2-(Dimethylamino)ethyl methacrylate (BioDeep_00000691648)
代谢物信息卡片
2-(N,N-Dimethylamino)ethyl methacrylate
化学式: C8H15NO2 (157.1103)
中文名称: 聚[甲基丙烯酸2-(二甲氨基)乙酯] (数均分子量25000), 甲基丙烯酸二甲氨基乙酯, 甲基丙烯酸2-（二甲氨基）乙酯
谱图信息:
最多检出来源 () %
分子结构信息
SMILES: CC(=C)C(=O)OCCN(C)C
InChI: InChI=1S/C8H15NO2/c1-7(2)8(10)11-6-5-9(3)4/h1,5-6H2,2-4H3
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D019163 - Reducing Agents
同义名列表
相关代谢途径
Reactome()
BioCyc()
PlantCyc()
代谢反应
个相关的代谢反应过程信息。
Reactome()
BioCyc()
WikiPathways()
Plant Reactome()
INOH()
PlantCyc()
COVID-19 Disease Map()
PathBank()
PharmGKB()
个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Kazunori Yamada, Asumi Takada, Ayako Konishi, Yuji Kimura, Hiromichi Asamoto, Hiroaki Minamisawa. Hexavalent Cr ion adsorption and desorption behaviour of expanded poly(tetrafluoro)ethylene films grafted with 2-(dimethylamino)ethyl methacrylate.
Environmental technology.
2021 May; 42(12):1885-1898. doi:
10.1080/09593330.2019.1683612. [PMID: 31631793] - Ylenia Miele, Anne-Françoise Mingotaud, Enrico Caruso, Miryam C Malacarne, Lorella Izzo, Barbara Lonetti, Federico Rossi. Hybrid giant lipid vesicles incorporating a PMMA-based copolymer.
Biochimica et biophysica acta. General subjects.
2021 04; 1865(4):129611. doi:
10.1016/j.bbagen.2020.129611. [PMID: 32272202] - Tengwen Zhao, Li Du, Ziyang Zhang, Na Li, Manman Wang, Qi Ren. A poly(N,N-dimethylaminoethyl methacrylate-co-ethylene glycol dimethacrylate) monolith for direct solid-phase extraction of benzodiazepines from undiluted human urine.
Analytical methods : advancing methods and applications.
2020 08; 12(31):3924-3932. doi:
10.1039/d0ay01025a. [PMID: 32720657] - Yubo Wei, Qiang Zeng, Jianzhi Huang, Xinrong Guo, Lulu Wang, Lishi Wang. Preparation of Gas-Responsive Imprinting Hydrogel and Their Gas-Driven Switchable Affinity for Target Protein Recognition.
ACS applied materials & interfaces.
2020 May; 12(21):24363-24369. doi:
10.1021/acsami.0c05561. [PMID: 32366087] - Annie K McClellan, Taisen Hao, Tracy A Brooks, Adam E Smith. RAFT Polymerization for the Synthesis of Tertiary Amine-Based Diblock Copolymer Nucleic Acid Delivery Vehicles.
Macromolecular bioscience.
2017 12; 17(12):. doi:
10.1002/mabi.201700225. [PMID: 29139616] - Yuji Pu, Zheng Hou, Mya Mya Khin, Rubi Zamudio-Vázquez, Kar Lai Poon, Hongwei Duan, Mary B Chan-Park. Synthesis and Antibacterial Study of Sulfobetaine/Quaternary Ammonium-Modified Star-Shaped Poly[2-(dimethylamino)ethyl methacrylate]-Based Copolymers with an Inorganic Core.
Biomacromolecules.
2017 01; 18(1):44-55. doi:
10.1021/acs.biomac.6b01279. [PMID: 28009508] - Bailiang Wang, Zi Ye, Yihong Tang, Yuemei Han, Quankui Lin, Huihua Liu, Hao Chen, Kaihui Nan. Fabrication of nonfouling, bactericidal, and bacteria corpse release multifunctional surface through surface-initiated RAFT polymerization.
International journal of nanomedicine.
2017 ; 12(?):111-125. doi:
10.2147/ijn.s107472. [PMID: 28053527] - Bailiang Wang, Zi Ye, Qingwen Xu, Huihua Liu, Quankui Lin, Hao Chen, Kaihui Nan. Construction of a temperature-responsive terpolymer coating with recyclable bactericidal and self-cleaning antimicrobial properties.
Biomaterials science.
2016 Nov; 4(12):1731-1741. doi:
10.1039/c6bm00587j. [PMID: 27782243] - Elena Benito-Peña, Victoria González-Vallejo, Alberto Rico-Yuste, Letricia Barbosa-Pereira, José Manuel Cruz, Ainhoa Bilbao, Carmen Alvarez-Lorenzo, María Cruz Moreno-Bondi. Molecularly imprinted hydrogels as functional active packaging materials.
Food chemistry.
2016 Jan; 190(?):487-494. doi:
10.1016/j.foodchem.2015.05.128. [PMID: 26213001] - Sung Han Kim, Jung Eun Lee, Shazid Md Sharker, Ji Hoon Jeong, Insik In, Sung Young Park. In Vitro and In Vivo Tumor Targeted Photothermal Cancer Therapy Using Functionalized Graphene Nanoparticles.
Biomacromolecules.
2015 Nov; 16(11):3519-29. doi:
10.1021/acs.biomac.5b00944. [PMID: 26451914] - Gunjan Bisht, M G H Zaidi. Supercritical synthesis of poly (2-dimethylaminoethyl methacrylate)/ferrite nanocomposites for real-time monitoring of protein release.
Drug delivery and translational research.
2015 Jun; 5(3):268-74. doi:
10.1007/s13346-015-0225-3. [PMID: 25809936] - N S Finiuk, A Ie Chaplia, N Ie Mitina, N M Boĭko, O V Lobachevs'ka, O S M'iahkota, A I Iemets', Ia B Blium, O S Zaichenko, R S Stoĭka. [Genetic transformation of the moss Ceratodon purpureus by novel polycationic carriers of DNA].
TSitologiia i genetika.
2014 Nov; 48(6):3-10. doi:
". [PMID: 25536816] - Ying Zhang, Qingsong Yu, Yong Wang. Non-thermal atmospheric plasmas in dental restoration: improved resin adhesive penetration.
Journal of dentistry.
2014 Aug; 42(8):1033-42. doi:
10.1016/j.jdent.2014.05.005. [PMID: 24859333] - Sanjay B Thorat, Alberto Diaspro, Marco Salerno. In vitro investigation of coupling-agent-free dental restorative composite based on nano-porous alumina fillers.
Journal of dentistry.
2014 Mar; 42(3):279-86. doi:
10.1016/j.jdent.2013.12.001. [PMID: 24333450] - Jong Woo Lee, Seonju Lee, Sangmok Jang, Kyu Young Han, Younggyu Kim, Jaekyung Hyun, Seong Keun Kim, Yan Lee. Preparation of non-aggregated fluorescent nanodiamonds (FNDs) by non-covalent coating with a block copolymer and proteins for enhancement of intracellular uptake.
Molecular bioSystems.
2013 May; 9(5):1004-11. doi:
10.1039/c2mb25431j. [PMID: 23364398] - Miao Wang, Jiang Yuan, Xiaobo Huang, Xianmei Cai, Li Li, Jian Shen. Grafting of carboxybetaine brush onto cellulose membranes via surface-initiated ARGET-ATRP for improving blood compatibility.
Colloids and surfaces. B, Biointerfaces.
2013 Mar; 103(?):52-8. doi:
10.1016/j.colsurfb.2012.10.025. [PMID: 23201719] - Tracey M Hinton, Carlos Guerrero-Sanchez, Janease E Graham, Tam Le, Benjamin W Muir, Shuning Shi, Mark L V Tizard, Pathiraja A Gunatillake, Keith M McLean, San H Thang. The effect of RAFT-derived cationic block copolymer structure on gene silencing efficiency.
Biomaterials.
2012 Oct; 33(30):7631-42. doi:
10.1016/j.biomaterials.2012.06.090. [PMID: 22831854] - David R Kryscio, Nicholas A Peppas. Surface imprinted thin polymer film systems with selective recognition for bovine serum albumin.
Analytica chimica acta.
2012 Mar; 718(?):109-15. doi:
10.1016/j.aca.2012.01.006. [PMID: 22305905] - Pieter Vader, Leonardus J van der Aa, Johan F J Engbersen, Gert Storm, Raymond M Schiffelers. Physicochemical and biological evaluation of siRNA polyplexes based on PEGylated Poly(amido amine)s.
Pharmaceutical research.
2012 Feb; 29(2):352-61. doi:
10.1007/s11095-011-0545-z. [PMID: 21833793] - Weiwei He, Lifen Zhang, Gaohua Zhu, Zhengbiao Zhang, Nianchen Zhou, Zhenping Cheng, Xiulin Zhu. Synthesis and properties of hydrogels prepared via AGET ATRP using iron salt as catalyst.
Journal of controlled release : official journal of the Controlled Release Society.
2011 Nov; 152 Suppl 1(?):e210-1. doi:
10.1016/j.jconrel.2011.09.014. [PMID: 22195860] - D Velasco, E Collin, J San Roman, A Pandit, C Elvira. End functionalized polymeric system derived from pyrrolidine provide high transfection efficiency.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2011 Nov; 79(3):485-94. doi:
10.1016/j.ejpb.2011.06.004. [PMID: 21723390] - Zhaoqiang Wu, Hong Chen, Dan Li, John L Brash. Tissue plasminogen activator-containing polyurethane surfaces for fibrinolytic activity.
Acta biomaterialia.
2011 May; 7(5):1993-8. doi:
10.1016/j.actbio.2011.01.026. [PMID: 21256990] - Joris P Schillemans, Ellen Verheyen, Arjan Barendregt, Wim E Hennink, Cornelus F Van Nostrum. Anionic and cationic dextran hydrogels for post-loading and release of proteins.
Journal of controlled release : official journal of the Controlled Release Society.
2011 Mar; 150(3):266-71. doi:
10.1016/j.jconrel.2010.11.027. [PMID: 21130815] - Fengying Dai, Wenguang Liu. Enhanced gene transfection and serum stability of polyplexes by PDMAEMA-polysulfobetaine diblock copolymers.
Biomaterials.
2011 Jan; 32(2):628-38. doi:
10.1016/j.biomaterials.2010.09.021. [PMID: 20888634] - Joris P Schillemans, Wim E Hennink, Cornelus F van Nostrum. The effect of network charge on the immobilization and release of proteins from chemically crosslinked dextran hydrogels.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2010 Nov; 76(3):329-35. doi:
10.1016/j.ejpb.2010.08.001. [PMID: 20708077] - Chun-li Zheng, Xiao-qing Liu, Jia-bi Zhu, Yu-na Zhao. [Preparation of cationic dextran microspheres loaded with tetanus toxoid and study on the mechanism of protein loading].
Yao xue xue bao = Acta pharmaceutica Sinica.
2010 Sep; 45(9):1183-7. doi:
. [PMID: 21351577] - Lee-Anne B Rawlinson, Peter J O'Brien, David J Brayden. High content analysis of cytotoxic effects of pDMAEMA on human intestinal epithelial and monocyte cultures.
Journal of controlled release : official journal of the Controlled Release Society.
2010 Aug; 146(1):84-92. doi:
10.1016/j.jconrel.2010.05.002. [PMID: 20457190] - J P Hervás Pérez, E López-Cabarcos, B López-Ruiz. Amperometric glucose biosensor based on biocompatible poly(dimethylaminoethyl) methacrylate microparticles.
Talanta.
2010 Jun; 81(4-5):1197-202. doi:
10.1016/j.talanta.2010.02.010. [PMID: 20441884] - Giuseppe Cirillo, Ortensia Ilaria Parisi, Manuela Curcio, Francesco Puoci, Francesca Iemma, Umile Gianfranco Spizzirri, Nevio Picci. Molecularly imprinted polymers as drug delivery systems for the sustained release of glycyrrhizic acid.
The Journal of pharmacy and pharmacology.
2010 May; 62(5):577-82. doi:
10.1211/jpp.62.05.0003. [PMID: 20609058] - Surachate Kalasin, Jeffrey Dabkowski, Klaus Nüsslein, Maria M Santore. The role of nano-scale heterogeneous electrostatic interactions in initial bacterial adhesion from flow: a case study with Staphylococcus aureus.
Colloids and surfaces. B, Biointerfaces.
2010 Apr; 76(2):489-95. doi:
10.1016/j.colsurfb.2009.12.009. [PMID: 20074917] - Won-Ho Kong, Dong-Kyung Sung, Yong-Ho Shim, Ki Hyun Bae, Philippe Dubois, Tae Gwan Park, Jin-Hoon Kim, Soo-Won Seo. Efficient intracellular siRNA delivery strategy through rapid and simple two steps mixing involving noncovalent post-PEGylation.
Journal of controlled release : official journal of the Controlled Release Society.
2009 Sep; 138(2):141-7. doi:
10.1016/j.jconrel.2009.04.034. [PMID: 19426771] - Chunmei Gao, Mingzhu Liu, Shilan Chen, Shuping Jin, Jun Chen. Preparation of oxidized sodium alginate-graft-poly((2-dimethylamino) ethyl methacrylate) gel beads and in vitro controlled release behavior of BSA.
International journal of pharmaceutics.
2009 Apr; 371(1-2):16-24. doi:
10.1016/j.ijpharm.2008.12.013. [PMID: 19135513] - Debra T Auguste, Kay Furman, Andrew Wong, Jason Fuller, Steven P Armes, Timothy J Deming, Robert Langer. Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes.
Journal of controlled release : official journal of the Controlled Release Society.
2008 Sep; 130(3):266-74. doi:
10.1016/j.jconrel.2008.06.004. [PMID: 18601962] - Wei Qin, Xue-Jun Cao. Synthesis of a novel pH-sensitive methacrylate amphiphilic polymer and its primary application in aqueous two-phase systems.
Applied biochemistry and biotechnology.
2008 Aug; 150(2):171-83. doi:
10.1007/s12010-008-8139-x. [PMID: 18597052] - Yan-Lei Su, Chao Li. The reorientation of poly(2-dimethylamino ethyl methacrylate) after environment stimuli improves hydrophilicity and resistance of protein adsorption.
Journal of colloid and interface science.
2007 Dec; 316(2):344-9. doi:
10.1016/j.jcis.2007.08.017. [PMID: 17825311] - Qiang Peng, Shiqiang Lu, Dezhi Chen, Xiaoqin Wu, Panfeng Fan, Rong Zhong, Yongwen Xu. Poly(vinylidene fluoride)-graft-poly(N-vinyl-2-pyrrolidone) copolymers prepared via a RAFT-mediated process and their use in antifouling and antibacterial membranes.
Macromolecular bioscience.
2007 Sep; 7(9-10):1149-59. doi:
10.1002/mabi.200700068. [PMID: 17705155] - Jouni Karppi, Satu Akerman, Kari Akerman, Annika Sundell, Kristiina Nyyssönen, Ilkka Penttilä. Adsorption of drugs onto a pH responsive poly(N,N-dimethyl aminoethyl methacrylate) grafted anion-exchange membrane in vitro.
International journal of pharmaceutics.
2007 Jun; 338(1-2):7-14. doi:
10.1016/j.ijpharm.2007.01.017. [PMID: 17289313] - Andy Kusumo, Lindsay Bombalski, Qiao Lin, Krzysztof Matyjaszewski, James W Schneider, Robert D Tilton. High capacity, charge-selective protein uptake by polyelectrolyte brushes.
Langmuir : the ACS journal of surfaces and colloids.
2007 Apr; 23(8):4448-54. doi:
10.1021/la063660b. [PMID: 17358090] - Irina N Savina, Igor Yu Galaev, Bo Mattiasson. Ion-exchange macroporous hydrophilic gel monolith with grafted polymer brushes.
Journal of molecular recognition : JMR.
2006 Jul; 19(4):313-21. doi:
10.1002/jmr.774. [PMID: 16703569] - Sophie R Van Tomme, Bruno G De Geest, Kevin Braeckmans, Stefaan C De Smedt, Florence Siepmann, Juergen Siepmann, Cornelus F van Nostrum, Wim E Hennink. Mobility of model proteins in hydrogels composed of oppositely charged dextran microspheres studied by protein release and fluorescence recovery after photobleaching.
Journal of controlled release : official journal of the Controlled Release Society.
2005 Dec; 110(1):67-78. doi:
10.1016/j.jconrel.2005.09.005. [PMID: 16253375] - Zhiyuan Zhong, Yan Song, Johan F J Engbersen, Martin C Lok, Wim E Hennink, Jan Feijen. A versatile family of degradable non-viral gene carriers based on hyperbranched poly(ester amine)s.
Journal of controlled release : official journal of the Controlled Release Society.
2005 Dec; 109(1-3):317-29. doi:
10.1016/j.jconrel.2005.06.022. [PMID: 16081184] - Joan E Sanders, Sarah E Lamont, Ari Karchin, Steven L Golledge, Buddy D Ratner. Fibro-porous meshes made from polyurethane micro-fibers: effects of surface charge on tissue response.
Biomaterials.
2005 Mar; 26(7):813-8. doi:
10.1016/j.biomaterials.2004.03.030. [PMID: 15350787] - M van der Aa, G Koning, J van der Gugten, C d'Oliveira, R Oosting, W E Hennink, D J A Crommelin. Covalent attachment of an NLS-peptide to linear dna does not enhance transfection efficiency of cationic polymer based gene delivery systems.
Journal of controlled release : official journal of the Controlled Release Society.
2005 Jan; 101(1-3):395-7. doi:
NULL. [PMID: 15822233] - Sabine Pirotton, Caroline Muller, Nadège Pantoustier, François Botteman, Sébastien Collinet, Christian Grandfils, Guy Dandrifosse, Philippe Degée, Philippe Dubois, Martine Raes. Enhancement of transfection efficiency through rapid and noncovalent post-PEGylation of poly(dimethylaminoethyl methacrylate)/DNA complexes.
Pharmaceutical research.
2004 Aug; 21(8):1471-9. doi:
10.1023/b:pham.0000036923.25772.97. [PMID: 15359584] - Zhi-Kang Xu, Qing-Wen Dai, Jian Wu, Xiao-Jun Huang, Qian Yang. Covalent attachment of phospholipid analogous polymers to modify a polymeric membrane surface: a novel approach.
Langmuir : the ACS journal of surfaces and colloids.
2004 Feb; 20(4):1481-8. doi:
10.1021/la035930l. [PMID: 15803738] - Ferry Verbaan, Inger van Dam, Yoshinubu Takakura, Mitsuru Hashida, Wim Hennink, Gert Storm, Christien Oussoren. Intravenous fate of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2003 Dec; 20(4-5):419-27. doi:
10.1016/j.ejps.2003.09.005. [PMID: 14659486] - Elena Loizou, Aggeliki I Triftaridou, Theoni K Georgiou, Maria Vamvakaki, Costas S Patrickios. Cationic double-hydrophilic model networks: synthesis, characterization, modeling and protein adsorption studies.
Biomacromolecules.
2003 Sep; 4(5):1150-60. doi:
10.1021/bm020102c. [PMID: 12959578] - J E Sanders, D V Cassisi, T Neumann, S L Golledge, S G Zachariah, B D Ratner, S D Bale. Relative influence of polymer fiber diameter and surface charge on fibrous capsule thickness and vessel density for single-fiber implants.
Journal of biomedical materials research. Part A.
2003 Jun; 65(4):462-7. doi:
10.1002/jbm.a.10525. [PMID: 12761836] - Carol A Lapp, George S Schuster. Effects of DMAEMA and 4-methoxyphenol on gingival fibroblast growth, metabolism, and response to interleukin-1.
Journal of biomedical materials research.
2002 Apr; 60(1):30-5. doi:
10.1002/jbm.10057. [PMID: 11835156] - Elisabeth Moreau, Martine Domurado, Pascal Chapon, Michel Vert, Dominique Domurad. Biocompatibility of polycations: in vitro agglutination and lysis of red blood cells and in vivo toxicity.
Journal of drug targeting.
2002 Mar; 10(2):161-73. doi:
10.1080/10611860290016766. [PMID: 12074543] - Ayşe Gönen Karakeçili, Menemşe Gümüşderelioglu. Comparison of bacterial and tissue cell initial adhesion on hydrophilic/hydrophobic biomaterials.
Journal of biomaterials science. Polymer edition.
2002; 13(2):185-96. doi:
10.1163/156856202317414366. [PMID: 12022749] - E Mastrobattista, R H Kapel, M H Eggenhuisen, P J Roholl, D J Crommelin, W E Hennink, G Storm. Lipid-coated polyplexes for targeted gene delivery to ovarian carcinoma cells.
Cancer gene therapy.
2001 Jun; 8(6):405-13. doi:
10.1038/sj.cgt.7700311. [PMID: 11498760] - F J Verbaan, C Oussoren, I M van Dam, Y Takakura, M Hashida, D J Crommelin, W E Hennink, G Storm. The fate of poly(2-dimethyl amino ethyl)methacrylate-based polyplexes after intravenous administration.
International journal of pharmaceutics.
2001 Feb; 214(1-2):99-101. doi:
10.1016/s0378-5173(00)00642-6. [PMID: 11282245] - G B Caughman, G S Schuster, F A Rueggeberg. Cell lipid alterations resulting from prolonged exposure to dimethylaminoethylmethacrylate.
Clinical oral investigations.
1999 Dec; 3(4):181-7. doi:
10.1007/s007840050099. [PMID: 10803132] - B Zhu, H Iwata, D Kong, Y Yu, K Kato, Y Ikada. Preparation of DNA-immobilized immunoadsorbent for treatment of systemic lupus erythematosus.
Journal of biomaterials science. Polymer edition.
1999; 10(3):341-50. doi:
10.1163/156856299x00405. [PMID: 10189102] - A Yousefi Rad, H Ayhan, U Kisa, E Pişkin. Adhesion of different bacterial strains to low-temperature plasma treated biomedical PVC catheter surfaces.
Journal of biomaterials science. Polymer edition.
1998; 9(9):915-29. doi:
10.1163/156856298x00244. [PMID: 9747985] - G S Schuster, J F Erbland, C A Lefebvre, G B Caughman, K L Knoernschild. Effects of an aminomethacrylate on epithelial cell lipid metabolism.
Journal of biomaterials science. Polymer edition.
1997; 8(5):363-75. doi:
10.1163/156856297x00155. [PMID: 9105976] - S Fujisawa, Y Kadoma, E Masuhara. Effects of photoinitiators for the visible-light resin system on hemolysis of dog erythrocytes and lipid peroxidation of their components.
Journal of dental research.
1986 Sep; 65(9):1186-90. doi:
10.1177/00220345860650091401. [PMID: 3461034] - A C Buck. Disorders of micturition in bacterial prostatitis.
Proceedings of the Royal Society of Medicine.
1975 Aug; 68(8):508-11. doi:
NULL. [PMID: 681]
