Lucidin (BioDeep_00000008051)

Main id: BioDeep_00000229860

 

PANOMIX_OTCML-2023


代谢物信息卡片


Lucidin

化学式: C15H10O5 (270.052821)
中文名称: 芦西定
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=O)C3=CC(=C(C(=C3C2=O)O)CO)O
InChI: InChI=1S/C15H10O5/c16-6-10-11(17)5-9-12(15(10)20)14(19)8-4-2-1-3-7(8)13(9)18/h1-5,16-17,20H,6H2

描述信息

Lucidin (NSC 30546) is a natural component of madder and can induce mutations in bacterial and mammalian cells.
Lucidin (NSC 30546) is a natural component of madder and can induce mutations in bacterial and mammalian cells.

同义名列表

2 个代谢物同义名

Lucidin; NSC 30546



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

38 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuxiao Yao, Shaoyang Sun, Fei Fei, Jingjing Wang, Youhua Wang, Ranran Zhang, Jing Wu, Lian Liu, Xiuyun Liu, Zhaomeng Cui, Qiang Li, Min Yu, Yongjun Dang, Xu Wang. Screening in larval zebrafish reveals tissue-specific distribution of fifteen fluorescent compounds. Disease models & mechanisms. 2017 09; 10(9):1155-1164. doi: 10.1242/dmm.028811. [PMID: 28754836]
  • Lauren Ford, Christopher M Rayner, Richard S Blackburn. Isolation and extraction of ruberythric acid from Rubia tinctorum L. and crystal structure elucidation. Phytochemistry. 2015 Sep; 117(?):168-173. doi: 10.1016/j.phytochem.2015.06.015. [PMID: 26091962]
  • Robert L Henderson, Christopher M Rayner, Richard S Blackburn. Isolation and extraction of lucidin primeveroside from Rubia tinctorum L. and crystal structure elucidation. Phytochemistry. 2013 Nov; 95(?):105-8. doi: 10.1016/j.phytochem.2013.07.001. [PMID: 23891215]
  • Yuji Ishii, Kaoru Inoue, Shinji Takasu, Meilan Jin, Kohei Matsushita, Ken Kuroda, Kiyoshi Fukuhara, Akiyoshi Nishikawa, Takashi Umemura. Determination of lucidin-specific DNA adducts by liquid chromatography with tandem mass spectrometry in the livers and kidneys of rats given lucidin-3-O-primeveroside. Chemical research in toxicology. 2012 May; 25(5):1112-8. doi: 10.1021/tx300084p. [PMID: 22494063]
  • Chen-Chen Wu, Xiao-Bing Li, Tie-Suo Han, Peng Li, Guo-Wen Liu, Wei-Zhong Wang, Zhe Wang. Dietary pseudopurpurin effects on bone mineral density and bone geometry architecture in rats. International journal of molecular sciences. 2012; 13(3):3431-3443. doi: 10.3390/ijms13033431. [PMID: 22489160]
  • Feng Zhao, Sujuan Wang, Xiuli Wu, Yang Yu, Zhenggang Yue, Bo Liu, Sheng Lin, Chenggen Zhu, Yongchun Yang, Jiangong Shi. [Anthraquinones from the roots of Knoxia valerianoides]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Nov; 36(21):2980-6. doi: . [PMID: 22308688]
  • Nam Hee Yoo, Dae Sik Jang, Yun Mi Lee, Il Ha Jeong, Jung-Hee Cho, Joo-Hwan Kim, Jin Sook Kim. Anthraquinones from the roots of Knoxia valerianoides inhibit the formation of advanced glycation end products and rat lens aldose reductase in vitro. Archives of pharmacal research. 2010 Feb; 33(2):209-14. doi: 10.1007/s12272-010-0204-7. [PMID: 20195820]
  • Yuji Ishii, Toshiya Okamura, Tomoki Inoue, Kiyoshi Fukuhara, Takashi Umemura, Akiyoshi Nishikawa. Chemical structure determination of DNA bases modified by active metabolites of lucidin-3-O-primeveroside. Chemical research in toxicology. 2010 Jan; 23(1):134-41. doi: 10.1021/tx900314c. [PMID: 20000472]
  • Kaoru Inoue, Midori Yoshida, Miwa Takahashi, Hitoshi Fujimoto, Kuniyoshi Ohnishi, Koichi Nakashima, Makoto Shibutani, Masao Hirose, Akiyoshi Nishikawa. Possible contribution of rubiadin, a metabolite of madder color, to renal carcinogenesis in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2009 Apr; 47(4):752-9. doi: 10.1016/j.fct.2009.01.003. [PMID: 19167447]
  • Wei Xiang, Qi-Shi Song, Hong-Jie Zhang, Shi-Ping Guo. Antimicrobial anthraquinones from Morinda angustifolia. Fitoterapia. 2008 Dec; 79(7-8):501-4. doi: 10.1016/j.fitote.2008.04.008. [PMID: 18621113]
  • Kohei Kamiya, Wakako Hamabe, Sachiko Harada, Rie Murakami, Shogo Tokuyama, Toshiko Satake. Chemical constituents of Morinda citrifolia roots exhibit hypoglycemic effects in streptozotocin-induced diabetic mice. Biological & pharmaceutical bulletin. 2008 May; 31(5):935-8. doi: 10.1248/bpb.31.935. [PMID: 18451522]
  • I Boldizsár, Z Szucs, Zs Füzfai, I Molnár-Perl. Identification and quantification of the constituents of madder root by gas chromatography and high-performance liquid chromatography. Journal of chromatography. A. 2006 Nov; 1133(1-2):259-74. doi: 10.1016/j.chroma.2006.08.021. [PMID: 16962601]
  • Fumi Nakanishi, Yuki Nagasawa, Yumi Kabaya, Hiroyuki Sekimoto, Koichiro Shimomura. Characterization of lucidin formation in Rubia tinctorum L. Plant physiology and biochemistry : PPB. 2005 Oct; 43(10-11):921-8. doi: 10.1016/j.plaphy.2005.08.005. [PMID: 16310368]
  • Imre Boldizsár, Abel László-Bencsik, Zoltán Szucs, Béla Dános. [Examination of the anthraquinone composition in root-stock and root samples of Rubia tinctorium L. plants of different origins]. Acta pharmaceutica Hungarica. 2004; 74(3):142-8. doi: ". [PMID: 16318223]
  • Goverdina C H Derksen, Martijn Naayer, Teris A van Beek, Anthony Capelle, Ingrid K Haaksman, Henk A van Doren, Aede de Groot. Chemical and enzymatic hydrolysis of anthraquinone glycosides from madder roots. Phytochemical analysis : PCA. 2003 May; 14(3):137-44. doi: 10.1002/pca.694. [PMID: 12793459]
  • F Marec, I Kollárová, A Jegorov. Mutagenicity of natural anthraquinones from Rubia tinctorum in the Drosophila wing spot test. Planta medica. 2001 Mar; 67(2):127-31. doi: 10.1055/s-2001-11498. [PMID: 11301857]
  • Y Kawasaki, Y Goda, H Noguchi, T Yamada. Identification of adducts formed by reaction of purine bases with a mutagenic anthraquinone, lucidin: mechanism of mutagenicity by anthraquinones occurring in rubiaceae plants. Chemical & pharmaceutical bulletin. 1994 Sep; 42(9):1971-3. doi: 10.1248/cpb.42.1971. [PMID: 7954947]
  • B Blömeke, B Poginsky, C Schmutte, H Marquardt, J Westendorf. Formation of genotoxic metabolites from anthraquinone glycosides, present in Rubia tinctorum L. Mutation research. 1992 Feb; 265(2):263-72. doi: 10.1016/0027-5107(92)90055-7. [PMID: 1370725]
  • B Poginsky, J Westendorf, B Blömeke, H Marquardt, A Hewer, P L Grover, D H Phillips. Evaluation of DNA-binding activity of hydroxyanthraquinones occurring in Rubia tinctorum L. Carcinogenesis. 1991 Jul; 12(7):1265-71. doi: 10.1093/carcin/12.7.1265. [PMID: 2070492]
  • Y Yasui, N Takeda. Identification of a mutagenic substance, in Rubia tinctorum L. (madder) root, as lucidin. Mutation research. 1983 Sep; 121(3-4):185-90. doi: 10.1016/0165-7992(83)90201-4. [PMID: 6621581]