Ent-Catechin (BioDeep_00000621566)
Main id: BioDeep_00000395874
PANOMIX_OTCML-2023
代谢物信息卡片
(2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
化学式: C15H14O6 (290.0790344)
中文名称: (-)-儿茶素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O
InChI: InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m1/s1
描述信息
(-)-Catechin is an isomer of Catechin having a trans 2S,3R configuration at the chiral center. Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
(-)-Catechin is an isomer of Catechin having a trans 2S,3R configuration at the chiral center. Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
(-)-Catechin is an isomer of Catechin having a trans 2S,3R configuration at the chiral center. Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
(-)-Catechin is an isomer of Catechin having a trans 2S,3R configuration at the chiral center. Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:33992
- PubChem: 73160
- Metlin: METLIN92745
- ChEMBL: CHEMBL200715
- CAS: 18829-70-4
- KEGG: C14079
- PubChem: 854316
- KNApSAcK: C00008808
- PDB-CCD: M5O
- NIKKAJI: J21.708E
- medchemexpress: HY-N0898A
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
4 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lun K Tsou, Jacob S Yount, Howard C Hang. Epigallocatechin-3-gallate inhibits bacterial virulence and invasion of host cells.
Bioorganic & medicinal chemistry.
2017 06; 25(11):2883-2887. doi:
10.1016/j.bmc.2017.03.023. [PMID: 28325635] - Keisuke Tomohara, Tomohiro Ito, Saika Onikata, Atsushi Kato, Isao Adachi. Discovery of hyaluronidase inhibitors from natural products and their mechanistic characterization under DMSO-perturbed assay conditions.
Bioorganic & medicinal chemistry letters.
2017 04; 27(7):1620-1623. doi:
10.1016/j.bmcl.2017.01.083. [PMID: 28202328] - Jong Hoon Ahn, Eun Sil Kim, Chul Lee, Soonok Kim, Soo-Hyun Cho, Bang Yeon Hwang, Mi Kyeong Lee. Chemical constituents from Nelumbo nucifera leaves and their anti-obesity effects.
Bioorganic & medicinal chemistry letters.
2013 Jun; 23(12):3604-8. doi:
10.1016/j.bmcl.2013.04.013. [PMID: 23642481] - Yongzhen Pang, I Sarath B Abeysinghe, Ji He, Xianzhi He, David Huhman, K Mudith Mewan, Lloyd W Sumner, Jianfei Yun, Richard A Dixon. Functional characterization of proanthocyanidin pathway enzymes from tea and their application for metabolic engineering.
Plant physiology.
2013 Mar; 161(3):1103-16. doi:
10.1104/pp.112.212050. [PMID: 23288883] - Jie Yin, Eleonora Miquel Becker, Mogens L Andersen, Leif H Skibsted. Green tea extract as food antioxidant. Synergism and antagonism with α-tocopherol in vegetable oils and their colloidal systems.
Food chemistry.
2012 Dec; 135(4):2195-202. doi:
10.1016/j.foodchem.2012.07.025. [PMID: 22980790] - Jeppe S Schmidt, Michael B Lauridsen, Lars O Dragsted, John Nielsen, Dan Staerk. Development of a bioassay-coupled HPLC-SPE-ttNMR platform for identification of α-glucosidase inhibitors in apple peel (Malus ×domestica Borkh.).
Food chemistry.
2012 Dec; 135(3):1692-9. doi:
10.1016/j.foodchem.2012.05.075. [PMID: 22953911] - M Colon, C Nerin. Role of catechins in the antioxidant capacity of an active film containing green tea, green coffee, and grapefruit extracts.
Journal of agricultural and food chemistry.
2012 Oct; 60(39):9842-9. doi:
10.1021/jf302477y. [PMID: 22973940] - Danhui Li, Nataly Martini, Zimei Wu, Jingyuan Wen. Development of an isocratic HPLC method for catechin quantification and its application to formulation studies.
Fitoterapia.
2012 Oct; 83(7):1267-74. doi:
10.1016/j.fitote.2012.06.006. [PMID: 22735602] - Claudia Velázquez, José Correa-Basurto, Normand Garcia-Hernandez, Elizabeth Barbosa, Emiliano Tesoro-Cruz, Samuel Calzada, Fernando Calzada. Anti-diarrheal activity of (-)-epicatechin from Chiranthodendron pentadactylon Larreat: experimental and computational studies.
Journal of ethnopharmacology.
2012 Sep; 143(2):716-9. doi:
10.1016/j.jep.2012.07.039. [PMID: 22884870] - Deng-Jye Yang, Yan-Zin Chang, Yi-Chen Chen, Shih-Chuan Liu, Chuan-Hsiang Hsu, Jau-Tien Lin. Antioxidant effect and active components of litchi (Litchi chinensis Sonn.) flower.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Sep; 50(9):3056-61. doi:
10.1016/j.fct.2012.06.011. [PMID: 22721981] - Lucas Actis-Goretta, Antoine Lévèques, Francesca Giuffrida, Fedor Romanov-Michailidis, Florian Viton, Denis Barron, Montserrat Duenas-Paton, Susana Gonzalez-Manzano, Celestino Santos-Buelga, Gary Williamson, Fabiola Dionisi. Elucidation of (-)-epicatechin metabolites after ingestion of chocolate by healthy humans.
Free radical biology & medicine.
2012 Aug; 53(4):787-95. doi:
10.1016/j.freeradbiomed.2012.05.023. [PMID: 22664313] - Fedor Romanov-Michailidis, Florian Viton, René Fumeaux, Antoine Lévèques, Lucas Actis-Goretta, Maarit Rein, Gary Williamson, Denis Barron. Epicatechin B-ring conjugates: first enantioselective synthesis and evidence for their occurrence in human biological fluids.
Organic letters.
2012 Aug; 14(15):3902-5. doi:
10.1021/ol3016463. [PMID: 22799566] - Tianli Yue, Dongyan Shao, Yahong Yuan, Zhouli Wang, Chunyan Qiang. Ultrasound-assisted extraction, HPLC analysis, and antioxidant activity of polyphenols from unripe apple.
Journal of separation science.
2012 Aug; 35(16):2138-45. doi:
10.1002/jssc.201200295. [PMID: 22815261] - Monika A Papiez, Karolina Bukowska-Straková, Wirginia Krzysciak, Jaroslaw Baran. (-)-Epicatechin enhances etoposide-induced antileukaemic effect in rats with acute myeloid leukaemia.
Anticancer research.
2012 Jul; 32(7):2905-13. doi:
. [PMID: 22753754] - Liubin Wei, Jinman Chen, Wencai Ye, Guangxiong Zhou. [Chemical constituents contained in roots of Pterospermum heterophyllum].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2012 Jul; 37(13):1981-4. doi:
10.4268/cjcmm20121325. [PMID: 23019883] - S Saha, W Hollands, P W Needs, L M Ostertag, B de Roos, G G Duthie, P A Kroon. Human O-sulfated metabolites of (-)-epicatechin and methyl-(-)-epicatechin are poor substrates for commercial aryl-sulfatases: implications for studies concerned with quantifying epicatechin bioavailability.
Pharmacological research.
2012 Jun; 65(6):592-602. doi:
10.1016/j.phrs.2012.02.005. [PMID: 22373658] - Adéline Delcambre, Cédric Saucier. Identification of new flavan-3-ol monoglycosides by UHPLC-ESI-Q-TOF in grapes and wine.
Journal of mass spectrometry : JMS.
2012 Jun; 47(6):727-36. doi:
10.1002/jms.3007. [PMID: 22707165] - Koneni V Sashidhara, Suriya P Singh, Sweta Misra, Jyoti Gupta, Shailja Misra-Bhattacharya. Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic filarial parasite, Brugia malayi.
European journal of medicinal chemistry.
2012 Apr; 50(?):230-5. doi:
10.1016/j.ejmech.2012.01.057. [PMID: 22348826] - Maria Nikolantonaki, Michael Jourdes, Kentaro Shinoda, Pierre-Louis Teissedre, Stéphane Quideau, Philippe Darriet. Identification of adducts between an odoriferous volatile thiol and oxidized grape phenolic compounds: kinetic study of adduct formation under chemical and enzymatic oxidation conditions.
Journal of agricultural and food chemistry.
2012 Mar; 60(10):2647-56. doi:
10.1021/jf204295s. [PMID: 22324817] - Judith C W Mak. Potential role of green tea catechins in various disease therapies: progress and promise.
Clinical and experimental pharmacology & physiology.
2012 Mar; 39(3):265-73. doi:
10.1111/j.1440-1681.2012.05673.x. [PMID: 22229384] - Yung-Fen Huang, Agnès Doligez, Alexandre Fournier-Level, Loïc Le Cunff, Yves Bertrand, Aurélie Canaguier, Cécile Morel, Valérie Miralles, Frédéric Veran, Jean-Marc Souquet, Véronique Cheynier, Nancy Terrier, Patrice This. Dissecting genetic architecture of grape proanthocyanidin composition through quantitative trait locus mapping.
BMC plant biology.
2012 Feb; 12(?):30. doi:
10.1186/1471-2229-12-30. [PMID: 22369244] - Christoph H Weinert, Stefanie Wiese, Harshadrai M Rawel, Tuba Esatbeyoglu, Peter Winterhalter, Thomas Homann, Sabine E Kulling. Methylation of catechins and procyanidins by rat and human catechol-O-methyltransferase: metabolite profiling and molecular modeling studies.
Drug metabolism and disposition: the biological fate of chemicals.
2012 Feb; 40(2):353-9. doi:
10.1124/dmd.111.041871. [PMID: 22071171] - Victoria Samanidou, Anastasios Tsagiannidis, Ioannis Sarakatsianos. Simultaneous determination of polyphenols and major purine alkaloids in Greek Sideritis species, herbal extracts, green tea, black tea, and coffee by high-performance liquid chromatography-diode array detection.
Journal of separation science.
2012 Feb; 35(4):608-15. doi:
10.1002/jssc.201100894. [PMID: 22282422] - Nik Kovinich, Ammar Saleem, John T Arnason, Brian Miki. Identification of two anthocyanidin reductase genes and three red-brown soybean accessions with reduced anthocyanidin reductase 1 mRNA, activity, and seed coat proanthocyanidin amounts.
Journal of agricultural and food chemistry.
2012 Jan; 60(2):574-84. doi:
10.1021/jf2033939. [PMID: 22107112] - Yixiang Wang, Qing Li, Qian Wang, Yujiao Li, Junhong Ling, Lili Liu, Xiaohui Chen, Kaishun Bi. Simultaneous determination of seven bioactive components in Oolong tea Camellia sinensis: quality control by chemical composition and HPLC fingerprints.
Journal of agricultural and food chemistry.
2012 Jan; 60(1):256-60. doi:
10.1021/jf204312w. [PMID: 22098505] - Jack W Blount, Mario Ferruzzi, Dan Raftery, Giulio M Pasinetti, Richard A Dixon. Enzymatic synthesis of substituted epicatechins for bioactivity studies in neurological disorders.
Biochemical and biophysical research communications.
2012 Jan; 417(1):457-61. doi:
10.1016/j.bbrc.2011.11.139. [PMID: 22166210] - Dioni A da Silva, Vanessa G Alves, Danielle M M Franco, Laryssa C Ribeiro, Maria C de Souza, Lucilia Kato, João E de Carvalho, Luciana K Kohn, Cecília M A de Oliveira, Cleuza C da Silva. Antiproliferative activity of Luehea candicans Mart. et Zucc. (Tiliaceae).
Natural product research.
2012; 26(4):364-9. doi:
10.1080/14786411003752102. [PMID: 21432719] - Min-Yong Kang, Yong Hyun Park, Bong Sub Kim, Su Yeon Seo, Byong Chang Jeong, Jung-In Kim, Hyeon Hoe Kim. Preventive effects of green tea (Camellia sinensis var. assamica) on diabetic nephropathy.
Yonsei medical journal.
2012 Jan; 53(1):138-44. doi:
10.3349/ymj.2012.53.1.138. [PMID: 22187244] - Kabir Mustapha Umar, S M Abdulkarim, Son Radu, Azizah Abdul Hamid, Nazamid Saari. Engineering the production of major catechins by Escherichia coli carrying metabolite genes of Camellia sinensis.
TheScientificWorldJournal.
2012; 2012(?):529031. doi:
10.1100/2012/529031. [PMID: 22645428] - S Mohd Joffry, N J Yob, M S Rofiee, M M R Meor Mohd Affandi, Z Suhaili, F Othman, A Md Akim, M N M Desa, Z A Zakaria. Melastoma malabathricum (L.) Smith Ethnomedicinal Uses, Chemical Constituents, and Pharmacological Properties: A Review.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):258434. doi:
10.1155/2012/258434. [PMID: 22242040] - G Suresh, Ashok K Tiwari, M Radha Krishna Murthy, D Anand Kumar, K Rajendra Prasad, R Ranga Rao, A Zehra Ali, K Suresh Babu. New advanced glycation end-products inhibitors from Dichrostachys cinerea Wight & Arn.
Journal of natural medicines.
2012 Jan; 66(1):213-6. doi:
10.1007/s11418-011-0557-3. [PMID: 21706215] - Manuel Gómez-Guzmán, Rosario Jiménez, Manuel Sánchez, María José Zarzuelo, Pilar Galindo, Ana María Quintela, Rocío López-Sepúlveda, Miguel Romero, Juan Tamargo, Félix Vargas, Francisco Pérez-Vizcaíno, Juan Duarte. Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension.
Free radical biology & medicine.
2012 Jan; 52(1):70-9. doi:
10.1016/j.freeradbiomed.2011.09.015. [PMID: 22001745] - S Vargas, K Ndjoko Ioset, A-E Hay, J-R Ioset, S Wittlin, K Hostettmann. Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation.
Journal of pharmaceutical and biomedical analysis.
2011 Dec; 56(5):880-6. doi:
10.1016/j.jpba.2011.06.026. [PMID: 21872416] - Lin-Lin Song, Ran Liang, Dan-Dan Li, Ya-Dong Xing, Rui-Min Han, Jian-Ping Zhang, Leif H Skibsted. β-carotene radical cation addition to green tea polyphenols. Mechanism of antioxidant antagonism in peroxidizing liposomes.
Journal of agricultural and food chemistry.
2011 Dec; 59(23):12643-51. doi:
10.1021/jf2030456. [PMID: 22023371] - Manuel Gómez-Guzmán, Rosario Jiménez, Manuel Sánchez, Miguel Romero, Francisco O'Valle, Rocío Lopez-Sepulveda, Ana María Quintela, Pilar Galindo, María José Zarzuelo, Elvira Bailón, Eva Delpón, Francisco Perez-Vizcaino, Juan Duarte. Chronic (-)-epicatechin improves vascular oxidative and inflammatory status but not hypertension in chronic nitric oxide-deficient rats.
The British journal of nutrition.
2011 Nov; 106(9):1337-48. doi:
10.1017/s0007114511004314. [PMID: 21910946] - Sasipawan Machana, Natthida Weerapreeyakul, Sahapat Barusrux, Apiyada Nonpunya, Bungorn Sripanidkulchai, Thaweesak Thitimetharoch. Cytotoxic and apoptotic effects of six herbal plants against the human hepatocarcinoma (HepG2) cell line.
Chinese medicine.
2011 Oct; 6(1):39. doi:
10.1186/1749-8546-6-39. [PMID: 22041055] - Jude C Ikewuchi, Eugene N Onyeike, Augustine A Uwakwe, Catherine C Ikewuchi. Effect of aqueous extract of the leaves of Acalypha wilkesiana 'Godseffiana' Muell Arg (Euphorbiaceae) on the hematology, plasma biochemistry and ocular indices of oxidative stress in alloxan induced diabetic rats.
Journal of ethnopharmacology.
2011 Oct; 137(3):1415-24. doi:
10.1016/j.jep.2011.08.015. [PMID: 21864665] - Kathrin Kahle, Michael Kempf, Peter Schreier, Wolfgang Scheppach, Dieter Schrenk, Tanja Kautenburger, Dorothée Hecker, Wolfgang Huemmer, Matthias Ackermann, Elke Richling. Intestinal transit and systemic metabolism of apple polyphenols.
European journal of nutrition.
2011 Oct; 50(7):507-22. doi:
10.1007/s00394-010-0157-0. [PMID: 21184087] - D Thakur, S C Das, S Sabhapondit, P Tamuly, D K Deka. Antimicrobial activities of tocklai vegetative tea clones.
Indian journal of microbiology.
2011 Oct; 51(4):450-5. doi:
10.1007/s12088-011-0190-6. [PMID: 23024406] - Victor P Bulgakov, G K Tchernoded, M V Veselova, S A Fedoreyev, T I Muzarok, Y N Zhuravlev. Catechin production in cultured cells of Taxus cuspidata and Taxus baccata.
Biotechnology letters.
2011 Sep; 33(9):1879-83. doi:
10.1007/s10529-011-0632-6. [PMID: 21544613] - Julia C Stingl, Thomas Ettrich, Rainer Muche, Martina Wiedom, Jürgen Brockmöller, Angela Seeringer, Thomas Seufferlein. Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population.
BMC cancer.
2011 Aug; 11(?):360. doi:
10.1186/1471-2407-11-360. [PMID: 21851602] - Cesar G Fraga, Patricia I Oteiza. Dietary flavonoids: Role of (-)-epicatechin and related procyanidins in cell signaling.
Free radical biology & medicine.
2011 Aug; 51(4):813-23. doi:
10.1016/j.freeradbiomed.2011.06.002. [PMID: 21699974] - Nam Il Park, Hui Xu, Xiaohua Li, In Hyuk Jang, Suhyoung Park, Gil Hwan Ahn, Yong Pyo Lim, Sun Ju Kim, Sang Un Park. Anthocyanin accumulation and expression of anthocyanin biosynthetic genes in radish (Raphanus sativus).
Journal of agricultural and food chemistry.
2011 Jun; 59(11):6034-9. doi:
10.1021/jf200824c. [PMID: 21548630] - I-Hua Wei, Hui-Chin Tu, Chih-Chia Huang, Mang-Hung Tsai, Chi-Yu Tseng, Jeng-Yung Shieh. (-)-Epigallocatechin gallate attenuates NADPH-d/nNOS expression in motor neurons of rats following peripheral nerve injury.
BMC neuroscience.
2011 Jun; 12(?):52. doi:
10.1186/1471-2202-12-52. [PMID: 21627848] - Gary Williamson, Fabiola Dionisi, Mathieu Renouf. Flavanols from green tea and phenolic acids from coffee: critical quantitative evaluation of the pharmacokinetic data in humans after consumption of single doses of beverages.
Molecular nutrition & food research.
2011 Jun; 55(6):864-73. doi:
10.1002/mnfr.201000631. [PMID: 21538847] - J S Tang, Y L Hou, H Gao, X Chen, S C Sun, T Z Guo, H Kobayashi, W C Ye, X S Yao. Polyphenols from Parabarium huaitingii and their positive inotropic and anti-myocardial infarction effects in rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2011 May; 18(7):544-50. doi:
10.1016/j.phymed.2010.10.020. [PMID: 21530209] - Mareike Reichel, Reinhold Carle, Pittaya Sruamsiri, Sybille Neidhart. Changes in flavonoids and nonphenolic pigments during on-tree maturation and postharvest pericarp browning of litchi (Litchi chinensis Sonn.) as shown by HPLC-MSn.
Journal of agricultural and food chemistry.
2011 Apr; 59(8):3924-39. doi:
10.1021/jf104432r. [PMID: 21413696] - Mari Maeda-Yamamoto, Kaori Ema, Yoshiko Tokuda, Manami Monobe, Hirofumi Tachibana, Yoichi Sameshima, Shinichi Kuriyama. Effect of green tea powder (Camellia sinensis L. cv. Benifuuki) particle size on O-methylated EGCG absorption in rats; The Kakegawa Study.
Cytotechnology.
2011 Mar; 63(2):171-9. doi:
10.1007/s10616-010-9331-8. [PMID: 21207145] - Akiko Yasuda, Midori Natsume, Naomi Osakabe, Keiko Kawahata, Jinichiro Koga. Cacao polyphenols influence the regulation of apolipoprotein in HepG2 and Caco2 cells.
Journal of agricultural and food chemistry.
2011 Feb; 59(4):1470-6. doi:
10.1021/jf103820b. [PMID: 21226458] - Masami Suganuma, Achinto Saha, Hirota Fujiki. New cancer treatment strategy using combination of green tea catechins and anticancer drugs.
Cancer science.
2011 Feb; 102(2):317-23. doi:
10.1111/j.1349-7006.2010.01805.x. [PMID: 21199169] - Maja Jakesevic, Kjersti Aaby, Grethe-Iren A Borge, Bengt Jeppsson, Siv Ahrné, Göran Molin. Antioxidative protection of dietary bilberry, chokeberry and Lactobacillus plantarum HEAL19 in mice subjected to intestinal oxidative stress by ischemia-reperfusion.
BMC complementary and alternative medicine.
2011 Jan; 11(?):8. doi:
10.1186/1472-6882-11-8. [PMID: 21272305] - Iker Hernández, Leonor Alegre, Sergi Munné-Bosch. Plant aging and excess light enhance flavan-3-ol content in Cistus clusii.
Journal of plant physiology.
2011 Jan; 168(2):96-102. doi:
10.1016/j.jplph.2010.06.026. [PMID: 20817313] - Javier I Ottaviani, Tony Y Momma, Christian Heiss, Catherine Kwik-Uribe, Hagen Schroeter, Carl L Keen. The stereochemical configuration of flavanols influences the level and metabolism of flavanols in humans and their biological activity in vivo.
Free radical biology & medicine.
2011 Jan; 50(2):237-44. doi:
10.1016/j.freeradbiomed.2010.11.005. [PMID: 21074608] - Yan Jiang, Xinyong Liu, Erik De Clercq. New therapeutic approaches targeted at the late stages of the HIV-1 replication cycle.
Current medicinal chemistry.
2011; 18(1):16-28. doi:
10.2174/092986711793979751. [PMID: 21110817] - Mathieu Renouf, Philippe Guy, Cynthia Marmet, Karin Longet, Anne-Lise Fraering, Julie Moulin, Denis Barron, Fabiola Dionisi, Christophe Cavin, Heike Steiling, Gary Williamson. Plasma appearance and correlation between coffee and green tea metabolites in human subjects.
The British journal of nutrition.
2010 Dec; 104(11):1635-40. doi:
10.1017/s0007114510002709. [PMID: 20691128] - Jean Jules Kezetas Bankeu, Sufyan Awad Alkarim Mustafa, Anar Sahib Gojayev, Bruno Djakou Lenta, Didérot Tchamo Noungoué, Silvère Augustin Ngouela, Khalid Asaad, Mohammed Iqbal Choudhary, Sean Prigge, Akif Alekper Guliyev, Augustin Ephrem Nkengfack, Etienne Tsamo, Muhammad Shaiq Ali. Ceramide and Cerebroside from the stem bark of Ficus mucuso (Moraceae).
Chemical & pharmaceutical bulletin.
2010 Dec; 58(12):1661-5. doi:
10.1248/cpb.58.1661. [PMID: 21139276] - Motoki Iwasaki, Manami Inoue, Shizuka Sasazuki, Tsutomu Miura, Norie Sawada, Taiki Yamaji, Taichi Shimazu, Walter C Willett, Shoichiro Tsugane. Plasma tea polyphenol levels and subsequent risk of breast cancer among Japanese women: a nested case-control study.
Breast cancer research and treatment.
2010 Dec; 124(3):827-34. doi:
10.1007/s10549-010-0916-x. [PMID: 20440552] - Manabu Ueda, Takashi Furuyashiki, Kayo Yamada, Yukiko Aoki, Iwao Sakane, Itsuko Fukuda, Ken-Ichi Yoshida, Hitoshi Ashida. Tea catechins modulate the glucose transport system in 3T3-L1 adipocytes.
Food & function.
2010 Nov; 1(2):167-73. doi:
10.1039/c0fo00105h. [PMID: 21776468] - Daniele Del Rio, Luca Calani, Chiara Cordero, Sara Salvatore, Nicoletta Pellegrini, Furio Brighenti. Bioavailability and catabolism of green tea flavan-3-ols in humans.
Nutrition (Burbank, Los Angeles County, Calif.).
2010 Nov; 26(11-12):1110-6. doi:
10.1016/j.nut.2009.09.021. [PMID: 20080030] - Markus Schantz, Thomas Erk, Elke Richling. Metabolism of green tea catechins by the human small intestine.
Biotechnology journal.
2010 Oct; 5(10):1050-9. doi:
10.1002/biot.201000214. [PMID: 20931601] - Jian Sun, Ezhen Zhang, Liangxiong Xu, Zhichun Li, Zhenxing Wang, Changbao Li. Comparison on characterization of longan (Dimocarpus longan Lour.) polyphenoloxidase using endogenous and exogenous substrates.
Journal of agricultural and food chemistry.
2010 Sep; 58(18):10195-201. doi:
10.1021/jf101639d. [PMID: 20718432] - S M Kamruzzaman, Mehari Endale, Won Jun Oh, Seung-Chun Park, Kil-Soo Kim, Joo Heon Hong, Yi-Seong Kwak, Bong-Sik Yun, Man Hee Rhee. Inhibitory effects of Bulnesia sarmienti aqueous extract on agonist-induced platelet activation and thrombus formation involves mitogen-activated protein kinases.
Journal of ethnopharmacology.
2010 Aug; 130(3):614-20. doi:
10.1016/j.jep.2010.05.049. [PMID: 20558266] - Ki Sung Kang, Yujing Wen, Noriko Yamabe, Masayuki Fukui, Stephanie C Bishop, Bao Ting Zhu. Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies.
PloS one.
2010 Aug; 5(8):e11951. doi:
10.1371/journal.pone.0011951. [PMID: 20700524] - Piwen Wang, William J Aronson, Min Huang, Yanjun Zhang, Ru-Po Lee, David Heber, Susanne M Henning. Green tea polyphenols and metabolites in prostatectomy tissue: implications for cancer prevention.
Cancer prevention research (Philadelphia, Pa.).
2010 Aug; 3(8):985-93. doi:
10.1158/1940-6207.capr-09-0210. [PMID: 20628004] - Dottie R Brundige, Elizabeth A Maga, Kirk C Klasing, James D Murray. Consumption of pasteurized human lysozyme transgenic goats' milk alters serum metabolite profile in young pigs.
Transgenic research.
2010 Aug; 19(4):563-74. doi:
10.1007/s11248-009-9334-4. [PMID: 19847666] - Achinto Saha, Takashi Kuzuhara, Noriko Echigo, Masami Suganuma, Hirota Fujiki. New role of (-)-epicatechin in enhancing the induction of growth inhibition and apoptosis in human lung cancer cells by curcumin.
Cancer prevention research (Philadelphia, Pa.).
2010 Aug; 3(8):953-62. doi:
10.1158/1940-6207.capr-09-0247. [PMID: 20606042] - Swati Kalgaonkar, Hiroshi Nishioka, Heidrun B Gross, Hajime Fujii, Carl L Keen, Robert M Hackman. Bioactivity of a flavanol-rich lychee fruit extract in adipocytes and its effects on oxidant defense and indices of metabolic syndrome in animal models.
Phytotherapy research : PTR.
2010 Aug; 24(8):1223-8. doi:
10.1002/ptr.3137. [PMID: 20309950] - Jia-Hua Li, Atsushi Nesumi, Keiichi Shimizu, Yusuke Sakata, Ming-Zhi Liang, Qing-Yuan He, Hong-Jie Zhou, Fumio Hashimoto. Chemosystematics of tea trees based on tea leaf polyphenols as phenetic markers.
Phytochemistry.
2010 Aug; 71(11-12):1342-9. doi:
10.1016/j.phytochem.2010.05.002. [PMID: 20553697] - Nobuyuki Hayashi, Ronggang Chen, Masamitsu Hiraoka, Tomomi Ujihara, Hidekazu Ikezaki. Beta-cyclodextrin/surface plasmon resonance detection system for sensing bitter-astringent taste intensity of green tea catechins.
Journal of agricultural and food chemistry.
2010 Jul; 58(14):8351-6. doi:
10.1021/jf1012693. [PMID: 20572674] - Yunbao Liu, Muraleedharan G Nair. An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.
Journal of natural products.
2010 Jul; 73(7):1193-5. doi:
10.1021/np1000945. [PMID: 20565070] - Tuba Esatbeyoglu, Victor Wray, Peter Winterhalter. Dimeric procyanidins: screening for B1 to B8 and semisynthetic preparation of B3, B4, B6, And B8 from a polymeric procyanidin fraction of white willow bark (Salix alba).
Journal of agricultural and food chemistry.
2010 Jul; 58(13):7820-30. doi:
10.1021/jf101023e. [PMID: 20533825] - Elisa Becatti, Lamia Chkaiban, Pietro Tonutti, Claudio Forcato, Claudio Bonghi, Anna Maria Ranieri. Short-term postharvest carbon dioxide treatments induce selective molecular and metabolic changes in grape berries.
Journal of agricultural and food chemistry.
2010 Jul; 58(13):8012-20. doi:
10.1021/jf100936x. [PMID: 20557098] - Weihuan Huang, Xiaoli Zhang, Yifei Wang, Wencai Ye, Vincent Ec Ooi, Hau Yin Chung, Yaolan Li. Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen).
Chinese medicine.
2010 Jun; 5(?):23. doi:
10.1186/1749-8546-5-23. [PMID: 20565950] - M A Susan Marles, Parthiba Balasubramanian, Kirstin E Bett. Differential accumulation of polyphenolics in black bean genotypes grown in four environments.
Journal of agricultural and food chemistry.
2010 Jun; 58(11):7001-6. doi:
10.1021/jf100630g. [PMID: 20481468] - Stavroula Stoupi, Gary Williamson, J Warren Drynan, Denis Barron, Michael N Clifford. A comparison of the in vitro biotransformation of (-)-epicatechin and procyanidin B2 by human faecal microbiota.
Molecular nutrition & food research.
2010 Jun; 54(6):747-59. doi:
10.1002/mnfr.200900123. [PMID: 19943260] - Christina Ritter, Benno F Zimmermann, Rudolf Galensa. Chiral separation of (+)/(-)-catechin from sulfated and glucuronidated metabolites in human plasma after cocoa consumption.
Analytical and bioanalytical chemistry.
2010 May; 397(2):723-30. doi:
10.1007/s00216-010-3542-x. [PMID: 20213173] - Wai Mun Loke, Julie M Proudfoot, Jonathan M Hodgson, Allan J McKinley, Neil Hime, Maria Magat, Roland Stocker, Kevin D Croft. Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.
Arteriosclerosis, thrombosis, and vascular biology.
2010 Apr; 30(4):749-57. doi:
10.1161/atvbaha.109.199687. [PMID: 20093625] - Elías Obreque-Slier, Alvaro Peña-Neira, Remigio López-Solís, Fernando Zamora-Marín, Jorge M Ricardo-da Silva, Olga Laureano. Comparative study of the phenolic composition of seeds and skins from Carménère and Cabernet Sauvignon grape varieties (Vitis vinifera L.) during ripening.
Journal of agricultural and food chemistry.
2010 Mar; 58(6):3591-9. doi:
10.1021/jf904314u. [PMID: 20163111] - Angélique Stalmach, William Mullen, Heike Steiling, Gary Williamson, Michael E J Lean, Alan Crozier. Absorption, metabolism, and excretion of green tea flavan-3-ols in humans with an ileostomy.
Molecular nutrition & food research.
2010 Mar; 54(3):323-34. doi:
10.1002/mnfr.200900194. [PMID: 19937856] - Baojun Xu, Sam K C Chang. Phenolic substance characterization and chemical and cell-based antioxidant activities of 11 lentils grown in the northern United States.
Journal of agricultural and food chemistry.
2010 Feb; 58(3):1509-17. doi:
10.1021/jf903532y. [PMID: 20058926] - Christian Rössle, Hilde H Wijngaard, Ronan T Gormley, Francis Butler, Nigel Brunton. Effect of storage on the content of polyphenols of minimally processed skin-on apple wedges from ten cultivars and two growing seasons.
Journal of agricultural and food chemistry.
2010 Feb; 58(3):1609-14. doi:
10.1021/jf903621y. [PMID: 20000411] - Volodymyr Samoylenko, Md Mostafizur Rahman, Babu L Tekwani, Lalit M Tripathi, Yan-Hong Wang, Shabana I Khan, Ikhlas A Khan, Loren S Miller, Vaishali C Joshi, Ilias Muhammad. Banisteriopsis caapi, a unique combination of MAO inhibitory and antioxidative constituents for the activities relevant to neurodegenerative disorders and Parkinson's disease.
Journal of ethnopharmacology.
2010 Feb; 127(2):357-67. doi:
10.1016/j.jep.2009.10.030. [PMID: 19879939] - Ipek Peşin Süntar, Esra Küpeli Akkol, Demet Yilmazer, Turhan Baykal, Hasan Kirmizibekmez, Murat Alper, Erdem Yeşilada. Investigations on the in vivo wound healing potential of Hypericum perforatum L.
Journal of ethnopharmacology.
2010 Feb; 127(2):468-77. doi:
10.1016/j.jep.2009.10.011. [PMID: 19833187] - Song-Chwan Fang, Chin-Lin Hsu, Hsin-Tang Lin, Gow-Chin Yen. Anticancer effects of flavonoid derivatives isolated from Millettia reticulata Benth in SK-Hep-1 human hepatocellular carcinoma cells.
Journal of agricultural and food chemistry.
2010 Jan; 58(2):814-20. doi:
10.1021/jf903216r. [PMID: 19994890] - G Korte, A Dreiseitel, P Schreier, A Oehme, S Locher, S Geiger, J Heilmann, P G Sand. Tea catechins' affinity for human cannabinoid receptors.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2010 Jan; 17(1):19-22. doi:
10.1016/j.phymed.2009.10.001. [PMID: 19897346] - Kanako Minoda, Tatsuya Ichikawa, Tomoharu Katsumata, Ken-ichi Onobori, Taiki Mori, Yukiko Suzuki, Takeshi Ishii, Tsutomu Nakayama. Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin.
Journal of nutritional science and vitaminology.
2010; 56(5):331-4. doi:
10.3177/jnsv.56.331. [PMID: 21228505] - Masashi Sato, Hajime Toyazaki, Yu Yoshioka, Nobutoshi Yokoi, Toru Yamasaki. Structural characteristics for superoxide anion radical scavenging and productive activities of green tea polyphenols including proanthocyanidin dimers.
Chemical & pharmaceutical bulletin.
2010 Jan; 58(1):98-102. doi:
10.1248/cpb.58.98. [PMID: 20045974] - Claudia Velázquez, Fernando Calzada, Baldomero Esquivel, Elizabeth Barbosa, Samuel Calzada. Antisecretory activity from the flowers of Chiranthodendron pentadactylon and its flavonoids on intestinal fluid accumulation induced by Vibrio cholerae toxin in rats.
Journal of ethnopharmacology.
2009 Dec; 126(3):455-8. doi:
10.1016/j.jep.2009.09.016. [PMID: 19781621] - Yulong Chen, Jun Duan, Shaoyu Yang, En Yang, Yuming Jiang. Effect of girdling on levels of catechins in fresh leaf in relation to quality of 'Huang Zhi Xiang' Oolong' tea.
Plant foods for human nutrition (Dordrecht, Netherlands).
2009 Dec; 64(4):293-6. doi:
10.1007/s11130-009-0139-7. [PMID: 19898938] - Mireia Urpi-Sarda, María Monagas, Nasiruddin Khan, Rafael Llorach, Rosa Ma Lamuela-Raventós, Olga Jáuregui, Ramón Estruch, María Izquierdo-Pulido, Cristina Andrés-Lacueva. Targeted metabolic profiling of phenolics in urine and plasma after regular consumption of cocoa by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. A.
2009 Oct; 1216(43):7258-67. doi:
10.1016/j.chroma.2009.07.058. [PMID: 19671472] - Zhi Na, Youkai Xu. [Chemical constituents from twigs of Garcinia xipshuanbannaensis].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2009 Sep; 34(18):2338-42. doi:
. [PMID: 20030083] - A Vidhya, M Indira. Protective effect of Quercetin in the Regression of Ethanol-Induced Hepatotoxicity.
Indian journal of pharmaceutical sciences.
2009 Sep; 71(5):527-32. doi:
10.4103/0250-474x.58186. [PMID: 20502571] - Yuan Zhang, Zhe-zhi Wang. Phenolic composition and antioxidant activities of two Phlomis species: A correlation study.
Comptes rendus biologies.
2009 Sep; 332(9):816-26. doi:
10.1016/j.crvi.2009.05.006. [PMID: 19748456] - Masahiko Takeshita, Yo-Ichi Ishida, Ena Akamatsu, Yusuke Ohmori, Masayuki Sudoh, Hirofumi Uto, Hirohito Tsubouchi, Hiroaki Kataoka. Proanthocyanidin from blueberry leaves suppresses expression of subgenomic hepatitis C virus RNA.
The Journal of biological chemistry.
2009 Aug; 284(32):21165-76. doi:
10.1074/jbc.m109.004945. [PMID: 19531480] - Renqiang Mei, Hengxing Liang, Junfeng Wang, Linhong Zeng, Qing Lu, Yongxian Cheng. New seco-anthraquinone glucosides from Rumex nepalensis.
Planta medica.
2009 Aug; 75(10):1162-4. doi:
10.1055/s-0029-1185467. [PMID: 19291613] - Roberto Gotti, Sandra Furlanetto, Silvia Lanteri, Stefano Olmo, Alessandro Ragaini, Vanni Cavrini. Differentiation of green tea samples by chiral CD-MEKC analysis of catechins content.
Electrophoresis.
2009 Aug; 30(16):2922-30. doi:
10.1002/elps.200800795. [PMID: 19637216] - Mi Hee Yu, Hyo Gwon Im, Hyuk-Il Kim, In-Seon Lee. Induction of apoptosis by immature plum in human hepatocellular carcinoma.
Journal of medicinal food.
2009 Jun; 12(3):518-27. doi:
10.1089/jmf.2008.1268. [PMID: 19627199] - R Bahri-Sahloul, S Ammar, R B Fredj, S Saguem, S Grec, F Trotin, F H Skhiri. Polyphenol contents and antioxidant activities of extracts from flowers of two Crataegus azarolus L. varieties.
Pakistan journal of biological sciences : PJBS.
2009 May; 12(9):660-8. doi:
10.3923/pjbs.2009.660.668. [PMID: 19634468] - Marina S Figueiroa, Juliany S B César Vieira, Disleide S Leite, Ruben C O Andrade Filho, Fabiano Ferreira, Patrícia S Gouveia, Daniel P Udrisar, Maria I Wanderley. Green tea polyphenols inhibit testosterone production in rat Leydig cells.
Asian journal of andrology.
2009 May; 11(3):362-70. doi:
10.1038/aja.2009.2. [PMID: 19330017]