Fluoroacetaldehyde (BioDeep_00000010741)

 

Secondary id: BioDeep_00001872236

human metabolite blood metabolite


代谢物信息卡片


2-fluoroacetaldehyde

化学式: C2H3FO (62.0168)
中文名称: 氟乙醛
谱图信息: 最多检出来源 Homo sapiens(blood) 56.1%

分子结构信息

SMILES: C(C=O)F
InChI: InChI=1S/C2H3FO/c3-1-2-4/h2H,1H2

描述信息

同义名列表

2 个代谢物同义名

2-fluoroacetaldehyde; Fluoroacetaldehyde



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

5 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(3)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Robert Mintzer, Sreemathy Ramaswamy, Kinjalkumar Shah, Rami N Hannoush, Christine D Pozniak, Frederick Cohen, Xianrui Zhao, Emile Plise, Joseph W Lewcock, Christopher E Heise. A whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/C. PloS one. 2012; 7(1):e30376. doi: 10.1371/journal.pone.0030376. [PMID: 22253931]
  • Carmela Fimognari, Monia Lenzi, Lorenzo Ferruzzi, Eleonora Turrini, Paolo Scartezzini, Ferruccio Poli, Roberto Gotti, Alessandra Guerrini, Giovanni Carulli, Virginia Ottaviano, Giorgio Cantelli-Forti, Patrizia Hrelia. Mitochondrial pathway mediates the antileukemic effects of Hemidesmus indicus, a promising botanical drug. PloS one. 2011; 6(6):e21544. doi: 10.1371/journal.pone.0021544. [PMID: 21738701]
  • Maqsood Yaqub, Ronald Boellaard, Bart N M van Berckel, Nelleke Tolboom, Gert Luurtsema, Anke A Dijkstra, Mark Lubberink, Albert D Windhorst, Philip Scheltens, Adriaan A Lammertsma. Evaluation of tracer kinetic models for analysis of [18F]FDDNP studies. Molecular imaging and biology. 2009 Sep; 11(5):322-33. doi: 10.1007/s11307-009-0208-1. [PMID: 19340487]
  • Thomas Kessler, H Arno J Müller. Cleavage of Armadillo/beta-catenin by the caspase DrICE in Drosophila apoptotic epithelial cells. BMC developmental biology. 2009 Feb; 9(?):15. doi: 10.1186/1471-213x-9-15. [PMID: 19232093]
  • Peter Weber, Ping Wang, Stephane Maddens, Paul Sh Wang, Rongqian Wu, Michael Miksa, Weifeng Dong, Michael Mortimore, Julian M C Golec, Peter Charlton. VX-166: a novel potent small molecule caspase inhibitor as a potential therapy for sepsis. Critical care (London, England). 2009; 13(5):R146. doi: 10.1186/cc8041. [PMID: 19740426]
  • Chen-Li Liu, Li-Xia Xie, Min Li, Siva Sundara Kumar Durairajan, Shinya Goto, Jian-Dong Huang. Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling. PloS one. 2007 Dec; 2(12):e1321. doi: 10.1371/journal.pone.0001321. [PMID: 18091994]
  • J Rozman-Pungercar, N Kopitar-Jerala, M Bogyo, D Turk, O Vasiljeva, I Stefe, P Vandenabeele, D Brömme, V Puizdar, M Fonović, M Trstenjak-Prebanda, I Dolenc, V Turk, B Turk. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell death and differentiation. 2003 Aug; 10(8):881-8. doi: 10.1038/sj.cdd.4401247. [PMID: 12867995]
  • Cormac D Murphy, Christoph Schaffrath, David O'Hagan. Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya. Chemosphere. 2003 Jul; 52(2):455-61. doi: 10.1016/s0045-6535(03)00191-7. [PMID: 12738270]
  • L Lemaire, M C Malet-Martino, M de Forni, R Martino, B Lasserre. Cardiotoxicity of commercial 5-fluorouracil vials stems from the alkaline hydrolysis of this drug. British journal of cancer. 1992 Jul; 66(1):119-27. doi: 10.1038/bjc.1992.227. [PMID: 1637660]