corytuberine (BioDeep_00000003726)
natural product PANOMIX_OTCML-2023
代谢物信息卡片
(S)-corytuberine
化学式: C19H21NO4 (327.14705060000006)
中文名称: 紫堇块茎碱
谱图信息:
最多检出来源 Viridiplantae(plant) 0.71%
分子结构信息
SMILES: CN1CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)O)O)OC
InChI: InChI=1S/C19H21NO4/c1-20-7-6-11-9-14(24-3)19(22)17-15(11)12(20)8-10-4-5-13(23-2)18(21)16(10)17/h4-5,9,12,21-22H,6-8H2,1-3H3/t12-/m0/s1
描述信息
An aporphine alkaloid that is aporphine which is substituted by hydroxy groups at positions 1 and 11, and by methoxy groups at positions 2 and 10 (the S enantiomer).
同义名列表
3 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:81200
- KEGG: C17591
- PubChem: 160500
- Metlin: METLIN64383
- ChEMBL: CHEMBL227965
- MetaCyc: CPD-9935
- CAS: 517-56-6
- MoNA: PM010812
- PMhub: MS000011156
- MetaboLights: MTBLC81200
- PubChem: 96023936
- KNApSAcK: C00025655
- NIKKAJI: J6.577C
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
28 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(28)
- magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH - magnoflorine biosynthesis:
(S)-corytuberine + SAM ⟶ (S)-magnoflorine + H+ + SAH
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
59 个相关的物种来源信息
- 1496660 - Aconitum plicatum: 10.1135/CCCC19951034
- 64025 - Actaea spicata: 10.1135/CCCC19951034
- 113211 - Adonis aestivalis: 10.1135/CCCC19870804
- 46985 - Adonis vernalis: 10.1135/CCCC19870804
- 49314 - Annona cherimola: 10.1021/NP50037A038
- 49857 - Annona montana: 10.1021/NP8001282
- 3450 - Aquilegia: 10.1135/CCCC19870804
- 158538 - Aristolochia clematitis: 10.1135/CCCC19870804
- 12948 - Aristolochia gigantea: 10.3390/MOLECULES15129462
- 203270 - Berberis aquifolium: 10.1055/S-2006-958107
- 3449 - Caltha palustris: 10.1135/CCCC19870804
- 13393 - Cananga odorata: 10.1002/JCCS.199900084
- 108409 - Cissampelos pareira: 10.1016/0031-9422(75)80388-8
- 1857144 - Clematis parviloba: 10.1007/S12272-009-1111-7
- 748711 - Clematis recta: 10.1135/CCCC19870804
- 984867 - Consolida regalis: 10.1135/CCCC19870804
- 404569 - Corydalis ambigua: 10.1016/S0367-326X(99)00045-3
- 581246 - Corydalis cava: 10.1039/CT8936300485
- 404570 - Corydalis incisa: 10.1016/S0367-326X(99)00045-3
- 38909 - Corydalis nobilis:
- 128613 - Dehaasia incrassata: 10.1016/0031-9422(89)80062-7
- 1127184 - Delphinium pentagynum: 10.1016/J.PHYTOCHEM.2004.03.017
- 332430 - Dicentra formosa: 10.1139/CJR34-047
- 37492 - Eranthis hyemalis: 10.1135/CCCC19870804
- 453234 - Fissistigma oldhamii: 10.1016/J.BMC.2006.10.034
- 1095357 - Fumaria agraria: 10.1002/(SICI)1099-1565(199901/02)10:1<6::AID-PCA431>3.0.CO;2-0
- 1464607 - Fumaria barnolae: 10.1002/(SICI)1099-1565(199901/02)10:1<6::AID-PCA431>3.0.CO;2-0
- 1092452 - Fumaria densiflora:
- 200993 - Fumaria officinalis: 10.1002/(SICI)1099-1565(199901/02)10:1<6::AID-PCA431>3.0.CO;2-0
- 367484 - Fumaria vaillantii: 10.1002/(SICI)1099-1565(199901/02)10:1<6::AID-PCA431>3.0.CO;2-0
- 1353837 - Glaucium fimbrilligerum: 10.1007/BF00575709
- 1353838 - Glaucium squamigerum: 10.1135/CCCC19841318
- 46996 - Helleborus foetidus: 10.1135/CCCC19870804
- 171896 - Helleborus niger: 10.1135/CCCC19870804
- 171903 - Helleborus viridis: 10.1135/CCCC19870804
- 482941 - Hernandia sonora: 10.1016/0031-9422(95)00280-K
- 432643 - Isopyrum thalictroides: 10.1135/CCCC19870804
- 3415 - Liriodendron tulipifera: 10.1135/CCCC19951034
- 349509 - Magnolia obovata: 10.3390/MOLECULES18077739
- 248829 - Meconopsis cambrica: 10.1135/CCCC19961815
- 1451204 - Meconopsis robusta: 10.1135/CCCC19961815
- 1267437 - Meiogyne monosperma: 10.1021/NP50062A009
- 235744 - Meiogyne virgata: 10.1016/S0031-9422(00)81449-1
- 1609886 - Neolitsea konishii: 10.1002/JCCS.199200031
- 881603 - Ocotea lancifolia: 10.1016/J.FITOTE.2007.03.003
- 357464 - Papaver argemone: 10.1135/CCCC19881845
- 357466 - Papaver atlanticum: 10.1135/CCCC19862232
- 215227 - Papaver bracteatum: 10.1135/CCCC19851216
- 357469 - Papaver dubium: 10.1135/CCCC19891118
- 357470 - Papaver glaucum: 10.1135/CCCC19862232
- 1533249 - Papaver lecoqii:
- 22694 - Papaver orientale:
- 357473 - Papaver pavoninum: 10.1135/CCCC19881845
- 215228 - Papaver pseudo-orientale: 10.1135/CCCC19861752
- 33128 - Papaver rhoeas: 10.1135/CCCC19891118
- 152836 - Papaver tatricum: 10.1135/CCCC19851745
- 56864 - Stylophorum diphyllum: 10.1135/CCCC19840704
- 72189 - Stylophorum lasiocarpum: 10.1135/CCCC19911116
- 992813 - Xylopia parviflora: 10.1016/J.PHYTOCHEM.2006.07.011
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Qian Yan, Ruxia Li, Aiyi Xin, Yin Han, Yanxia Zhang, Junxi Liu, Wenguang Li, Duolong Di. Design, synthesis, and anticancer properties of isocorydine derivatives.
Bioorganic & medicinal chemistry.
2017 12; 25(24):6542-6553. doi:
10.1016/j.bmc.2017.10.027. [PMID: 29103873] - Yi-Nan Zhang, Xiang-Gen Zhong, Zong-Ping Zheng, Xu-Dong Hu, Jian-Ping Zuo, Li-Hong Hu. Discovery and synthesis of new immunosuppressive alkaloids from the stem of Fissistigma oldhamii (Hemsl.) Merr.
Bioorganic & medicinal chemistry.
2007 Jan; 15(2):988-96. doi:
10.1016/j.bmc.2006.10.034. [PMID: 17081761] - Yinde Qi, Yongjian Yang. [Medicinal plant resources of Trib. Isopyreae and prospects of exploitation].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2002 Feb; 25(2):87-9. doi:
". [PMID: 12599404] - V Misík, L Bezáková, L Máleková, D Kostálová. Lipoxygenase inhibition and antioxidant properties of protoberberine and aporphine alkaloids isolated from Mahonia aquifolium.
Planta medica.
1995 Aug; 61(4):372-3. doi:
10.1055/s-2006-958107. [PMID: 7480190]