Mustard gas (BioDeep_00001867966)
Main id: BioDeep_00000012658
Volatile Flavor Compounds
代谢物信息卡片
Mustard gas
化学式: C4H8Cl2S (157.9723748)
中文名称: 芥子气
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CCl)SCCCl
InChI: InChI=1S/C4H8Cl2S/c5-1-3-7-4-2-6/h1-4H2
描述信息
D011042 - Poisons > D002619 - Chemical Warfare Agents > D009151 - Mustard Gas
D009676 - Noxae > D011042 - Poisons > D002619 - Chemical Warfare Agents
D003879 - Dermatologic Agents
同义名列表
3 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:25434
- KEGG: C19164
- PubChem: 10461
- ChEMBL: CHEMBL455341
- MeSH: Mustard Gas
- CAS: 505-60-2
- PubChem: 124489836
- KNApSAcK: 25434
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Chuchu Gong, Zhengyan Gu, Xinkang Zhang, Qingqiang Xu, Guanchao Mao, Zhipeng Pei, Wenqi Meng, Jinfeng Cen, Jihao Liu, Xiaowen He, Mingxue Sun, Kai Xiao. HMSCs exosome-derived miR-199a-5p attenuates sulfur mustard-associated oxidative stress via the CAV1/NRF2 signalling pathway.
Journal of cellular and molecular medicine.
2023 08; 27(15):2165-2182. doi:
10.1111/jcmm.17803. [PMID: 37386746] - Zhipeng Pei, Jinfeng Cen, Xinkang Zhang, Chuchu Gong, Mingxue Sun, Wenqi Meng, Guanchao Mao, Jingjing Wan, Bingyue Hu, Xiaowen He, Qingqiang Xu, Hua Han, Kai Xiao. MiR-146a-5p delivered by hucMSC extracellular vesicles modulates the inflammatory response to sulfur mustard-induced acute lung injury.
Stem cell research & therapy.
2023 05; 14(1):149. doi:
10.1186/s13287-023-03375-8. [PMID: 37254188] - Mirjam de Bruin-Hoegée, Latifa Lamriti, Jan P Langenberg, René C M Olivier, Lai Fun Chau, Marcel J van der Schans, Daan Noort, Arian C van Asten. Verification of exposure to chemical warfare agents through analysis of persistent biomarkers in plants.
Analytical methods : advancing methods and applications.
2023 01; 15(2):142-153. doi:
10.1039/d2ay01650h. [PMID: 36524843] - Ning Jiang, Pei Zhang, Wei Shen, Yongxiang Zhang, WenXia Zhou. Clinical and experimental research progress on neurotoxicity of sulfur mustard and its possible mechanisms.
Toxicology.
2023 01; 483(?):153372. doi:
10.1016/j.tox.2022.153372. [PMID: 36356660] - Leila Nasiri, Mohammad-Reza Vaez-Mahdavi, Hossein Hassanpour, Nayere Askari, Sussan Kaboudanian Ardestani, Tooba Ghazanfari. Concomitant use of relative telomere length, biological health score and physical/social statuses in the biological aging evaluation of mustard-chemical veterans.
International immunopharmacology.
2022 Aug; 109(?):108785. doi:
10.1016/j.intimp.2022.108785. [PMID: 35533552] - Wolfgang Schmeißer, Markus Siegert, Horst Thiermann, Theo Rein, Harald John. Highly stable peptide adducts from hard keratins as biomarkers to verify local sulfur mustard exposure of hair by high-resolution mass spectrometry.
Archives of toxicology.
2022 08; 96(8):2287-2298. doi:
10.1007/s00204-022-03307-0. [PMID: 35570235] - Harald John, Philipp Hörmann, Michael Schrader, Horst Thiermann. Alkylated glutamic acid and histidine derived from protein-adducts indicate exposure to sulfur mustard in avian serum.
Drug testing and analysis.
2022 Jun; 14(6):1140-1148. doi:
10.1002/dta.3236. [PMID: 35137544] - Bo Chen, Qiaoli Zhang, Zhe Ren, Tao Zhang, Huilan Yu, Changcai Liu, Yang Yang, Ping Xu, Shilei Liu. A proteomics strategy for the identification of multiple sites in sulfur mustard-modified HSA and screening potential biomarkers for retrospective analysis of exposed human plasma.
Analytical and bioanalytical chemistry.
2022 Jun; 414(14):4179-4188. doi:
10.1007/s00216-022-04070-y. [PMID: 35478034] - Yang Li, Shitong Han, Zhanguo Li, Zhen Liu, Longhui Liang, Keping Yan, Anna Zhu. Decontamination of 2-Chloroethyl ethyl sulfide on the surface by atmospheric pressure plasma jet.
Journal of hazardous materials.
2022 02; 424(Pt B):127536. doi:
10.1016/j.jhazmat.2021.127536. [PMID: 34879527] - Phillip H Beske, Christina M Wilhelm, Jill A Harvilchuck, Gennady E Platoff, David T Yeung. A Rodent Model of Sulfur Mustard Hematologic Toxicity for the Efficacy Evaluation of Candidate Medical Countermeasures.
Military medicine.
2022 01; 187(1-2):e106-e115. doi:
10.1093/milmed/usaa510. [PMID: 33346363] - Pirhossein Kolivand, Mohammad Fathi, Leila Kheyrati, Mehran Lak. Exposure to sulfur mustard increases the risk for mortality in patients with COVID-19 infection: A cohort study.
The American journal of emergency medicine.
2022 Jan; 51(?):144-149. doi:
10.1016/j.ajem.2021.09.053. [PMID: 34739867] - Abdorreza Vaezihir, Asra Pirkhezranian, Negar Sehati, Mohammad Reza Hosseinzadeh, Seyed Yahya Salehi-Lisar, Hans Sanderson. Investigation of long-term hazards of chemical weapon agents in the environment of Sardasht area, Iran.
Environmental science and pollution research international.
2022 Jan; 29(1):498-508. doi:
10.1007/s11356-021-15593-9. [PMID: 34333743] - Wolfgang Schmeißer, Robin Lüling, Dirk Steinritz, Horst Thiermann, Theo Rein, Harald John. Transthyretin as a target of alkylation and a potential biomarker for sulfur mustard poisoning: Electrophoretic and mass spectrometric identification and characterization.
Drug testing and analysis.
2022 Jan; 14(1):80-91. doi:
10.1002/dta.3146. [PMID: 34397154] - Leila Nasiri, Mohammad-Reza Vaez-Mahdavi, Hossein Hassanpour, Sussan Kaboudanian Ardestani, Nayere Askari. Sulfur mustard and biological ageing: A multisystem biological health score approach as an extension of the allostatic load in Sardasht chemical veterans.
International immunopharmacology.
2021 Dec; 101(Pt B):108375. doi:
10.1016/j.intimp.2021.108375. [PMID: 34810125] - Qichao Ye, Chen Men, Lili Tian, Yuxin Liu, Lei Zhan, Yuan Fang Li, Cheng Zhi Huang, Shu Jun Zhen. Preparation of a molecularly imprinted test strip for point-of-care detection of thiodiglycol, a sulfur mustard poisoning metabolic marker.
Talanta.
2021 Nov; 234(?):122701. doi:
10.1016/j.talanta.2021.122701. [PMID: 34364498] - Angela Cruz-Hernandez, Ryan P Mendoza, Kathleen Nguyen, Anna Harder, Christopher M Evans, Alison K Bauer, Neera Tewari-Singh, Jared M Brown. Mast Cells Promote Nitrogen Mustard-Mediated Toxicity in the Lung Associated With Proinflammatory Cytokine and Bioactive Lipid Mediator Production.
Toxicological sciences : an official journal of the Society of Toxicology.
2021 10; 184(1):127-141. doi:
10.1093/toxsci/kfab107. [PMID: 34453837] - Marie Gilardoni, Daniel Léonço, Fanny Caffin, Fanny Gros-Désormeaux, Camille Eldin, David Béal, Sadia Ouzia, Christophe Junot, François Fenaille, Christophe Piérard, Thierry Douki. Evidence for the systemic diffusion of (2-chloroethyl)-ethyl-sulfide, a sulfur mustard analog, and its deleterious effects in brain.
Toxicology.
2021 10; 462(?):152950. doi:
10.1016/j.tox.2021.152950. [PMID: 34534560] - Rama Malaviya, Alyssa Bellomo, Elena Abramova, Claire R Croutch, Julie Roseman, Rick Tuttle, Eric Peters, Robert P Casillas, Vasanthi R Sunil, Jeffrey D Laskin, Debra L Laskin. Pulmonary injury and oxidative stress in rats induced by inhaled sulfur mustard is ameliorated by anti-tumor necrosis factor-α antibody.
Toxicology and applied pharmacology.
2021 10; 428(?):115677. doi:
10.1016/j.taap.2021.115677. [PMID: 34390737] - Harald John, Annika Richter, Horst Thiermann. Evidence of sulfur mustard poisoning by detection of the albumin-derived dipeptide biomarker C(-HETE)P after nicotinylation.
Drug testing and analysis.
2021 Sep; 13(9):1593-1602. doi:
10.1002/dta.3114. [PMID: 34145783] - Annika Richter, Markus Siegert, Horst Thiermann, Harald John. Alkylated albumin-derived dipeptide C(-HETE)P derivatized by propionic anhydride as a biomarker for the verification of poisoning with sulfur mustard.
Analytical and bioanalytical chemistry.
2021 Aug; 413(19):4907-4916. doi:
10.1007/s00216-021-03454-w. [PMID: 34215915] - Maria Hemme, Alex Fidder, Debora van der Riet-van Oeveren, Marcel J van der Schans, Daan Noort. Mass spectrometric analysis of adducts of sulfur mustard analogues to human plasma proteins: approach towards chemical provenancing in biomedical samples.
Analytical and bioanalytical chemistry.
2021 Jun; 413(15):4023-4036. doi:
10.1007/s00216-021-03354-z. [PMID: 33903945] - Patrick M McNutt, Kyle E M Kelly, Amber C Altvater, Marian R Nelson, Megan E Lyman, Sean O'Brien, Matthieu T Conroy, Celinia A Ondeck, Skylar M L Bodt, Sarah E Wolfe, Susan M Schulz, Denise M Kniffin, Nicole B Hall, Tracey A Hamilton. Dose-dependent emergence of acute and recurrent corneal lesions in sulfur mustard-exposed rabbit eyes.
Toxicology letters.
2021 May; 341(?):33-42. doi:
10.1016/j.toxlet.2021.01.016. [PMID: 33497768] - Dirk Steinritz, Robin Lüling, Markus Siegert, Julia Herbert, Harald Mückter, Christian D Taeger, Thomas Gudermann, Alexander Dietrich, Horst Thiermann, Harald John. Alkylated epidermal creatine kinase as a biomarker for sulfur mustard exposure: comparison to adducts of albumin and DNA in an in vivo rat study.
Archives of toxicology.
2021 04; 95(4):1323-1333. doi:
10.1007/s00204-021-03005-3. [PMID: 33635393] - Robin Lüling, Wolfgang Schmeißer, Markus Siegert, Harald Mückter, Alexander Dietrich, Horst Thiermann, Thomas Gudermann, Harald John, Dirk Steinritz. Identification of creatine kinase and alpha-1 antitrypsin as protein targets of alkylation by sulfur mustard.
Drug testing and analysis.
2021 Feb; 13(2):268-282. doi:
10.1002/dta.2916. [PMID: 32852113] - Marie Roser, David Béal, Camille Eldin, Leslie Gudimard, Fanny Caffin, Fanny Gros-Désormeaux, Daniel Léonço, François Fenaille, Christophe Junot, Christophe Piérard, Thierry Douki. Glutathione conjugates of the mercapturic acid pathway and guanine adduct as biomarkers of exposure to CEES, a sulfur mustard analog.
Analytical and bioanalytical chemistry.
2021 Feb; 413(5):1337-1351. doi:
10.1007/s00216-020-03096-4. [PMID: 33410976] - Mehdi Hassanpour, Fateme Hajihassani, Mina Abdollahpourasl, Omid Cheraghi, Nasser Aghamohamadzade, Reza Rahbargazi, Mohammad Nouri, Younes Pilehvar-Soltanahmadi, Nosratollah Zarghami, Abolfazl Akbarzadeh, Yunes Panahi, Amirhossein Sahebkar. Pathophysiological Effects of Sulfur Mustard on Skin and its Current Treatments: Possible Application of Phytochemicals.
Combinatorial chemistry & high throughput screening.
2021; 24(1):3-19. doi:
10.2174/1386207323666200717150414. [PMID: 32679016] - Timur Baygildiev, Mikhail Vokuev, Arcady Braun, Igor Rybalchenko, Igor Rodin. Monitoring of hydrolysis products of mustard gas, some sesqui- and oxy-mustards and other chemical warfare agents in a plant material by HPLC-MS/MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2021 Jan; 1162(?):122452. doi:
10.1016/j.jchromb.2020.122452. [PMID: 33264722] - Gholamreza Farnoosh, Mostafa Ghanei, Hossein Khorramdelazad, Gholamhossein Alishiri, Alireza Jalali Farahani, Alireza Shahriary, Seyed Reza Hosseini Zijoud. Are Iranian Sulfur Mustard Gas-Exposed Survivors More Vulnerable to SARS-CoV-2? Some Similarity in Their Pathogenesis.
Disaster medicine and public health preparedness.
2020 Dec; 14(6):826-832. doi:
10.1017/dmp.2020.156. [PMID: 32418550] - Tapasi Rana, Aamir Ahmad, Iram Zafar, Nithya Mariappan, Darshan Shimoga Chandrashekar, Tariq Hamid, Maroof Husain, Sooryanarayana Varambally, Shama Ahmad, Aftab Ahmad. MicroRNA-mediated inflammation and coagulation effects in rats exposed to an inhaled analog of sulfur mustard.
Annals of the New York Academy of Sciences.
2020 11; 1479(1):148-158. doi:
10.1111/nyas.14416. [PMID: 32602122] - Ali Mohammad Mohseni Majd, Mehdi Alikhani, Mohammad Mehdi Naghizadeh, Tooba Ghazanfari. Two dimensional proteomic analysis of serum shows immunological proteins exclusively expressed in sulfur mustard exposed patients with long term pulmonary complications.
International immunopharmacology.
2020 Nov; 88(?):106857. doi:
10.1016/j.intimp.2020.106857. [PMID: 32853926] - Sheena A Young, Benedict R Capacio. Gas Chromatography-Tandem Mass Spectrometry Verification of Sulfur Mustard Exposure in Humans through the Conversion of Protein Adducts to Free Sulfur Mustard.
Chemical research in toxicology.
2020 07; 33(7):1941-1949. doi:
10.1021/acs.chemrestox.0c00134. [PMID: 32567850] - Yue Liu, Zhiqiang Song, Xiaofei Chen, Zhenyu Zhu, Liming Zhang, Zhanying Hong, Yifeng Chai. Nuclear magnetic resonance-based plasma metabolomics revealed the protective effect of tea polyphenols on sulfur mustard-induced injury in rats.
Journal of pharmaceutical and biomedical analysis.
2020 Jul; 186(?):113278. doi:
10.1016/j.jpba.2020.113278. [PMID: 32380352] - Yi-Hua Jan, Diane E Heck, Debra L Laskin, Jeffrey D Laskin. DNA damage signaling in the cellular responses to mustard vesicants.
Toxicology letters.
2020 Jun; 326(?):78-82. doi:
10.1016/j.toxlet.2020.03.008. [PMID: 32173488] - Mohammad Reza Khazdair, Fariba Rezaeetalab, Houshang Rafatpanah, Mohammad Hossein Boskabady. The effect of Zataria multiflora on inflammatory cytokine and respiratory symptoms in veterans exposed to sulfur mustard.
Environmental science and pollution research international.
2020 Jun; 27(18):22451-22460. doi:
10.1007/s11356-020-08855-5. [PMID: 32314290] - Tooba Ghazanfari, Ali Mostafaie, Farideh Talebi, Mohammad Reza Vaez Mahdavi, Mohammad Ebrahim Yarmohammadi, Nayere Askari, Sakine Moaiedmohseni, Ali Mohammad Mohseni Majd, Ensie Sadat Mirsharif, Zeinab Ghazanfari, Zuhair Mohammad Hassan, Jalaledin Shams, Davoud Jamali, Soghrat Faghihzadeh. Alteration in serum levels of immunoglobulins in seriously eye-injured long-term following sulfur-mustard exposure.
International immunopharmacology.
2020 Mar; 80(?):105895. doi:
10.1016/j.intimp.2019.105895. [PMID: 31787572] - Hassan Ghasemi, Mohammad Ali Javadi, Sussan K Ardestani, Mahmoud Mahmoudi, Shahryar Pourfarzam, Mohammad Reza Vaez Mahdavi, Mohammad Ebrahim Yarmohammadi, Alireza Baradaran-Rafii, Khosro Jadidi, Shamsa Shariatpanahi, Maryam Rastin, Fatemeh Heidary, Maliheh Safavi, Ensie Sadat Mirsharif, Zahra Nasiri, Tooba Ghazanfari. Alteration in inflammatory mediators in seriously eye-injured war veterans, long-term after sulfur mustard exposure.
International immunopharmacology.
2020 Mar; 80(?):105897. doi:
10.1016/j.intimp.2019.105897. [PMID: 31685435] - Mohammad Reza Khazdair, Vahideh Ghorani, Azam Alavinezhad, Mohammad Hossein Boskabady. Effect of Zataria multiflora on serum cytokine levels and pulmonary function tests in sulfur mustard-induced lung disorders: A randomized double-blind clinical trial.
Journal of ethnopharmacology.
2020 Feb; 248(?):112325. doi:
10.1016/j.jep.2019.112325. [PMID: 31707049] - Vahid Siavashi, Hadi Cheraghi, Pirouz Pourmohammad, Parviz Nooshirvani, Sara Abdolahi, Amir Solghani, Seyed Mahdi Nassiri, Tooba Ghazanfari. Impairment of endothelial progenitor cells function in patient with mustard gas intoxication.
Inhalation toxicology.
2020 02; 32(3):131-140. doi:
10.1080/08958378.2020.1755396. [PMID: 32312128] - Sermet Sezigen, Rusen Koray Eyison, Ertugrul Kilic, Levent Kenar. Evidence of sulfur mustard exposure in victims of chemical terrorism by detection of urinary β-lyase metabolites.
Clinical toxicology (Philadelphia, Pa.).
2020 01; 58(1):36-44. doi:
10.1080/15563650.2019.1614190. [PMID: 31072153] - Hassan Ghasemi, Roya Yaraee, Soghrat Faghihzadeh, Mohammad Ghassemi-Broumand, Mahmoud Mahmoudi, Mahmoud Babaei, Mostafa Naderi, Maliheh Safavi, Zeinab Ghazanfari, Maryam Rastin, Shahrzad Zamani, Nafiseh Tabasi, Elham Faghihzadeh, Reza Gharebaghi, Zuhair Mohammad Hassan, Ensie Sadat Mirsharif, Tooba Ghazanfari. Tear and serum MMP-9 and serum TIMPs levels in the severe sulfur mustard eye injured exposed patients.
International immunopharmacology.
2019 Dec; 77(?):105812. doi:
10.1016/j.intimp.2019.105812. [PMID: 31677500] - Tooba Ghazanfari, Hassan Ghasemi, Roya Yaraee, Mahmoud Mahmoudi, Mohammad Ali Javadi, Mohammad Reza Soroush, Soghrat Faghihzadeh, Ali Mohammad Mohseni Majd, Raheleh Shakeri, Mahmoud Babaei, Fatemeh Heidary, Zuhair Mohammad Hassan. Tear and serum interleukin-8 and serum CX3CL1, CCL2 and CCL5 in sulfur mustard eye-exposed patients.
International immunopharmacology.
2019 Dec; 77(?):105844. doi:
10.1016/j.intimp.2019.105844. [PMID: 31669888] - Silpa Sabnam, Arttatrana Pal. Relevance of Erk1/2-PI3K/Akt signaling pathway in CEES-induced oxidative stress regulates inflammation and apoptosis in keratinocytes.
Cell biology and toxicology.
2019 12; 35(6):541-564. doi:
10.1007/s10565-019-09467-7. [PMID: 30805762] - Fatemeh Heidary, Sussan K Ardestani, Hassan Ghasemi, Mohammad Ali Javadi, Mahmoud Mahmoudi, Roya Yaraee, Jalaledin Shams, Faramarz Falahi, Mohamad Reza Sedighi Moghadam, Shamsa Shariatpanahi, Raheleh Shakeri, Mohammad Mehdi Naghizadeh, Tooba Ghazanfari. Alteration in serum levels of ICAM-1 and P-, E- and L-selectins in seriously eye-injured long-term following sulfur-mustard exposure.
International immunopharmacology.
2019 Nov; 76(?):105820. doi:
10.1016/j.intimp.2019.105820. [PMID: 31480003] - Fatemeh Heidary, Reza Gharebaghi, Hassan Ghasemi, Mohammad Reza Vaez Mahdavi, Sara Ghaffarpour, Mohammad Mehdi Naghizadeh, Tooba Ghazanfari. Angiogenesis modulatory factors in subjects with chronic ocular complications of Sulfur Mustard exposure: A case-control study.
International immunopharmacology.
2019 Nov; 76(?):105843. doi:
10.1016/j.intimp.2019.105843. [PMID: 31629219] - Ali Mohammad Mohseni Majd, Soghrat Faghihzadeh, Shahryar Pourfarzam, Marzieh Eghtedardoost, Davoud Jamali, Ensie Sadat Mirsharif, Razieh Dilmaghanian, Tooba Ghazanfari. Serum and sputum levels of IL-17, IL-21, TNFα and mRNA expression of IL-17 in sulfur mustard lung tissue with long term pulmonary complications (28 years after sulfur mustard exposure).
International immunopharmacology.
2019 Nov; 76(?):105828. doi:
10.1016/j.intimp.2019.105828. [PMID: 31630084] - Wenqi Meng, Mingxue Sun, Qingqiang Xu, Jinfeng Cen, Yongbing Cao, Zhenjiang Li, Kai Xiao. Development of a Series of Fluorescent Probes for the Early Diagnostic Imaging of Sulfur Mustard Poisoning.
ACS sensors.
2019 10; 4(10):2794-2801. doi:
10.1021/acssensors.9b01424. [PMID: 31549501] - Tooba Ghazanfari, Sara Ghaffarpour, Amina Kariminia, Eisa Salehi, Seyed Mahmoud Hashemi, Sussan Kaboudanian Ardestani, Keivan Gohari Moghadam, Ensieh Sadat Mirsharif, Razieh Dilmaghanian, Abbas Fadaei, Soghrat Faghihzadeh. Circulating mesenchymal stem cells in sulfur mustard-exposed patients with long-term pulmonary complications.
Toxicology letters.
2019 Sep; 312(?):188-194. doi:
10.1016/j.toxlet.2019.05.015. [PMID: 31095986] - Daryoush Hamidi Alamdari, B Fatemeh Nobakht, Mahdi Balali-Mood, Mohammad Reza Keramati, Amirhossein Sahebkar. Prooxidant-antioxidant balance in Iranian veterans exposed to mustard gas and its correlation with biochemical and hematological parameters.
Drug and chemical toxicology.
2019 Sep; 42(5):536-540. doi:
10.1080/01480545.2018.1459673. [PMID: 29683368] - Harald John, Marianne Koller, Franz Worek, Horst Thiermann, Markus Siegert. Forensic evidence of sulfur mustard exposure in real cases of human poisoning by detection of diverse albumin-derived protein adducts.
Archives of toxicology.
2019 07; 93(7):1881-1891. doi:
10.1007/s00204-019-02461-2. [PMID: 31069408] - Bo Chen, Hui-Lan Yu, Shi-Lei Liu, Chang-Cai Liu, Long-Hui Liang, Xin-Hai Li, Xiao-Sen Li, Ji-Na Wu, Yang Yang. A sensitive quantification approach for detection of HETE-CP adduct after benzyl chloroformate derivatization using ultra-high-pressure liquid chromatography tandem mass spectrometry.
Analytical and bioanalytical chemistry.
2019 Jun; 411(15):3405-3415. doi:
10.1007/s00216-019-01820-3. [PMID: 31011788] - Rusen Koray Eyison, Sermet Sezigen, Mesut Ortatatli, Levent Kenar. Optimized Gas Chromatography-Tandem Mass Spectrometry for 1,1'-sulfonylbis[2-(methylthio) ethane] Quantification in Human Urine.
Journal of chromatographic science.
2019 May; 57(5):397-402. doi:
10.1093/chromsci/bmz017. [PMID: 30882871] - Markus Siegert, Felix Gandor, Andreas Kranawetvogl, Hans Börner, Horst Thiermann, Harald John. Methionine329 in human serum albumin: A novel target for alkylation by sulfur mustard.
Drug testing and analysis.
2019 May; 11(5):659-668. doi:
10.1002/dta.2548. [PMID: 30468304] - Mohammad Reza Khazdair, Mohammad Hossein Boskabady. The effect of carvacrol on inflammatory mediators and respiratory symptoms in veterans exposed to sulfur mustard, a randomized, placebo-controlled trial.
Respiratory medicine.
2019 04; 150(?):21-29. doi:
10.1016/j.rmed.2019.01.020. [PMID: 30961947] - Hao Zhang, Yongchun Chen, Zhipeng Pei, Huanhuan Gao, Wenwen Shi, Mingxue Sun, Qingqiang Xu, Jie Zhao, Wenqi Meng, Kai Xiao. Protective effects of polydatin against sulfur mustard-induced hepatic injury.
Toxicology and applied pharmacology.
2019 03; 367(?):1-11. doi:
10.1016/j.taap.2019.01.013. [PMID: 30677423] - Mohammad Reza Khazdair, Mohammad Hossein Boskabady. A double-blind, randomized, placebo-controlled clinical trial on the effect of carvacrol on serum cytokine levels and pulmonary function tests in sulfur mustard induced lung injury.
Cytokine.
2019 01; 113(?):311-318. doi:
10.1016/j.cyto.2018.07.031. [PMID: 30075886] - Sussan Kaboudanian Ardestani, Ali Taravati, Zahra Kianmehr, Arash Hajizadeh Dastjerdi, Shahryar Pourfarzam, Mohammad Reza Soroush, Mohammad Mehdi Naghizadeh, Tooba Ghazanfari. Altered levels of GST activity, Vit C, TPX and Cu in individuals with long-term sulfur mustard-induced lung complications.
Inhalation toxicology.
2018 Nov; 30(13-14):483-491. doi:
10.1080/08958378.2018.1545809. [PMID: 30849252] - Bamdad Riahi-Zanjani, Mahdi Balali-Mood, Mahmoud Mahmoudi, Mahmood Sadeghi. Innate Immune System Status of Sulphur Mustard-Poisoned Iranian Veterans Three Decades after Exposure.
Basic & clinical pharmacology & toxicology.
2018 Nov; 123(5):635-639. doi:
10.1111/bcpt.13053. [PMID: 29888462] - Erica Manandhar, Adam Pay, Livia A Veress, Brian A Logue. Rapid analysis of sulfur mustard oxide in plasma using gas chromatography-chemical ionization-mass spectrometry for diagnosis of sulfur mustard exposure.
Journal of chromatography. A.
2018 Oct; 1572(?):106-111. doi:
10.1016/j.chroma.2018.08.035. [PMID: 30170867] - Effat Behravan, Seyed Adel Moallem, Fatemeh Kalalinia, Mahnaz Ahmadimanesh, Peter Blain, Paul Jowsey, Shahriar Khateri, Mohammad Mahdi Forghanifard, Mahdi BalaliMood. Telomere shortening associated with increased levels of oxidative stress in sulfur mustard-exposed Iranian veterans.
Mutation research. Genetic toxicology and environmental mutagenesis.
2018 Oct; 834(?):1-5. doi:
10.1016/j.mrgentox.2018.06.017. [PMID: 30173859] - Markus Siegert, Andreas Kranawetvogl, Horst Thiermann, Harald John. Glutathione as an antidote for sulfur mustard poisoning: Mass spectrometric investigations of its potency as a chemical scavenger.
Toxicology letters.
2018 Sep; 293(?):31-37. doi:
10.1016/j.toxlet.2017.12.013. [PMID: 29277572] - Hossein Behboudi, Sakineh Kazemi Noureini, Tooba Ghazanfari, Sussan K Ardestani. DNA damage and telomere length shortening in the peripheral blood leukocytes of 20 years SM-exposed veterans.
International immunopharmacology.
2018 Aug; 61(?):37-44. doi:
10.1016/j.intimp.2018.05.008. [PMID: 29803135] - Matthew D McGraw, Marilyn M Dysart, Tara B Hendry-Hofer, Paul R Houin, Jaqueline S Rioux, Rhonda B Garlick, Joan E Loader, Russell Smith, Danielle C Paradiso, Wesley W Holmes, Dana R Anderson, Carl W White, Livia A Veress. Bronchiolitis Obliterans and Pulmonary Fibrosis after Sulfur Mustard Inhalation in Rats.
American journal of respiratory cell and molecular biology.
2018 06; 58(6):696-705. doi:
10.1165/rcmb.2017-0168oc. [PMID: 29314868] - Mohammad Reza Khazdair, Omid Rajabi, Mahdi Balali-Mood, Farimah Beheshti, Mohammad Hossein Boskabady. The effect of Zataria multiflora on pulmonary function tests, hematological and oxidant/antioxidant parameters in sulfur mustard exposed veterans, a randomized doubled-blind clinical trial.
Environmental toxicology and pharmacology.
2018 Mar; 58(?):180-188. doi:
10.1016/j.etap.2018.01.006. [PMID: 29408760] - Markus Siegert, Andreas Kranawetvogl, Horst Thiermann, Harald John. N-Acetylcysteine as a chemical scavenger for sulfur mustard: New insights by mass spectrometry.
Drug testing and analysis.
2018 Feb; 10(2):243-253. doi:
10.1002/dta.2299. [PMID: 28879668] - Hua Xu, Zhongcai Gao, Peng Wang, Bin Xu, Yajiao Zhang, Long Long, Cheng Zong, Lei Guo, Weijian Jiang, Qinong Ye, Lili Wang, Jianwei Xie. Biological effects of adipocytes in sulfur mustard induced toxicity.
Toxicology.
2018 01; 393(?):140-149. doi:
10.1016/j.tox.2017.11.011. [PMID: 29129815] - Sedigheh Gharbi, Shahriar Khateri, Mohammad Reza Soroush, Mehdi Shamsara, Parisa Naeli, Ali Najafi, Eberhard Korsching, Seyed Javad Mowla. MicroRNA expression in serum samples of sulfur mustard veterans as a diagnostic gateway to improve care.
PloS one.
2018; 13(3):e0194530. doi:
10.1371/journal.pone.0194530. [PMID: 29566027] - Seyyedeh Soghra Mousavi, E Vahedi, M Shohrati, Y Panahi, S Parvin. Nocturnal serum melatonin levels in sulfur mustard exposed patients with sleep disorders.
Journal of the Royal Army Medical Corps.
2017 Dec; 163(6):411-415. doi:
10.1136/jramc-2016-000677. [PMID: 29146723] - Yunes Panahi, Seyyed Mahdi Rajaee, Amirhossein Sahebkar. Ocular Effects of Sulfur Mustard and Therapeutic Approaches.
Journal of cellular biochemistry.
2017 11; 118(11):3549-3560. doi:
10.1002/jcb.25892. [PMID: 28106291] - Matthew D McGraw, Christopher M Osborne, Emily J Mastej, Jorge A Di Paola, Dana R Anderson, Wesley W Holmes, Danielle C Paradiso, Rhonda B Garlick, Tara B Hendry-Hofer, Raymond C Rancourt, Russell W Smith, Carol Burns, Gates B Roe, Jacqueline S Rioux, Carl W White, Livia A Veress. Editor's Highlight: Pulmonary Vascular Thrombosis in Rats Exposed to Inhaled Sulfur Mustard.
Toxicological sciences : an official journal of the Society of Toxicology.
2017 10; 159(2):461-469. doi:
10.1093/toxsci/kfx151. [PMID: 28962529] - Xiaorui Zhang, Yizhou Mei, Tongxing Wang, Feng Liu, Ning Jiang, Wenxia Zhou, Yongxiang Zhang. Early oxidative stress, DNA damage and inflammation resulting from subcutaneous injection of sulfur mustard into mice.
Environmental toxicology and pharmacology.
2017 Oct; 55(?):68-73. doi:
10.1016/j.etap.2017.06.016. [PMID: 28830012] - Charlotte A Hall, Helen L Lydon, Christopher H Dalton, J Kevin Chipman, John S Graham, Robert P Chilcott. The percutaneous toxicokinetics of Sulphur mustard in a damaged skin porcine model and the evaluation of WoundStat™ as a topical decontaminant.
Journal of applied toxicology : JAT.
2017 09; 37(9):1036-1045. doi:
10.1002/jat.3453. [PMID: 28304107] - David J Barillo, Claire R Croutch, Frances Reid, Tara Culley, William Sosna, Julie Roseman. Blood and Tissue Silver Levels Following Application of Silver-Based Dressings to Sulfur Mustard Chemical Burns.
Journal of burn care & research : official publication of the American Burn Association.
2017 Sep; 38(5):e818-e823. doi:
10.1097/bcr.0000000000000493. [PMID: 28846576] - B Fatemeh Nobakht, Afsaneh Arefi Oskouie, Mostafa Rezaei-Tavirani, Rasoul Aliannejad, Salman Taheri, Fariba Fathi, Mohammad Taghi Naseri. NMR spectroscopy-based metabolomic study of serum in sulfur mustard exposed patients with lung disease.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2017 Jul; 22(5):413-419. doi:
10.1080/1354750x.2016.1203995. [PMID: 27319271] - Dan Yu, Yuan-Yuan Bei, Yuan Li, Wei Han, Yu-Xu Zhong, Fei Liu, Yu-Ling Zhao, Xiao-Ji Zhu, Jian Zhao. In vitro the differences of inflammatory and oxidative reactions due to sulfur mustard induced acute pulmonary injury underlying intraperitoneal injection and intratracheal instillation in rats.
International immunopharmacology.
2017 Jun; 47(?):78-87. doi:
10.1016/j.intimp.2017.02.013. [PMID: 28365508] - Martin J Bevan, Matthew T Wogen, Mark D Lunda, Stefan A Saravia. High throughput quantitative analysis of the β-lyase sulfur mustard metabolite, 1,1'-sulfonylbis[2-(methylsulfinyl)ethane] in urine via high performance liquid chromatography tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Apr; 1051(?):1-8. doi:
10.1016/j.jchromb.2017.02.030. [PMID: 28279874] - Chang-Cai Liu, Shi-Lei Liu, Hai-Ling Xi, Hui-Lan Yu, Shi-Kun Zhou, Gui-Lan Huang, Long-Hui Liang, Jing-Quan Liu. Simultaneous quantification of four metabolites of sulfur mustard in urine samples by ultra-high performance liquid chromatography-tandem mass spectrometry after solid phase extraction.
Journal of chromatography. A.
2017 Apr; 1492(?):41-48. doi:
10.1016/j.chroma.2017.02.056. [PMID: 28284764] - Satish Sagar, Soumya Ranjan Parida, Silpa Sabnam, Huma Rizwan, Sweta Pal, Mitali Madhusmita Swain, Arttatrana Pal. Increasing NO level regulates apoptosis and inflammation in macrophages after 2-chloroethyl ethyl sulphide challenge.
The international journal of biochemistry & cell biology.
2017 02; 83(?):1-14. doi:
10.1016/j.biocel.2016.12.004. [PMID: 27939754] - Nayere Askari, Tooba Ghazanfari, Roya Yaraee, Mohammad Reza Vaez Mahdavi, Mohammad-Reza Soroush, Zuhair Mohammad Hassan, Zohre Khodashenas, Jalaleddin Shams, Soghrat Faghihzadeh. Association between Acne and Serum Pro-inflammatory Cytokines (IL-1α, IL-1β, IL-1Ra, IL-6, IL-8, IL-12 and RANTES) in Mustard Gas-Exposed Patients: Sardasht-Iran Cohort Study.
Archives of Iranian medicine.
2017 Feb; 20(2):86-91. doi:
0172002/aim.005. [PMID: 28193081] - Sara Ghaffarpour, Tooba Ghazanfari, Sussan Kabudanian Ardestani, Shahryar Pourfarzam, Faramarz Fallahi, Jalaleddin Shams, Ensieh Sadat Mirsharif, Ali Mohammad Mohseni Majd, Soghrat Faghihzadeh. Correlation between MMP-9 and MMP-9/ TIMPs Complex with Pulmonary Function in Sulfur Mustard Exposed Civilians: Sardasht-Iran Cohort Study.
Archives of Iranian medicine.
2017 Feb; 20(2):74-82. doi:
0172002/aim.003. [PMID: 28193079] - Yunes Panahi, Mostafa Ghanei, Ensieh Vahedi, Seyyed Hossein Mousavi, Saber Imani, Amirhossein Sahebkar. Efficacy of probiotic supplementation on quality of life and pulmonary symptoms due to sulfur mustard exposure: a randomized double-blind placebo-controlled trial.
Drug and chemical toxicology.
2017 Jan; 40(1):24-29. doi:
10.3109/01480545.2016.1166250. [PMID: 27079636] - Amir Nejad-Moghaddam, Sohiela Ajdary, Eisa Tahmasbpour, Farhad Riazi Rad, Yunes Panahi, Mostafa Ghanei. Immunomodulatory Properties of Mesenchymal Stem Cells Can Mitigate Oxidative Stress and Inflammation Process in Human Mustard Lung.
Biochemical genetics.
2016 Dec; 54(6):769-783. doi:
10.1007/s10528-016-9755-8. [PMID: 27484501] - Cameron S McElroy, Elysia Min, Jie Huang, Joan E Loader, Tara B Hendry-Hofer, Rhonda B Garlick, Jackie S Rioux, Livia A Veress, Russell Smith, Chris Osborne, Dana R Anderson, Wesley W Holmes, Danielle C Paradiso, Carl W White, Brian J Day. From the Cover: Catalytic Antioxidant Rescue of Inhaled Sulfur Mustard Toxicity.
Toxicological sciences : an official journal of the Society of Toxicology.
2016 12; 154(2):341-353. doi:
10.1093/toxsci/kfw170. [PMID: 27605419] - B Fatemeh Nobakht M Gh, Afsaneh Arefi Oskouie, Rasoul Aliannejad, Mostafa Rezaei-Tavirani, Shima Tavallaie, Alireza Akbarzadeh Baghban, Salman Taheri, Mohammad Reza Keramati, Daryoush Hamidi Alamdari. Pro-oxidant-antioxidant balance in Iranian veterans with sulfur mustard toxicity and different levels of pulmonary disorders.
Drug and chemical toxicology.
2016 Oct; 39(4):362-6. doi:
10.3109/01480545.2015.1122033. [PMID: 26679093] - Harald John, Sophia Willoh, Philipp Hörmann, Markus Siegert, Antje Vondran, Horst Thiermann. Procedures for Analysis of Dried Plasma Using Microsampling Devices to Detect Sulfur Mustard-Albumin Adducts for Verification of Poisoning.
Analytical chemistry.
2016 09; 88(17):8787-94. doi:
10.1021/acs.analchem.6b02199. [PMID: 27482832] - Alessandro Sassolini, Giampaolo Brinchi, Antonio Di Gennaro, Simone Dionisi, Carola Dominici, Luca Fantozzi, Giorgio Onofri, Rosario Piazza, Maurizio Guidotti. Evaluation of Molecular Markers and Analytical Methods Documenting the Occurrence of Mustard Gas and Arsenical Warfare Agents in Soil.
Bulletin of environmental contamination and toxicology.
2016 Sep; 97(3):432-8. doi:
10.1007/s00128-016-1860-1. [PMID: 27385368] - B Fatemeh Nobakht, Rasoul Aliannejad, Mostafa Rezaei-Tavirani, Afsaneh Arefi Oskouie, Mohammad Taghi Naseri, Hadi Parastar, Ghazaleh Aliakbarzadeh, Fariba Fathi, Salman Taheri. NMR- and GC/MS-based metabolomics of sulfur mustard exposed individuals: a pilot study.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2016 Sep; 21(6):479-89. doi:
10.3109/1354750x.2016.1153725. [PMID: 26984270] - Dirk Steinritz, Enno Striepling, Klaus-Dieter Rudolf, Claudia Schröder-Kraft, Klaus Püschel, Andreas Hullard-Pulstinger, Marianne Koller, Horst Thiermann, Felix Gandor, Michael Gawlik, Harald John. Medical documentation, bioanalytical evidence of an accidental human exposure to sulfur mustard and general therapy recommendations.
Toxicology letters.
2016 Feb; 244(?):112-120. doi:
10.1016/j.toxlet.2015.08.1105. [PMID: 26321678] - Harald John, Markus Siegert, Felix Gandor, Michael Gawlik, Andreas Kranawetvogl, Konstantin Karaghiosoff, Horst Thiermann. Optimized verification method for detection of an albumin-sulfur mustard adduct at Cys(34) using a hybrid quadrupole time-of-flight tandem mass spectrometer after direct plasma proteolysis.
Toxicology letters.
2016 Feb; 244(?):103-111. doi:
10.1016/j.toxlet.2015.09.027. [PMID: 26449527] - Yunes Panahi, Mostafa Ghanei, Ali Hajhashemi, Amirhossein Sahebkar. Effects of Curcuminoids-Piperine Combination on Systemic Oxidative Stress, Clinical Symptoms and Quality of Life in Subjects with Chronic Pulmonary Complications Due to Sulfur Mustard: A Randomized Controlled Trial.
Journal of dietary supplements.
2016; 13(1):93-105. doi:
10.3109/19390211.2014.952865. [PMID: 25171552] - G M Kannan, Pravin Kumar, A S B Bhaskar, U Pathak, Deo Kumar, D P Nagar, S C Pant, K Ganesan. Prophylactic efficacy of S-2(2-aminoethylamino)ethyl phenyl sulfide (DRDE-07) against sulfur mustard induced lung toxicity in mice.
Drug and chemical toxicology.
2016; 39(2):182-9. doi:
10.3109/01480545.2015.1070169. [PMID: 26247826] - Zahra Zamani, Mostafa Ghanei, Yunus Panahi, Mohammad Arjmand, Sedigheh Sadeghi, Fatemeh Mirkhani, Shahram Parvin, Maryam Salehi, Amirhossein Sahebkar, Farideh Vahabi. Serum Metabolomic Profiling of Sulphur Mustard-Exposed Individuals Using (1)H Nuclear Magnetic Resonance Spectroscopy.
Basic & clinical pharmacology & toxicology.
2016 Jan; 118(1):77-82. doi:
10.1111/bcpt.12441. [PMID: 26177671] - Jin Young Lee, Yong Han Lee. Solid-Phase Extraction of Sulfur Mustard Metabolites Using an Activated Carbon Fiber Sorbent.
Journal of analytical toxicology.
2016 Jan; 40(1):64-71. doi:
10.1093/jat/bkv112. [PMID: 26364317] - Y Panahi, M Ghanei, S Bashiri, A Hajihashemi, A Sahebkar. Short-term Curcuminoid Supplementation for Chronic Pulmonary Complications due to Sulfur Mustard Intoxication: Positive Results of a Randomized Double-blind Placebo-controlled Trial.
Drug research.
2015 Nov; 65(11):567-73. doi:
10.1055/s-0034-1389986. [PMID: 25268878] - ChangCai Liu, LongHui Liang, Yu Xiang, HuiLan Yu, ShiKun Zhou, HaiLing Xi, ShiLei Liu, JingQuan Liu. An improved method for retrospective quantification of sulfur mustard exposure by detection of its albumin adduct using ultra-high pressure liquid chromatography-tandem mass spectrometry.
Analytical and bioanalytical chemistry.
2015 Sep; 407(23):7037-46. doi:
10.1007/s00216-015-8842-8. [PMID: 26164303] - Felix Gandor, Michael Gawlik, Horst Thiermann, Harald John. Evidence of Sulfur Mustard Exposure in Human Plasma by LC-ESI-MS-MS Detection of the Albumin-Derived Alkylated HETE-CP Dipeptide and Chromatographic Investigation of Its Cis/Trans Isomerism.
Journal of analytical toxicology.
2015 May; 39(4):270-9. doi:
10.1093/jat/bkv010. [PMID: 25712440] - Mohamed Batal, Silvestre Rebelo-Moreira, Nadège Hamon, Pierre-Alain Bayle, Stéphane Mouret, Cécile Cléry-Barraud, Isabelle Boudry, Thierry Douki. A guanine-ethylthioethyl-glutathione adduct as a major DNA lesion in the skin and in organs of mice exposed to sulfur mustard.
Toxicology letters.
2015 Feb; 233(1):1-7. doi:
10.1016/j.toxlet.2015.01.001. [PMID: 25562541] - Brooke G Pantazides, Brian S Crow, Joshua W Garton, Jennifer A Quiñones-González, Thomas A Blake, Jerry D Thomas, Rudolph C Johnson. Simplified Method for Quantifying Sulfur Mustard Adducts to Blood Proteins by Ultrahigh Pressure Liquid Chromatography−Isotope Dilution Tandem Mass Spectrometry.
Chemical research in toxicology.
2015 Feb; 28(2):256-61. doi:
10.1021/tx500468h. [PMID: 25622494] - Igor Rodin, Arcady Braun, Andrey Stavrianidi, Timur Baygildiev, Oleg Shpigun, Dmitry Oreshkin, Igor Rybalchenko. 'Dilute-and-shoot' RSLC-MS-MS method for fast detection of nerve and vesicant chemical warfare agent metabolites in urine.
Journal of analytical toxicology.
2015 Jan; 39(1):69-74. doi:
10.1093/jat/bku119. [PMID: 25326204] - Mohammad Reza Nourani, Hamideh Mahmoodzadeh Hosseini, Abbas Ali Imani Fooladi. Comparative transcriptional and translational analysis of heme oxygenase expression in response to sulfur mustard.
Journal of receptor and signal transduction research.
2015; 35(5):479-84. doi:
10.3109/10799893.2015.1015735. [PMID: 26096165]