Biological Pathway: BioCyc:META_NONOXIPENT-PWY

pentose phosphate pathway (non-oxidative branch) related metabolites

find 22 related metabolites which is associated with the biological pathway pentose phosphate pathway (non-oxidative branch)

this pathway object is a conserved pathway across multiple organism.

View the spectrum consensus network of the metabolites related with current biological pathway.

Superoxide is the anionic form O2. It is important as the product of the one-electron reduction of dioxygen (oxygen gas), which occurs widely in nature. With one unpaired electron, the superoxide ion is a free radical. It is also paramagnetic. The biological toxicity of superoxide is due to its capacity to inactivate iron-sulfur cluster containing enzymes (which are critical in a wide variety of metabolic pathways), thereby liberating free iron in the cell, which can undergo fenton-chemistry and generate the highly reactive hydroxyl radical. In its HO2 form, superoxide can also initiate lipid peroxidation of polyunsaturated fatty acids. It also reacts with carbonyl compounds and halogenated carbons to create toxic peroxy radicals. As such, superoxide is a main cause of oxidative stress. Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to Methemoglobin. Because superoxide is toxic, nearly all organisms living in the presence of oxygen contain isoforms of the superoxide scavenging enzyme, superoxide dismutase, or SOD. SOD is an extremely efficient enzyme; it catalyzes the neutralization of superoxide nearly as fast as the two can diffuse together spontaneously in solution. Genetic inactivation ("knockout") of SOD produces deleterious phenotypes in organisms ranging from bacteria to mice. The latter species dies around 21 days after birth if the mitochondrial variant of SOD (Mn-SOD) is inactivated, and suffers from multiple pathologies, including reduced lifespan, liver cancer, muscle atrophy, cataracts and female infertility when the cytoplasmic (Cu, Zn -SOD) variant is inactivated. With one unpaired electron, the superoxide ion is a free radical and therefore paramagnetic. In living organisms, superoxide dismutase protects the cell from the deleterious effects of superoxides. Superoxide is the anionic form O2. It is important as the product of the one-electron reduction of dioxygen (oxygen gas), which occurs widely in nature. With one unpaired electron, the superoxide ion is a free radical. It is also paramagnetic. The biological toxicity of superoxide is due to its capacity to inactivate iron-sulfur cluster containing enzymes (which are critical in a wide variety of metabolic pathways), thereby liberating free iron in the cell, which can undergo fenton-chemistry and generate the highly reactive hydroxyl radical. In its HO2 form, superoxide can also initiate lipid peroxidation of polyunsaturated fatty acids. It also reacts with carbonyl compounds and halogenated carbons to create toxic peroxy radicals. As such, superoxide is a main cause of oxidative stress.; Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to Methemoglobin. D009676 - Noxae > D016877 - Oxidants > D013481 - Superoxides D009676 - Noxae > D016877 - Oxidants > D010545 - Peroxides

Manganous cation

Mn+2 (54.938)

Glycerose

α,β-Dihydroxypropionaldehyde

C3H6O3 (90.0317)

DL-Glyceraldehyde is a monosaccharide. DL-Glyceraldehyde is the simplest aldose. DL-Glyceraldehyde can be used for various biochemical studies[1].

The L-enantiomer of glyceraldehyde.

Biological Pathway: BioCyc:META_NONOXIPENT-PWY

pentose phosphate pathway (non-oxidative branch) related metabolites

Magnesium

Superoxide

Manganous cation

Glycerose

Hydrogen phosphate

2-Amino-2-hydroxymethyl-propane-1,3-diol

Ferrous cation

Adenosine-5-monophosphate(2-)

Thiamine(1+) diphosphate(3-)

Xylulose 5-phosphate

D-glyceraldehyde 3-phosphate(2-)

5-O-phosphonato-D-ribulose

beta-D-fructofuranose 6-phosphate(2-)

D-erythrose 4-phosphate(2-)

aldehydo-D-arabinose 5-phosphate(2-)

D-Sedoheptulose 7-phosphate

D-ribofuranose 5-phosphate(2-)

MeO-TPP

2-Iodoacetate

Magnesium Cation

Superoxide

L-glyceraldehyde