Hydroxysanguinarine (BioDeep_00000001021)

human metabolite PANOMIX_OTCML-2023 blood metabolite

代谢物信息卡片

24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21)-octaen-23-one

化学式: C20H13NO5 (347.07936880000005)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 54.21%

分子结构信息

SMILES: c12c(cc3c(c1)ccc1c3n(c(=O)c3c1ccc1c3OCO1)C)OCO2
InChI: InChI=1S/C20H13NO5/c1-21-18-12(3-2-10-6-15-16(7-13(10)18)25-8-24-15)11-4-5-14-19(26-9-23-14)17(11)20(21)22/h2-7H,8-9H2,1H3

描述信息

Hydroxysanguinarine is a benzophenanthridine alkaloid.
Hydroxysanguinarine is a natural product found in Fumaria indica, Fumaria parviflora, and other organisms with data available.

同义名列表

11 个代谢物同义名

24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21)-octaen-23-one; 24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-1,3,8,10,12,14,16,21-octaen-23-one; 13-Methyl-[1,3]dioxolo[4,5:4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-14(13H)-one; (1,3)Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridin-14(13H)-one, 13-methyl-; 13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one; Hydroxysanguinarine; 8-Oxosanguinarine; Oxosanguinarine; Oxysanguinarine; dicyanide; AC1L9F22

数据库引用编号

15 个数据库交叉引用编号

ChEBI: CHEBI:31679
KEGG: C12222
PubChem: 443716
HMDB: HMDB0253291
Metlin: METLIN69373
ChEMBL: CHEMBL4785846
MeSH: oxysanguinarine
ChemIDplus: 0000548301
KNApSAcK: C00024659
CAS: 548-30-1
medchemexpress: HY-N7642
PMhub: MS000022937
PubChem: 14367
NIKKAJI: J396.552J
RefMet: Hydroxysanguinarine

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

31 个相关的物种来源信息

1464615 Fumaria indica:
367484 Fumaria vaillantii:
1464625 Fumaria parviflora:
215227 Papaver bracteatum: 10.1016/0031-9422(88)80112-2
1475375 Bocconia arborea: 10.1002/PCA.612
3469 Papaver somniferum:
71251 Chelidonium majus:
38924 Sarcocapnos enneaphylla: 10.1016/S0031-9422(00)95198-7
185659 Sarcocapnos crassifolia:
54433 Ichtyoselmis macrantha: 10.1007/S10600-013-0801-Z
39361 Pteridophyllum racemosum: 10.1016/S0031-9422(00)88990-6
367483 Dactylicapnos torulosa: 10.1016/S0031-9422(00)97106-1
38903 Corydalis pallida: 10.1248/YAKUSHI1947.91.1_101
1852778 Corydalis balansae: 10.1055/S-1999-14090
3472 Sanguinaria canadensis: 10.1135/CCCC19601667
1464615 Fumaria indica:
367484 Fumaria vaillantii:
1464625 Fumaria parviflora:
215227 Papaver bracteatum: 10.1016/0031-9422(88)80112-2
1475375 Bocconia arborea: 10.1002/PCA.612
3469 Papaver somniferum:
71251 Chelidonium majus:
38924 Sarcocapnos enneaphylla: 10.1016/S0031-9422(00)95198-7
185659 Sarcocapnos crassifolia:
54433 Ichtyoselmis macrantha: 10.1007/S10600-013-0801-Z
39361 Pteridophyllum racemosum: 10.1016/S0031-9422(00)88990-6
367483 Dactylicapnos torulosa: 10.1016/S0031-9422(00)97106-1
38903 Corydalis pallida: 10.1248/YAKUSHI1947.91.1_101
1852778 Corydalis balansae: 10.1055/S-1999-14090
3472 Sanguinaria canadensis: 10.1135/CCCC19601667
9606 Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Liang Jiang, Xiaolu Wang, Yuting Wang, Fang Xu, Zhang Zhang, Ke Ding, Xiaoyun Lu. The synthesis and biological evaluation of sanguinarine derivatives as anti-non-small cell lung cancer agents. RSC medicinal chemistry. 2020 Feb; 11(2):293-296. doi: 10.1039/c9md00494g. [PMID: 33479636]
T Fukushima. [Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 1975 Jul; 71(5):457-62. doi: . [PMID: 280]