Glycine, N-[(2E)-2-methyl-1-oxo-2-butenyl]- (BioDeep_00000175701)
human metabolite blood metabolite
代谢物信息卡片
化学式: C7H11NO3 (157.0739)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: CC=C(C)C(=O)NCC(=O)O
InChI: InChI=1S/C7H11NO3/c1-3-5(2)7(11)8-4-6(9)10/h3H,4H2,1-2H3,(H,8,11)(H,9,10)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Avalyn Stanislaus, Kevin Guo, Liang Li. Development of an isotope labeling ultra-high performance liquid chromatography mass spectrometric method for quantification of acylglycines in human urine.
Analytica chimica acta.
2012 Oct; 750(?):161-72. doi:
10.1016/j.aca.2012.05.006. [PMID: 23062437] - Vefik Arica, Secil Gunher Arica, Huseyin Dag, Hatice Onur, Omer Obut, Sayat Gülbayzar. Beta-ketothiolase deficiency brought with lethargy: case report.
Human & experimental toxicology.
2011 Oct; 30(10):1724-7. doi:
10.1177/0960327110396533. [PMID: 21247997] - Kyriakie Sarafoglou, Dietrich Matern, Krista Redlinger-Grosse, Kristi Bentler, Amy Gaviglio, Cary O Harding, Piero Rinaldo. Siblings with mitochondrial acetoacetyl-CoA thiolase deficiency not identified by newborn screening.
Pediatrics.
2011 Jul; 128(1):e246-50. doi:
10.1542/peds.2010-3918. [PMID: 21669895] - Laurie H Seaver, Xue-Ying He, Keith Abe, Tina Cowan, Gregory M Enns, Lawrence Sweetman, Manfred Philipp, Sansan Lee, Mazhar Malik, Song-Yu Yang. A novel mutation in the HSD17B10 gene of a 10-year-old boy with refractory epilepsy, choreoathetosis and learning disability.
PloS one.
2011; 6(11):e27348. doi:
10.1371/journal.pone.0027348. [PMID: 22132097] - Jennifer A Johnson, Kenneth L Le, Enrique Palacios. Propionic acidemia: case report and review of neurologic sequelae.
Pediatric neurology.
2009 Apr; 40(4):317-20. doi:
10.1016/j.pediatrneurol.2008.10.021. [PMID: 19302949] - Judit García-Villoria, Aleix Navarro-Sastre, Carme Fons, Celia Pérez-Cerdá, Antonio Baldellou, Miguel Angel Fuentes-Castelló, Inmaculada González, Arturo Hernández-Gonzalez, Cristina Fernández, Jaume Campistol, Carina Delpiccolo, Nuria Cortés, Angel Messeguer, Paz Briones, Antonia Ribes. Study of patients and carriers with 2-methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency: difficulties in the diagnosis.
Clinical biochemistry.
2009 Jan; 42(1-2):27-33. doi:
10.1016/j.clinbiochem.2008.10.006. [PMID: 18996107] - Lock Hock Ngu, Md Yunus Zabedah, Balasubramaniam Shanti, Siao Hean Teh. Biochemical profiling in two siblings with mitochondrial 2-methylacetoacetyl-CoA thiolase deficiency.
The Malaysian journal of pathology.
2008 Dec; 30(2):109-14. doi:
. [PMID: 19291920] - T Fukao, G X Zhang, N Sakura, T Kubo, H Yamaga, A Hazama, Y Kohno, N Matsuo, M Kondo, S Yamaguchi, Y Shigematsu, N Kondo. The mitochondrial acetoacetyl-CoA thiolase (T2) deficiency in Japanese patients: urinary organic acid and blood acylcarnitine profiles under stable conditions have subtle abnormalities in T2-deficient patients with some residual T2 activity.
Journal of inherited metabolic disease.
2003; 26(5):423-31. doi:
10.1023/a:1025117226051. [PMID: 14518824]
