
L-Dihydroorotic acid, also known as (S)-4,5-dihydroorotate or dihydro-L-orotate, belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof. 4,5-Dihydroorotic acid is a derivative of orotic acid which serves as an intermediate in pyrimidine biosynthesis. L-Dihydroorotic acid is a drug. L-Dihydroorotic acid exists in all living species, ranging from bacteria to humans. Within humans, L-dihydroorotic acid participates in a number of enzymatic reactions. In particular, L-dihydroorotic acid can be biosynthesized from ureidosuccinic acid; which is catalyzed by the enzyme cad protein. In addition, L-dihydroorotic acid and quinone can be converted into orotic acid through the action of the enzyme dihydroorotate dehydrogenase (quinone), mitochondrial. In humans, L-dihydroorotic acid is involved in the metabolic disorder called the beta-ureidopropionase deficiency pathway. Outside of the human body, L-dihydroorotic acid has been detected, but not quantified in several different foods, such as black chokeberries, vanilla, sweet basils, soy beans, and broad beans. L-Dihydroorotic acid is an intermediate in the metabolism of Pyrimidine. It is a substrate for Dihydroorotate dehydrogenase (mitochondrial). [HMDB]. L-Dihydroorotic acid is found in many foods, some of which are lemon balm, eggplant, arrowhead, and european cranberry. L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme[1].
Dimethyldithiophosphate
Dimethyldithiophosphate, also known as O,O-dimethyldithiophosphate, O,O-dimethyl phosphorodithioate, copper (+1) salt or O,O-dimethyldithiophosphoric acid, is classified as a member of the phosphorodithioic acid O,O-diesters. Phosphorodithioic acid O,O-diesters are organooxygen compounds that contain a phosphorodithioic acid, which is O,O-disubstituted by an organyl group. Dimethyldithiophosphate is considered to be slightly soluble (in water) and acidic. (ChemoSummarizer)
Calcium acetate
It is used in foods as a firming agent, acidity regulator, sequestrant, stabiliser and thickener, and nutrient supplement (Ca source). It is used as an acidifier/preservative in bread, and in some gelling mixtures. Calcium acetate is a food additive, mainly in candy products.; Calclacite is a name for calcium acetate chloride pentahydrate, which is treated as mineral species but possess anthropogenic origin.; Patients with advanced renal insufficiency (creatinine clearance less than 30 ml/min) exhibit phosphate retention and some degree of hyperphosphatemia. The retention of phosphate plays a pivotal role in causing secondary hyperparathyroidism associated with osteodystrophy, and soft-tissue calcification. The mechanism by which phosphate retention leads to hyperparathyroidism is not clearly delineated. Therapeutic efforts directed toward the control of hyperphosphatemia include reduction in the dietary intake of phosphate, inhibition of absorption of phosphate in the intestine with phosphate binders, and removal of phosphate from the body by more efficient methods of dialysis. The rate of removal of phosphate by dietary manipulation or by dialysis is insufficient. Dialysis patients absorb 40\\% to 80\\% of dietary phosphorus. Therefore, the fraction of dietary phosphate absorbed from the diet needs to be reduced by using phosphate binders in most renal failure patients on maintenance dialysis. Calcium acetate when taken with meals combines with dietary phosphate to form insoluble calcium phosphate which is excreted in the feces. Maintenance of serum phosphorus below 6.0 mg/dl is generally considered as a clinically acceptable outcome of treatment with phosphate binders. Calcium acetate is highly soluble at neutral pH, making the calcium readily available for binding to phosphate in the proximal small intestine. It is used in foods as a firming agent, acidity regulator, sequestrant, stabiliser and thickener, and nutrient supplement (Ca source). It is used as an acidifier/preservative in bread, and in some gelling mixtures V - Various > V03 - All other therapeutic products > V03A - All other therapeutic products > V03AE - Drugs for treatment of hyperkalemia and hyperphosphatemia D064449 - Sequestering Agents > D002614 - Chelating Agents
BENZENESULFONIC ACID
CONFIDENCE standard compound; INTERNAL_ID 1369; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1375; ORIGINAL_PRECURSOR_SCAN_NO 1374 CONFIDENCE standard compound; INTERNAL_ID 1369; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1393; ORIGINAL_PRECURSOR_SCAN_NO 1392 CONFIDENCE standard compound; INTERNAL_ID 1369; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1384; ORIGINAL_PRECURSOR_SCAN_NO 1383 CONFIDENCE standard compound; INTERNAL_ID 1369; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1391; ORIGINAL_PRECURSOR_SCAN_NO 1390 CONFIDENCE standard compound; INTERNAL_ID 1369; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1394; ORIGINAL_PRECURSOR_SCAN_NO 1393 CONFIDENCE standard compound; INTERNAL_ID 1369; DATASET 20200303_ENTACT_RP_MIX504; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1412; ORIGINAL_PRECURSOR_SCAN_NO 1411 CONFIDENCE standard compound; INTERNAL_ID 2388 CONFIDENCE standard compound; INTERNAL_ID 8695
L-Dihydroorotic acid
The (S)-enantiomer of dihydroorotic acid that is an intermediate in the metabolism of pyridine. L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme[1].
Dihydroorotate
L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme[1].
1H-Imidazole-4,5-dicarboxylicacid,2,3-dihydro-(9CI)
2-CYCLOPROPYLAMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
Urea,(5-methyl-1,3,4-thiadiazol-2-yl)- (6CI,8CI,9CI)
5-METHYL-2-THIOXO-DIHYDROPYRIMIDINE-4,6(1H,5H)-DIONE
(s)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid
1,2,5-Thiadiazole-3-carboxylicacid,4-methyl-,methylester(9CI)
1H-1,2,3-Triazole-4-carboxamide,5-(methylthio)-(9CI)
4-Methyl-1,2,3-thiadiazole-5-carboxylic acid hydrazide
1H-Pyrazole-4-carbonyl chloride, 1,3-dimethyl- (9CI)
3-Isothiazolecarboxylicacid,4-amino-,methylester(9CI)
1H-Imidazole-4-carboxylicacid,5-mercapto-,hydrazide(9CI)
5-(chloromethyl)-3-cyclopropyl-1,2,4-oxadiazole(SALTDATA: FREE)
4-AMINO-3-MERCAPTO-6-METHYL-4H-[1,2,4]TRIAZIN-5-ONE
(S)-4-(4-ETHYL-2-OXOOXAZOLIDIN-3-YL)BENZOICACIDMETHYLESTER
1,2,4-Thiadiazole-5-carboxylicacid,3-methyl-,methylester
1H-Imidazole-4-carboxylicacid,5-mercapto-,methylester(9CI)
2,3-dihydro-3-methyl-2-thioxo-1H-imidazole-4-carboxylic acid
2-methylene-4-oxopentanedioic acid
Found in peanut (Arachis hypogaea)
1-(2-CHLOROBENZYL)-6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLICACID
2-(methylamino)-1,3-thiazole-4-carboxylic acid(SALTDATA: 1.25H2O 0.15 NaCl)
1,2,3-Thiadiazole-5-carboxylicacid,4-methyl-,methylester(9CI)
5-Isothiazolecarboxamide,2,3-dihydro-2-methyl-3-oxo-(9CI)
Calcium acetate
V - Various > V03 - All other therapeutic products > V03A - All other therapeutic products > V03AE - Drugs for treatment of hyperkalemia and hyperphosphatemia D064449 - Sequestering Agents > D002614 - Chelating Agents
2-Oxohexanedioate
COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
(S)-3-Hydroxy-5-oxo-2,5-dihydrofuran-2beta-acetic acid
Mustard gas
D011042 - Poisons > D002619 - Chemical Warfare Agents > D009151 - Mustard Gas D009676 - Noxae > D011042 - Poisons > D002619 - Chemical Warfare Agents D003879 - Dermatologic Agents
Ibotenic acid
D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018690 - Excitatory Amino Acid Agonists D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites. Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.
N-formimidoyl-L-aspartate(2-)
A dicarboxylic acid anion resuting from removal of a proton from both carboxy groups of N-formimidoyl-L-aspartic acid.
2-oxoadipate(2-)
Dianion of 2-oxoadipic acid arising from deprotonation of both carboxylic acid groups.
3-oxoadipate(2-)
A dicarboxylic acid dianion resuting from deprotonation of both carboxy groups of 3-oxoadipic acid.
