Phytyl diphosphate (BioDeep_00000005817)

 

Secondary id: BioDeep_00000638554

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


{[hydroxy({[(2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl]oxy})phosphoryl]oxy}phosphonic acid

化学式: C20H42O7P2 (456.2405642)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 0.1%

分子结构信息

SMILES: CC(=CCOP(=O)(O)OP(=O)(O)O)CCCC(C)CCCC(C)CCCC(C)C
InChI: InChI=1S/C20H42O7P2/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-26-29(24,25)27-28(21,22)23/h15,17-19H,6-14,16H2,1-5H3,(H,24,25)(H2,21,22,23)/b20-15+

描述信息

Phytyl diphosphate participates in biosynthesis of steroids as well as porphyrin and metabolism. Phytyl diphosphate is produced from Geranylgeranyl diphosphate in biosynthesis of steroids. [HMDB]. Phytyl diphosphate is found in many foods, some of which are highbush blueberry, wild leek, evergreen huckleberry, and allium (onion).
Phytyl diphosphate participates in biosynthesis of steroids as well as porphyrin and metabolism. Phytyl diphosphate is produced from Geranylgeranyl diphosphate in biosynthesis of steroids.

同义名列表

7 个代谢物同义名

{[hydroxy({[(2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl]oxy})phosphoryl]oxy}phosphonic acid; (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate; (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate; Phytyl diphosphoric acid; Phytyl diphosphate; 3R,7R,11R,15-tetramethyl-2E-hexadecen-1-ol diphosphate; SCHEMBL1067195



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

516 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(514)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(2)

  • Phylloquinol Biosynthesis: 2-carboxy-1,4-naphthoquinone + Hydrogen Ion + Phytyl diphosphate ⟶ Carbon dioxide + Demethylphylloquinone + Pyrophosphate
  • Chlorophyll a Biosynthesis I: Geranylgeranyl-PP + Hydrogen Ion + NADPH ⟶ NADP + dihydrogeranylgeranyl diphosphate

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Paula Muñoz, Verónica Tijero, Celia Vincent, Sergi Munné-Bosch. Abscisic acid triggers vitamin E accumulation by transient transcript activation of VTE5 and VTE6 in sweet cherry fruits. The Biochemical journal. 2024 Feb; ?(?):. doi: 10.1042/bcj20230399. [PMID: 38314636]
  • Yueli Tang, Xueqing Fu, Qian Shen, Kexuan Tang. Roles of MPBQ-MT in Promoting α/γ-Tocopherol Production and Photosynthesis under High Light in Lettuce. PloS one. 2016; 11(2):e0148490. doi: 10.1371/journal.pone.0148490. [PMID: 26867015]
  • Katharina Vom Dorp, Georg Hölzl, Christian Plohmann, Marion Eisenhut, Marion Abraham, Andreas P M Weber, Andrew D Hanson, Peter Dörmann. Remobilization of Phytol from Chlorophyll Degradation Is Essential for Tocopherol Synthesis and Growth of Arabidopsis. The Plant cell. 2015 Oct; 27(10):2846-59. doi: 10.1105/tpc.15.00395. [PMID: 26452599]
  • Qing Li, Xiaohong Yang, Shutu Xu, Ye Cai, Dalong Zhang, Yingjia Han, Lin Li, Zuxin Zhang, Shibin Gao, Jiansheng Li, Jianbing Yan. Genome-wide association studies identified three independent polymorphisms associated with α-tocopherol content in maize kernels. PloS one. 2012; 7(5):e36807. doi: 10.1371/journal.pone.0036807. [PMID: 22615816]
  • Maria S Dwiyanti, Tetsuya Yamada, Masako Sato, Jun Abe, Keisuke Kitamura. Genetic variation of γ-tocopherol methyltransferase gene contributes to elevated α-tocopherol content in soybean seeds. BMC plant biology. 2011 Nov; 11(?):152. doi: 10.1186/1471-2229-11-152. [PMID: 22053941]
  • Stuart Meier, Oren Tzfadia, Ratnakar Vallabhaneni, Chris Gehring, Eleanore T Wurtzel. A transcriptional analysis of carotenoid, chlorophyll and plastidial isoprenoid biosynthesis genes during development and osmotic stress responses in Arabidopsis thaliana. BMC systems biology. 2011 May; 5(?):77. doi: 10.1186/1752-0509-5-77. [PMID: 21595952]
  • Wenyu Yang, Rebecca E Cahoon, Sarah C Hunter, Chunyu Zhang, Jixiang Han, Trissa Borgschulte, Edgar B Cahoon. Vitamin E biosynthesis: functional characterization of the monocot homogentisate geranylgeranyl transferase. The Plant journal : for cell and molecular biology. 2011 Jan; 65(2):206-17. doi: 10.1111/j.1365-313x.2010.04417.x. [PMID: 21223386]
  • Kristina L Ford, Andrew Cassin, Antony Bacic. Quantitative proteomic analysis of wheat cultivars with differing drought stress tolerance. Frontiers in plant science. 2011; 2(?):44. doi: 10.3389/fpls.2011.00044. [PMID: 22639595]
  • Arto J Soitamo, Mirva Piippo, Yagut Allahverdiyeva, Natalia Battchikova, Eva-Mari Aro. Light has a specific role in modulating Arabidopsis gene expression at low temperature. BMC plant biology. 2008 Jan; 8(?):13. doi: 10.1186/1471-2229-8-13. [PMID: 18230142]
  • Li Tian, Dean DellaPenna, Richard A Dixon. The pds2 mutation is a lesion in the Arabidopsis homogentisate solanesyltransferase gene involved in plastoquinone biosynthesis. Planta. 2007 Sep; 226(4):1067-73. doi: 10.1007/s00425-007-0564-5. [PMID: 17569077]
  • Till Ischebeck, Anna Maria Zbierzak, Marion Kanwischer, Peter Dörmann. A salvage pathway for phytol metabolism in Arabidopsis. The Journal of biological chemistry. 2006 Feb; 281(5):2470-7. doi: 10.1074/jbc.m509222200. [PMID: 16306049]
  • Masaru Shibata, Michito Tsuyama, Tsuneaki Takami, Hideyuki Shimizu, Yoshichika Kobayashi. Accumulation of menaquinones with incompletely reduced side chains and loss of alpha-tocopherol in rice mutants with alternations in the chlorophyll moiety. Journal of experimental botany. 2004 Sep; 55(405):1989-96. doi: 10.1093/jxb/erh218. [PMID: 15286146]
  • Eva Collakova, Dean DellaPenna. Homogentisate phytyltransferase activity is limiting for tocopherol biosynthesis in Arabidopsis. Plant physiology. 2003 Feb; 131(2):632-42. doi: 10.1104/pp.015222. [PMID: 12586887]
  • Beth Savidge, James D Weiss, Yun-Hua H Wong, Michael W Lassner, Timothy A Mitsky, Christine K Shewmaker, Dusty Post-Beittenmiller, Henry E Valentin. Isolation and characterization of homogentisate phytyltransferase genes from Synechocystis sp. PCC 6803 and Arabidopsis. Plant physiology. 2002 May; 129(1):321-32. doi: 10.1104/pp.010747. [PMID: 12011362]
  • E Collakova, D DellaPenna. Isolation and functional analysis of homogentisate phytyltransferase from Synechocystis sp. PCC 6803 and Arabidopsis. Plant physiology. 2001 Nov; 127(3):1113-24. doi: . [PMID: 11706191]
  • T Grasses, B Grimm, O Koroleva, P Jahns. Loss of alpha-tocopherol in tobacco plants with decreased geranylgeranyl reductase activity does not modify photosynthesis in optimal growth conditions but increases sensitivity to high-light stress. Planta. 2001 Aug; 213(4):620-8. doi: 10.1007/s004250100532. [PMID: 11556795]