1-Methyl-4-piperidyl acetate (BioDeep_00000172240)

   

human metabolite blood metabolite


代谢物信息卡片


1-Methyl-4-piperidyl acetate, hydrochloride

化学式: C8H15NO2 (157.110273)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)OC1CCN(CC1)C
InChI: InChI=1S/C8H15NO2/c1-7(10)11-8-3-5-9(2)6-4-8/h8H,3-6H2,1-2H3

描述信息

同义名列表

6 个代谢物同义名

1-Methyl-4-piperidyl acetate, hydrochloride; 1-Methyl-4-piperidyl acetate, (14C)-labeled; 1-Methyl-4-piperidyl acetic acid; 1-methylpiperidin-4-yl acetate; 1-Methyl-4-piperidyl acetate; m4p Acetate



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tsuneyoshi Ota, Hitoshi Shinotoh, Kiyoshi Fukushi, Tatsuya Kikuchi, Koichi Sato, Noriko Tanaka, Hitoshi Shimada, Shigeki Hirano, Michie Miyoshi, Heii Arai, Tetsuya Suhara, Toshiaki Irie. Estimation of plasma IC50 of donepezil for cerebral acetylcholinesterase inhibition in patients with Alzheimer disease using positron emission tomography. Clinical neuropharmacology. 2010 Mar; 33(2):74-8. doi: 10.1097/wnf.0b013e3181c71be9. [PMID: 19935404]
  • Tetsuya Shiraishi, Tatsuya Kikuchi, Kiyoshi Fukushi, Hitoshi Shinotoh, Shin-ichiro Nagatsuka, Noriko Tanaka, Tsuneyoshi Ota, Koichi Sato, Shigeki Hirano, Shuji Tanada, Masaomi Iyo, Toshiaki Irie. Estimation of plasma IC50 of donepezil hydrochloride for brain acetylcholinesterase inhibition in monkey using N-[11C]methylpiperidin-4-yl acetate ([11C]MP4A) and PET. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2005 Dec; 30(12):2154-61. doi: 10.1038/sj.npp.1300759. [PMID: 15920507]
  • Ming-Rong Zhang, Kenji Furutsuka, Jun Maeda, Tatsuya Kikuchi, Takayo Kida, Takashi Okauchi, Toshiaki Irie, Kazutoshi Suzuki. N-[18F]fluoroethyl-4-piperidyl acetate ([18F]FEtP4A): A PET tracer for imaging brain acetylcholinesterase in vivo. Bioorganic & medicinal chemistry. 2003 Jun; 11(12):2519-27. doi: 10.1016/s0968-0896(03)00177-9. [PMID: 12757720]
  • Hiroki Namba, Kiyoshi Fukushi, Shin-ichiro Nagatsuka, Masaomi Iyo, Hitoshi Shinotoh, Shuji Tanada, Toshiaki Irie. Positron emission tomography: quantitative measurement of brain acetylcholinesterase activity using radiolabeled substrates. Methods (San Diego, Calif.). 2002 Jul; 27(3):242-50. doi: 10.1016/s1046-2023(02)00081-6. [PMID: 12183113]
  • S Nagatsuka Si, K Fukushi, H Shinotoh, H Namba, M Iyo, N Tanaka, A Aotsuka, T Ota, S Tanada, T Irie. Kinetic analysis of [(11)C]MP4A using a high-radioactivity brain region that represents an integrated input function for measurement of cerebral acetylcholinesterase activity without arterial blood sampling. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2001 Nov; 21(11):1354-66. doi: 10.1097/00004647-200111000-00011. [PMID: 11702050]
  • K Herholz, M Lercher, K Wienhard, B Bauer, O Lenz, W D Heiss. PET measurement of cerebral acetylcholine esterase activity without blood sampling. European journal of nuclear medicine. 2001 Apr; 28(4):472-7. doi: 10.1007/s002590100492. [PMID: 11357497]