Exact Mass: 157.0869
Exact Mass Matches: 157.0869
Found 500 metabolites which its exact mass value is equals to given mass value 157.0869,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
3-Methylcrotonylglycine
3-Methylcrotonylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine. 3-Methylcrotonylglycine is a normal amino acid metabolite found in urine. Increased levels of this metabolite are found in patients suffering from leucine catabolic disorders, such as 3-methylcrotonyl-CoA carboxylase deficiency. 3-Methylcrotonylglycine is often considered to be a diagnostic marker of organic acidemias (PMID 11170888). Moreover, 3-methylcrotonylglycine is found to be associated with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency and propionic acidemia, which are also inborn errors of metabolism. 3-Methylcrotonylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: 3-Methylcrotonylglycine is an acyl glycine, a normal amino acid metabolite found in urine.
Tranexamic Acid
Tranexamic Acid is only found in individuals that have used or taken this drug. It is an antifibrinolytic hemostatic used in severe hemorrhage. [PubChem]Tranexamic acid competitively inhibits activation of plasminogen (via binding to the kringle domain), thereby reducing conversion of plasminogen to plasmin (fibrinolysin), an enzyme that degrades fibrin clots, fibrinogen, and other plasma proteins, including the procoagulant factors V and VIII. Tranexamic acid also directly inhibits plasmin activity, but higher doses are required than are needed to reduce plasmin formation. B - Blood and blood forming organs > B02 - Antihemorrhagics > B02A - Antifibrinolytics > B02AA - Amino acids COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics C78275 - Agent Affecting Blood or Body Fluid > C78311 - Hemostatic Agent D050299 - Fibrin Modulating Agents > D000933 - Antifibrinolytic Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Tranexamic acid (cyclocapron), a cyclic analog of lysine, is an orally active antifibrinolytic agent. Tranexamic acid attenuates the effects of severe trauma, inhibits urokinase plasminogen activator and ameliorates dry wrinkles. Tranexamic acid can used for the research of hemostasis [1][2][3][4][5].
(S)-Homostachydrine
(S)-Homostachydrine (also known as pipecolic acid betaine or homostachydrine) can be found in green coffee beans of Robusta and Arabica species (PMID: 27006213). (S)-Homostachydrine content is unaffected by coffee bean roasting treatment because of its remarkable heat stability. This makes it a good candidate marker for determining the content of Robusta and Arabica species in roasted coffee blends. (S)-Homostachydrine is also a potential marker of coffee consumption as it can be found in both human serum and human urine. It is also found in alfalfa seeds and leaves. More specifically, (S)-homostachydrine can be isolated from the seeds of Medicago sativa (alfalfa) as well as from Achillea millefolium (yarrow). (S)-Homostachydrine is also found in the fruits, seeds, and leaves of orange, lemon, and bergamot (PMID: 22208890). Isolated from seeds of Medicago sativa (alfalfa)and is also from Achillea millefolium (yarrow). (S)-Homostachydrine is found in alfalfa, herbs and spices, and pulses.
Paramethadione
Paramethadione is only found in individuals that have used or taken this drug. It is an anticonvulsant in the oxazolidinedione class. It is associated with fetal trimethadione syndrome, which is also known as paramethadione syndrome.Dione anticonvulsants such as paramethadione reduce T-type calcium currents in thalamic neurons (including thalamic relay neurons). This inhibits corticothalamic transmission and raises the threshold for repetitive activity in the thalamus. This results in a dampening of the abnormal thalamocortical rhythmicity proposed to underlie the 3-Hz spike-and-wave discharge seen on electroencephalogram (EEG) during absence seizures. N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics > N03AC - Oxazolidine derivatives C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent
Hydroxyethylclavam
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
Tiglylglycine
Tiglylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine. Tiglylglycine is an intermediate product of the catabolism of isoleucine. An elevated level of tiglylglycine is identified in urine of patients with beta-ketothiolase deficiency or with disorders of propionate metabolism (PMID 7923765). Tiglyglycine is a biomarker for the consumption of cheese. Tiglylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:
N-Acetylproline
N-Acetyl-L-proline or N-Acetylproline, belongs to the class of organic compounds known as N-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. N-Acetylproline can also be classified as an alpha amino acid or a derivatized alpha amino acid. Technically, N-Acetylproline is a biologically available N-terminal capped form of the proteinogenic alpha amino acid L-proline. N-acetyl amino acids can be produced either via direct synthesis of specific N-acetyltransferases or via the proteolytic degradation of N-acetylated proteins by specific hydrolases. N-terminal acetylation of proteins is a widespread and highly conserved process in eukaryotes that is involved in protection and stability of proteins (PMID: 16465618). About 85\\% of all human proteins and 68\\% of all yeast proteins are acetylated at their N-terminus (PMID: 21750686). Several proteins from prokaryotes and archaea are also modified by N-terminal acetylation. The majority of eukaryotic N-terminal-acetylation reactions occur through N-acetyltransferase enzymes or NAT’s (PMID: 30054468). These enzymes consist of three main oligomeric complexes NatA, NatB, and NatC, which are composed of at least a unique catalytic subunit and one unique ribosomal anchor. The substrate specificities of different NAT enzymes are mainly determined by the identities of the first two N-terminal residues of the target protein. The human NatA complex co-translationally acetylates N-termini that bear a small amino acid (A, S, T, C, and occasionally V and G) (PMID: 30054468). NatA also exists in a monomeric state and can post-translationally acetylate acidic N-termini residues (D-, E-). NatB and NatC acetylate N-terminal methionine with further specificity determined by the identity of the second amino acid. N-acetylated amino acids, such as N-acetylproline can be released by an N-acylpeptide hydrolase from peptides generated by proteolytic degradation (PMID: 16465618). In addition to the NAT enzymes and protein-based acetylation, N-acetylation of free proline can also occur. Many N-acetylamino acids, including N-acetylproline are classified as uremic toxins if present in high abundance in the serum or plasma (PMID: 26317986; PMID: 20613759). Uremic toxins are a diverse group of endogenously produced molecules that, if not properly cleared or eliminated by the kidneys, can cause kidney damage, cardiovascular disease and neurological deficits (PMID: 18287557).
7-(Methylthio)heptanenitrile
7-(Methylthio)heptanenitrile is found in brassicas. 7-(Methylthio)heptanenitrile is a constituent of Wasabia japonica (Japanese horseradish)
2,4-Dimethylquinoline
2,4-dimethylquinoline belongs to quinolines and derivatives class of compounds. Those are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene. 2,4-dimethylquinoline is practically insoluble (in water) and a very strong basic compound (based on its pKa). 2,4-dimethylquinoline can be found in tea, which makes 2,4-dimethylquinoline a potential biomarker for the consumption of this food product.
2,6-Dimethylquinoline
2,6-dimethylquinoline belongs to quinolines and derivatives class of compounds. Those are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene. 2,6-dimethylquinoline is practically insoluble (in water) and a very strong basic compound (based on its pKa). 2,6-dimethylquinoline can be found in tea, which makes 2,6-dimethylquinoline a potential biomarker for the consumption of this food product. 2,6-Dimethylquinoline belongs to the class of organic compounds known as quinolines and derivatives. Quinolines and derivatives are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene. 2,6-Dimethylquinoline is a dimethylated derivative of quinoline. Quinoline is a colourless hygroscopic Liquid with a strong odour.
4,8-Dimethylquinoline
4,8-dimethylquinoline belongs to quinolines and derivatives class of compounds. Those are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene. 4,8-dimethylquinoline is practically insoluble (in water) and a very strong basic compound (based on its pKa). 4,8-dimethylquinoline can be found in tea, which makes 4,8-dimethylquinoline a potential biomarker for the consumption of this food product.
N-methylbenzylamine hydrochloride
2-Amino-4-hydroxy-6-heptynoic acid|2-Amino-4-hydroxy-hept-6-yn-carbonsaeure
3-Methyl-Delta2-dihydromuconsaeure-1-amid|5-carbamoyl-4-methyl-pent-4-enoic acid|5-Carbamoyl-4-methyl-pent-4-ensaeure
2,6-Dimethylquinoline
2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 μM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 μM[1][2][3]. 2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 μM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 μM[1][2][3].
AI3-03277
2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 μM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 μM[1][2][3]. 2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 μM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 μM[1][2][3].
Tiglylglycine
An N-acylglycine that is glycine with an amine hydrogen substituted by a 2-methylbut-2-enoyl (tiglyl) group. Acquisition and generation of the data is financially supported in part by CREST/JST.
3-Methylcrotonylglycine
3-Methylcrotonylglycine is an acyl glycine, a normal amino acid metabolite found in urine.
Homostachydrine
An ammonium betaine that is pipecolic acid zwitterion with methyl groups substituted for the two hydrogens at the nitrogen. It is found in in fruits, seeds, and leaves of orange, lemon, and bergamot. MS2 deconvoluted using MS2Dec from all ion fragmentation data, MetaboLights identifier MTBLS1040; XULZWQRXYTVUTE-ZETCQYMHSA-N_STSL_0043_pipecolic acid betaine_0125fmol_180407_S2_LC02_MS02_96; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I. MS2 deconvoluted using CorrDec from all ion fragmentation data, MetaboLights identifier MTBLS1040; Spectrum acquired as described in Naz et al 2017 PMID 28641411. Preparation and submission to MassBank of North America by Chaleckis R. and Tada I.
N-(Butoxymethyl)acrylamide
ORIGINAL_PRECURSOR_SCAN_NO 10594; CONFIDENCE standard compound; INTERNAL_ID 975; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10597 CONFIDENCE standard compound; INTERNAL_ID 975; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10597; ORIGINAL_PRECURSOR_SCAN_NO 10594 CONFIDENCE standard compound; INTERNAL_ID 975; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 14643; ORIGINAL_PRECURSOR_SCAN_NO 14641 CONFIDENCE standard compound; INTERNAL_ID 942; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10597; ORIGINAL_PRECURSOR_SCAN_NO 10594 CONFIDENCE standard compound; INTERNAL_ID 942; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 14643; ORIGINAL_PRECURSOR_SCAN_NO 14641
tranexamic acid
B - Blood and blood forming organs > B02 - Antihemorrhagics > B02A - Antifibrinolytics > B02AA - Amino acids COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics C78275 - Agent Affecting Blood or Body Fluid > C78311 - Hemostatic Agent D050299 - Fibrin Modulating Agents > D000933 - Antifibrinolytic Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Tranexamic acid (cyclocapron), a cyclic analog of lysine, is an orally active antifibrinolytic agent. Tranexamic acid attenuates the effects of severe trauma, inhibits urokinase plasminogen activator and ameliorates dry wrinkles. Tranexamic acid can used for the research of hemostasis [1][2][3][4][5].
Ethosuximide M6, 2-(1-Hydroxyethyl)-2-methylsuccinimide
Isoxazole, 3,5-dimethyl-4-[(methylthio)methyl]- (9CI)
Cyclohexanecarboxylic acid, 3-amino-, Methyl ester
2-Piperidinecarboxylicacid, 1-methyl-, methyl ester
3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-4-hydroxy-, methyl ester (9CI)
4,4,5,6,7,7-hexadeuterio-3a,7a-dihydroisoindole-1,3-dione
Cyclohexanecarboxylic acid, 4-amino-, methyl ester (9CI)
1H-Azepine-4-carboxaldehyde, hexahydro-3-hydroxy-2-oxo- (9CI)
2-(Dimethylamino)ethyl methacrylate
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D019163 - Reducing Agents
2,4-Dihydro-5-propoxy-4-methyl-3H-1,2,4-Triazol-3-one
Quinoline, 1,2-dihydro-1-methyl-2-methylene- (8CI,9CI)
1H-Azepine-3-carboxylicacid,hexahydro-,methylester(9CI)
1H-Imidazole-4-carboxylicacid,5-amino-4,5-dihydro-,ethylester(9CI)
6-aminodihydro-1,3-dimethyl-2,4(1H,3H) –pyrimidinedione
1H-Azepine-4-carboxylic acid, hexahydro-, methyl ester
5-sec-butyl-1,3,4-thiadiazol-2-amine(SALTDATA: FREE)
Thiazole, 2,5-dihydro-4,5-dimethyl-2-(1-methylethyl)-, trans- (9CI)
Thiazole, 2,5-dihydro-2,2-dimethyl-5-(1-methylethyl)- (9CI)
Cycloheptanecarboxylic acid, 2-amino-, (1S,2R)- (9CI)
Cyclopropanecarboxylic acid, 2-[(ethylamino)carbonyl]- (9CI)
1H-Imidazole-1-aceticacid,2-amino-4,5-dihydro-,methylester(9CI)
1H-1,2,4-Triazole-3-carboxylic acid,5-hydrazino-,hydrazide (9CI)
Ethanamine,2-(ethenyloxy)-N-[2-(ethenyloxy)ethyl]-
3H-1,2,4-Triazole-3-thione,2,4-dihydro-4-methyl-5-(1-methylethyl)-(9CI)
(1S,2S)-2-aminocyclohexanecarboxylic acid methyl ester
methyl 4-methyl-4-piperidinecarboxylate(SALTDATA: HCl)
Pyrrolidine, 1-hydroxy-2-[(2-propenyloxy)methyl]-, (2S)- (9CI)
(3r,6s)-3-piperidinecarboxylic acid, 6-methyl-, methyl ester
(2S)-3-(3-ACETYL-4-HYDROXYPHENYL)-2-AMINOPROPANOICACID
Cyclopentanecarboxylic acid, 2-amino-, ethyl ester, (1S-trans)- (9CI)
L-xylo-Hept-4-enonic acid, 2-amino-3,6-anhydro-2,4,5,7-tetradeoxy-
O2-Vinyl 1-(Pyrrolidin-1-yl)diazen-1-ium-1,2-diolate
paramethadione (500 mg)
N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics > N03AC - Oxazolidine derivatives C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent
furanomycin
A non-proteinogenic L-alpha-amino acid that is L-alanine in which the methyl group is replaced by a (2R,5S)-5-methyl-2,5-dihydrofuran-2-yl moiety.
3-Methylcrotonyl glycine
An N-acylglycine in which the acyl group is specified as 3-methylbut-2-enoyl.
ethyl (2s)-5-hydroxy-3,4-dihydro-2h-pyrrole-2-carboxylate
(1r,3r,5s,6r)-8-methyl-8-azabicyclo[3.2.1]octane-3,6-diol
2-epilentiginosine
{"Ingredient_id": "HBIN005585","Ingredient_name": "2-epilentiginosine","Alias": "NA","Ingredient_formula": "C8H15NO2","Ingredient_Smile": "C1CCN2CC(C(C2C1)O)O","Ingredient_weight": "157.21 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "8660","PubChem_id": "11084135","DrugBank_id": "NA"}
