7,8-diaminopelargonate (BioDeep_00000004548)

 

Secondary id: BioDeep_00000629251

human metabolite


代谢物信息卡片


7,8-Diaminopelargonic acid

化学式: C9H20N2O2 (188.1525)
中文名称: 7,8-氨基壬酸
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 15.06%

分子结构信息

SMILES: CC(C(CCCCCC(=O)O)N)N
InChI: InChI=1S/C9H20N2O2/c1-7(10)8(11)5-3-2-4-6-9(12)13/h7-8H,2-6,10-11H2,1H3,(H,12,13)

描述信息

7,8-diaminononanoate, also known as 7,8-dap or 7,8-diaminopelargonic acid, is a member of the class of compounds known as medium-chain fatty acids. Medium-chain fatty acids are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms. Thus, 7,8-diaminononanoate is considered to be a fatty acid lipid molecule. 7,8-diaminononanoate is slightly soluble (in water) and a weakly acidic compound (based on its pKa). 7,8-diaminononanoate can be found in a number of food items such as devilfish, walnut, rapini, and swamp cabbage, which makes 7,8-diaminononanoate a potential biomarker for the consumption of these food products. 7,8-diaminononanoate exists in E.coli (prokaryote) and yeast (eukaryote).

同义名列表

8 个代谢物同义名

7,8-Diaminopelargonic acid; 7,8-Diaminononanoic acid; 7,8-diaminopelargonate; 7,8-Diaminononanoate; 7,8-DAPA; 7,8-DAP; DAPA; DAP



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

246 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(246)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Gianlorenzo Dionigi, Sam Van Slycke, Stefano Rausei, Luigi Boni, Renzo Dionigi. Parathyroid function after open thyroidectomy: A prospective randomized study for ligasure precise versus harmonic FOCUS. Head & neck. 2013 Apr; 35(4):562-7. doi: 10.1002/hed.23005. [PMID: 22715020]
  • David Cobessi, Renaud Dumas, Virginie Pautre, Céline Meinguet, Jean-Luc Ferrer, Claude Alban. Biochemical and structural characterization of the Arabidopsis bifunctional enzyme dethiobiotin synthetase-diaminopelargonic acid aminotransferase: evidence for substrate channeling in biotin synthesis. The Plant cell. 2012 Apr; 24(4):1608-25. doi: 10.1105/tpc.112.097675. [PMID: 22547782]
  • Susanna Roeder, Katharina Dreschler, Markus Wirtz, Simona M Cristescu, Frans J M van Harren, Rüdiger Hell, Birgit Piechulla. SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers. Plant molecular biology. 2009 Jul; 70(5):535-46. doi: 10.1007/s11103-009-9490-1. [PMID: 19396585]
  • Je-Gun Joung, Zhangjun Fei. Computational identification of condition-specific miRNA targets based on gene expression profiles and sequence information. BMC bioinformatics. 2009 Jan; 10 Suppl 1(?):S34. doi: 10.1186/1471-2105-10-s1-s34. [PMID: 19208135]
  • Vikrant M Bhor, Sagarika Dev, Ganga Ramu Vasanthakumar, Avadhesha Surolia. Spectral and kinetic characterization of 7,8-diaminopelargonic acid synthase from Mycobacterium tuberculosis. IUBMB life. 2006 Apr; 58(4):225-33. doi: 10.1080/15216540600746997. [PMID: 16754301]
  • Violaine Pinon, Stéphane Ravanel, Roland Douce, Claude Alban. Biotin synthesis in plants. The first committed step of the pathway is catalyzed by a cytosolic 7-keto-8-aminopelargonic acid synthase. Plant physiology. 2005 Dec; 139(4):1666-76. doi: 10.1104/pp.105.070144. [PMID: 16299174]
  • D A Patton, S Volrath, E R Ward. Complementation of an Arabidopsis thaliana biotin auxotroph with an Escherichia coli biotin biosynthetic gene. Molecular & general genetics : MGG. 1996 Jun; 251(3):261-6. doi: 10.1007/bf02172516. [PMID: 8676868]
  • T Fukushima. [Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 1975 Jul; 71(5):457-62. doi: . [PMID: 280]