Fluazifop (BioDeep_00000001155)

 

Secondary id: BioDeep_00000397709

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid

化学式: C15H12F3NO4 (327.0718388)
中文名称: 氟草灵
谱图信息: 最多检出来源 Homo sapiens(blood) 98.72%

分子结构信息

SMILES: CC(C(=O)O)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F
InChI: InChI=1S/C15H12F3NO4/c1-9(14(20)21)22-11-3-5-12(6-4-11)23-13-7-2-10(8-19-13)15(16,17)18/h2-9H,1H3,(H,20,21)

描述信息

D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals

同义名列表

6 个代谢物同义名

2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid; 2-(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoate; Fluazifop, (+-)-isomer; Fluazifop, sodium salt; Fluazifop; Fluazifop



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Xiaoyong Luo, Zhihang Liu, Yukari Sunohara, Hiroshi Matsumoto, Pingliang Li. Involvement of H2O2 in fluazifop-P-butyl-induced cell death in bristly starbur seedlings. Pesticide biochemistry and physiology. 2017 Nov; 143(?):258-264. doi: 10.1016/j.pestbp.2016.12.007. [PMID: 29183601]
  • Ayokanmi Ore, Ebenezer Tunde Olayinka. Fluazifop- p-butyl, an aryloxyphenoxypropionate herbicide, diminishes renal and hepatic functions and triggers testicular oxidative stress in orally exposed rats. Toxicology and industrial health. 2017 May; 33(5):406-415. doi: 10.1177/0748233716657763. [PMID: 27378613]
  • Thye San Cha, Mohamed Ghazani Najihah, Ismail Bin Sahid, Tse Seng Chuah. Molecular basis for resistance to ACCase-inhibiting fluazifop in Eleusine indica from Malaysia. Pesticide biochemistry and physiology. 2014 May; 111(?):7-13. doi: 10.1016/j.pestbp.2014.04.011. [PMID: 24861927]
  • R Alarcón-Reverte, S R Moss. Resistance to ACCase-inhibiting herbicides in the weed Lolium multiflorum. Communications in agricultural and applied biological sciences. 2008; 73(4):899-902. doi: . [PMID: 19226841]
  • Qin Yu, Alberto Collavo, Ming-Qi Zheng, Mechelle Owen, Maurizio Sattin, Stephen B Powles. Diversity of acetyl-coenzyme A carboxylase mutations in resistant Lolium populations: evaluation using clethodim. Plant physiology. 2007 Oct; 145(2):547-58. doi: 10.1104/pp.107.105262. [PMID: 17720757]
  • Stephen R Moss, Kay M Cocker, Amanda C Brown, Linda Hall, Linda M Field. Characterisation of target-site resistance to ACCase-inhibiting herbicides in the weed Alopecurus myosuroides (black-grass). Pest management science. 2003 Feb; 59(2):190-201. doi: 10.1002/ps.623. [PMID: 12587873]
  • Ahmed A Tantawy. Effect of two herbicides on some biological and biochemical parameters of Biomphalaria alexandrina. Journal of the Egyptian Society of Parasitology. 2002 Dec; 32(3):837-47. doi: ". [PMID: 12512816]
  • R A Page, S Okada, J L Harwood. Acetyl-CoA carboxylase exerts strong flux control over lipid synthesis in plants. Biochimica et biophysica acta. 1994 Jan; 1210(3):369-72. doi: 10.1016/0005-2760(94)90242-9. [PMID: 7905749]
  • N W McCracken, P G Blain, F M Williams. Human xenobiotic metabolizing esterases in liver and blood. Biochemical pharmacology. 1993 Oct; 46(7):1125-9. doi: 10.1016/0006-2952(93)90459-a. [PMID: 8216361]
  • D Herbert, D J Cole, K E Pallett, J L Harwood. Differential sensitivity of lipid metabolism in monocotyledons to grass-specific herbicides. Biochemical Society transactions. 1993 May; 21(2):183S. doi: 10.1042/bst021183s. [PMID: 8359436]
  • J D Ramsey, B H Woollen, T R Auton, P L Batten, J E Leeser. Pharmacokinetics of fluazifop-butyl in human volunteers. II: Dermal dosing. Human & experimental toxicology. 1992 Jul; 11(4):247-54. doi: 10.1177/096032719201100402. [PMID: 1354971]
  • B H Woollen, T B Hart, P L Batten, W J Laird, D S Davies, C T Dollery. Oral pharmacokinetics of fluazifop-butyl in human volunteers. Human & experimental toxicology. 1991 Jan; 10(1):39-43. doi: 10.1177/096032719101000107. [PMID: 1673623]
  • B L Worobey, J B Shields. Determination of fluazifop-butyl and fluazifop acid in soybeans and soybean oil using liquid chromatography with oxidative amperometric detection. Journal - Association of Official Analytical Chemists. 1989 Mar; 72(2):368-71. doi: ". [PMID: 2708288]
  • K A Walker, S M Ridley, J L Harwood. Effects of the selective herbicide fluazifop on fatty acid synthesis in pea (Pisum sativum) and barley (Hordeum vulgare). The Biochemical journal. 1988 Sep; 254(3):811-7. doi: 10.1042/bj2540811. [PMID: 3196294]
  • K A Walker, S M Ridley, T Lewis, J L Harwood. Fluazifop, a grass-selective herbicide which inhibits acetyl-CoA carboxylase in sensitive plant species. The Biochemical journal. 1988 Aug; 254(1):307-10. doi: 10.1042/bj2540307. [PMID: 2902848]