NCBI Taxonomy: 282607

Drummondita (ncbi_taxid: 282607)

found 45 associated metabolites at genus taxonomy rank level.

Ancestor: Zanthoxyloideae

Child Taxonomies: Drummondita fulva, Drummondita calida, Drummondita ericoides, Drummondita hassellii, Drummondita longifolia

Hesperidin

(S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one

C28H34O15 (610.1898)


Hesperidin is an abundant and inexpensive by-product of Citrus cultivation and is the major flavonoid in sweet orange and lemon. In young immature oranges it can account for up to 14\\\\% of the fresh weight of the fruit. Hesperidin is an abundant and inexpensive by-product of Citrus cultivation and is the major flavonoid in sweet orange and lemon. In young immature oranges it can account for up to 14\\\\% of the fresh weight of the fruit due to vitamin C deficiency such as bruising due to capillary fragility were found in early studies to be relieved by crude vitamin C extract but not by purified vitamin C. The bioflavonoids, formerly called "vitamin P", were found to be the essential components in correcting this bruising tendency and improving the permeability and integrity of the capillary lining. These bioflavonoids include hesperidin, citrin, rutin, flavones, flavonols, catechin and quercetin. Of historical importance is the observation that "citrin", a mixture of two flavonoids, eriodictyol and hesperidin, was considered to possess a vitamin-like activity, as early as in 1949. Hesperidin deficiency has since been linked with abnormal capillary leakiness as well as pain in the extremities causing aches, weakness and night leg cramps. Supplemental hesperidin also helps in reducing oedema or excess swelling in the legs due to fluid accumulation. As with other bioflavonoids, hesperidin works best when administered concomitantly with vitamin C. No signs of toxicity have been observed with normal intake of hesperidin. Hesperidin was first discovered in 1827, by Lebreton, but not in a pure state and has been under continuous investigation since then (PMID:11746857). Hesperidin is a disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a mutagen. It is a disaccharide derivative, a member of 3-hydroxyflavanones, a dihydroxyflavanone, a monomethoxyflavanone, a flavanone glycoside, a member of 4-methoxyflavanones and a rutinoside. It is functionally related to a hesperetin. Hesperidin is a flavan-on glycoside found in citrus fruits. Hesperidin is a natural product found in Ficus erecta var. beecheyana, Citrus tankan, and other organisms with data available. A flavanone glycoside found in CITRUS fruit peels. See also: Tangerine peel (part of). Found in most citrus fruits and other members of the Rutaceae, also in Mentha longifolia Acquisition and generation of the data is financially supported in part by CREST/JST. COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials relative retention time with respect to 9-anthracene Carboxylic Acid is 0.770 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.767 [Raw Data] CB217_Hesperidin_pos_50eV_CB000076.txt [Raw Data] CB217_Hesperidin_pos_20eV_CB000076.txt [Raw Data] CB217_Hesperidin_pos_30eV_CB000076.txt [Raw Data] CB217_Hesperidin_pos_10eV_CB000076.txt [Raw Data] CB217_Hesperidin_pos_40eV_CB000076.txt [Raw Data] CB217_Hesperidin_neg_20eV_000038.txt [Raw Data] CB217_Hesperidin_neg_50eV_000038.txt [Raw Data] CB217_Hesperidin_neg_10eV_000038.txt [Raw Data] CB217_Hesperidin_neg_30eV_000038.txt [Raw Data] CB217_Hesperidin_neg_40eV_000038.txt Annotation level-1 Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities[1][2]. Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities[1][2].

   

Skimmianine

4,7,8-trimethoxy-furo(2,3-b)quinoline

C14H13NO4 (259.0845)


Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].

   

Dictamnine

4-methoxyfuro(2,3-b)quinoline

C12H9NO2 (199.0633)


Dictamnine (Dictamine) exhibits cytotoxicity to human cervical and colon cancer cells and also has antibacterial and antifungal activities. Dictamnine (Dictamine) exhibits cytotoxicity to human cervical and colon cancer cells and also has antibacterial and antifungal activities.

   

Santin

2- (4-Methoxyphenyl) -5,7-dihydroxy-3,6-dimethoxy-4H-1-benzopyran-4-one

C18H16O7 (344.0896)


A trimethoxyflavone that is flavone substituted by methoxy groups at positions 3, 6 and 4 and hydroxy groups at positions 5 and 7 respectively.

   

Tambulin

3,5-dihydroxy-7,8-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

C18H16O7 (344.0896)


Tambulin, also known as herbacetin 7,8,4-trimethyl ether, is a member of the class of compounds known as flavonols. Flavonols are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position. Thus, tambulin is considered to be a flavonoid lipid molecule. Tambulin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Tambulin can be found in sunflower, which makes tambulin a potential biomarker for the consumption of this food product.

   

gamma-Fagarine

4,8-Dimethoxyfuro[2,3-b]quinoline; 8-Methoxydictamnine; Fagarine

C13H11NO3 (229.0739)


Gamma-Fagarine is an organic heterotricyclic compound, an organonitrogen heterocyclic compound and an oxacycle. gamma-Fagarine is a natural product found in Haplophyllum bucharicum, Haplophyllum griffithianum, and other organisms with data available. gamma-Fagarine is found in fruits. gamma-Fagarine is an alkaloid from Aegle marmelos (bael fruit

   

Maculosidine

Furo(2,3-b)quinoline, 4,6,8-trimethoxy-

C14H13NO4 (259.0845)


   

dictamine

4-27-00-02030 (Beilstein Handbook Reference)

C12H9NO2 (199.0633)


Dictamnine is an oxacycle, an organonitrogen heterocyclic compound, an organic heterotricyclic compound and an alkaloid antibiotic. Dictamnine is a natural product found in Haplophyllum bucharicum, Haplophyllum cappadocicum, and other organisms with data available. A furoquinoline alkaloid, dictamnine, is very common within the family Rutaceae. It is the main alkaloid in the roots of Dictamnus albus and responsible for the mutagenicity of the drug derived from crude extracts. Dictamnine was also reported to be a phototoxic and photomutagenic compound. It participates in the severe skin phototoxicity of the plant. Dictamnine (Dictamine) exhibits cytotoxicity to human cervical and colon cancer cells and also has antibacterial and antifungal activities. Dictamnine (Dictamine) exhibits cytotoxicity to human cervical and colon cancer cells and also has antibacterial and antifungal activities.

   

Spathulenol

1H-Cycloprop(e)azulen-7-ol, decahydro-1,1,7-trimethyl-4-methylene-, (1aR-(1aalpha,4aalpha,7beta,7abeta,7balpha))-

C15H24O (220.1827)


Spathulenol is a tricyclic sesquiterpenoid that is 4-methylidenedecahydro-1H-cyclopropa[e]azulene carrying three methyl substituents at positions 1, 1 and 7 as well as a hydroxy substituent at position 7. It has a role as a volatile oil component, a plant metabolite, an anaesthetic and a vasodilator agent. It is a sesquiterpenoid, a carbotricyclic compound, a tertiary alcohol and an olefinic compound. Spathulenol is a natural product found in Xylopia aromatica, Xylopia emarginata, and other organisms with data available. See also: Chamomile (part of). A tricyclic sesquiterpenoid that is 4-methylidenedecahydro-1H-cyclopropa[e]azulene carrying three methyl substituents at positions 1, 1 and 7 as well as a hydroxy substituent at position 7. Spathulenol is found in alcoholic beverages. Spathulenol is a constituent of Salvia sclarea (clary sage).

   

Skimmianine

InChI=1/C14H13NO4/c1-16-10-5-4-8-11(13(10)18-3)15-14-9(6-7-19-14)12(8)17-2/h4-7H,1-3H

C14H13NO4 (259.0845)


Skimmianine is an organonitrogen heterocyclic compound, an organic heterotricyclic compound, an oxacycle and an alkaloid antibiotic. Skimmianine is a natural product found in Haplophyllum bucharicum, Haplophyllum cappadocicum, and other organisms with data available. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].

   
   

Pteleine

4,6-dimethoxyfuro[2,3-b]Quinoline, 9ci

C13H11NO3 (229.0739)


Pteleine is found in herbs and spices. Pteleine is an alkaloid tentatively identified in cells of Ruta graveolens (rue) grown in continuous light in liq. medium. Alkaloid tentatively identified in cells of Ruta graveolens (rue) grown in continuous light in liq. medium. Pteleine is found in herbs and spices.

   

5-Hydroxyauranetin

5-Hydroxy-3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-1-Benzopyran-4-one

C20H20O8 (388.1158)


5-Hydroxyauranetin is found in citrus. 5-Hydroxyauranetin is a constituent of Citrus aurantium (Seville orange). Constituent of Citrus aurantium (Seville orange). 5-Hydroxyauranetin is found in citrus.

   

Herbacetin pentamethyl ether

3,5,7,8-Tetramethoxy-2- (4-methoxyphenyl) -4H-1-benzopyran-4-one

C20H20O7 (372.1209)


   

Araneosol

5,7-Dihydroxy-3,6,8-trimethoxy-2- (4-methoxyphenyl) -4H-1-benzopyran-4-one

C19H18O8 (374.1002)


   

3,5,6,7,8,4-Hexamethoxyflavone

3,5,6,7,8-Pentamethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one

C21H22O8 (402.1315)


   

5-Hydroxyauranetin

5-Hydroxy-3,6,7,8-tetramethoxy-2- (4-methoxyphenyl) -4H-1-Benzopyran-4-one

C20H20O8 (388.1158)


   

Tambulin

3,5-Dihydroxy-4,7,8-trimethoxyflavone

C18H16O7 (344.0896)


A member of the class of flavonols that is flavonol substituted by an additional hydroxy group at position 5 and methoxy groups at positions 7, 8 and 4 respectively.

   

3,5,7,8,4-Pentamethoxyflavone

3,5,7,8,4-Pentamethoxyflavone

C20H20O7 (372.1209)


   

Spathulenol

Spathulenol

C15H24O (220.1827)


Constituent of Salvia sclarea (clary sage). Spathulenol is found in many foods, some of which are tarragon, spearmint, common sage, and tea.

   

4-methoxy-1-methylquinolin-2-one

4-methoxy-1-methylquinolin-2-one

C11H11NO2 (189.079)


   

3-Methoxytangeretin

3-Methoxytangeretin

C21H22O8 (402.1315)


   

Hesperidin

(S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)chroman-4-one

C28H34O15 (610.1898)


Hesperidin is a disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a mutagen. It is a disaccharide derivative, a member of 3-hydroxyflavanones, a dihydroxyflavanone, a monomethoxyflavanone, a flavanone glycoside, a member of 4-methoxyflavanones and a rutinoside. It is functionally related to a hesperetin. Hesperidin is a flavan-on glycoside found in citrus fruits. Hesperidin is a natural product found in Ficus erecta var. beecheyana, Citrus tankan, and other organisms with data available. A flavanone glycoside found in CITRUS fruit peels. See also: Tangerine peel (part of). A disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities[1][2]. Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities[1][2].

   

Skimmianine

Skimmianine

C14H13NO4 (259.0845)


Origin: Plant; SubCategory_DNP: Alkaloids derived from anthranilic acid, Quinoline alkaloids relative retention time with respect to 9-anthracene Carboxylic Acid is 1.053 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.048 Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].

   

4,6-dimethoxyfuro[2,3-b]quinoline

NCGC00385496-01!4,6-dimethoxyfuro[2,3-b]quinoline

C13H11NO3 (229.0739)


   
   

5-hydroxy-3,6,7-trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

5-hydroxy-3,6,7-trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

C19H18O7 (358.1052)


   

5,7-dihydroxy-3,6-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

5,7-dihydroxy-3,6-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

C18H16O7 (344.0896)


   

Ptelein

4,6-dimethoxyfuro[2,3-b]Quinoline, 9ci

C13H11NO3 (229.0739)


   

γ-Fagarine

gamma-Fagarine

C13H11NO3 (229.0739)


   

dictamine

4-27-00-02030 (Beilstein Handbook Reference)

C12H9NO2 (199.0633)


Dictamnine (Dictamine) exhibits cytotoxicity to human cervical and colon cancer cells and also has antibacterial and antifungal activities. Dictamnine (Dictamine) exhibits cytotoxicity to human cervical and colon cancer cells and also has antibacterial and antifungal activities.

   

Skimmianin

InChI=1\C14H13NO4\c1-16-10-5-4-8-11(13(10)18-3)15-14-9(6-7-19-14)12(8)17-2\h4-7H,1-3H

C14H13NO4 (259.0845)


Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1]. Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity[1].

   

Fagarine

4-27-00-02211 (Beilstein Handbook Reference)

C13H11NO3 (229.0739)


   

Ciratin

(2S)-5-hydroxy-2-(3-hydroxy-4-methoxy-phenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxymethyl]tetrahydropyran-2-yl]oxy-chroman-4-one

C28H34O15 (610.1898)


COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities[1][2]. Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities[1][2].

   

methyl 3-(5-methoxy-2,2-dimethylchromen-6-yl)prop-2-enoate

methyl 3-(5-methoxy-2,2-dimethylchromen-6-yl)prop-2-enoate

C16H18O4 (274.1205)


   

6-hydroxy-5-methoxy-7-[(3-methylbut-2-en-1-yl)oxy]chromen-2-one

6-hydroxy-5-methoxy-7-[(3-methylbut-2-en-1-yl)oxy]chromen-2-one

C15H16O5 (276.0998)


   

3-{[(2r)-3,3-dimethyloxiran-2-yl]methyl}-4-methoxy-1-methylquinolin-2-one

3-{[(2r)-3,3-dimethyloxiran-2-yl]methyl}-4-methoxy-1-methylquinolin-2-one

C16H19NO3 (273.1365)


   

5-methoxy-6,7-bis[(3-methylbut-2-en-1-yl)oxy]chromen-2-one

5-methoxy-6,7-bis[(3-methylbut-2-en-1-yl)oxy]chromen-2-one

C20H24O5 (344.1624)


   

3-{5,7-dimethoxy-2,2-dimethyl-6-[(1e)-3-methylbuta-1,3-dien-1-yl]chromen-8-yl}propanoic acid

3-{5,7-dimethoxy-2,2-dimethyl-6-[(1e)-3-methylbuta-1,3-dien-1-yl]chromen-8-yl}propanoic acid

C21H26O5 (358.178)


   

5-hydroxy-6,7-bis[(3-methylbut-2-en-1-yl)oxy]chromen-2-one

5-hydroxy-6,7-bis[(3-methylbut-2-en-1-yl)oxy]chromen-2-one

C19H22O5 (330.1467)


   

(2s)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one

(2s)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4s,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-2,3-dihydro-1-benzopyran-4-one

C28H34O15 (610.1898)


   

3-[5,7-dimethoxy-2,2-dimethyl-6-(3-methylbuta-1,3-dien-1-yl)chromen-8-yl]propanoic acid

3-[5,7-dimethoxy-2,2-dimethyl-6-(3-methylbuta-1,3-dien-1-yl)chromen-8-yl]propanoic acid

C21H26O5 (358.178)


   

4-methoxy-1-methyl-3-(3-methylbut-2-en-1-yl)quinolin-2-one

4-methoxy-1-methyl-3-(3-methylbut-2-en-1-yl)quinolin-2-one

C16H19NO2 (257.1416)


   

3-{5-methoxy-2,2,8,8-tetramethylpyrano[3,2-g]chromen-10-yl}propanoic acid

3-{5-methoxy-2,2,8,8-tetramethylpyrano[3,2-g]chromen-10-yl}propanoic acid

C20H24O5 (344.1624)


   

methyl (2e)-3-(5-methoxy-2,2-dimethylchromen-6-yl)prop-2-enoate

methyl (2e)-3-(5-methoxy-2,2-dimethylchromen-6-yl)prop-2-enoate

C16H18O4 (274.1205)