Gene Association: OR2H2

UniProt Search: OR2H2 (PROTEIN_CODING)
Function Description: olfactory receptor family 2 subfamily H member 2

found 8 associated metabolites with current gene based on the text mining result from the pubmed database.

Salutaridine

(1S,9R)-3-hydroxy-4,13-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,10,13-pentaen-12-one

C19H21NO4 (327.1471)


Salutaridine is a morphinane alkaloid from the opium poppy, in which the 5,6,8,14-tetradehydromorphinan-7-one skeleton is substituted at position 4 by a hydroxyl group, positions 3 and 6 by methoxy groups and position N17 by a methyl group. An intermediate in the biosynthesis of narcotic analgesics such as morphine and codeine. It has a role as a metabolite and an anti-HBV agent. It is a conjugate base of a salutaridinium(1+). It derives from a hydride of a morphinan. Salutaridine is a natural product found in Sarcocapnos saetabensis, Platycapnos saxicola, and other organisms with data available. A morphinane alkaloid from the opium poppy, in which the 5,6,8,14-tetradehydromorphinan-7-one skeleton is substituted at position 4 by a hydroxyl group, positions 3 and 6 by methoxy groups and position N17 by a methyl group. An intermediate in the biosynthesis of narcotic analgesics such as morphine and codeine. D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids

   

(-)-Thebaine

10,14-dimethoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7(18),8,10,14,16-pentaene

C19H21NO3 (311.1521)


D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D003292 - Convulsants D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist > C1657 - Opiate D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics (-)-Thebaine is a minor constituent of opiu

   

Methionine sulfoximine

Butanoic acid, 2-amino-4-(S-methylsulfonimidoyl)- (9ci)

C5H12N2O3S (180.0569)


Methionine sulfoximine is found in flours treated with NCl3 as a produced of NCl3 action on wheat protein

   

Oripavine

14-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0¹,¹³.0⁵,¹⁷.0⁷,¹⁸]octadeca-7(18),8,10,14,16-pentaen-10-ol

C18H19NO3 (297.1365)


Alkaloid from opium poppy (Papaver somniferum). Oripavine is found in many foods, some of which are redcurrant, teff, muscadine grape, and date. D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids Oripavine is an alkaloid from opium poppy (Papaver somniferum

   

Isothebaine

4H-Dibenzo[de,g]quinolin-1-ol,5,6,6a,7-tetrahydro-2,11-dimethoxy-6-methyl-, (6aS)-

C19H21NO3 (311.1521)


   

METHIONINE SULFOXIMINE

(R-(R*,S*))-S-(3-Amino-3-carboxypropyl)-S-methylsulphoximide

C5H12N2O3S (180.0569)


A non-proteinogenic alpha-amino acid that is the sulfoximine derivative of methionine . KEIO_ID M114

   

thebaine

thebaine

C19H21NO3 (311.1521)


D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D003292 - Convulsants D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist > C1657 - Opiate D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics relative retention time with respect to 9-anthracene Carboxylic Acid is 0.549 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.537 IPB_RECORD: 2881; CONFIDENCE confident structure

   

Oripavine

Oripavine

C18H19NO3 (297.1365)


D002492 - Central Nervous System Depressants > D009294 - Narcotics > D053610 - Opiate Alkaloids A morphinane alkaloid with formula C18H19NO3. It is the major metabolite of thebaine.