24, 25-Dihydroxy VD3 (BioDeep_00000173723)
Main id: BioDeep_00000006580
human metabolite blood metabolite
代谢物信息卡片
6-{4-[2-(5-hydroxy-2-methylidenecyclohexylidene)ethylidene]-7a-methyl-octahydro-1H-inden-1-yl}-2-methylheptane-2,3-diol
化学式: C27H44O3 (416.329)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C=C1CC[C@@H](C/C/1=C/C=C/1\CCC[C@]2(C)[C@H](CC[C@@H]12)[C@H](C)CC[C@H](C(C)(C)O)O)O
InChI: InChI=1S/C27H44O3/c1-18-8-12-22(28)17-21(18)11-10-20-7-6-16-27(5)23(13-14-24(20)27)19(2)9-15-25(29)26(3,4)30/h10-11,19,22-25,28-30H,1,6-9,12-17H2,2-5H3
描述信息
同义名列表
14 个代谢物同义名
6-{4-[2-(5-hydroxy-2-methylidenecyclohexylidene)ethylidene]-7a-methyl-octahydro-1H-inden-1-yl}-2-methylheptane-2,3-diol; 6-{4-[2-(5-hydroxy-2-methylidenecyclohexylidene)ethylidene]-7a-methyl-hexahydro-1H-inden-1-yl}-2-methylheptane-2,3-diol; 24,25-Dihydroxyvitamin D 3, (3beta,5Z,7E,24R)-isomer; 24R,25 Dihydroxycholecalciferol; (24R)-24,25-Dihydroxyvitamin D3; 24R,25-Dihydroxycholecalciferol; 24,25 Dihydroxycholecalciferol; 24,25-Dihydroxycholecalciferol; 24,25 Dihydroxyvitamin D 3; Dihydroxyvitamin D3, 24,25; 24,25-Dihydroxyvitamin D 3; 24,25-Dihydroxyvitamin D3; 24,25 Dihydroxyvitamin D3; 24, 25-Dihydroxy VD3
数据库引用编号
5 个数据库交叉引用编号
- PubChem: 1590
- HMDB: HMDB0245662
- chemspider: 1532
- RefMet: 24,25-Dihydroxyvitamin D3
- PubChem: 5283748
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Anastasia Alexandridou, Dietrich A Volmer. 2-fluoro-1-methylpyridinium p-toluene sulfonate: a new LC-MS/MS derivatization reagent for vitamin D metabolites.
Journal of lipid research.
2023 08; 64(8):100409. doi:
10.1016/j.jlr.2023.100409. [PMID: 37406930] - Simon Hsu, Leila R Zelnick, Yvonne S Lin, Cora M Best, Bryan R Kestenbaum, Kenneth E Thummel, Andrew N Hoofnagle, Ian H de Boer. Validation of the 24,25-dihydroxyvitamin D3 to 25-hydroxyvitamin D3 ratio as a biomarker of 25-hydroxyvitamin D3 clearance.
The Journal of steroid biochemistry and molecular biology.
2022 03; 217(?):106047. doi:
10.1016/j.jsbmb.2021.106047. [PMID: 34954017] - Sieglinde Zelzer, Caroline Le Goff, Stéphanie Peeters, Chiara Calaprice, Andreas Meinitzer, Dietmar Enko, Walter Goessler, Markus Herrmann, Etienne Cavalier. Comparison of two LC-MS/MS methods for the quantification of 24,25-dihydroxyvitamin D3 in patients and external quality assurance samples.
Clinical chemistry and laboratory medicine.
2022 01; 60(1):74-81. doi:
10.1515/cclm-2021-0792. [PMID: 34727586] - Dae-Hyun Ko, Sun-Hee Jun, Youngwon Nam, Sang H Song, Minje Han, Yeo-Min Yun, Kyunghoon Lee, Junghan Song. Multiplex LC-MS/MS for simultaneous determination of 25-hydroxyvitamin D, 24,25-dihydroxyvitamin D3, albumin, and vitamin D-binding protein with its isoforms: One-step estimation of bioavailable vitamin D and vitamin D metabolite ratio.
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2021 02; 206(?):105796. doi:
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Nutrients.
2020 Dec; 12(12):. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
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10.1016/j.jchromb.2020.122394. [PMID: 33091679] - Anna E Goodroe, Casey Fitz, Michael L Power, Ricki J Colman, Saverio Capuano, Toni E Ziegler. Evaluation of vitamin D3 metabolites in Callithrix jacchus (common marmoset).
American journal of primatology.
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Clinical chemistry and laboratory medicine.
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The Journal of steroid biochemistry and molecular biology.
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Clinical and experimental nephrology.
2019 Oct; 23(10):1202-1210. doi:
10.1007/s10157-019-01760-3. [PMID: 31240503] - Anjali Verma, D Joshua Cohen, Nofrat Schwartz, Chandana Muktipaty, Jennifer E Koblinski, Barbara D Boyan, Zvi Schwartz. 24R,25-Dihydroxyvitamin D3 regulates breast cancer cells in vitro and in vivo.
Biochimica et biophysica acta. General subjects.
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Steroids.
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The Journal of clinical endocrinology and metabolism.
2018 09; 103(9):3368-3375. doi:
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International journal of molecular sciences.
2018 07; 19(7):. doi:
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Clinical nutrition (Edinburgh, Scotland).
2018 06; 37(3):1041-1045. doi:
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The Journal of nutritional biochemistry.
2018 06; 56(?):65-73. doi:
10.1016/j.jnutbio.2018.01.011. [PMID: 29459310] - Anouk M M Vaes, Michael Tieland, Margot F de Regt, Jonas Wittwer, Luc J C van Loon, Lisette C P G M de Groot. Dose-response effects of supplementation with calcifediol on serum 25-hydroxyvitamin D status and its metabolites: A randomized controlled trial in older adults.
Clinical nutrition (Edinburgh, Scotland).
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Bone.
2018 05; 110(?):321-325. doi:
10.1016/j.bone.2018.02.024. [PMID: 29486367] - Robin Taylor Wilson, Loren D Masters, Jill S Barnholtz-Sloan, Anna C Salzberg, Terryl J Hartman. Ancestry-Adjusted Vitamin D Metabolite Concentrations in Association With Cytochrome P450 3A Polymorphisms.
American journal of epidemiology.
2018 04; 187(4):754-766. doi:
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Journal of AOAC International.
2017 Sep; 100(5):1308-1317. doi:
10.5740/jaoacint.17-0183. [PMID: 28741469] - Martin Kaufmann, Nicole Morse, Billy Joe Molloy, Donald P Cooper, Karl Peter Schlingmann, Arnaud Molin, Marie Laure Kottler, J Christopher Gallagher, Laura Armas, Glenville Jones. Improved Screening Test for Idiopathic Infantile Hypercalcemia Confirms Residual Levels of Serum 24,25-(OH)2 D3 in Affected Patients.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
2017 Jul; 32(7):1589-1596. doi:
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Medicine and science in sports and exercise.
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Analytical and bioanalytical chemistry.
2016 Nov; 408(27):7617-7627. doi:
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American journal of kidney diseases : the official journal of the National Kidney Foundation.
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American journal of kidney diseases : the official journal of the National Kidney Foundation.
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The American journal of clinical nutrition.
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Clinical endocrinology.
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