NCBI Taxonomy: 138277

Aspergillus melleus (ncbi_taxid: 138277)

found 28 associated metabolites at species taxonomy rank level.

Ancestor: Aspergillus

Child Taxonomies: none taxonomy data.

Ochratoxin A

(2S)-2-{[(3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-carbonyl]amino}-3-phenylpropanoic acid

C20H18ClNO6 (403.0823)


Ochratoxin A is found in barley. Mycotoxin. Ochratoxin A is produced by Aspergillus melleus, Aspergillus sulphureus and Penicillium viridicatum.Potential contaminant of foodstuffs, especially cereals. Ochratoxin A is found in stored grain products in UK (1997).Ochratoxin A, a toxin produced by Aspergillus ochraceus and Penicillium verrucosum, is one of the most abundant food-contaminating mycotoxins in the world. Human exposure occurs mainly through consumption of improperly stored food products, particularly contaminated grain and pork products, as well as coffee, wine grapes and dried grapes. The toxin has been found in the tissues and organs of animals, including human blood and breast milk. Ochratoxin A toxicity has large species- and sex-specific differences Mycotoxin. Production by Aspergillus melleus, Aspergillus sulphureus and Penicillium viridicatum.Potential contaminant of foodstuffs, especially cereals. Found in stored grain products in UK (1997) D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D009676 - Noxae > D011042 - Poisons > D009793 - Ochratoxins D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins D000077264 - Calcium-Regulating Hormones and Agents D009676 - Noxae > D002273 - Carcinogens D049990 - Membrane Transport Modulators

   

penicillic acid

(2E)-3-methoxy-5-methyl-4-oxohexa-2,5-dienoic acid

C8H10O4 (170.0579)


D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins CONFIDENCE isolated standard

   

(R)N-(5-Chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)phenylalanine

2-{[(5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-yl)(hydroxy)methylidene]amino}-3-phenylpropanoic acid

C20H18ClNO6 (403.0823)


   

Penicillic acid

3-Methoxy-5-methyl-4-oxo-2,5-hexadienoic acid

C8H10O4 (170.0579)


   

Mellein

(3R)-8-hydroxy-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one

C10H10O3 (178.063)


Mellein, also known as (R)-mellein, is a member of the class of compounds known as 2-benzopyrans. 2-benzopyrans are organic aromatic compounds that 1-benzopyran, a bicyclic compound made up of a benzene ring fused to a pyran, so that the oxygen atom is at the 2-position. Mellein is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Mellein can be found in cocoa powder, which makes mellein a potential biomarker for the consumption of this food product. Mellein is a dihydroisocoumarin, a phenolic compound produced by Aspergillus ochraceus .

   

Mellein

8-hydroxy-3-methyl-3,4-dihydroisochromen-1-one

C10H10O3 (178.063)


D009676 - Noxae > D011042 - Poisons > D009793 - Ochratoxins D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins CONFIDENCE isolated standard

   

cis-4-Hydroxymellein

cis-3S,4S-4-Hydroxymellein

C10H10O4 (194.0579)


   

Aspyrone

Aspyrone

C9H12O4 (184.0736)


A member of the class of 2-pyranones that is 5,6-dihydro-2H-pyran-2-one in which the hydrogens at positions 3, 5S and 6R are replaced by (2S,3S)-3-methyloxiran-2-yl, hydroxy and methyl groups, respectively. It is a fungal metabolite isolated from Aspergillus melleus and exhibits nematicidal, antibacterial and antifungal properties.

   

Ochratoxin A

NCGC00162403-05_C20H18ClNO6_L-Phenylalanine, N-[[(3R)-5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-

C20H18ClNO6 (403.0823)


A phenylalanine derivative resulting from the formal condensation of the amino group of L-phenylalanine with the carboxy group of (3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-carboxylic acid (ochratoxin alpha). It is among the most widely occurring food-contaminating mycotoxins, produced by Aspergillus ochraceus, Aspergillus carbonarius and Penicillium verrucosum. D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D009676 - Noxae > D011042 - Poisons > D009793 - Ochratoxins D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins D000077264 - Calcium-Regulating Hormones and Agents D009676 - Noxae > D002273 - Carcinogens D049990 - Membrane Transport Modulators CONFIDENCE standard compound; INTERNAL_ID 5966 CONFIDENCE Reference Standard (Level 1)

   

(±)-Mellein

(3R)-8-hydroxy-3-methyl-3,4-dihydro-1H-2-benzopyran-1-one

C10H10O3 (178.063)


D009676 - Noxae > D011042 - Poisons > D009793 - Ochratoxins D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins

   

(3s-cis)-4-hydroxymellein

(3s-cis)-4-hydroxymellein

C10H10O4 (194.0579)


   

(5s,6r)-5-hydroxy-6-methyl-3-[(2s,3r)-3-methyloxiran-2-yl]-5,6-dihydropyran-2-one

(5s,6r)-5-hydroxy-6-methyl-3-[(2s,3r)-3-methyloxiran-2-yl]-5,6-dihydropyran-2-one

C9H12O4 (184.0736)


   

3-methyl-n-[(1z)-2-[7-(2-methylbut-3-en-2-yl)-1h-indol-3-yl]ethenyl]-2-(n-methylacetamido)butanimidic acid

3-methyl-n-[(1z)-2-[7-(2-methylbut-3-en-2-yl)-1h-indol-3-yl]ethenyl]-2-(n-methylacetamido)butanimidic acid

C23H31N3O2 (381.2416)


   

(5r)-5-[(1s)-1-hydroxyethyl]-3-[(2s,3s)-3-methyloxiran-2-yl]-5h-furan-2-one

(5r)-5-[(1s)-1-hydroxyethyl]-3-[(2s,3s)-3-methyloxiran-2-yl]-5h-furan-2-one

C9H12O4 (184.0736)


   

3-methyl-n-{2-[7-(2-methylbut-3-en-2-yl)-1h-indol-3-yl]ethenyl}-2-(n-methylacetamido)butanimidic acid

3-methyl-n-{2-[7-(2-methylbut-3-en-2-yl)-1h-indol-3-yl]ethenyl}-2-(n-methylacetamido)butanimidic acid

C23H31N3O2 (381.2416)


   

(5r,6s)-5-hydroxy-6-methyl-3-[(2r,3r)-3-methyloxiran-2-yl]-5,6-dihydropyran-2-one

(5r,6s)-5-hydroxy-6-methyl-3-[(2r,3r)-3-methyloxiran-2-yl]-5,6-dihydropyran-2-one

C9H12O4 (184.0736)


   

5-(1-hydroxyethyl)-3-(3-methyloxiran-2-yl)-5h-furan-2-one

5-(1-hydroxyethyl)-3-(3-methyloxiran-2-yl)-5h-furan-2-one

C9H12O4 (184.0736)


   

(5r)-5-hydroxy-4-methoxy-5-(prop-1-en-2-yl)furan-2-one

(5r)-5-hydroxy-4-methoxy-5-(prop-1-en-2-yl)furan-2-one

C8H10O4 (170.0579)


   

(3r)-10-hydroxy-8-[(3r)-10-hydroxy-7-methoxy-3-methyl-1,6,9-trioxo-3h,4h-naphtho[2,3-c]pyran-8-yl]-7-methoxy-3-methyl-3h,4h-naphtho[2,3-c]pyran-1,6,9-trione

(3r)-10-hydroxy-8-[(3r)-10-hydroxy-7-methoxy-3-methyl-1,6,9-trioxo-3h,4h-naphtho[2,3-c]pyran-8-yl]-7-methoxy-3-methyl-3h,4h-naphtho[2,3-c]pyran-1,6,9-trione

C30H22O12 (574.1111)


   

5-hydroxy-6-methyl-3-(3-methyloxiran-2-yl)-5,6-dihydropyran-2-one

5-hydroxy-6-methyl-3-(3-methyloxiran-2-yl)-5,6-dihydropyran-2-one

C9H12O4 (184.0736)


   

(5s)-5-hydroxy-5-isopropyl-4-methoxyfuran-2-one

(5s)-5-hydroxy-5-isopropyl-4-methoxyfuran-2-one

C8H12O4 (172.0736)


   

(3r)-4,8-dihydroxy-3-methyl-3,4-dihydro-2-benzopyran-1-one

(3r)-4,8-dihydroxy-3-methyl-3,4-dihydro-2-benzopyran-1-one

C10H10O4 (194.0579)


   

5-hydroxy-5-isopropyl-4-methoxyfuran-2-one

5-hydroxy-5-isopropyl-4-methoxyfuran-2-one

C8H12O4 (172.0736)


   
   

10-hydroxy-8-{10-hydroxy-7-methoxy-3-methyl-1,6,9-trioxo-3h,4h-naphtho[2,3-c]pyran-8-yl}-7-methoxy-3-methyl-3h,4h-naphtho[2,3-c]pyran-1,6,9-trione

10-hydroxy-8-{10-hydroxy-7-methoxy-3-methyl-1,6,9-trioxo-3h,4h-naphtho[2,3-c]pyran-8-yl}-7-methoxy-3-methyl-3h,4h-naphtho[2,3-c]pyran-1,6,9-trione

C30H22O12 (574.1111)


   

(2s)-2-({[(3r)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-2-benzopyran-7-yl](hydroxy)methylidene}amino)-3-phenylpropanoic acid

(2s)-2-({[(3r)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-2-benzopyran-7-yl](hydroxy)methylidene}amino)-3-phenylpropanoic acid

C20H18ClNO6 (403.0823)


   

5-hydroxy-4-methoxy-5-(prop-1-en-2-yl)furan-2-one

5-hydroxy-4-methoxy-5-(prop-1-en-2-yl)furan-2-one

C8H10O4 (170.0579)


   

(3s)-8-hydroxy-3-methyl-3,4-dihydro-2-benzopyran-1-one

(3s)-8-hydroxy-3-methyl-3,4-dihydro-2-benzopyran-1-one

C10H10O3 (178.063)